HUE034752T2 - Antibody against human receptor protein tyrosine phosphatase - Google Patents

Antibody against human receptor protein tyrosine phosphatase Download PDF

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Publication number
HUE034752T2
HUE034752T2 HUE12722557A HUE12722557A HUE034752T2 HU E034752 T2 HUE034752 T2 HU E034752T2 HU E12722557 A HUE12722557 A HU E12722557A HU E12722557 A HUE12722557 A HU E12722557A HU E034752 T2 HUE034752 T2 HU E034752T2
Authority
HU
Hungary
Prior art keywords
seq
antibody
ser
cell
val
Prior art date
Application number
HUE12722557A
Other languages
English (en)
Hungarian (hu)
Inventor
Tomohide Yamazaki
Jing Zhao
Koji Ishida
Yasue Shibata
Minkwon Cho
Mayuki Endo
Original Assignee
Sbi Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sbi Biotech Co Ltd filed Critical Sbi Biotech Co Ltd
Publication of HUE034752T2 publication Critical patent/HUE034752T2/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5058Neurological cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Mycology (AREA)
HUE12722557A 2011-04-28 2012-04-27 Antibody against human receptor protein tyrosine phosphatase HUE034752T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011101752 2011-04-28

Publications (1)

Publication Number Publication Date
HUE034752T2 true HUE034752T2 (en) 2018-02-28

Family

ID=46147004

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE17174348A HUE054211T2 (hu) 2011-04-28 2012-04-27 Humán receptor típusú fehérje-tirozin-foszfatáz elleni antitest
HUE12722557A HUE034752T2 (en) 2011-04-28 2012-04-27 Antibody against human receptor protein tyrosine phosphatase

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE17174348A HUE054211T2 (hu) 2011-04-28 2012-04-27 Humán receptor típusú fehérje-tirozin-foszfatáz elleni antitest

Country Status (16)

Country Link
US (2) US9803026B2 (OSRAM)
EP (2) EP3232202B1 (OSRAM)
JP (2) JP6001557B2 (OSRAM)
KR (1) KR101873614B1 (OSRAM)
CN (1) CN103703372B (OSRAM)
AU (2) AU2012248158C1 (OSRAM)
CA (1) CA2834243C (OSRAM)
ES (2) ES2788183T3 (OSRAM)
HU (2) HUE054211T2 (OSRAM)
IL (1) IL229127A (OSRAM)
MX (1) MX352599B (OSRAM)
PL (2) PL3232202T3 (OSRAM)
PT (2) PT3232202T (OSRAM)
RU (2) RU2013152816A (OSRAM)
SG (3) SG10201503257WA (OSRAM)
WO (1) WO2012148003A1 (OSRAM)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2173379T1 (sl) 2007-07-02 2015-12-31 Oncomed Pharmaceuticals, Inc. Sestavki in postopki za zdravljenje in diagnosticiranje raka
HUE054211T2 (hu) * 2011-04-28 2021-08-30 Sbi Biotech Co Ltd Humán receptor típusú fehérje-tirozin-foszfatáz elleni antitest
MX349198B (es) 2011-07-15 2017-07-18 Oncomed Pharmaceuticals Inc * Agentes que se unen a las proteinas de r-espondinas (rspo) y usos de los mismos.
WO2014012007A2 (en) * 2012-07-13 2014-01-16 Oncomed Pharmaceuticals, Inc. Rspo3 binding agents and uses thereof
US20150175979A1 (en) 2012-07-23 2015-06-25 La Jolla Institute For Allergy And Immunology Ptprs and proteoglycans in autoimmune disease
AU2015213481A1 (en) * 2014-02-04 2016-08-25 Ludwig Institute For Cancer Research Ltd Anti-Metalloprotease antibody for diagnosis and treatment of cancers
US11160873B2 (en) * 2014-02-04 2021-11-02 Monash University Anti-metalloprotease antibody for diagnosis and treatment of cancers
EP3193935A4 (en) 2014-09-16 2018-03-21 Oncomed Pharmaceuticals, Inc. Treatment of fibrotic diseases
CN107002114A (zh) * 2014-12-18 2017-08-01 豪夫迈·罗氏有限公司 用于确定cdc引发抗体的测定试验和方法
EP3600421A4 (en) * 2017-03-23 2021-01-06 The Trustees of The University of Pennsylvania ANTI-C5A ANTIBODIES AND USES OF THEM
JP2020514394A (ja) * 2017-03-24 2020-05-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 異常な線維芽細胞におけるプロテオグリカンの不規則性及びそれに基づく治療法
WO2019028182A2 (en) * 2017-08-01 2019-02-07 Remd Biotherapeutics, Inc. TREATMENT OF CANCER USING ANTIBODIES BINDING TO THE HUMAN CD134 RECEPTOR (OX40)
US12054543B2 (en) 2018-07-25 2024-08-06 Accurus Biosciences, Inc. CLDN 18.2-specific monoclonal antibodies and methods of use thereof
GB201910899D0 (en) * 2019-07-31 2019-09-11 Scancell Ltd Binding members
AU2020357889A1 (en) * 2019-10-04 2022-03-24 Albert Einstein College Of Medicine KIR3DL3 is an inhibitory receptor of the immune system and uses thereof
AU2022317144A1 (en) 2021-07-30 2024-01-25 The Regents Of The University Of California Ptprs in autoimmunity
CN114426582B (zh) * 2022-01-07 2022-11-25 陕西脉元生物科技有限公司 一种神经特异性烯醇化酶单克隆抗体及其制备方法和应用
CN116041526B (zh) * 2022-11-14 2023-09-29 华中农业大学 一种鼠抗草鱼IgT单克隆抗体及其制备方法和应用
WO2024124164A2 (en) * 2022-12-09 2024-06-13 The Trustees Of The University Of Pennsylvania Compositions and methods for delivery of immunostimulatory cytokines to chimeric antigen receptor immune cells
WO2024186740A2 (en) * 2023-03-03 2024-09-12 Case Western Reserve University Cell adhesion molecule targeted immunotherapies
CN118994384B (zh) * 2024-08-09 2025-09-26 陕西脉元生物科技有限公司 抗Ri的人源化单克隆抗体及其应用和基于其的检测方法
CN119874900B (zh) * 2025-03-06 2025-10-17 吉林大学 一种单克隆抗体及其在制备治疗肿瘤药物中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009656A1 (en) 1993-10-01 1995-04-13 New York University Novel receptor-type phosphotyrosine phosphatase-sigma
AU2003252328A1 (en) 2002-08-01 2004-02-23 Ginkgo Biomedical Research Institute Co., Ltd. Method of detecting mouse interferon-producing cells
WO2004081047A1 (ja) * 2003-03-14 2004-09-23 Taisho Pharmaceutical Co., Ltd. モノクローナル抗体及びこれを産生するハイブリドーマ
JP2007530679A (ja) 2004-03-27 2007-11-01 ジ・アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ザ・ユニバーシティー・オブ・アリゾナ 癌治療のための組成物および方法
US20080008719A1 (en) 2004-07-10 2008-01-10 Bowdish Katherine S Methods and compositions for the treatment of prostate cancer
EP1928916A2 (en) * 2005-09-29 2008-06-11 Viral Logic Systems Technology Corp. Immunomodulatory compositions and uses therefor
WO2009003274A1 (en) * 2007-06-29 2009-01-08 The Hospital For Sick Children Susceptibility gene for inflammatory bowel disease
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WO2011022462A2 (en) * 2009-08-18 2011-02-24 President And Fellows Of Harvard College Neural regeneration
WO2011097327A2 (en) * 2010-02-02 2011-08-11 La Jolla Institute For Allergy & Immunology Compositions and methods of modulating receptor protein tyrosine phosphatases
HUE054211T2 (hu) * 2011-04-28 2021-08-30 Sbi Biotech Co Ltd Humán receptor típusú fehérje-tirozin-foszfatáz elleni antitest

Also Published As

Publication number Publication date
PT2702412T (pt) 2017-11-02
MX352599B (es) 2017-11-30
SG10201503257WA (en) 2015-06-29
RU2017118262A3 (OSRAM) 2018-11-02
RU2715642C2 (ru) 2020-03-02
EP3232202B1 (en) 2020-02-19
JP6412072B2 (ja) 2018-10-24
JP6001557B2 (ja) 2016-10-05
CA2834243A1 (en) 2012-11-01
SG194614A1 (en) 2013-12-30
AU2016262677B2 (en) 2018-08-30
KR101873614B1 (ko) 2018-07-02
ES2638088T3 (es) 2017-10-18
JP2017048183A (ja) 2017-03-09
US9803026B2 (en) 2017-10-31
PL3232202T3 (pl) 2020-10-05
RU2013152816A (ru) 2015-06-10
US20140127223A1 (en) 2014-05-08
US10730955B2 (en) 2020-08-04
IL229127A0 (en) 2013-12-31
US20180155446A1 (en) 2018-06-07
PT3232202T (pt) 2020-05-22
CN103703372A (zh) 2014-04-02
AU2012248158B2 (en) 2016-09-08
AU2012248158C1 (en) 2017-02-02
MX2013012393A (es) 2014-04-30
WO2012148003A1 (en) 2012-11-01
HUE054211T2 (hu) 2021-08-30
ES2788183T3 (es) 2020-10-20
AU2016262677A1 (en) 2016-12-08
CA2834243C (en) 2019-08-27
CN103703372B (zh) 2018-01-26
JP2014524733A (ja) 2014-09-25
IL229127A (en) 2017-11-30
EP2702412B1 (en) 2017-07-26
PL2702412T3 (pl) 2018-01-31
EP2702412A1 (en) 2014-03-05
KR20140033024A (ko) 2014-03-17
EP3232202A1 (en) 2017-10-18
RU2017118262A (ru) 2018-11-02
SG10202108240VA (en) 2021-09-29
AU2012248158A1 (en) 2014-01-30
BR112013027631A2 (pt) 2022-01-04

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