HUE034667T2 - Tiotrópium-tartalmú összetételt magában foglaló inhalátor - Google Patents

Tiotrópium-tartalmú összetételt magában foglaló inhalátor Download PDF

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Publication number
HUE034667T2
HUE034667T2 HUE12805442A HUE12805442A HUE034667T2 HU E034667 T2 HUE034667 T2 HU E034667T2 HU E12805442 A HUE12805442 A HU E12805442A HU E12805442 A HUE12805442 A HU E12805442A HU E034667 T2 HUE034667 T2 HU E034667T2
Authority
HU
Hungary
Prior art keywords
inhaler
hfa
tiotropium
composition
valve
Prior art date
Application number
HUE12805442A
Other languages
English (en)
Inventor
Xian Ming Zeng
Derek Fenlon
Original Assignee
Teva Branded Pharmaceutical Prod R & D Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45788842&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE034667(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Branded Pharmaceutical Prod R & D Inc filed Critical Teva Branded Pharmaceutical Prod R & D Inc
Publication of HUE034667T2 publication Critical patent/HUE034667T2/hu

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0095—Preventing manual activation in absence of inhalation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Claims (2)

  1. iliÂ#îURf~TâRmMù OSRrrémT hagàs^ phalátor iSIliADAkNl ÏGêtiYFObTOK %, Túlnyomásos, kimért dózisé inhalátor, amely magában foglal egy tartályt, amely tartály egy tiotróplum sót, egy szerves savat, agy első segidntdőszect és HFA hajtógázt magában foglaló öídatkészítményt tartalmas, és amely inhalátor egy beleg zissai működtetett Inhalátor.
  2. 2, Az t. igénypont szerinti inhalátor, amelyben a tiotróplom só tiotréplum-bromld, S« il:l, «|y a 2, igénypont Szerinti inhalátor, amelyben a HFA hajtógáz HFA Í34a és/vagy HFA 327, #,. A2 1- igénypont szerinti mhalétör, amelyben az nfdatkészítmény magában foglal további agy második segéd oldószert, a mai ynak forráspontfa magasabb, mint ez első sag édo ki őszem e k, S, Az .1, vagy a 4, igénypont szerinti inhalátor, amelyben az old at készítmény agy tiotróplum sót, etanolt, vizet, citromsavat, HFA :134a-4 és adott esetben glicerint foglal magában, #, Az előző ifénypontpk bármelyike szerinti inhalátor, ameSy inhalátor magában fbglal egy rugalmasén deformálható elemet (460), amely a tartály (2.5) belső szelepének (40) működtetésére képes eíőterbeíist fejt ki a készítmény kimért dózisának a tartályból pl) veié kiengedése báljából, egy szebkezétei (440, 4$S, 540), amely az aeroszol szalag (40) működtetését megakadályozni képes ellenálló prmmsflkus erét fejt ki, valamint egy, az ellenálló pneumatikus em felszabadítására képes, heíégzéssei működtetett kioldó eszközt (S4ö), amely lehetővé teszi, hogy az aleterbeles működtesse az aeroszol szelepet (40), is lehetővé teszi a készítmény kimért dozissrÄ kijuttatását
HUE12805442A 2011-12-19 2012-12-12 Tiotrópium-tartalmú összetételt magában foglaló inhalátor HUE034667T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161577314P 2011-12-19 2011-12-19
GB201200504A GB201200504D0 (en) 2011-12-19 2012-01-13 An inhaler

Publications (1)

Publication Number Publication Date
HUE034667T2 true HUE034667T2 (hu) 2018-02-28

Family

ID=45788842

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE12805442A HUE034667T2 (hu) 2011-12-19 2012-12-12 Tiotrópium-tartalmú összetételt magában foglaló inhalátor
HUE12196726A HUE030015T2 (hu) 2011-12-19 2012-12-12 Tiotrópium-tartalmú összetételt magában foglaló inhalátor

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE12196726A HUE030015T2 (hu) 2011-12-19 2012-12-12 Tiotrópium-tartalmú összetételt magában foglaló inhalátor

Country Status (22)

Country Link
US (1) US20140373832A1 (hu)
EP (2) EP2800567B1 (hu)
JP (1) JP2015502220A (hu)
KR (2) KR101629119B1 (hu)
CN (1) CN104010640A (hu)
AR (1) AR089597A1 (hu)
AU (1) AU2012358128B2 (hu)
BR (1) BR112014014536A2 (hu)
CA (1) CA2856054C (hu)
DK (2) DK2606892T3 (hu)
EA (1) EA029047B1 (hu)
ES (2) ES2644572T3 (hu)
GB (1) GB201200504D0 (hu)
HK (2) HK1200117A1 (hu)
HU (2) HUE034667T2 (hu)
IL (1) IL232945B (hu)
MX (1) MX357619B (hu)
PL (2) PL2606892T3 (hu)
TW (1) TWI524905B (hu)
UY (1) UY34526A (hu)
WO (1) WO2013092345A1 (hu)
ZA (1) ZA201403042B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201200525D0 (en) 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
WO2013127738A1 (de) * 2012-02-28 2013-09-06 Boehringer Ingelheim International Gmbh Neue treibgashaltige tiotropium-formulierung
US9636425B2 (en) * 2012-09-18 2017-05-02 Focal Point Technologies, Llc Method of dry dye delivery for staining the eye
US10034866B2 (en) 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
WO2017075018A1 (en) * 2015-10-29 2017-05-04 3M Innovative Properties Company Formulation and aerosol canisters, inhalers, and the like containing the formulation
WO2017112476A2 (en) 2015-12-21 2017-06-29 3M Innovative Properties Company Dose release firing systems and medicinal inhalers comprising same
WO2017112451A1 (en) * 2015-12-21 2017-06-29 3M Innovative Properties Company Auto-reset dose release firing systems, medicinal inhalers comprising same, and methods of using same
GB2553534A (en) * 2016-09-07 2018-03-14 3M Innovative Properties Co Trigger mechanism for an inhaler
GB2553535A (en) * 2016-09-07 2018-03-14 3M Innovative Properties Co Trigger mechansim for an inhaler
GB201702408D0 (en) 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods
GB201702407D0 (en) 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods
EP3813797A4 (en) * 2018-06-27 2022-03-30 Kindeva Drug Delivery L.P. TIOTROPIUM FORMULATION AND INHALER
FR3089127B1 (fr) * 2018-11-30 2020-11-20 Aptar France Sas Dispositif de distribution de produit fluide synchronisé avec l'inhalation

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
GB9026191D0 (en) 1990-12-01 1991-01-16 Harris Pharma Ltd Breath actuated dispensing device
GB2264238A (en) 1992-05-29 1993-08-25 Norton Healthcare Ltd Medicament inhalor device
WO1994013263A1 (en) 1992-12-09 1994-06-23 Jager Paul D Stabilized medicinal aerosol solution formulations
HU230804B1 (hu) * 2000-05-22 2018-06-28 Chiesi Farmaceutici S.P.A Gyógyászati célú stabil aeroszol összetétel, inhalátor az aeroszol pontos adagolásához és eljárás ennek feltöltésére
US6553988B1 (en) * 2000-06-09 2003-04-29 Norton Healthcare, Inc. Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber
DE10214263A1 (de) * 2002-03-28 2003-10-16 Boehringer Ingelheim Pharma HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum
US7311894B2 (en) * 2002-03-28 2007-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations containing an anticholinergic
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MXPA05006383A (es) * 2002-12-16 2005-08-29 Boehringer Ingelheim Pharma Formulaciones de soluciones de hidrofluorocarburo que contienen tiotropio.
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Also Published As

Publication number Publication date
US20140373832A1 (en) 2014-12-25
CA2856054A1 (en) 2013-06-27
HK1200341A1 (en) 2015-08-07
ES2644572T3 (es) 2017-11-29
MX357619B (es) 2018-07-17
EP2800567B1 (en) 2017-09-27
JP2015502220A (ja) 2015-01-22
IL232945B (en) 2018-05-31
NZ711668A (en) 2017-01-27
DK2800567T3 (da) 2017-11-06
GB201200504D0 (en) 2012-02-22
EP2800567A1 (en) 2014-11-12
WO2013092345A1 (en) 2013-06-27
TW201341000A (zh) 2013-10-16
IL232945A0 (en) 2014-07-31
KR101629119B1 (ko) 2016-06-09
ES2593281T3 (es) 2016-12-07
PL2606892T3 (pl) 2017-02-28
CN104010640A (zh) 2014-08-27
AR089597A1 (es) 2014-09-03
HK1200117A1 (en) 2015-07-31
KR20150118195A (ko) 2015-10-21
ZA201403042B (en) 2016-08-31
EA029047B1 (ru) 2018-02-28
NZ624160A (en) 2016-05-27
KR20140096159A (ko) 2014-08-04
PL2800567T3 (pl) 2018-04-30
BR112014014536A2 (pt) 2017-06-13
HUE030015T2 (hu) 2017-04-28
DK2606892T3 (en) 2016-09-26
UY34526A (es) 2014-07-31
MX2014007358A (es) 2014-11-21
TWI524905B (zh) 2016-03-11
AU2012358128B2 (en) 2015-09-17
CA2856054C (en) 2016-11-22
EP2606892A1 (en) 2013-06-26
EP2606892B1 (en) 2016-08-24
EA201491205A1 (ru) 2014-10-30
AU2012358128A1 (en) 2014-05-22

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