HUE025076T2 - New isolated and purified Chikungunya virus strains and polynucleotides and polypeptide sequences, their diagnostic and immunogenic applications - Google Patents

New isolated and purified Chikungunya virus strains and polynucleotides and polypeptide sequences, their diagnostic and immunogenic applications Download PDF

Info

Publication number
HUE025076T2
HUE025076T2 HUE07734896A HUE07734896A HUE025076T2 HU E025076 T2 HUE025076 T2 HU E025076T2 HU E07734896 A HUE07734896 A HU E07734896A HU E07734896 A HUE07734896 A HU E07734896A HU E025076 T2 HUE025076 T2 HU E025076T2
Authority
HU
Hungary
Prior art keywords
fragment
virus
chik
strain
sequence
Prior art date
Application number
HUE07734896A
Other languages
English (en)
Hungarian (hu)
Inventor
Philippe Despres
Anne-Claire Brehin
Valerie Marechal
Pierre Charneau
Philippe Souque
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002538898A external-priority patent/CA2538898A1/fr
Application filed by Pasteur Institut filed Critical Pasteur Institut
Publication of HUE025076T2 publication Critical patent/HUE025076T2/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/36011Togaviridae
    • C12N2770/36111Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36121Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/36011Togaviridae
    • C12N2770/36111Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/36011Togaviridae
    • C12N2770/36111Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36131Uses of virus other than therapeutic or vaccine, e.g. disinfectant
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/18Togaviridae; Flaviviridae
    • G01N2333/181Alphaviruses or Group A arboviruses, e.g. sindbis, VEE, EEE, WEE or semliki forest virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
HUE07734896A 2006-03-15 2007-03-15 New isolated and purified Chikungunya virus strains and polynucleotides and polypeptide sequences, their diagnostic and immunogenic applications HUE025076T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002538898A CA2538898A1 (fr) 2006-03-15 2006-03-15 Nouvelles souches isolees et purifiees du virus chikungunya et sequences nucleotidiques et peptidiques, applications diagnostiques et immunogeniques
CA 2545597 CA2545597A1 (en) 2006-03-15 2006-04-04 Novel isolated and purified strains of chikungunya virus and polynucleotides and polypeptides sequences, diagnostic and immunogenical uses thereof

Publications (1)

Publication Number Publication Date
HUE025076T2 true HUE025076T2 (en) 2016-02-29

Family

ID=38481184

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE07734896A HUE025076T2 (en) 2006-03-15 2007-03-15 New isolated and purified Chikungunya virus strains and polynucleotides and polypeptide sequences, their diagnostic and immunogenic applications

Country Status (12)

Country Link
US (2) US20100055105A1 (enExample)
EP (2) EP2001900B1 (enExample)
JP (2) JP5923232B2 (enExample)
AU (1) AU2007226231B2 (enExample)
CA (2) CA2545597A1 (enExample)
DK (1) DK2001900T3 (enExample)
ES (1) ES2543839T3 (enExample)
HU (1) HUE025076T2 (enExample)
PL (1) PL2001900T3 (enExample)
PT (1) PT2001900E (enExample)
SI (1) SI2001900T1 (enExample)
WO (1) WO2007105111A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2545597A1 (en) * 2006-03-15 2007-09-15 Institut Pasteur Novel isolated and purified strains of chikungunya virus and polynucleotides and polypeptides sequences, diagnostic and immunogenical uses thereof
EP2073839B1 (en) * 2006-09-01 2016-10-19 Bharat Biotech International Limited A vaccine for chikungunya virus infection
CA2598966A1 (en) * 2007-09-07 2009-03-07 Institut Pasteur Anti-chikungunya monoclonal antibodies and uses thereof
FR2921064A1 (fr) * 2007-09-14 2009-03-20 Biomerieux Sa Oligonucleotides, utilisation, methode de detection et kit permettant de diagnostiquer la presence du gene e1 du virus du chikungunya
JP5744719B2 (ja) * 2008-04-04 2015-07-08 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア チクングニヤウィルスタンパク質の共通配列、これをコードする核酸分子、並びにこれを使用する組成物および方法
EP2808405B1 (en) 2008-04-21 2018-06-06 Gen-Probe Incorporated Method for Detecting Chikungunya Virus
JP2012518431A (ja) * 2009-02-25 2012-08-16 ビッグテック プライベート リミテッド チクングニア検出用のプローブおよびプライマー
CN103476788A (zh) * 2010-12-10 2013-12-25 新加坡科技研究局 免疫原性屈曲病毒肽
WO2012131580A1 (en) * 2011-03-28 2012-10-04 Scms, Institute Of Bioscience And Biotechnology Research And Development Method of detecting chikungunya virus utilizing a recombinant el coat peptide antigen
EP2712871A1 (en) 2012-09-27 2014-04-02 Institut Pasteur Recombinant Measles virus expressing Chikungunya virus polypeptides and their applications
US9701719B2 (en) 2012-09-27 2017-07-11 Research Development Foundation Attenuated Chikungunya virus
US11104916B2 (en) 2016-07-15 2021-08-31 Etubics Corporation Compositions and methods for alphavirus vaccination
TW202300515A (zh) 2016-10-20 2023-01-01 法商賽諾菲公司 抗chikv抗體及其用途
KR102757369B1 (ko) * 2017-09-21 2025-01-20 발네바 에스이 면역원성 치쿤구니야 바이러스 chikv-델타5nsp3을 포함하는 약제학적 조성물의 생산 방법
WO2020069054A1 (en) * 2018-09-27 2020-04-02 Texas Tech University System Stable cell line secreting chikungunya virus (chikv) virus like particles (vlp) for vaccines
PH12023550246A1 (en) * 2020-07-31 2024-06-24 Replicate Bioscience Inc Modified chikungunya viruses and sindbis viruses and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1922084A4 (en) * 2005-08-11 2011-01-12 Univ Texas INFECTIOUS CLONING OF CHICUNGUNYA VIRUS AND ITS USE
CA2545597A1 (en) * 2006-03-15 2007-09-15 Institut Pasteur Novel isolated and purified strains of chikungunya virus and polynucleotides and polypeptides sequences, diagnostic and immunogenical uses thereof
EP2073839B1 (en) * 2006-09-01 2016-10-19 Bharat Biotech International Limited A vaccine for chikungunya virus infection

Also Published As

Publication number Publication date
JP2009529868A (ja) 2009-08-27
ES2543839T3 (es) 2015-08-24
PL2001900T3 (pl) 2015-10-30
AU2007226231A1 (en) 2007-09-20
US20100055105A1 (en) 2010-03-04
PT2001900E (pt) 2015-09-15
JP5923232B2 (ja) 2016-05-24
CA2646520A1 (en) 2007-09-20
WO2007105111A3 (en) 2008-03-27
EP2001900B1 (en) 2015-04-29
JP2013126414A (ja) 2013-06-27
SI2001900T1 (sl) 2015-09-30
EP2001900A2 (en) 2008-12-17
JP6104584B2 (ja) 2017-03-29
WO2007105111A2 (en) 2007-09-20
DK2001900T3 (en) 2015-07-27
EP2460822A2 (en) 2012-06-06
AU2007226231B2 (en) 2013-07-11
CA2646520C (en) 2018-05-15
US20150111197A1 (en) 2015-04-23
US9442114B2 (en) 2016-09-13
EP2460822A3 (en) 2012-09-26
CA2545597A1 (en) 2007-09-15

Similar Documents

Publication Publication Date Title
DK2001900T3 (en) HIS UNKNOWN ISOLATED AND PURIFIED STORES OF CHIKUNGUNYA VIRUS AND POLYNUCLEOTIDE AND POLYPEPTIME SEQUENCES, DIAGNOSTIC AND IMMUNOGENIC APPLICATIONS THEREOF
Schuffenecker et al. Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak
Hsu et al. Artificial mutations and natural variations in the CD46 molecules from human and monkey cells define regions important for measles virus binding
Kofler et al. Capsid protein C of tick-borne encephalitis virus tolerates large internal deletions and is a favorable target for attenuation of virulence
JP5054384B2 (ja) Sars関連コロナウイルスの新規系統及びその利用
EP2197912B1 (en) Anti-chikungunya monoclonal antibodies and uses thereof
EP2504358B1 (en) T cell receptors specific for immunodominant ctl epitopes of hcv
NZ267838A (en) Preparation of an hiv gp 120 subunit vaccine involving determining a neutralising epitope in the v2 and/or c4 domains
EP2959915A1 (en) A dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection
Matsuyama et al. Communication between S1N330 and a region in S2 of murine coronavirus spike protein is important for virus entry into cells expressing CEACAM1b receptor
Hobman et al. Analysis of rubella virus E1 glycosylation mutants expressed in COS cells
Heinz et al. Monoclonal antibodies to the structural glycoprotein of tick-borne encephalitis virus
CA2579507C (en) Novel isolated and purified strains of chikungunya virus and polynucleotides and polypeptides sequences, diagnostic and immunogenical uses thereof
CN113248608A (zh) 一种基孔肯雅病毒e2蛋白兔单克隆抗体及其用途
JP5290576B2 (ja) 修飾されたhiv−1エンベロープタンパク質
EP0997529B1 (en) Feline immunodeficiency virus strain FIV-141 and uses thereof
Myrmel et al. Antigenic diversity of Norwalk-like viruses: expression of the capsid protein of a genogroup I virus, distantly related to Norwalk virus
Azarm The Functional and Antigenic Diversity of the Henipavirus Glycoproteins
AU2023362558A1 (en) Polynucleotides and lentiviral vectors expressing non-structural antigens of a flavivirus selected from the group of denv, zikv and yfv, inducing protective cd8+ t-cell immunity in a host
Messera et al. Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity
CA2483870A1 (en) Interacting site for gp41 on gp120 of hiv-1