HU9300458D0 - 4-amino-2-ureido-pyrimidine-5-carboxylic acid amide derivatives and method for producing them - Google Patents

4-amino-2-ureido-pyrimidine-5-carboxylic acid amide derivatives and method for producing them

Info

Publication number
HU9300458D0
HU9300458D0 HU9300458A HU9300458A HU9300458D0 HU 9300458 D0 HU9300458 D0 HU 9300458D0 HU 9300458 A HU9300458 A HU 9300458A HU 9300458 A HU9300458 A HU 9300458A HU 9300458 D0 HU9300458 D0 HU 9300458D0
Authority
HU
Hungary
Prior art keywords
ureido
pyrimidine
amino
producing
carboxylic acid
Prior art date
Application number
HU9300458A
Other languages
English (en)
Other versions
HU213212B (en
HUT63409A (en
Inventor
Klaus-Dieter Kampe
Ernold Granzer
Michael Leineweber
Gerhard Rackur
Hans Georg Boeger
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HU9300458D0 publication Critical patent/HU9300458D0/hu
Publication of HUT63409A publication Critical patent/HUT63409A/hu
Priority to HU9501122A priority Critical patent/HUT70638A/hu
Publication of HU213212B publication Critical patent/HU213212B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HU9300458A 1992-02-22 1993-02-19 Process for producing acid additional salts of 4-amino-2-ureidopyrimidine-5-carboxylic acid amide derivatives and pharmaceutical compositions comprising the same HU213212B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU9501122A HUT70638A (en) 1992-02-22 1995-04-20 Substituted guanidine derivatives and process for producing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4205484 1992-02-22

Publications (3)

Publication Number Publication Date
HU9300458D0 true HU9300458D0 (en) 1993-05-28
HUT63409A HUT63409A (en) 1993-08-30
HU213212B HU213212B (en) 1997-03-28

Family

ID=6452364

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9300458A HU213212B (en) 1992-02-22 1993-02-19 Process for producing acid additional salts of 4-amino-2-ureidopyrimidine-5-carboxylic acid amide derivatives and pharmaceutical compositions comprising the same
HU9501122A HUT70638A (en) 1992-02-22 1995-04-20 Substituted guanidine derivatives and process for producing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU9501122A HUT70638A (en) 1992-02-22 1995-04-20 Substituted guanidine derivatives and process for producing them

Country Status (16)

Country Link
US (1) US5571816A (hu)
EP (1) EP0557879B1 (hu)
JP (1) JP2726790B2 (hu)
AT (1) ATE147384T1 (hu)
AU (2) AU658266B2 (hu)
CA (1) CA2089954C (hu)
DE (1) DE59305012D1 (hu)
DK (1) DK0557879T3 (hu)
ES (1) ES2098570T3 (hu)
FI (1) FI105029B (hu)
GR (1) GR3022889T3 (hu)
HU (2) HU213212B (hu)
IL (1) IL104791A (hu)
NO (1) NO301589B1 (hu)
NZ (2) NZ264752A (hu)
ZA (1) ZA931182B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0557877T3 (da) * 1992-02-22 1998-04-27 Hoechst Ag Opløselige salte af 4-amino-2-(4,4-dimethyl-imidazolidin-2-on-l-yl)-pyrimidin-5-carboxylsyre-eN-methyl-N-(3-trifluormethyl-phenyl)-amide,fremgangsmådetil deres fremstilling, deres anvendelse som lægemidler og udgangsprodukter
DE19625089A1 (de) * 1996-06-24 1998-01-02 Hoechst Ag 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE19625088A1 (de) * 1996-06-24 1998-01-02 Hoechst Ag 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
JPH10265464A (ja) * 1997-03-24 1998-10-06 Sumitomo Pharmaceut Co Ltd Ｌｄｌ受容体遺伝子発現増強剤
DK0869121T3 (da) * 1997-04-04 2004-09-20 Aventis Pharma Gmbh Hypolipidæmiske propanolaminderivater
DE19845405C2 (de) 1998-10-02 2000-07-13 Aventis Pharma Gmbh Arylsubstituierte Propanolaminderivate und deren Verwendung
DE19845403B4 (de) * 1998-10-02 2005-02-10 Aventis Pharma Deutschland Gmbh Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
EP1223170B1 (en) 1999-10-12 2005-12-28 Takeda Pharmaceutical Company Limited Pyrimidine-5-carboxamide compounds, process for producing the same and use thereof
KR100566188B1 (ko) * 1999-11-27 2006-03-29 동화약품공업주식회사 신규의 5-피리미딘카르복스아미드 유도체 및 그를포함하는 약학적 조성물
KR100566189B1 (ko) * 1999-12-29 2006-03-29 동화약품공업주식회사 신규의 5-피리미딘카르복스아미드 유도체 및 그를포함하는 약학적 조성물
JP5557832B2 (ja) * 2008-03-18 2014-07-23 メルク・シャープ・アンド・ドーム・コーポレーション 置換４−ヒドロキシピリジン−５−カルボキサミド
JP2011057661A (ja) * 2009-08-14 2011-03-24 Bayer Cropscience Ag 殺虫性カルボキサミド類

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853220A1 (de) * 1978-12-09 1980-07-03 Hoechst Ag Neue amino-pyrimidin-carbanilide, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
DE3522940A1 (de) * 1985-06-27 1987-01-08 Hoechst Ag 4-amino-2-(imidazolidin-2-on-1-yl)-pyrimidin-5-carbonsaeure-(n-(3-trifluormethyl-phenyl)-amide) zur antithrombotischen prophylaxe und behandlung sowie ihre verwendung zur herstellung von antithrombotisch wirksamen arzneimitteln
DK0557877T3 (da) * 1992-02-22 1998-04-27 Hoechst Ag Opløselige salte af 4-amino-2-(4,4-dimethyl-imidazolidin-2-on-l-yl)-pyrimidin-5-carboxylsyre-eN-methyl-N-(3-trifluormethyl-phenyl)-amide,fremgangsmådetil deres fremstilling, deres anvendelse som lægemidler og udgangsprodukter

Also Published As

Publication number Publication date
GR3022889T3 (en) 1997-06-30
FI105029B (fi) 2000-05-31
FI930717A0 (fi) 1993-02-18
ATE147384T1 (de) 1997-01-15
ES2098570T3 (es) 1997-05-01
JPH0641120A (ja) 1994-02-15
DE59305012D1 (de) 1997-02-20
CA2089954A1 (en) 1993-08-23
US5571816A (en) 1996-11-05
NO930596D0 (no) 1993-02-19
HU213212B (en) 1997-03-28
EP0557879B1 (de) 1997-01-08
NO930596L (no) 1993-08-23
AU3376293A (en) 1993-08-26
DK0557879T3 (da) 1997-06-16
AU669462B2 (en) 1996-06-06
IL104791A0 (en) 1993-06-10
HUT63409A (en) 1993-08-30
AU1029095A (en) 1995-04-06
EP0557879A1 (de) 1993-09-01
IL104791A (en) 1997-11-20
NO301589B1 (no) 1997-11-17
FI930717A (fi) 1993-08-23
JP2726790B2 (ja) 1998-03-11
CA2089954C (en) 2002-03-26
HU9501122D0 (en) 1995-06-28
AU658266B2 (en) 1995-04-06
HUT70638A (en) 1995-10-30
NZ264752A (en) 1995-10-26
ZA931182B (en) 1993-09-16
NZ245936A (en) 1995-10-26

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee