HU9300132D0 - Method for producing phosphono-alkene-purine derivatives and medical preparatives of anti-viral effect containing them - Google Patents
Method for producing phosphono-alkene-purine derivatives and medical preparatives of anti-viral effect containing themInfo
- Publication number
- HU9300132D0 HU9300132D0 HU9300132A HU13291A HU9300132D0 HU 9300132 D0 HU9300132 D0 HU 9300132D0 HU 9300132 A HU9300132 A HU 9300132A HU 13291 A HU13291 A HU 13291A HU 9300132 D0 HU9300132 D0 HU 9300132D0
- Authority
- HU
- Hungary
- Prior art keywords
- phosphono
- alkene
- producing
- purine derivatives
- effect containing
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909015865A GB9015865D0 (en) | 1990-07-19 | 1990-07-19 | Novel compounds |
| GB919110774A GB9110774D0 (en) | 1991-05-18 | 1991-05-18 | Pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU9300132D0 true HU9300132D0 (en) | 1993-04-28 |
Family
ID=26297352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9300132A HU9300132D0 (en) | 1990-07-19 | 1991-07-15 | Method for producing phosphono-alkene-purine derivatives and medical preparatives of anti-viral effect containing them |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5356886A (hu) |
| EP (1) | EP0539487A1 (hu) |
| JP (1) | JPH05509307A (hu) |
| AU (1) | AU653542B2 (hu) |
| CA (1) | CA2087446A1 (hu) |
| FI (1) | FI930192A (hu) |
| HU (1) | HU9300132D0 (hu) |
| IE (1) | IE912503A1 (hu) |
| NZ (1) | NZ238998A (hu) |
| PT (1) | PT98341A (hu) |
| WO (1) | WO1992001698A1 (hu) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0531597A1 (en) * | 1991-09-12 | 1993-03-17 | Merrell Dow Pharmaceuticals Inc. | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine |
| EP0618214A1 (en) * | 1993-04-01 | 1994-10-05 | Merrell Dow Pharmaceuticals Inc. | Unsaturated phosphonate derivatives of purines and pyrimidines |
| US5817647A (en) * | 1993-04-01 | 1998-10-06 | Merrell Pharmaceuticals Inc. | Unsaturated acetylene phosphonate derivatives of purines |
| JPH09506333A (ja) * | 1993-09-17 | 1997-06-24 | ギリアード サイエンシーズ，インコーポレイテッド | 治療化合物の投薬方法 |
| US5656745A (en) * | 1993-09-17 | 1997-08-12 | Gilead Sciences, Inc. | Nucleotide analogs |
| US5798340A (en) * | 1993-09-17 | 1998-08-25 | Gilead Sciences, Inc. | Nucleotide analogs |
| US5977061A (en) * | 1995-04-21 | 1999-11-02 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | N6 - substituted nucleotide analagues and their use |
| US5922695A (en) * | 1996-07-26 | 1999-07-13 | Gilead Sciences, Inc. | Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability |
| AU3540101A (en) * | 2000-01-07 | 2001-07-16 | Universitaire Instelling Antwerpen | Purine derivatives, process for their preparation and use thereof |
| IL159494A0 (en) * | 2001-06-29 | 2004-06-01 | Acad Of Science Czech Republic | 6-2'-(phosphonomethoxy) alkoxy pyrimidine derivatives having antiviral activity |
| US7247621B2 (en) * | 2002-04-30 | 2007-07-24 | Valeant Research & Development | Antiviral phosphonate compounds and methods therefor |
| AU2004206827A1 (en) | 2003-01-14 | 2004-08-05 | Gilead Sciences, Inc. | Compositions and methods for combination antiviral therapy |
| CA2527805C (en) | 2003-06-16 | 2012-08-21 | Institute Of Organic Chemistry And Biochemistry, Academy Of Sciences Of The Czech Republic | Pyrimidine compounds having phosphonate groups as antiviral nucleotide analogs |
| JP5242375B2 (ja) * | 2005-04-01 | 2013-07-24 | ザ レゲントス オブ ザ ユニバーシティ オブ カリフォルニア | ホスホノ−ペント−２−エン−１−イルヌクレオシド及び類似体 |
| TWI375560B (en) | 2005-06-13 | 2012-11-01 | Gilead Sciences Inc | Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same |
| TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
| CN100526315C (zh) | 2005-06-16 | 2009-08-12 | 浙江医药股份有限公司新昌制药厂 | N2-喹啉或异喹啉取代的嘌呤衍生物及其制备方法和其用途 |
| TWI444384B (zh) | 2008-02-20 | 2014-07-11 | Gilead Sciences Inc | 核苷酸類似物及其在治療惡性腫瘤上的用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1288098C (en) * | 1984-08-24 | 1991-08-27 | Richard L. Tolman | 4-(guanin-9-yl)butanals and their 3-oxa, 3-thia and 2-ene derivatives having antiviral and antitumor activity |
| GB8724765D0 (en) * | 1987-10-22 | 1987-11-25 | Beecham Group Plc | Process |
| SE8801729D0 (sv) * | 1988-05-06 | 1988-05-06 | Astra Ab | Purine derivatives for use in therapy |
| EP0353955A3 (en) * | 1988-08-02 | 1991-08-14 | Beecham Group Plc | Novel compounds |
| EP0405748A1 (en) * | 1989-05-30 | 1991-01-02 | Beecham Group p.l.c. | Phosphonoderivative of purine with antiviral activity |
| DE69110528T2 (de) * | 1990-04-20 | 1996-03-14 | Inst Of Organic Chemistry And | Chirale 2-(Phosphonomethoxy)propyl-Guanine als antivirale Agentien. |
-
1991
- 1991-07-15 JP JP3512555A patent/JPH05509307A/ja active Pending
- 1991-07-15 WO PCT/GB1991/001171 patent/WO1992001698A1/en not_active Application Discontinuation
- 1991-07-15 HU HU9300132A patent/HU9300132D0/hu unknown
- 1991-07-15 CA CA002087446A patent/CA2087446A1/en not_active Abandoned
- 1991-07-15 AU AU82399/91A patent/AU653542B2/en not_active Ceased
- 1991-07-15 EP EP91913625A patent/EP0539487A1/en not_active Withdrawn
- 1991-07-15 US US07/965,260 patent/US5356886A/en not_active Expired - Fee Related
- 1991-07-17 IE IE250391A patent/IE912503A1/en unknown
- 1991-07-17 NZ NZ238998A patent/NZ238998A/en unknown
- 1991-07-17 PT PT98341A patent/PT98341A/pt not_active Application Discontinuation
-
1993
- 1993-01-18 FI FI930192A patent/FI930192A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992001698A1 (en) | 1992-02-06 |
| AU653542B2 (en) | 1994-10-06 |
| JPH05509307A (ja) | 1993-12-22 |
| US5356886A (en) | 1994-10-18 |
| FI930192A0 (fi) | 1993-01-18 |
| EP0539487A1 (en) | 1993-05-05 |
| CA2087446A1 (en) | 1992-01-20 |
| PT98341A (pt) | 1992-05-29 |
| IE912503A1 (en) | 1992-01-29 |
| FI930192A (fi) | 1993-01-18 |
| NZ238998A (en) | 1993-11-25 |
| AU8239991A (en) | 1992-02-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HU911789D0 (en) | Process for producing derivatives of triazolo-triazine and pyrazolo-triazine | |
| HU9203204D0 (en) | Method for producing compounds of anti-endotoxine effect and medical prepartives containing such compounds | |
| PL291546A1 (en) | Method of obtaining novel taxole derivatives | |
| PL291463A1 (en) | Method of obtaining novel derivatives of 3-amidopyrazole | |
| HU9300132D0 (en) | Method for producing phosphono-alkene-purine derivatives and medical preparatives of anti-viral effect containing them | |
| HU911915D0 (en) | Process for the production of imidazole derivatives and medical preparations containing them | |
| GB9109117D0 (en) | Cigarette and method of making same | |
| PL278545A1 (en) | Method of obtaining novel derivatives of cyclobutylpurine and cyclobutylpyrimidine | |
| PL292669A1 (en) | Method of obtaining novel derivatives of -ketoacetamide | |
| PL288598A1 (en) | Method of obtaining novel derivatives of azaoxyindole | |
| PL291312A1 (en) | Method of obtaining acetamide derivatives | |
| PL291886A1 (en) | Method of obtaining derivatives of 2-aminopyrimidylocarbonamide-4 | |
| HU911443D0 (en) | Process for the production of medical preparations containing pravastaine and fibrinous-acid derivatives | |
| HU904978D0 (en) | Process for producing derivatives of benzopyrane and benzothiopyrane | |
| YU236989A (en) | Derivatives of 2-iminobenzothiazoline and process for obtaining thereof | |
| HUT50167A (en) | Process for production of derivatives of tetrasole and medical compositions containing them | |
| PL292087A1 (en) | Method of obtaining derivatives of 8-chloroquinolone | |
| HU9202176D0 (en) | Method for producing tertiary-butyl-phenyl-1-amino-4-hydroxi-butane derivatives and medical preparatives containing said compounds | |
| HU9203720D0 (en) | Method for producing heterocyclic derivatives of anthracyclinole and anthracycline | |
| HU912213D0 (en) | Process for the production of amino-diol derivatives and medical preparations containing them | |
| HUT67274A (en) | Process for producing of tetrahydroindenoindoles and farmaceutical composition comprising them | |
| PL302373A1 (en) | Derivatives of substituted imidazobenzoxazin-1-one and method of obtaining them | |
| GR910100162A (en) | Method of producing alkanesulfonanilide derivatives | |
| HU9200230D0 (en) | Process for the production of 3-amino-sidnonimine derivatives and medical preparations containing them | |
| HUT50186A (en) | Process for production of derivatives of alpha-alkyl-penicillin and medical compositions containing them |