HU9202497D0 - Peptide derivatives - Google Patents
Peptide derivativesInfo
- Publication number
- HU9202497D0 HU9202497D0 HU922497Q HU249791Q HU9202497D0 HU 9202497 D0 HU9202497 D0 HU 9202497D0 HU 922497 Q HU922497 Q HU 922497Q HU 249791 Q HU249791 Q HU 249791Q HU 9202497 D0 HU9202497 D0 HU 9202497D0
- Authority
- HU
- Hungary
- Prior art keywords
- group
- alkyl
- amino
- alkenyl
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909026251A GB9026251D0 (en) | 1990-12-03 | 1990-12-03 | Netalloproteinase inhibitors |
GB919110339A GB9110339D0 (en) | 1991-05-13 | 1991-05-13 | Metalloproteinase inhibitors |
GB919110338A GB9110338D0 (en) | 1991-05-13 | 1991-05-13 | Metalloproteinase inhibitors |
GB919112901A GB9112901D0 (en) | 1991-06-14 | 1991-06-14 | Metalloproteinase inhibitors |
GB919112888A GB9112888D0 (en) | 1991-06-14 | 1991-06-14 | Metalloproteinase inhibitors |
GB919115039A GB9115039D0 (en) | 1991-07-11 | 1991-07-11 | Metalloproteinase inhibitors |
GB919115038A GB9115038D0 (en) | 1991-07-11 | 1991-07-11 | Metalloproteinase inhibitors |
GB919115916A GB9115916D0 (en) | 1991-07-23 | 1991-07-23 | Metalloproteinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
HU9202497D0 true HU9202497D0 (en) | 1992-10-28 |
Family
ID=27571285
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU922497A HUT62263A (en) | 1990-12-03 | 1991-12-03 | Process for producing peptidyl derivatives and pharmaceutical compositions comprising such compounds as active ingredient |
HU922497Q HU9202497D0 (en) | 1990-12-03 | 1991-12-03 | Peptide derivatives |
HU9202498A HUT61973A (en) | 1990-12-03 | 1991-12-03 | Process for producing peptidyl derivatives and pharmaceutical compositions comprising such compounds as active ingredient |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU922497A HUT62263A (en) | 1990-12-03 | 1991-12-03 | Process for producing peptidyl derivatives and pharmaceutical compositions comprising such compounds as active ingredient |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9202498A HUT61973A (en) | 1990-12-03 | 1991-12-03 | Process for producing peptidyl derivatives and pharmaceutical compositions comprising such compounds as active ingredient |
Country Status (16)
Country | Link |
---|---|
US (1) | US5300501A (hu) |
EP (2) | EP0489579B1 (hu) |
JP (2) | JPH05503719A (hu) |
KR (2) | KR927003521A (hu) |
AT (2) | ATE120451T1 (hu) |
AU (2) | AU652793B2 (hu) |
CA (2) | CA2073510A1 (hu) |
DE (2) | DE69108363T2 (hu) |
DK (1) | DK0489579T3 (hu) |
ES (1) | ES2069833T3 (hu) |
FI (2) | FI923494A (hu) |
GB (2) | GB2255340B (hu) |
GR (1) | GR3015567T3 (hu) |
HU (3) | HUT62263A (hu) |
NO (2) | NO922968L (hu) |
WO (2) | WO1992009565A1 (hu) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5892112A (en) * | 1990-11-21 | 1999-04-06 | Glycomed Incorporated | Process for preparing synthetic matrix metalloprotease inhibitors |
US5268384A (en) * | 1990-11-21 | 1993-12-07 | Galardy Richard E | Inhibition of angiogenesis by synthetic matrix metalloprotease inhibitors |
US5189178A (en) * | 1990-11-21 | 1993-02-23 | Galardy Richard E | Matrix metalloprotease inhibitors |
EP0520573A1 (en) * | 1991-06-27 | 1992-12-30 | Glaxo Inc. | Cyclic imide derivatives |
EP0634998B1 (en) * | 1992-04-07 | 1997-03-19 | British Biotech Pharmaceuticals Limited | Hydroxamic acid based collagenase and cytokine inhibitors |
GB9211707D0 (en) * | 1992-06-03 | 1992-07-15 | Celltech Ltd | Peptidyl derivatives |
GB9211706D0 (en) * | 1992-06-03 | 1992-07-15 | Celltech Ltd | Peptidyl derivatives |
AU666727B2 (en) * | 1992-06-25 | 1996-02-22 | F. Hoffmann-La Roche Ag | Hydroxamic acid derivatives |
US5326760A (en) * | 1992-06-29 | 1994-07-05 | Glaxo, Inc. | Aminobutanoic acid compounds having metalloprotease inhibiting properties |
WO1994007481A1 (en) * | 1992-10-02 | 1994-04-14 | Merck & Co., Inc. | N-(mercaptoacyl)peptidyl derivatives as antidegenerative agents |
US6090785A (en) * | 1992-10-15 | 2000-07-18 | Merck & Co., Inc. | Substituted N-carboxyalkylpeptidyl derivatives as antidegenerative agents |
GB9223904D0 (en) * | 1992-11-13 | 1993-01-06 | British Bio Technology | Inhibition of cytokine production |
EP0671911A4 (en) * | 1992-11-25 | 1996-08-21 | Merck & Co Inc | CARBOXY-PEPTIDYL DERIVATIVES FOR USE AS ACTIVE ANTI-DEGENERATIVE AGENTS. |
US5646167A (en) * | 1993-01-06 | 1997-07-08 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamix acids |
US5552419A (en) * | 1993-01-06 | 1996-09-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
US5455258A (en) * | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
US5506242A (en) * | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
US5652262A (en) * | 1993-03-16 | 1997-07-29 | British Biotech Pharmaceutical, Ltd. | Hydroxamic acid derivatives as metalloproteinase inhibitors |
AU6554294A (en) * | 1993-04-07 | 1994-10-24 | Glycomed Incorporated | Synthetic matrix metalloprotease inhibitors and uses thereof |
GB9307956D0 (en) * | 1993-04-17 | 1993-06-02 | Walls Alan J | Hydroxamic acid derivatives |
GB9308695D0 (en) * | 1993-04-27 | 1993-06-09 | Celltech Ltd | Peptidyl derivatives |
DE69419473T2 (de) * | 1993-04-27 | 2000-03-16 | Celltech Therapeutics Ltd | Peptidylderivate als inhibitoren von metalloproteinase |
EP0712390B1 (en) * | 1993-08-02 | 1998-12-09 | Celltech Therapeutics Limited | Succinamide derivatives, processes for their preparation and their use as gelatinase and collagenase inhibitors |
US5594106A (en) * | 1993-08-23 | 1997-01-14 | Immunex Corporation | Inhibitors of TNF-α secretion |
GB9320660D0 (en) * | 1993-10-07 | 1993-11-24 | British Bio Technology | Inhibition of cytokine production |
US6037472A (en) * | 1993-11-04 | 2000-03-14 | Syntex (U.S.A.) Inc. | Matrix metalloprotease inhibitors |
CN1049651C (zh) * | 1994-01-20 | 2000-02-23 | 英国生物技术药物有限公司 | 金属蛋白酶抑制剂 |
US5514716A (en) * | 1994-02-25 | 1996-05-07 | Sterling Winthrop, Inc. | Hydroxamic acid and carboxylic acid derivatives, process for their preparation and use thereof |
GB9501737D0 (en) * | 1994-04-25 | 1995-03-22 | Hoffmann La Roche | Hydroxamic acid derivatives |
AU2572295A (en) * | 1994-05-28 | 1995-12-21 | British Biotech Pharmaceuticals Limited | Succinyl hydroxamic acid, n-formyl-n-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors |
GB9411088D0 (en) * | 1994-06-03 | 1994-07-27 | Hoffmann La Roche | Hydroxylamine derivatives |
GB2303629B (en) * | 1994-06-22 | 1998-09-02 | British Biotech Pharm | Hydroxamic acids and their use as metalloproteinase inhibitors |
US5831004A (en) | 1994-10-27 | 1998-11-03 | Affymax Technologies N.V. | Inhibitors of metalloproteases, pharmaceutical compositions comprising same and methods of their use |
US5840698A (en) * | 1994-10-27 | 1998-11-24 | Affymax Technologies N.V. | Inhibitors of collagenase-1 and stormelysin-I metalloproteases, pharmaceutical compositions comprising same and methods of their use |
GB9423914D0 (en) * | 1994-11-26 | 1995-01-11 | British Biotech Pharm | Polyether derivatives as metalloproteinase inhibitors |
US5919940A (en) * | 1995-01-20 | 1999-07-06 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
US5857961A (en) * | 1995-06-07 | 1999-01-12 | Clarus Medical Systems, Inc. | Surgical instrument for use with a viewing system |
US5917090A (en) * | 1995-06-30 | 1999-06-29 | British Biotech Pharmaceuticals Ltd. | Matrix metalloproteinase inhibitors |
IT1277904B1 (it) * | 1995-08-07 | 1997-11-12 | Polifarma Spa | Metodo per determinare l'attivita' terapeutica di composti inibitori di metalloproteinasi, nuovi composti inibitori, e loro impiego |
US5665777A (en) * | 1995-11-14 | 1997-09-09 | Abbott Laboratories | Biphenyl hydroxamate inhibitors of matrix metalloproteinases |
JP2000500761A (ja) | 1995-11-23 | 2000-01-25 | ブリティッシュ バイオテック ファーマシューティカルズ リミテッド | 金属タンパク質分解酵素阻害剤 |
ES2195034T3 (es) * | 1995-12-08 | 2003-12-01 | Agouron Pharma | Inhibidor de metaloproteinasas, composicion farmaceutica que contiene este inhibidor y su utilizacion farmaceutica, y procedimientos que sirven para su preparacion. |
US6500948B1 (en) | 1995-12-08 | 2002-12-31 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors-compositions, uses preparation and intermediates thereof |
GB9613547D0 (en) * | 1996-06-27 | 1996-08-28 | Pharmacia Spa | Matrix metalloproteinase inhibitors |
US6462023B1 (en) | 1996-09-10 | 2002-10-08 | British Biotech Pharmaceuticals, Ltd. | Cytostatic agents |
ATE220660T1 (de) | 1996-09-10 | 2002-08-15 | British Biotech Pharm | Cytostatische hydroxamsäurederivate |
US6953788B1 (en) | 1996-09-19 | 2005-10-11 | Aventis Pharmaceuticals Inc. | 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase |
US6174915B1 (en) | 1997-03-25 | 2001-01-16 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
US6008243A (en) * | 1996-10-24 | 1999-12-28 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use |
JPH10130217A (ja) * | 1996-11-01 | 1998-05-19 | Kotobuki Seiyaku Kk | カルボン酸及びその誘導体及びその製造法並びにこれを含有する医薬組成物 |
ZA9818B (en) * | 1997-01-07 | 1998-07-02 | Abbott Lab | C-terminal ketone inhibitors of matrix metalloproteinases and tnf alpha secretion |
US5952320A (en) * | 1997-01-07 | 1999-09-14 | Abbott Laboratories | Macrocyclic inhibitors of matrix metalloproteinases and TNFα secretion |
US5985911A (en) * | 1997-01-07 | 1999-11-16 | Abbott Laboratories | C-terminal ketone inhibitors of matrix metalloproteinases and TNFα secretion |
US5985900A (en) * | 1997-04-01 | 1999-11-16 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
EP0887077A1 (de) * | 1997-06-27 | 1998-12-30 | Roche Diagnostics GmbH | Verwendung von Azulenderivaten als Metalloproteaseinhibitoren |
GB9803005D0 (en) | 1998-02-12 | 1998-04-08 | British Biotech Pharm | Anti-inflammatory agents |
GB9804504D0 (en) * | 1998-03-03 | 1998-04-29 | Leo Pharm Prod Ltd | Matrix metalloproteinase inhibitors |
US6288261B1 (en) | 1998-12-18 | 2001-09-11 | Abbott Laboratories | Inhibitors of matrix metalloproteinases |
JP2001031637A (ja) * | 1999-05-17 | 2001-02-06 | Fuji Chemical Industries Ltd | 新規なヒドロキサム酸誘導体 |
WO2000069812A1 (fr) * | 1999-05-17 | 2000-11-23 | Daiichi Fine Chemical Co., Ltd. | Nouveaux dérivés d'acide hydroxamique |
CO5210860A1 (es) | 1999-10-01 | 2002-10-30 | Hoffmann La Roche | Nuevos derivados de pirimidina-2,4,6-triona |
US6797820B2 (en) | 1999-12-17 | 2004-09-28 | Vicuron Pharmaceuticals Inc. | Succinate compounds, compositions and methods of use and preparation |
AU2001271068A1 (en) * | 2000-07-18 | 2002-01-30 | Chugai Seiyaku Kabushiki Kaisha | Matrix metalloprotease inhibitors |
US6716845B2 (en) | 2001-03-30 | 2004-04-06 | Hoffmann-La Roche Inc. | Barbituric acid derivatives |
AR036053A1 (es) | 2001-06-15 | 2004-08-04 | Versicor Inc | Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas |
DK1406893T3 (da) | 2001-06-15 | 2007-08-06 | Vicuron Pharm Inc | Bicykliske pyrrolidinforbindelser |
US7528227B2 (en) | 2004-03-23 | 2009-05-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Histone H2A peptide derivatives and uses thereof |
WO2005090387A2 (en) * | 2004-03-23 | 2005-09-29 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Histone h2a peptide derivatives and analogs and methods of use thereof |
US7605132B2 (en) | 2001-08-29 | 2009-10-20 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Protective factors against inflammation, burns and noxious stimuli |
WO2004060425A2 (en) * | 2002-12-27 | 2004-07-22 | Angiotech International Ag | Compositions and methods of using collagen and mmpi |
GB0818907D0 (en) * | 2008-10-15 | 2008-11-19 | Isis Innovation | Histone lysine demethylase inhibitors |
DE202010018378U1 (de) | 2009-04-10 | 2016-04-07 | Tufts Medical Center, Inc. | PAR-1-Aktivierung durch Metalloproteinase-1 (MMP-1) |
DE102014206916A1 (de) | 2014-04-10 | 2015-10-15 | Wacker Chemie Ag | Verfahren zur Ruthenium-katalysierten Umvinylierung von Carbonsäuren |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4743587A (en) * | 1985-09-10 | 1988-05-10 | G. D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
FR2609289B1 (fr) * | 1987-01-06 | 1991-03-29 | Bellon Labor Sa Roger | Nouveaux composes a activite d'inhibiteurs de collagenase, procede pour les preparer et compositions pharmaceutiques contenant ces composes |
GB8827308D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
CA2058797A1 (en) * | 1991-02-01 | 1992-08-02 | Michael John Broadhurst | Amino acid derivatives |
US5196412A (en) * | 1991-03-06 | 1993-03-23 | Johnson Matthey, Inc. | Gallium compounds |
-
1991
- 1991-12-03 KR KR1019920701788A patent/KR927003521A/ko not_active Application Discontinuation
- 1991-12-03 DE DE69108363T patent/DE69108363T2/de not_active Expired - Fee Related
- 1991-12-03 DE DE69108529T patent/DE69108529T2/de not_active Expired - Fee Related
- 1991-12-03 JP JP4500488A patent/JPH05503719A/ja active Pending
- 1991-12-03 HU HU922497A patent/HUT62263A/hu unknown
- 1991-12-03 AT AT91311254T patent/ATE120451T1/de not_active IP Right Cessation
- 1991-12-03 EP EP91311254A patent/EP0489579B1/en not_active Expired - Lifetime
- 1991-12-03 WO PCT/GB1991/002143 patent/WO1992009565A1/en active Application Filing
- 1991-12-03 KR KR1019920701787A patent/KR927003520A/ko not_active Application Discontinuation
- 1991-12-03 AT AT91311252T patent/ATE120182T1/de active
- 1991-12-03 CA CA002073510A patent/CA2073510A1/en not_active Abandoned
- 1991-12-03 ES ES91311254T patent/ES2069833T3/es not_active Expired - Lifetime
- 1991-12-03 DK DK91311254.6T patent/DK0489579T3/da active
- 1991-12-03 WO PCT/GB1991/002142 patent/WO1992009564A1/en active Application Filing
- 1991-12-03 JP JP4500489A patent/JPH05503720A/ja active Pending
- 1991-12-03 AU AU90173/91A patent/AU652793B2/en not_active Ceased
- 1991-12-03 US US07/916,108 patent/US5300501A/en not_active Expired - Lifetime
- 1991-12-03 HU HU922497Q patent/HU9202497D0/hu unknown
- 1991-12-03 CA CA002073513A patent/CA2073513A1/en not_active Abandoned
- 1991-12-03 AU AU90233/91A patent/AU652596B2/en not_active Ceased
- 1991-12-03 EP EP91311252A patent/EP0489577B1/en not_active Expired - Lifetime
- 1991-12-03 HU HU9202498A patent/HUT61973A/hu unknown
-
1992
- 1992-06-02 GB GB9211715A patent/GB2255340B/en not_active Expired - Fee Related
- 1992-06-02 GB GB9211714A patent/GB2255339B/en not_active Expired - Fee Related
- 1992-07-28 NO NO92922968A patent/NO922968L/no unknown
- 1992-07-28 NO NO92922967A patent/NO922967L/no unknown
- 1992-08-03 FI FI923494A patent/FI923494A/fi not_active Application Discontinuation
- 1992-08-03 FI FI923495A patent/FI923495A/fi not_active Application Discontinuation
-
1995
- 1995-03-30 GR GR940403917T patent/GR3015567T3/el unknown
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