HU908115D0 - Process for producing diazine derivatives and pharmaceutical preparatives containing these compounds - Google Patents
Process for producing diazine derivatives and pharmaceutical preparatives containing these compoundsInfo
- Publication number
- HU908115D0 HU908115D0 HU908115A HU811590A HU908115D0 HU 908115 D0 HU908115 D0 HU 908115D0 HU 908115 A HU908115 A HU 908115A HU 811590 A HU811590 A HU 811590A HU 908115 D0 HU908115 D0 HU 908115D0
- Authority
- HU
- Hungary
- Prior art keywords
- alkyl
- phenyl
- formula
- compounds
- substituents
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 125000005331 diazinyl group Chemical class N1=NC(=CC=C1)* 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000001424 substituent group Chemical group 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 230000009286 beneficial effect Effects 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- -1 oxy, thio, carbonyl Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000654 isopropylidene group Chemical group C(C)(C)=* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 210000001013 sinoatrial node Anatomy 0.000 abstract 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Vibration Prevention Devices (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Organic Insulating Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898929022A GB8929022D0 (en) | 1989-12-22 | 1989-12-22 | Diazine derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU908115D0 true HU908115D0 (en) | 1991-06-28 |
| HUT56087A HUT56087A (en) | 1991-07-29 |
| HU207511B HU207511B (en) | 1993-04-28 |
Family
ID=10668392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU908115A HU207511B (en) | 1989-12-22 | 1990-12-07 | Process for producing pirimidinium derivatives, nonionic formes of them and pharmaceutical compositions containing them |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5252567A (hu) |
| EP (1) | EP0434341B1 (hu) |
| JP (1) | JPH03291277A (hu) |
| KR (1) | KR910011838A (hu) |
| AT (1) | ATE122672T1 (hu) |
| AU (1) | AU641960B2 (hu) |
| CA (1) | CA2032743A1 (hu) |
| DE (1) | DE69019489T2 (hu) |
| DK (1) | DK0434341T3 (hu) |
| ES (1) | ES2072993T3 (hu) |
| FI (1) | FI906306A7 (hu) |
| GB (2) | GB8929022D0 (hu) |
| HU (1) | HU207511B (hu) |
| IE (1) | IE904391A1 (hu) |
| IL (1) | IL96609A0 (hu) |
| NO (1) | NO905378L (hu) |
| NZ (1) | NZ236417A (hu) |
| PT (1) | PT96315B (hu) |
| TW (1) | TW215088B (hu) |
| ZA (1) | ZA909852B (hu) |
| ZW (1) | ZW19290A1 (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9022644D0 (en) * | 1990-10-18 | 1990-11-28 | Ici Plc | Heterocyclic compounds |
| JP2007501781A (ja) * | 2003-08-07 | 2007-02-01 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 駆虫及び殺虫ピリミジン誘導体 |
| US7741976B2 (en) * | 2005-12-16 | 2010-06-22 | Hunt Power, L.P. | Server and method for processing meter data into a common format |
| SG11201700777VA (en) | 2014-08-04 | 2017-02-27 | Nuevolution As | Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases |
| US11447479B2 (en) | 2019-12-20 | 2022-09-20 | Nuevolution A/S | Compounds active towards nuclear receptors |
| TWI872177B (zh) | 2019-12-20 | 2025-02-11 | 丹麥商紐韋盧森公司 | 對核受體具有活性之化合物 |
| JP7713953B2 (ja) | 2020-03-31 | 2025-07-28 | ヌエヴォリューション・アクティーゼルスカブ | 核内受容体に対して活性な化合物 |
| CA3174176A1 (en) | 2020-03-31 | 2021-10-07 | Sanne Schroder Glad | Compounds active towards nuclear receptors |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB815833A (en) * | 1956-09-26 | 1959-07-01 | Boots Pure Drug Co Ltd | Phenanthridine compounds |
| BE492034A (hu) * | 1948-11-05 | |||
| DE1445740A1 (de) * | 1963-09-04 | 1968-11-28 | Bayer Ag | Verfahren zur Herstellung von Bispyrimidinium-Verbindungen |
| US4339453A (en) * | 1979-07-23 | 1982-07-13 | Merck & Co., Inc. | Antimicrobial aminopyrimidinium salts |
| US4287338A (en) * | 1980-03-10 | 1981-09-01 | The Upjohn Company | Sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide inner salts |
| FR2524467A1 (fr) * | 1982-03-30 | 1983-10-07 | Adir | Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant |
| US4503050A (en) * | 1983-06-02 | 1985-03-05 | Riker Laboratories, Inc. | Substituted imidazo[1,2-c]pyrimidines |
| US4725600A (en) * | 1984-07-13 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent |
| WO1987001706A2 (en) * | 1985-09-12 | 1987-03-26 | The Upjohn Company | C20 through c26 amino steroids |
| DE3703633A1 (de) * | 1986-02-14 | 1987-08-20 | Sandoz Ag | Purin-derivate, ihre herstellung und sie enthaltende arzneimittel |
| US4729995A (en) * | 1986-04-21 | 1988-03-08 | Toyo Boseki Kabushiki Kaisha | Pyrimidine 2,4-dioxamate compounds and pharmaceutical compositions |
| DE3629563A1 (de) * | 1986-08-02 | 1988-02-04 | Mildenberger & Willing Verpack | Tragbarer verpackungsbeutel aus kunststoffolie und verfahren zu dessen herstellung |
| DE3639563A1 (de) * | 1986-11-20 | 1988-06-01 | Basf Ag | N-arylsulfonyl-n'-pyrimidyl(triazinyl) -harnstoffe |
| HU206337B (en) * | 1988-12-29 | 1992-10-28 | Mitsui Petrochemical Ind | Process for producing pyrimidine derivatives and pharmaceutical compositions |
-
1989
- 1989-12-22 GB GB898929022A patent/GB8929022D0/en active Pending
-
1990
- 1990-11-28 GB GB909025810A patent/GB9025810D0/en active Pending
- 1990-12-05 IE IE439190A patent/IE904391A1/en unknown
- 1990-12-07 HU HU908115A patent/HU207511B/hu not_active IP Right Cessation
- 1990-12-07 ZA ZA909852A patent/ZA909852B/xx unknown
- 1990-12-09 IL IL96609A patent/IL96609A0/xx unknown
- 1990-12-10 NZ NZ236417A patent/NZ236417A/xx unknown
- 1990-12-10 AU AU67914/90A patent/AU641960B2/en not_active Ceased
- 1990-12-10 ZW ZW192/90A patent/ZW19290A1/xx unknown
- 1990-12-12 NO NO90905378A patent/NO905378L/no unknown
- 1990-12-17 ES ES90313772T patent/ES2072993T3/es not_active Expired - Lifetime
- 1990-12-17 DE DE69019489T patent/DE69019489T2/de not_active Expired - Fee Related
- 1990-12-17 AT AT90313772T patent/ATE122672T1/de not_active IP Right Cessation
- 1990-12-17 EP EP90313772A patent/EP0434341B1/en not_active Expired - Lifetime
- 1990-12-17 DK DK90313772.7T patent/DK0434341T3/da active
- 1990-12-18 US US07/629,502 patent/US5252567A/en not_active Expired - Fee Related
- 1990-12-19 CA CA002032743A patent/CA2032743A1/en not_active Abandoned
- 1990-12-20 FI FI906306A patent/FI906306A7/fi not_active Application Discontinuation
- 1990-12-21 KR KR1019900021264A patent/KR910011838A/ko not_active Withdrawn
- 1990-12-21 PT PT96315A patent/PT96315B/pt not_active IP Right Cessation
- 1990-12-21 JP JP2404924A patent/JPH03291277A/ja active Pending
- 1990-12-21 TW TW079110759A patent/TW215088B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0434341A1 (en) | 1991-06-26 |
| PT96315A (pt) | 1991-09-30 |
| CA2032743A1 (en) | 1991-06-23 |
| DK0434341T3 (da) | 1995-10-09 |
| TW215088B (hu) | 1993-10-21 |
| ZW19290A1 (en) | 1991-09-18 |
| AU6791490A (en) | 1991-06-27 |
| IE904391A1 (en) | 1991-07-03 |
| NO905378D0 (no) | 1990-12-12 |
| KR910011838A (ko) | 1991-08-07 |
| AU641960B2 (en) | 1993-10-07 |
| FI906306A0 (fi) | 1990-12-20 |
| ZA909852B (en) | 1991-10-30 |
| DE69019489T2 (de) | 1995-09-21 |
| NZ236417A (en) | 1994-04-27 |
| DE69019489D1 (de) | 1995-06-22 |
| JPH03291277A (ja) | 1991-12-20 |
| GB9025810D0 (en) | 1991-01-09 |
| FI906306A7 (fi) | 1991-06-23 |
| NO905378L (no) | 1991-06-24 |
| GB8929022D0 (en) | 1990-02-28 |
| HUT56087A (en) | 1991-07-29 |
| US5252567A (en) | 1993-10-12 |
| EP0434341B1 (en) | 1995-05-17 |
| PT96315B (pt) | 1998-06-30 |
| HU207511B (en) | 1993-04-28 |
| ATE122672T1 (de) | 1995-06-15 |
| IL96609A0 (en) | 1991-09-16 |
| ES2072993T3 (es) | 1995-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HMM4 | Cancellation of final prot. due to non-payment of fee |