HU205260B - Process for producing composition for diminishing weight - Google Patents

Abstract

Wt. reducing prepn. contains (all wt.%) either (a) 5-7 elder-flower, 4-6 juniper berries, 5-7 blood-wort, 5-7 nettle, 5-7 sweet fennel seeds, 5-7 dandelions root, 6-8 blackthorn flower, 5-7 coriander seed, 5-7 caraway-seed, 20-22 corn-silk 10-12 black alder-bark, 3-4 borage root 5-7 mustard seed, 5-7 field-pansy; or (b) 8-12 elder-flower, 8-12 blood-wort, 8-12 sweet-fennel, 8-12 caraway seed, 3-035 black-alder bark, 15-18 black-thorn, 8-12 corn-silk, 8-12 field pansy. - Ingredients (a) or (b) are ground to 1.5-2.2 dia. size, mixed and tabletted 2-5 pts. wt. hot water are added to make tees

Description

BACKGROUND OF THE INVENTION The present invention relates to a process for the preparation of a composition having a weight-reducing effect from a mixture of natural active substances and drugs known per se.

One of the symptoms of civilized society now becoming a people's disease is abnormal weight gain, obesity, which can be the cause of a number of serious illnesses such as diabetes mellitus, hypertension, arteriosclerosis and others. A major health problem is the restoration of ideal or at least normal weight to overweight individuals. Set.

In more severe cases, this can only be achieved with strict diet and medication in a hospital setting. Diet alone is highly demanding of patients, and synthetic drugs that reduce appetite and weight loss tend to have significant side effects.

It is known that the distribution, promotion and increasing consumption of teas from various blends of herbal tea have recently become more prominent.

180751 is a pioneer in the Hungarian patent literature. Hungarian Patent Specification, which discloses tea blends of extremely diverse compositions and indications; recommends teapots. The compositions include a cholesterol-lowering blend that reduces the likelihood of vascular disease, but does not provide a general, complex-effect weight loss tea composition.

From the earlier domestic and international literature we highlight Rápőti-Romváry: Medicinal Plants (Medicina Publishing House, Budapest, 1974) and Weiss: Lehrbuch dér Phytotherapie (Stuttgart, 1974). It works. Some of these literature, folk medicine, and Gizella Petri Verrié, Herbs in Medicine (Medicina, Budapest, 1984), have some drugs known to give their brew a consuming, weight-reducing effect.

A “anti-obesity tea blend” (Herbaria Herbal Company) as well as the Halimbarium Consumer Tea (National Pharmacy Center) are currently available on the domestic market. Their exact composition is not public. The greatest disadvantage of tea mixtures, which can be compiled from the literature, is that the time-consuming cooking and filtration operation can be used to obtain the tea brew. A further disadvantage is that all variants of decoctions are an unpleasant, bitter-tasting liquid that can only be consumed after flavoring. Obviously, sweetening will introduce new carbohydrates into the body or apply artificial flavors.

It is therefore an object of the present invention to provide a method by which the resulting composition achieves a consuming, weight loss effect by natural regulation. It is also an object of the present invention to provide a natural active ingredient.

We used previously known results of folk cure in our experiments. Surprisingly, however, it has been found that the efficacy of drugs and plant parts such as elderflower, mustard seed, dog bark, which have hitherto been shown to have some weight-loss effect, can be significantly enhanced if drugs that have been hitherto considered ineffective or unfavorable.

In our comparative experiments, especially compositions of juniper, yarrow and nettle, and alternatively, the composition of wild pansy with a specific lower and upper limit, showed a leaky, synergistic effect.

The above advantageous effect could be further improved by the method of preparing the respective drugs with a suitable amount of ground powder which can be consumed directly by oral administration. We could clearly prove that this form can have a more intense effect. The potent appetite suppressant property of the directly applied meal is significantly contributing to the effect.

Accordingly, the present invention provides a method of producing a weight loss composition using elderflower, mustard seed, canine bark, such that

5-7% by weight elderflower 4-6% by weight juniper berries 5-7% by weight yarrow 5-7% by weight nettle 5-7% by weight fennel seeds 5-7% by weight dandelion 6-8% by weight blackthorn blossom 5-7% by weight coriander 5-7% by weight caraway seed 20-22% by weight corn mustache 10-12% by weight alder 3-4% by weight lestyángyökér 5-7% by weight mustard seed 5-7% by weight heartsease

obsession

8-12% by weight elderflower 8-12% by weight yarrow 8-12% by weight fennel 8-12% by weight caraway 30-35% by weight alder 15-18% by weight sloe 8-12% by weight corn mustache 8-12% by weight heartsease

drugs directly in the form of a powder having a diameter of 1.5 to 2.2 mm, or directly mixed with pharmaceutical excipients and formulated in tablets, or the mixture of the powder is mixed with 2-5 volumes of hot water or brewed tea. transformed into tea filtrate.

In a preferred embodiment of the process according to the invention, the active ingredient is by weight elderflower wt.% Juniper

HU 205 260 Β

6% by weight yarrow 6 wt% nettle 6% by weight fennel 6% by weight dandelion 7% by weight blackthorn blossom 6% by weight coriander 6% by weight cumin 20% by weight corn mustache 11% by weight alder 3% by weight lestyángyökér 6% by weight mustard seed 6% by weight heartsease using drug mills. It is also possible to act as an active ingredient 9% by weight elderflower 9% by weight yarrow 9% by weight fennel 9% by weight caraway 32% by weight alder 16% by weight sloe 8% by weight corn mustache 8% by weight heartsease

using drug mills.

In the process of the present invention, the mixture of drug powder is formulated into tablets with lactose, sucrose, starch, talc, magnesium stearate, cellulose derivatives or other tableting excipients known per se.

The results of our experiments show that the efficacy of the powder or tablet applied directly orally gives very positive results. Such administration avoids high temperature (scalding) degradation of the active compound combination. A further advantage of this method is that the gastrointestinal tract is directly extracted by the digestive juices so that it can act at higher local (local) concentrations.

Our chromatographic experiments showed that when simulated in vitro, digestive conditions of the stomach (pepsin, acid concentration, etc.) showed a significant increase in drug content compared to simple hot water extraction (tea making).

In another embodiment of the invention, the synergistic drug mixture is converted into a tea brew. Generally, 2 tablespoons of water, preferably 2.5 to 3 decilitres, are prepared for tea by adding 1 tbsp.

The tea brew obtained by the process can also be converted into instant teapots.

The dose is 3x1 mocha spoonful (approx. 1g) daily of the drug mixture directly or 3x500mg of tablet press extract or 3x1g of powdered beverage prepared by conventional brewing.

We recommend intensive treatment for 2-5 months. Obviously, in the event of a malfunction, medical attention should be sought. examination is required.

The results of specific human experiments are shown in Table 1 below.

Table 1

35 year old middle-aged woman 49 year old woman doing light work 50 year old man doing light work Height 178 cm 160 cm 188 cm Normal weight for this 67 kg 55 kg 82 kg The ideal weight for this 65 kg 52 kg 78 kg Weight at the beginning of the cure 109 kg 81 kg 118 kg Overweight is normal 42kg 62.7% 26 kg 47.3% 36 kg 43.9% ideal 44 kg 67.7% 29 kg 52.7% 40 kg 51.3% Weight after 4 months 85 kg 68 kg 102 kg Overweight is normal 18 kg 26.9% 13kg 23.6% 10 kg 24.4% ideal 20 kg 30.8% 16kg 30.8% 24kg 30.8% Weight Loss 24 kg 13 kg 16 kg Weight loss in proportion to excess weight is normal 57.1% 50.0% 44.4% ideal 54.5% 44.8% 40.0% Daily energy requirement 10920 KJ 2600 Kai 7140 KJ 1700 Kai 10,500 KJ 2,500 Kai The average daily food actually consumed 6720 KJ 1600 Kai 4620 KJ 1100 Kai 7140 KJ 1700 Kai

Az'l. Table 4 shows the data obtained during 4 months of treatment with the composition described in Example 1. The reference values were those of the Faculty of Metabolism and Nutrition, Umi University.

The process of the present invention is illustrated by the following examples:

Example 1 Drug Ingredients: Elderflower 50g juniper berries 40g yarrow 50g Nettle 50g Sweet Cumin 50g Dandelion 50g blackthorn flowers 60 g coriander 50g Kitchen Cumin 50g corn Mustache 200 g alder 100 g Lestyángyökér 30g mustard seed 50g heartsease 50g

I

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The above drug mixture is milled on a grinder with a 1.9 mm mesh screen.

Example 2

In each case, as in Example 1, the mixture was compressed into 300 mg tablets after adding 300 g of starch and 150 g of methylcellulose additive and mixing.

Example 3

All of the procedures described in Example 1 were followed except that the powdered drug mixture was packaged in a 200 g pack. When used as a tea drink, it is made into a tea brew before consumption (1 teaspoon of tea mixture in 300 ml of water).

Example 4 Drug Ingredients: Elderflower 50g yarrow 50g Fennel Seed 50g Kitchen Cumin '50 yrs alder 200 g corn Mustache 50g blackthorn flowers 100 g heartsease 50g

The drug mixture was prepared as described in Example 1.

Example 5

The drug powder of Example 4 was treated as in Example 2.

Example 6

In all cases, the procedure of Example 3 was followed except that the drug mixture described in Example 4 was used.

Claims (4)

A process for the preparation of a composition for weight loss using elderflower, mustard seed, canine bark, characterized in that: 5-7% by weight elderflower 4-6% by weight juniper berries 5-7% by weight yarrow 5-7% by weight nettle 5-7% by weight fennel seeds 5-7% by weight dandelion 6-8% by weight blackthorn blossom 5-7% by weight coriander 5-7% by weight caraway seed 20-22% by weight corn mustache 10-12% by weight alder 3-4tömeg% lestyángyökér 5-7% by weight mustard seed 5-7% by weight t heartsease 1 8-12% by weight elderflower 8-12% by weight yarrow 8-12% by weight fennel 8-12% by weight caraway 30-35% by weight alder 15-18% by weight sloe 8-12% by weight corn mustache 8-12% by weight heartsease 1.5-2.2 mm in diameter of the drugs, optionally formulated into tablets by the addition of auxiliary substances known in the pharmaceutical formulations, or the mixture of the powder into 2 to 5 parts by volume of hot tea or tea. transformed into tea filtrate. 2. In la. Process according to claim 1, characterized in that it is an active ingredient 6% by weight elderflower 5% by weight juniper berries 6% by weight yarrow 6% by weight nettle 6% by weight fennel seeds 6% by weight dandelion 7% by weight blackthorn blossom 6% by weight coriander 6% by weight kitchen with stone core outcome 20% by weight corn mustache 11% by weight alder 3% by weight lestyángyökér 6% by weight mustard seed 6% by weight heartsease a mixture of drugs is converted into a directly edible meal. 3. The lb. Process according to claim 1, characterized in that it is an active ingredient 9% by weight elderflower 9% by weight yarrow 9% by weight fennel 9% by weight caraway 32% by weight alder 16% by weight sloe 8% by weight corn mustache 8% by weight heartsease a mixture of drugs is converted into a directly edible meal. 4. A process according to any one of claims 1 to 4, characterized in that the mixture of drug powder is converted into tablets with lactose, sucrose, starch, talc, magnesium stearate, cellulose derivatives or other tableting aids known per se.