HU190434B - Process for the production of 3-trifluor-methyl- and 2,5-dimethyl-4'-hydroxy-alpha-ethyl-benzhydrol,as well as of therapeutci preparations containing them - Google Patents
Process for the production of 3-trifluor-methyl- and 2,5-dimethyl-4'-hydroxy-alpha-ethyl-benzhydrol,as well as of therapeutci preparations containing them Download PDFInfo
- Publication number
- HU190434B HU190434B HU824186A HU418682A HU190434B HU 190434 B HU190434 B HU 190434B HU 824186 A HU824186 A HU 824186A HU 418682 A HU418682 A HU 418682A HU 190434 B HU190434 B HU 190434B
- Authority
- HU
- Hungary
- Prior art keywords
- ethyl
- hydroxy
- trifluoromethyl
- benzhydrol
- dimethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
- C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/11—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
- C07C37/20—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms using aldehydes or ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
- C07C39/367—Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU824186A HU190434B (en) | 1982-12-28 | 1982-12-28 | Process for the production of 3-trifluor-methyl- and 2,5-dimethyl-4'-hydroxy-alpha-ethyl-benzhydrol,as well as of therapeutci preparations containing them |
| AU22909/83A AU558054B2 (en) | 1982-12-28 | 1983-12-23 | 3-trifluoromethyl and 2,5-dimethyl-4-:-hydroxy-2-ethyl benzhydrol |
| CA000444189A CA1211472A (en) | 1982-12-28 | 1983-12-23 | 3-TRIFLUOROMETHYL-AND 2,5-DIMETHYL-4'-HYDROXY-.alpha.- ETHYL-BENZHYDROL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| ES528456A ES528456A0 (es) | 1982-12-28 | 1983-12-27 | Procedimiento de preparacion de 3-trifluorometil- o 2,5-dimetil-4'-hidroxi- -etil-benzol |
| DK602183A DK159904C (da) | 1982-12-28 | 1983-12-27 | Farmaceutiske praeparater indeholdende 3-trifluormethyl-4'-hydroxy-alfa-ethylbenzhydrol samt fremgangsmaade til fremstilling deraf |
| ZA839619A ZA839619B (en) | 1982-12-28 | 1983-12-27 | 3-trifluoromethyl-and 2,5-dimethyl-4'-hydroxy-alpha-ethyl-benzhydrol derivatives,process for their preparation and pharmaceutical compositions containing them |
| IL70554A IL70554A (en) | 1982-12-28 | 1983-12-27 | Pharmaceutical compositions containing 3-trifluoromethyl-or 2,5-dimethyl-4'-hydroxy-alpha-ethyl-benzhydrol |
| FI834794A FI834794A (fi) | 1982-12-28 | 1983-12-27 | Foerfarande foer framstaellning av 3- trifluorometyl- och 2,5-dimetyl-4'-hydroxi- -etyl-benzhydrol. |
| JP58244946A JPS59130824A (ja) | 1982-12-28 | 1983-12-27 | 急性エタノール中毒治療用製薬組成物 |
| US06/565,835 US4593047A (en) | 1982-12-28 | 1983-12-27 | Process for the preparation of 3-trifluoromethyl-and 2,5-dimethyl-4'-hdyroxy-α-ethyl-benzhydrol, and pharmaceutical compositions containing them |
| DE8383113173T DE3379399D1 (en) | 1982-12-28 | 1983-12-28 | Substituted 4'-hydroxy-alpha-ethyl benzhydroles for use as medicaments |
| AT83113173T ATE41413T1 (de) | 1982-12-28 | 1983-12-28 | Substituierte 4'-hydroxy-alpha-aethylbenzhydrole zur verwendung als arnzeimittel. |
| EP83113173A EP0112586B1 (de) | 1982-12-28 | 1983-12-28 | Substituierte 4'-Hydroxy-alpha-äthylbenzhydrole zur Verwendung als Arnzeimittel |
| GR73363A GR79149B (da) | 1982-12-28 | 1983-12-28 | |
| ES543795A ES543795A0 (es) | 1982-12-28 | 1985-06-01 | Procedimiento de preparacion de 3-trifluorometil-4'-hidroxi--a-etil-benzol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU824186A HU190434B (en) | 1982-12-28 | 1982-12-28 | Process for the production of 3-trifluor-methyl- and 2,5-dimethyl-4'-hydroxy-alpha-ethyl-benzhydrol,as well as of therapeutci preparations containing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT34941A HUT34941A (en) | 1985-05-28 |
| HU190434B true HU190434B (en) | 1986-09-29 |
Family
ID=10967251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU824186A HU190434B (en) | 1982-12-28 | 1982-12-28 | Process for the production of 3-trifluor-methyl- and 2,5-dimethyl-4'-hydroxy-alpha-ethyl-benzhydrol,as well as of therapeutci preparations containing them |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4593047A (da) |
| EP (1) | EP0112586B1 (da) |
| JP (1) | JPS59130824A (da) |
| AT (1) | ATE41413T1 (da) |
| AU (1) | AU558054B2 (da) |
| CA (1) | CA1211472A (da) |
| DE (1) | DE3379399D1 (da) |
| DK (1) | DK159904C (da) |
| ES (2) | ES528456A0 (da) |
| FI (1) | FI834794A (da) |
| GR (1) | GR79149B (da) |
| HU (1) | HU190434B (da) |
| IL (1) | IL70554A (da) |
| ZA (1) | ZA839619B (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU191966B (en) * | 1984-10-25 | 1987-04-28 | Richter Gedeon Vegyeszet | Fodder additive and process for producing same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU168432B (da) * | 1973-08-15 | 1976-04-28 | ||
| US4094908A (en) * | 1973-08-15 | 1978-06-13 | Richter Gedeon Vegyeszeti Gyar Rt. | Alpha-substituted benzhydrol derivatives |
| JPS525507A (en) * | 1975-07-02 | 1977-01-17 | Canon Inc | Method of recording data |
| HU190054B (en) * | 1982-12-28 | 1986-08-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for the production of new 4-hydroxi -benzhydrols, as well as of therapeutic preparations contaning them |
-
1982
- 1982-12-28 HU HU824186A patent/HU190434B/hu not_active IP Right Cessation
-
1983
- 1983-12-23 CA CA000444189A patent/CA1211472A/en not_active Expired
- 1983-12-23 AU AU22909/83A patent/AU558054B2/en not_active Ceased
- 1983-12-27 JP JP58244946A patent/JPS59130824A/ja active Granted
- 1983-12-27 ES ES528456A patent/ES528456A0/es active Granted
- 1983-12-27 US US06/565,835 patent/US4593047A/en not_active Expired - Fee Related
- 1983-12-27 DK DK602183A patent/DK159904C/da not_active IP Right Cessation
- 1983-12-27 FI FI834794A patent/FI834794A/fi not_active Application Discontinuation
- 1983-12-27 IL IL70554A patent/IL70554A/xx unknown
- 1983-12-27 ZA ZA839619A patent/ZA839619B/xx unknown
- 1983-12-28 AT AT83113173T patent/ATE41413T1/de not_active IP Right Cessation
- 1983-12-28 GR GR73363A patent/GR79149B/el unknown
- 1983-12-28 EP EP83113173A patent/EP0112586B1/de not_active Expired
- 1983-12-28 DE DE8383113173T patent/DE3379399D1/de not_active Expired
-
1985
- 1985-06-01 ES ES543795A patent/ES543795A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8603804A1 (es) | 1986-01-01 |
| GR79149B (da) | 1984-10-02 |
| DE3379399D1 (en) | 1989-04-20 |
| EP0112586A3 (en) | 1987-01-07 |
| AU2290983A (en) | 1984-07-05 |
| DK159904C (da) | 1991-05-21 |
| ES543795A0 (es) | 1986-01-01 |
| DK602183A (da) | 1984-06-29 |
| ES8600189A1 (es) | 1985-10-01 |
| DK602183D0 (da) | 1983-12-27 |
| HUT34941A (en) | 1985-05-28 |
| DK159904B (da) | 1990-12-31 |
| ZA839619B (en) | 1984-08-29 |
| FI834794A0 (fi) | 1983-12-27 |
| AU558054B2 (en) | 1987-01-15 |
| JPH0246007B2 (da) | 1990-10-12 |
| IL70554A (en) | 1986-09-30 |
| ATE41413T1 (de) | 1989-04-15 |
| EP0112586B1 (de) | 1989-03-15 |
| IL70554A0 (en) | 1984-03-30 |
| FI834794A (fi) | 1984-06-29 |
| EP0112586A2 (de) | 1984-07-04 |
| JPS59130824A (ja) | 1984-07-27 |
| ES528456A0 (es) | 1985-10-01 |
| US4593047A (en) | 1986-06-03 |
| CA1211472A (en) | 1986-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3784478T2 (de) | Benzopyran-verbindungen, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. | |
| JP2008509953A (ja) | ４−［［（７ｒ）−８−シクロペンチル−７−エチル−５，６，７，８−テトラヒドロ−５−メチル−４−６−オキソ−２−ピペリジニル］アミノ］−３−メトキシ−ｎ−（１−メチル−４−ピペリジニル）ベンズアミドの水和物及び多形、その製造方法、並びにその薬物としての使用 | |
| JP2661699B2 (ja) | ピペリジンオピオイド拮抗剤 | |
| US20040162324A1 (en) | Thienylazolylalkoxyethanamines, their preparation and their application as medicaments | |
| EP0047536A2 (en) | Substituted propylamines | |
| EP0115080B1 (de) | (Omega-(Diäthylamino)-alkoxy)-alpha-(äthyl)-benzhydrolderivate, ihre Säureadditionssalze und quaternären Salze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel | |
| JPH0670026B2 (ja) | １，４−二置換ピペラジン誘導体、これを含む薬剤組成物およびその製造方法 | |
| JPS59134756A (ja) | ジアルキルアミノアルコキシベンジルアルコ−ル誘導体 | |
| JPH0130821B2 (da) | ||
| JPS6348872B2 (da) | ||
| HU190434B (en) | Process for the production of 3-trifluor-methyl- and 2,5-dimethyl-4'-hydroxy-alpha-ethyl-benzhydrol,as well as of therapeutci preparations containing them | |
| HU190054B (en) | Process for the production of new 4-hydroxi -benzhydrols, as well as of therapeutic preparations contaning them | |
| SK15032000A3 (sk) | Maleínan paroxetínu, spôsob jeho výroby a jeho použitie | |
| HU188239B (en) | Process for the production of new resorcinol-derivatives and of therapeutic preparations containing them | |
| SK6412000A3 (en) | Biphenyl derivatives as pharmaceuticals | |
| JPH0348907B2 (da) | ||
| HU190053B (en) | Process for the production of new 1,1-diphenyl-propanol-derivatives, as well as of therapeutic preparations containing them | |
| HU188170B (en) | Process for producing 3-square bracket-2-bracket-tetra-or hexahydro.4-pyridyl-bracket closed-ethyl-s uare bracket closed-indola derivatives | |
| CA1217724A (fr) | Compositions pharmaceutiques utiles comme antiarythmiques | |
| SK15902000A3 (sk) | 10-gáforsulfonát paroxetínu, spôsob jeho výroby a jeho použitie | |
| JPH0159264B2 (da) | ||
| MXPA00010435A (en) | Paroxetine 10-camphorsulfonate for treatment of cns disorders | |
| MXPA00009884A (en) | Paroxetine maleate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |