HU190399B - Process for the production of e-homo-eburnane-derivatives - Google Patents

Process for the production of e-homo-eburnane-derivatives Download PDF

Info

Publication number
HU190399B
HU190399B HU822130A HU213082A HU190399B HU 190399 B HU190399 B HU 190399B HU 822130 A HU822130 A HU 822130A HU 213082 A HU213082 A HU 213082A HU 190399 B HU190399 B HU 190399B
Authority
HU
Hungary
Prior art keywords
formula
hydrogen
acid addition
acid
pharmaceutically acceptable
Prior art date
Application number
HU822130A
Other languages
English (en)
Hungarian (hu)
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Janos Sapi
Eva Palosi
Egon Karpati
Laszlo Szporny
Original Assignee
Richter Gedeon Vegyeszeti Gyar Rt,Hu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar Rt,Hu filed Critical Richter Gedeon Vegyeszeti Gyar Rt,Hu
Priority to HU822130A priority Critical patent/HU190399B/hu
Priority to BE1/10822A priority patent/BE897147A/fr
Priority to GR71805A priority patent/GR78602B/el
Priority to GB08317611A priority patent/GB2122994B/en
Priority to AU16395/83A priority patent/AU553966B2/en
Priority to SE8303718A priority patent/SE8303718L/sv
Priority to NZ204756A priority patent/NZ204756A/en
Priority to CH3566/83A priority patent/CH660735A5/de
Priority to PT76950A priority patent/PT76950B/pt
Priority to IL69106A priority patent/IL69106A/xx
Priority to DK300383A priority patent/DK300383A/da
Priority to NL8302297A priority patent/NL8302297A/nl
Priority to CA000431510A priority patent/CA1192189A/en
Priority to AT238983A priority patent/AT383599B/de
Priority to ES523696A priority patent/ES8500620A1/es
Priority to FR8310733A priority patent/FR2529554B1/fr
Priority to JP58117176A priority patent/JPS5913782A/ja
Priority to DE19833323584 priority patent/DE3323584A1/de
Publication of HU190399B publication Critical patent/HU190399B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU822130A 1982-06-30 1982-06-30 Process for the production of e-homo-eburnane-derivatives HU190399B (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
HU822130A HU190399B (en) 1982-06-30 1982-06-30 Process for the production of e-homo-eburnane-derivatives
BE1/10822A BE897147A (fr) 1982-06-30 1983-06-28 Derives de e-homo-eburnane, procede pour leur preparation et compositions pharmaceutiques contenant ces composes
GR71805A GR78602B (sv) 1982-06-30 1983-06-29
GB08317611A GB2122994B (en) 1982-06-30 1983-06-29 E-homo-eburnane derivatives
AU16395/83A AU553966B2 (en) 1982-06-30 1983-06-29 E-homo-eburnane derivatives
SE8303718A SE8303718L (sv) 1982-06-30 1983-06-29 E-homo-enurnanderivat, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande dessa foreningar
NZ204756A NZ204756A (en) 1982-06-30 1983-06-29 E-homo-eburnane derivatives and pharmaceutical compositions
CH3566/83A CH660735A5 (de) 1982-06-30 1983-06-29 Neue e-homo-eburnan-derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittelpraeparate.
PT76950A PT76950B (en) 1982-06-30 1983-06-29 Process for the preparation of racemic or optically active e-homo-eburnane derivatives and pharmaceutical compositions containing them
IL69106A IL69106A (en) 1982-06-30 1983-06-29 Alkyl 14-oxo-e-homo-eburna-menine-15-carboxylates,process for their preparation and pharmaceutical compositions containing them
DK300383A DK300383A (da) 1982-06-30 1983-06-29 Racemiske eller optisk aktive e-homo-eburanderivater eller syreadditionssalte deraf, deres fremstilling og anvendelse
NL8302297A NL8302297A (nl) 1982-06-30 1983-06-29 E-homoeburnaanderivaten, werkwijze voor hun bereiding, alsmede farmaceutische samenstellingen welke deze verbindingen bevatten.
CA000431510A CA1192189A (en) 1982-06-30 1983-06-29 E-homo-eburnane derivatives and a process for preparing same
AT238983A AT383599B (de) 1982-06-30 1983-06-29 Verfahren zur herstellung von neuen racemischen und optisch aktiven e-homo-eburnan-derivaten sowievon saeureadditions-salzen derselben
ES523696A ES8500620A1 (es) 1982-06-30 1983-06-29 Procedimiento para la preparacion de derivados e-homo-eburnanos racemicos u opticamente activos y de sus sales de adicion acidas.
FR8310733A FR2529554B1 (fr) 1982-06-30 1983-06-29 Derives de e-homo-eburnane, procede pour leur preparation et compositions pharmaceutiques contenant ces composes
JP58117176A JPS5913782A (ja) 1982-06-30 1983-06-30 Ｅ−ホモ−エブルナン誘導体及びその製造方法並びに該化合物を含有する医薬製剤
DE19833323584 DE3323584A1 (de) 1982-06-30 1983-06-30 14-oxo-15-alkoxycarbonyl-e-homoeburnane, verfahren zur herstellung derselben und diese enthaltende arzneimittel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU822130A HU190399B (en) 1982-06-30 1982-06-30 Process for the production of e-homo-eburnane-derivatives

Publications (1)

Publication Number Publication Date
HU190399B true HU190399B (en) 1986-08-28

Family

ID=10957916

Family Applications (1)

Application Number Title Priority Date Filing Date
HU822130A HU190399B (en) 1982-06-30 1982-06-30 Process for the production of e-homo-eburnane-derivatives

Country Status (17)

Country Link
JP (1) JPS5913782A (sv)
AU (1) AU553966B2 (sv)
BE (1) BE897147A (sv)
CA (1) CA1192189A (sv)
CH (1) CH660735A5 (sv)
DE (1) DE3323584A1 (sv)
DK (1) DK300383A (sv)
ES (1) ES8500620A1 (sv)
FR (1) FR2529554B1 (sv)
GB (1) GB2122994B (sv)
GR (1) GR78602B (sv)
HU (1) HU190399B (sv)
IL (1) IL69106A (sv)
NL (1) NL8302297A (sv)
NZ (1) NZ204756A (sv)
PT (1) PT76950B (sv)
SE (1) SE8303718L (sv)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181496B (en) * 1979-08-13 1983-07-28 Richter Gedeon Vegyeszet Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes

Also Published As

Publication number Publication date
IL69106A (en) 1986-02-28
CA1192189A (en) 1985-08-20
PT76950A (en) 1983-07-01
FR2529554A1 (fr) 1984-01-06
DE3323584A1 (de) 1984-02-09
SE8303718L (sv) 1983-12-31
FR2529554B1 (fr) 1985-08-09
CH660735A5 (de) 1987-06-15
NL8302297A (nl) 1984-01-16
SE8303718D0 (sv) 1983-06-29
AU1639583A (en) 1984-01-05
JPS5913782A (ja) 1984-01-24
IL69106A0 (en) 1983-10-31
ES523696A0 (es) 1984-11-01
ES8500620A1 (es) 1984-11-01
GB2122994A (en) 1984-01-25
AU553966B2 (en) 1986-07-31
BE897147A (fr) 1983-12-28
NZ204756A (en) 1985-09-13
DK300383D0 (da) 1983-06-29
DK300383A (da) 1983-12-31
GB8317611D0 (en) 1983-08-03
GR78602B (sv) 1984-09-27
GB2122994B (en) 1985-08-29
PT76950B (en) 1986-01-24

Similar Documents

Publication Publication Date Title
CA2166203C (en) Processes and intermediates for the preparation of 5-[2-(4-(benzoisothiazol-3-yl)-piperazin-1-yl)ethyl]- 6-chloro-1,3-dihydro-indol-2-one
US4556653A (en) Pyrido[1,5]benzodiazepinone derivatives and pharmacological activities thereof
EP1565444A1 (en) Sinomenine and sinomenine compounds, synthesis and use
WO2007129111A1 (en) Diazepine derivatives as 5-ht2a antagonists
EP0974583B1 (en) Phenylpiperidine derivatives
FR2674849A1 (fr) Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique.
EP0008249B1 (fr) Dérivés de fluorènes et fluoranthènes, leur procédé de préparation et leur application en thérapeutique
EP0180834B1 (de) 4-Alkoxy-pyrido[2,3-d]pyrimidin-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
EP0173933B1 (de) 1,6-Naphthyridin-Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
HUT71132A (en) Bis-aryl-carbinol derivatives, pharmaceutical compositions containing them and process for producing
IE913005A1 (en) Indolonaphthyridines
EP0234516B1 (de) 1,6-Naphthyridin-Derivate,Verfahren zu deren Herstellung und diese enthaltende Arzneimittel zur Behandlung von Gefässerkrankungen
EP0266308B1 (de) Indolo-pyrazino-benzodiazepin-Derivate
US3086972A (en) Aza-thiaxanthene derivatives
HU190399B (en) Process for the production of e-homo-eburnane-derivatives
EP0378468A2 (fr) Dérivés des bisarylalcènes, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
HU180868B (en) Process for producing sub 5-substituted 10,11-dihydro-5h-dibenzo-bracket-a,b-bracket closed-cycloheptene-5,10-imine derivatives
US4481204A (en) E-Homo-eburnane derivatives, process for their preparation, and pharmaceutical compositions containing these compounds
HU191548B (en) Process for the production of 1-cyclohexyl-3,4-dihydro-iziquinoline-derivatives
HU187140B (en) Process for preparing new aburnan-oxima ethers
DE2016268C3 (de) (4aRS, 5SR, 9bSR)- und (4aRS, 5SR, 9bRS) -13,4,4a3,9b-Hexahydro-5-phenyl2H-indeno [Uc] pyridine, ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel
AT414305B (de) Neue (3aalpha,8balpha)-1,2,3,3a,4,8b-hexahydro- pyrrolo(2',3':3,4) cyclopenta(1,2-b)- pyridin-derivate, verfahren zu ihrer herstellung und ihre verwendung
EP0189870A1 (de) 5-Alkoxy-pyrido [4,3-d] pyrimidine Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE3602655A1 (de) 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
HU190400B (en) Process for preparing new eburnan-oxime derivatives