HRP970186B1 - Novel 2,3-benzodiazepine derivatives - Google Patents

Novel 2,3-benzodiazepine derivatives

Info

Publication number
HRP970186B1
HRP970186B1 HR970186A HRP970186A HRP970186B1 HR P970186 B1 HRP970186 B1 HR P970186B1 HR 970186 A HR970186 A HR 970186A HR P970186 A HRP970186 A HR P970186A HR P970186 B1 HRP970186 B1 HR P970186B1
Authority
HR
Croatia
Prior art keywords
novel
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
HR970186A
Other languages
English (en)
Inventor
Istvan Ling
Gizella Abraham
Pal Berzsenyi
Istvan Tarnawa
Sandor Solyom
Ferenc Andrasi
Tamas Hamori
Emese Csuzdi
Katalin Horvath
Melinda Gal
Imre Moravicsik
Marta Szoellosy
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of HRP970186A2 publication Critical patent/HRP970186A2/hr
Publication of HRP970186B1 publication Critical patent/HRP970186B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR970186A 1996-04-04 1997-04-03 Novel 2,3-benzodiazepine derivatives HRP970186B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9600871A HU9600871D0 (en) 1996-04-04 1996-04-04 New 2,3-benzodiazepine derivatives
US08/832,777 US5807851A (en) 1996-04-04 1997-04-04 2,3-Benzodiazepine Derivatives as non-competitive AMPA

Publications (2)

Publication Number Publication Date
HRP970186A2 HRP970186A2 (en) 1998-10-31
HRP970186B1 true HRP970186B1 (en) 2002-06-30

Family

ID=89993863

Family Applications (1)

Application Number Title Priority Date Filing Date
HR970186A HRP970186B1 (en) 1996-04-04 1997-04-03 Novel 2,3-benzodiazepine derivatives

Country Status (13)

Country Link
US (1) US5807851A (fr)
EP (1) EP0802195B1 (fr)
JP (1) JP3131767B2 (fr)
AU (1) AU1636297A (fr)
CZ (1) CZ291520B6 (fr)
EA (1) EA000471B1 (fr)
FR (1) FR2747121B1 (fr)
GB (1) GB2311779B (fr)
GR (1) GR1002883B (fr)
HR (1) HRP970186B1 (fr)
HU (1) HU9600871D0 (fr)
PL (1) PL319270A1 (fr)
SK (1) SK282258B6 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19604919A1 (de) 1996-02-01 1997-08-07 Schering Ag Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
KR100850728B1 (ko) 2000-06-12 2008-08-06 에자이 알앤드디 매니지먼트 가부시키가이샤 1,2-디하이드로피리딘 화합물, 그의 제조 방법 및 그의 용도
HU225100B1 (hu) * 2000-12-21 2006-06-28 Egyt Gyogyszervegyeszeti Gyar 2,3-Benzodiazepinszármazékok, ilyen hatóanyagot tartalmazó gyógyászati készítmények és alkalmazásuk
GB0129260D0 (en) 2001-12-06 2002-01-23 Eisai London Res Lab Ltd Pharmaceutical compositions and their uses
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
US6858605B2 (en) 2003-02-04 2005-02-22 Ivax Drug Research Institute, Ltd. Substituted 2,3-benzodiazepine derivatives
HUP0302449A3 (en) * 2003-08-04 2005-06-28 Egis Gyogyszergyar Nyilvanosan 8-chloro-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for producing them
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
US20090233913A1 (en) * 2005-12-30 2009-09-17 Istvan Ling Optical isomers of dihydro-2,3-benzodiazepines and their stereoselective synthesis
EP2338492A1 (fr) 2009-12-24 2011-06-29 Universidad del Pais Vasco Procédés et compositions pour le traitement de la maladie d'Alzheimer
CN104755473B (zh) * 2012-08-16 2017-03-08 拜耳医药股份有限公司 2，3‑苯并二氮杂*
WO2016062688A1 (fr) * 2014-10-23 2016-04-28 Bayer Pharma Aktiengesellschaft Dérivés de 1-phényl-4,5-dihydro-3h-2,3-benzodiazépines
AU2019395288A1 (en) 2018-12-14 2021-09-23 Eisai R&D Management Co., Ltd. Aqueous based pharmaceutical formulations of 1,2-dihydropyridine compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
HU208429B (en) * 1991-05-03 1993-10-28 Gyogyszerkutato Intezet Process for producing 1-/3-chloro-phenyl/-4-methyl-7,8-dimethoxy-5h-2,3-benzodiazepine of high purity

Also Published As

Publication number Publication date
GB9706945D0 (en) 1997-05-21
PL319270A1 (en) 1997-10-13
FR2747121A1 (fr) 1997-10-10
GB2311779A (en) 1997-10-08
CZ291520B6 (cs) 2003-03-12
HU9600871D0 (en) 1996-05-28
EP0802195A3 (fr) 1997-12-03
FR2747121B1 (fr) 1998-08-21
AU1636297A (en) 1997-10-09
US5807851A (en) 1998-09-15
EP0802195A2 (fr) 1997-10-22
EA199700030A2 (ru) 1997-09-30
JP3131767B2 (ja) 2001-02-05
EP0802195B1 (fr) 2003-11-19
EA199700030A3 (ru) 1997-12-30
SK42397A3 (en) 1998-01-14
GB2311779B (en) 1999-07-14
JPH1036356A (ja) 1998-02-10
SK282258B6 (sk) 2001-12-03
GR1002883B (el) 1998-03-24
EA000471B1 (ru) 1999-08-26
CZ97897A3 (en) 1997-10-15
HRP970186A2 (en) 1998-10-31

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Legal Events

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A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
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Payment date: 20030403

Year of fee payment: 7

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Effective date: 20040404