HRP970083A2 - Polysaccharide precipitation process - Google Patents

Polysaccharide precipitation process

Info

Publication number
HRP970083A2
HRP970083A2 HR9608546.9A HRP970083A HRP970083A2 HR P970083 A2 HRP970083 A2 HR P970083A2 HR P970083 A HRP970083 A HR P970083A HR P970083 A2 HRP970083 A2 HR P970083A2
Authority
HR
Croatia
Prior art keywords
polysaccharides
polysaccharide
process according
salt
pneumococcus
Prior art date
Application number
HR9608546.9A
Other languages
English (en)
Croatian (hr)
Inventor
Russel J Lander
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9608546A external-priority patent/GB9608546D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of HRP970083A2 publication Critical patent/HRP970083A2/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HR9608546.9A 1996-02-14 1997-02-13 Polysaccharide precipitation process HRP970083A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1163196P 1996-02-14 1996-02-14
GB9608546A GB9608546D0 (en) 1996-04-25 1996-04-25 Polysaccharide precipitation process

Publications (1)

Publication Number Publication Date
HRP970083A2 true HRP970083A2 (en) 1998-04-30

Family

ID=26309205

Family Applications (1)

Application Number Title Priority Date Filing Date
HR9608546.9A HRP970083A2 (en) 1996-02-14 1997-02-13 Polysaccharide precipitation process

Country Status (13)

Country Link
EP (1) EP0897427B1 (de)
JP (1) JP3990455B2 (de)
AR (1) AR005869A1 (de)
AT (1) ATE280834T1 (de)
AU (1) AU724862B2 (de)
CA (1) CA2245588C (de)
DE (1) DE69731380T2 (de)
DK (1) DK0897427T3 (de)
ES (1) ES2229336T3 (de)
HR (1) HRP970083A2 (de)
PT (1) PT897427E (de)
TW (1) TW411344B (de)
WO (1) WO1997030171A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
US20070184072A1 (en) * 2005-04-08 2007-08-09 Wyeth Multivalent pneumococcal polysaccharide-protein conjugate composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2388563A1 (fr) * 1977-04-29 1978-11-24 Fabre Sa Pierre Vaccins acellulaires perfectionnes contenant des polysaccharides capsulaires
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4686102A (en) * 1984-04-12 1987-08-11 American Cyanamid Company Multivalent pneumococcal vaccine and preparation thereof
US4695624A (en) * 1984-05-10 1987-09-22 Merck & Co., Inc. Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
US4877613A (en) * 1987-08-05 1989-10-31 Biotech Connections, Inc. Process for preparing veterinary acellular vaccines against gram-negative nonenteric pathogenic bacilli
US5192540A (en) * 1988-04-19 1993-03-09 American Cyanamid Company Haemophilus influenzae type b oxidized polysaccharide-outer membrane protein conjugate vaccine
SK18594A3 (en) * 1991-08-16 1994-08-10 Merck & Co Inc Method of production of capsular polysacharide without lipid and endotoxine
US5371197A (en) * 1991-09-24 1994-12-06 Merck & Co., Inc. Protein-dimeric polysaccharide conjugate vaccine
US5445817A (en) * 1992-08-21 1995-08-29 The United States Of America As Represented By The Department Of Health And Human Services Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines

Also Published As

Publication number Publication date
DE69731380T2 (de) 2006-02-23
DK0897427T3 (da) 2005-02-14
AU724862B2 (en) 2000-10-05
ATE280834T1 (de) 2004-11-15
EP0897427B1 (de) 2004-10-27
AR005869A1 (es) 1999-07-21
CA2245588C (en) 2006-05-09
PT897427E (pt) 2005-01-31
AU2267797A (en) 1997-09-02
CA2245588A1 (en) 1997-08-21
JP2000506383A (ja) 2000-05-30
JP3990455B2 (ja) 2007-10-10
WO1997030171A1 (en) 1997-08-21
EP0897427A1 (de) 1999-02-24
TW411344B (en) 2000-11-11
DE69731380D1 (de) 2004-12-02
ES2229336T3 (es) 2005-04-16

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODBC Application rejected