HRP960199B1 - SYNTHESIS OF AN INTERMEDIATE FOR THE PREPARATION OF 5,6-DIHYDRO-(S)-4-(ETHYLAMINO)-(S)-6-METHYL-4H-THIENO(2,3-b)THIOPYRAN-2-SULFONAMIDE 7,7-DIOXIDE INTERMEDIATES AND RELATED COMPOUNDS - Google Patents

SYNTHESIS OF AN INTERMEDIATE FOR THE PREPARATION OF 5,6-DIHYDRO-(S)-4-(ETHYLAMINO)-(S)-6-METHYL-4H-THIENO(2,3-b)THIOPYRAN-2-SULFONAMIDE 7,7-DIOXIDE INTERMEDIATES AND RELATED COMPOUNDS

Info

Publication number
HRP960199B1
HRP960199B1 HR960199A HRP960199A HRP960199B1 HR P960199 B1 HRP960199 B1 HR P960199B1 HR 960199 A HR960199 A HR 960199A HR P960199 A HRP960199 A HR P960199A HR P960199 B1 HRP960199 B1 HR P960199B1
Authority
HR
Croatia
Prior art keywords
thiopyran
thieno
ethylamino
sulfonamide
dihydro
Prior art date
Application number
HR960199A
Other languages
English (en)
Inventor
David J Mathre
Paul Sohar
Lynn May Brown
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of HRP960199A2 publication Critical patent/HRP960199A2/hr
Publication of HRP960199B1 publication Critical patent/HRP960199B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HR960199A 1995-04-26 1996-04-24 SYNTHESIS OF AN INTERMEDIATE FOR THE PREPARATION OF 5,6-DIHYDRO-(S)-4-(ETHYLAMINO)-(S)-6-METHYL-4H-THIENO(2,3-b)THIOPYRAN-2-SULFONAMIDE 7,7-DIOXIDE INTERMEDIATES AND RELATED COMPOUNDS HRP960199B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/430,214 US5574176A (en) 1995-04-26 1995-04-26 Synthesis of an intermediate for the preparation of 5,6-dihydro-(s)-4-(ethylamino)-(s)-6-methyl-4h-thieno [2,3-b]thiopyran-2-sulfonamide 7,7-dioxide intermediates and related compounds

Publications (2)

Publication Number Publication Date
HRP960199A2 HRP960199A2 (en) 1998-02-28
HRP960199B1 true HRP960199B1 (en) 2002-02-28

Family

ID=23706561

Family Applications (1)

Application Number Title Priority Date Filing Date
HR960199A HRP960199B1 (en) 1995-04-26 1996-04-24 SYNTHESIS OF AN INTERMEDIATE FOR THE PREPARATION OF 5,6-DIHYDRO-(S)-4-(ETHYLAMINO)-(S)-6-METHYL-4H-THIENO(2,3-b)THIOPYRAN-2-SULFONAMIDE 7,7-DIOXIDE INTERMEDIATES AND RELATED COMPOUNDS

Country Status (10)

Country Link
US (1) US5574176A (xx)
EP (1) EP0824532A1 (xx)
JP (1) JP3064017B2 (xx)
AR (1) AR000014A1 (xx)
AU (1) AU704210B2 (xx)
CA (1) CA2218654C (xx)
HR (1) HRP960199B1 (xx)
TW (1) TW394767B (xx)
WO (1) WO1996033990A1 (xx)
YU (1) YU25196A (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0748804B1 (en) * 1994-12-28 2001-03-14 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for producing carboxylic acid derivative
EP0748803B1 (en) * 1994-12-28 2001-04-04 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for producing carboxylic acid derivative
US5760249A (en) * 1995-08-29 1998-06-02 Merck & Co., Inc. Synthesis of hydroxysulfone and related compounds
DE602005003672T2 (de) * 2004-07-09 2008-11-20 Fdc Ltd. VERBESSERTES VERFAHREN ZUR HERSTELLUNG VON 5,6 -DIHYDRO -4H-4(S)-ETHYLAMIN-6(S)-METHYLTHIENOÄ2,3-bÜ THIOPYRAN-2-SULFONAMID- 7,7 -DIOXID UND SEINEN SALZEN
CN114891838B (zh) * 2022-04-29 2023-09-08 株洲壹诺生物技术有限公司 盐酸多佐胺中间体(s)-3-(2-噻吩硫基)-丁酸的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4113968A (en) * 1974-10-03 1978-09-12 Kuraray Co., Ltd. Process for preparation of substituted cyclopropane carboxylic acids and esters thereof and intermediates of said acids and esters
US4797413A (en) * 1986-05-14 1989-01-10 Merck & Co., Inc. Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use
US4968815A (en) * 1990-04-16 1990-11-06 Merck & Co., Inc. Synthesis of (S)-3-(thien-2-ylthio)butyric acid analogs
US4968814A (en) * 1990-04-18 1990-11-06 Merck & Co., Inc. (S)-Alkyl 3-(thien-2-ylthio)butyrate and analogs and synthesis thereof

Also Published As

Publication number Publication date
TW394767B (en) 2000-06-21
EP0824532A1 (en) 1998-02-25
AU704210B2 (en) 1999-04-15
AU5488596A (en) 1996-11-18
CA2218654C (en) 2002-09-17
US5574176A (en) 1996-11-12
WO1996033990A1 (en) 1996-10-31
YU25196A (sh) 1999-03-04
HRP960199A2 (en) 1998-02-28
CA2218654A1 (en) 1996-10-31
AR000014A1 (es) 1997-03-12
JPH10507774A (ja) 1998-07-28
JP3064017B2 (ja) 2000-07-12

Similar Documents

Publication Publication Date Title
PL322277A1 (en) Derivatives of pyrazol-4-ylobenzoyl
GB2319250B (en) Derivatives of 6,8-Difluoro-7-Hydroxycoumarin
HUP0100779A3 (en) Novel derivatives of 3,3-diphenylpropylamines
PL327998A1 (en) Novel derivatives of 19-nor-pregnene
PL338563A1 (en) Substituted derivatives of 1,2,3,4-tetrahydronaphtalene
PL324992A1 (en) Novel derivatives of 2,3-dioxotetrahydoquinoxaline
PL324451A1 (en) Derivatives of diphenylmethylenepiperidine
EP0754407A3 (en) Liquid compositions of 1,2-benzisothiazolin-3-one
PL329121A1 (en) Substituted derivatives of 1,2,3,4-tetrahydronaphtalene
IL118294A0 (en) Preparation of 4-aryl-piperidine derivatives
IL132532A (en) Intermediates for the preparation of substituted cephalosporins
PL326604A1 (en) Derivatives of 5"-dezoxy-cytidin
IL116924A (en) Preparation of n-aryl - and n-hetarylhydroxylamines
AU8758298A (en) Process for the preparation of 2'-fluoro-5-methyl-beta -l-arabinofuranosyluridine
IL117574A0 (en) Processes for the preparation of cyclobutanone derivatives
HUP9901176A3 (en) Process for the preparation of 2,2'-bipyrrolyl-pyrromethene (prodigiosins) derivatives and their intermediates
HRP960199B1 (en) SYNTHESIS OF AN INTERMEDIATE FOR THE PREPARATION OF 5,6-DIHYDRO-(S)-4-(ETHYLAMINO)-(S)-6-METHYL-4H-THIENO(2,3-b)THIOPYRAN-2-SULFONAMIDE 7,7-DIOXIDE INTERMEDIATES AND RELATED COMPOUNDS
IL118200A0 (en) Process for the preparation of substituted 2-fluoro-pyrimidines
HUP9903751A3 (en) Intermediates for the preparation of 2-imidazoline-5-ones
IL118973A0 (en) Process for the preparation of substituted aminocarbonyltriazolinones
IL108595A0 (en) Novel derivatives of tetramethylcyclopropane
AU3962999A (en) The method of microobjects' study
PL330141A1 (en) Novel derivatives of 10,11-dihydro-10-oxo-5h-dibezyl(b,f)-azepin-5-carboxagmide
PL325816A1 (en) Novel derivatives of naphtylpiperazine
HUP9901543A3 (en) Process for the preparation of hydroxysulfone derivatives

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20030401

Year of fee payment: 8

PBON Lapse due to non-payment of renewal fee

Effective date: 20040425