HRP921482B1 - Stable formulation of enalapril salt, a process for the preparation thereof and the use thereof - Google Patents
Stable formulation of enalapril salt, a process for the preparation thereof and the use thereofInfo
- Publication number
- HRP921482B1 HRP921482B1 HRP-1842/91A HRP921482A HRP921482B1 HR P921482 B1 HRP921482 B1 HR P921482B1 HR P921482 A HRP921482 A HR P921482A HR P921482 B1 HRP921482 B1 HR P921482B1
- Authority
- HR
- Croatia
- Prior art keywords
- sodium
- enalapril
- stable formulation
- chem
- formula
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HRP-1842/91A HRP921482B1 (en) | 1991-11-25 | 1992-12-30 | Stable formulation of enalapril salt, a process for the preparation thereof and the use thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU184291A YU48602B (sh) | 1991-11-25 | 1991-11-25 | Postupak za dobijanje stabilne formulacije soli enalaprila |
HRP-1842/91A HRP921482B1 (en) | 1991-11-25 | 1992-12-30 | Stable formulation of enalapril salt, a process for the preparation thereof and the use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
HRP921482A2 HRP921482A2 (en) | 1996-12-31 |
HRP921482B1 true HRP921482B1 (en) | 2000-04-30 |
Family
ID=25555813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP-1842/91A HRP921482B1 (en) | 1991-11-25 | 1992-12-30 | Stable formulation of enalapril salt, a process for the preparation thereof and the use thereof |
Country Status (11)
Country | Link |
---|---|
US (1) | US5350582A (xx) |
EP (1) | EP0545194B1 (xx) |
AT (1) | ATE150650T1 (xx) |
CA (1) | CA2083683C (xx) |
DE (1) | DE69218557T2 (xx) |
DK (1) | DK0545194T3 (xx) |
ES (1) | ES2101004T3 (xx) |
GR (1) | GR3023655T3 (xx) |
HR (1) | HRP921482B1 (xx) |
SI (1) | SI9111842A (xx) |
YU (1) | YU48602B (xx) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2128199C (en) * | 1994-07-15 | 1997-02-04 | Bernard Charles Sherman | Stable solid pharmaceutical compositions containing enalapril maleate |
US5573780A (en) * | 1995-08-04 | 1996-11-12 | Apotex Usa Inc. | Stable solid formulation of enalapril salt and process for preparation thereof |
GB9521781D0 (en) * | 1995-10-24 | 1996-01-03 | Merck Sharp & Dohme | Therapeutic agents |
ES2125198B1 (es) * | 1997-05-13 | 1999-11-16 | Vita Invest Sa | Asociacion a dosis fija de un inhibidor de la enzima convertidora de angiotensina y de un antagonista de los canales de calcio, procedimiento para su preparacion y su utilizacion para el tratamiento de enfermees cardiovasculares. |
CA2302832A1 (en) * | 1998-07-21 | 2000-02-03 | Kaneka Corporation | Method for crystallizing maleic acid salt of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanyl-l-proline |
NZ333206A (en) | 1998-12-08 | 2000-07-28 | Bernard Charles Sherman | Solid pharmaceutical compositions comprising a stable magnesium salt of quinapril that acts as a ACE (Angiotensin Converting Enzyme) inhibitor |
US6637359B1 (en) * | 1998-12-15 | 2003-10-28 | Maritrans Inc. | System and method for internally fitting a new inner hull to an existing outer hull to form a rebuilt double hull vessel |
US6764694B1 (en) * | 1999-08-31 | 2004-07-20 | Mutual Pharmaceutical Co., Inc. | Stable formulations of ACE inhibitors, and methods for preparation thereof |
US6555551B1 (en) | 1999-08-31 | 2003-04-29 | Mutual Pharmaceutical Co., Inc. | Stable formulations of ACE inhibitors, and methods for preparation thereof |
US20040157911A1 (en) * | 1999-08-31 | 2004-08-12 | Spiridon Spireas | Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof |
US20030225124A1 (en) * | 1999-08-31 | 2003-12-04 | Spiridon Spireas | Stable formulations of ACE inhibitors, and methods for preparation thereof |
HU226950B1 (en) * | 1999-11-03 | 2010-03-29 | Richter Gedeon Nyrt | The magnesium salt of enalapril and antihypertensive pharmaceutical composition containing it |
US20030215526A1 (en) * | 2002-03-08 | 2003-11-20 | Scott Stofik | Stable formulations of angiotensin converting enzyme (ACE) inhibitors |
JP4948392B2 (ja) * | 2004-03-29 | 2012-06-06 | レ ラボラトア セルビエ | 固形薬学的組成物を調製するためのプロセス |
SI21800A (sl) * | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
RS53324B (en) | 2005-11-17 | 2014-10-31 | Silverstone Pharma Est. | STABLE FORMULATION OF AMORPHIC SALES OF PERINDOPRIL, PROCEDURE FOR THEIR PREPARATION, IN PARTICULAR INDUSTRIAL PREPARATION, AND THEIR USE IN HYPERTENSION THERAPY |
SI23149A (sl) | 2009-09-21 | 2011-03-31 | Silverstone Pharma | Nove benzatinske soli ACE inhibitorjev, postopek za njihovo pripravo in njihova uporaba za zdravljenje kardiovaskularnih bolezni |
WO2011161223A2 (en) | 2010-06-23 | 2011-12-29 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts |
EP2654729B1 (en) | 2010-12-24 | 2016-05-04 | KRKA, d.d., Novo mesto | Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts together with an organic acid |
CA2922536C (en) | 2013-08-28 | 2022-05-03 | Psychemedics Corporation | Integrity testing of hair samples |
RS58120B1 (sr) | 2014-07-31 | 2019-02-28 | Pharmathen Sa | Kompozicija orodisperzibilnog filma koja sadrži enalapril za lečenje hipertenzije kod pedijatrijske populacije |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4830853A (en) * | 1986-10-20 | 1989-05-16 | Warner-Lambert Company | Drug compositions stabilized against oxidation |
US4743450A (en) * | 1987-02-24 | 1988-05-10 | Warner-Lambert Company | Stabilized compositions |
EP0391462A1 (en) * | 1989-04-05 | 1990-10-10 | Janssen Pharmaceutica N.V. | Synergistic compositions containing ketanserin |
-
1991
- 1991-11-25 SI SI9111842A patent/SI9111842A/sl unknown
- 1991-11-25 YU YU184291A patent/YU48602B/sh unknown
-
1992
- 1992-11-23 ES ES92119896T patent/ES2101004T3/es not_active Expired - Lifetime
- 1992-11-23 DK DK92119896.6T patent/DK0545194T3/da active
- 1992-11-23 DE DE69218557T patent/DE69218557T2/de not_active Expired - Lifetime
- 1992-11-23 AT AT92119896T patent/ATE150650T1/de not_active IP Right Cessation
- 1992-11-23 EP EP92119896A patent/EP0545194B1/en not_active Expired - Lifetime
- 1992-11-24 US US07/980,956 patent/US5350582A/en not_active Expired - Fee Related
- 1992-11-24 CA CA002083683A patent/CA2083683C/en not_active Expired - Fee Related
- 1992-12-30 HR HRP-1842/91A patent/HRP921482B1/xx not_active IP Right Cessation
-
1997
- 1997-06-04 GR GR970401299T patent/GR3023655T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0545194A1 (en) | 1993-06-09 |
GR3023655T3 (en) | 1997-09-30 |
DE69218557D1 (de) | 1997-04-30 |
CA2083683C (en) | 2000-09-05 |
ATE150650T1 (de) | 1997-04-15 |
CA2083683A1 (en) | 1993-05-26 |
YU184291A (sh) | 1994-04-05 |
DK0545194T3 (da) | 1997-07-28 |
EP0545194B1 (en) | 1997-03-26 |
HRP921482A2 (en) | 1996-12-31 |
US5350582A (en) | 1994-09-27 |
DE69218557T2 (de) | 1997-11-13 |
YU48602B (sh) | 1998-12-23 |
ES2101004T3 (es) | 1997-07-01 |
SI9111842A (sl) | 1998-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A1OB | Publication of a patent application | ||
AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
PNAN | Change of the applicant name, address/residence |
Owner name: KRKA, TOVARNA ZDRAVIL, D.D., SI |
|
B1PR | Patent granted | ||
ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20011125 Year of fee payment: 11 |
|
PBON | Lapse due to non-payment of renewal fee |
Effective date: 20021126 |