DK0545194T3 - Stabil formulering af enaprilsalt, fremgangsmåde til fremstilling deraf og anvendelse deraf. - Google Patents

Stabil formulering af enaprilsalt, fremgangsmåde til fremstilling deraf og anvendelse deraf.

Info

Publication number
DK0545194T3
DK0545194T3 DK92119896.6T DK92119896T DK0545194T3 DK 0545194 T3 DK0545194 T3 DK 0545194T3 DK 92119896 T DK92119896 T DK 92119896T DK 0545194 T3 DK0545194 T3 DK 0545194T3
Authority
DK
Denmark
Prior art keywords
salt
sodium
stable formulation
chem
formula
Prior art date
Application number
DK92119896.6T
Other languages
English (en)
Inventor
Marjo Merslavic
Jozica Razen
Ales Rotar
Original Assignee
Krka Tovarna Zdravil
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25555813&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0545194(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Krka Tovarna Zdravil filed Critical Krka Tovarna Zdravil
Application granted granted Critical
Publication of DK0545194T3 publication Critical patent/DK0545194T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
DK92119896.6T 1991-11-25 1992-11-23 Stabil formulering af enaprilsalt, fremgangsmåde til fremstilling deraf og anvendelse deraf. DK0545194T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU184291A YU48602B (sh) 1991-11-25 1991-11-25 Postupak za dobijanje stabilne formulacije soli enalaprila

Publications (1)

Publication Number Publication Date
DK0545194T3 true DK0545194T3 (da) 1997-07-28

Family

ID=25555813

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92119896.6T DK0545194T3 (da) 1991-11-25 1992-11-23 Stabil formulering af enaprilsalt, fremgangsmåde til fremstilling deraf og anvendelse deraf.

Country Status (11)

Country Link
US (1) US5350582A (da)
EP (1) EP0545194B1 (da)
AT (1) ATE150650T1 (da)
CA (1) CA2083683C (da)
DE (1) DE69218557T2 (da)
DK (1) DK0545194T3 (da)
ES (1) ES2101004T3 (da)
GR (1) GR3023655T3 (da)
HR (1) HRP921482B1 (da)
SI (1) SI9111842A (da)
YU (1) YU48602B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5562921A (en) * 1994-07-15 1996-10-08 Sherman; Bernard C. Stable solid pharmaceutical compositions containing enalapril maleate
US5573780A (en) * 1995-08-04 1996-11-12 Apotex Usa Inc. Stable solid formulation of enalapril salt and process for preparation thereof
GB9521781D0 (en) * 1995-10-24 1996-01-03 Merck Sharp & Dohme Therapeutic agents
ES2125198B1 (es) * 1997-05-13 1999-11-16 Vita Invest Sa Asociacion a dosis fija de un inhibidor de la enzima convertidora de angiotensina y de un antagonista de los canales de calcio, procedimiento para su preparacion y su utilizacion para el tratamiento de enfermees cardiovasculares.
PL339360A1 (en) * 1998-07-21 2000-12-18 Kaneka Corp Method of crystallising n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanyl-l-proline maleate
NZ333206A (en) 1998-12-08 2000-07-28 Bernard Charles Sherman Solid pharmaceutical compositions comprising a stable magnesium salt of quinapril that acts as a ACE (Angiotensin Converting Enzyme) inhibitor
US6637359B1 (en) * 1998-12-15 2003-10-28 Maritrans Inc. System and method for internally fitting a new inner hull to an existing outer hull to form a rebuilt double hull vessel
US20040157911A1 (en) * 1999-08-31 2004-08-12 Spiridon Spireas Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof
US6764694B1 (en) * 1999-08-31 2004-07-20 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
US6555551B1 (en) 1999-08-31 2003-04-29 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
HU226950B1 (en) * 1999-11-03 2010-03-29 Richter Gedeon Nyrt The magnesium salt of enalapril and antihypertensive pharmaceutical composition containing it
US20030215526A1 (en) * 2002-03-08 2003-11-20 Scott Stofik Stable formulations of angiotensin converting enzyme (ACE) inhibitors
EA011712B1 (ru) * 2004-03-29 2009-04-28 Ле Лаборатуар Сервье Способ производства твёрдой фармацевтической композиции
SI21800A (sl) * 2004-05-14 2005-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek sinteze perindoprila
WO2007058634A1 (en) 2005-11-17 2007-05-24 Diagen Smartno Pri Ljubljani, D.O.O. Stable formulation of amorphous perindopril salts, a process for their preparation, especially industrial preparation, and their use in the therapy of hypertension
SI23149A (sl) 2009-09-21 2011-03-31 Silverstone Pharma Nove benzatinske soli ACE inhibitorjev, postopek za njihovo pripravo in njihova uporaba za zdravljenje kardiovaskularnih bolezni
EA027787B1 (ru) † 2010-06-23 2017-09-29 Крка, Товарна Здравил, Д.Д., Ново Место Пероральные лекарственные формы, содержащие лерканидипин и эналаприл и их фармацевтически приемлемые соли
SI2654729T1 (sl) 2010-12-24 2016-08-31 Krka, D.D., Novo Mesto Homogene farmacevtske oralne dozirne oblike, ki obsegajo lerkanidipin in enalapril ali njune farmacevtsko sprejemljive soli skupaj z organsko kislino
US8986939B1 (en) 2013-08-28 2015-03-24 Psychemedics Corporation Integrity testing of hair samples
WO2016015798A1 (en) 2014-07-31 2016-02-04 Pharmathen S.A. Orodispersible film composition comprising enalapril for the treatment of hypertension in a pediatric population

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4830853A (en) * 1986-10-20 1989-05-16 Warner-Lambert Company Drug compositions stabilized against oxidation
US4743450A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
EP0391462A1 (en) * 1989-04-05 1990-10-10 Janssen Pharmaceutica N.V. Synergistic compositions containing ketanserin

Also Published As

Publication number Publication date
CA2083683C (en) 2000-09-05
GR3023655T3 (en) 1997-09-30
HRP921482B1 (en) 2000-04-30
ES2101004T3 (es) 1997-07-01
EP0545194A1 (en) 1993-06-09
YU48602B (sh) 1998-12-23
DE69218557T2 (de) 1997-11-13
DE69218557D1 (de) 1997-04-30
EP0545194B1 (en) 1997-03-26
CA2083683A1 (en) 1993-05-26
ATE150650T1 (de) 1997-04-15
YU184291A (sh) 1994-04-05
HRP921482A2 (en) 1996-12-31
US5350582A (en) 1994-09-27
SI9111842A (sl) 1998-04-30

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