HRP20220839T1 - Postupak i uređaj za kontinuiranu granulaciju materijala u prahu - Google Patents

Postupak i uređaj za kontinuiranu granulaciju materijala u prahu Download PDF

Info

Publication number
HRP20220839T1
HRP20220839T1 HRP20220839TT HRP20220839T HRP20220839T1 HR P20220839 T1 HRP20220839 T1 HR P20220839T1 HR P20220839T T HRP20220839T T HR P20220839TT HR P20220839 T HRP20220839 T HR P20220839T HR P20220839 T1 HRP20220839 T1 HR P20220839T1
Authority
HR
Croatia
Prior art keywords
processor
steam
granulation
granules
input material
Prior art date
Application number
HRP20220839TT
Other languages
English (en)
Inventor
Radhika GHIKE
Vijay KULKARNI
Indu Bhushan
Himadri Sen
Babu Padmanabhan
Vinay Rao
Original Assignee
Steerlife India Private Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steerlife India Private Limited filed Critical Steerlife India Private Limited
Publication of HRP20220839T1 publication Critical patent/HRP20220839T1/hr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/02—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/28—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using special binding agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/30—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using agents to prevent the granules sticking together; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/30—Mixing; Kneading continuous, with mechanical mixing or kneading devices
    • B29B7/34—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices
    • B29B7/38—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary
    • B29B7/46—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft
    • B29B7/48—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws
    • B29B7/482—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws provided with screw parts in addition to other mixing parts, e.g. paddles, gears, discs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/30—Mixing; Kneading continuous, with mechanical mixing or kneading devices
    • B29B7/34—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices
    • B29B7/38—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary
    • B29B7/46—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft
    • B29B7/48—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws
    • B29B7/482—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws provided with screw parts in addition to other mixing parts, e.g. paddles, gears, discs
    • B29B7/483—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws provided with screw parts in addition to other mixing parts, e.g. paddles, gears, discs the other mixing parts being discs perpendicular to the screw axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/30—Mixing; Kneading continuous, with mechanical mixing or kneading devices
    • B29B7/34—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices
    • B29B7/38—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary
    • B29B7/46—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft
    • B29B7/48—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws
    • B29B7/488—Parts, e.g. casings, sealings; Accessories, e.g. flow controlling or throttling devices
    • B29B7/489—Screws
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/25—Component parts, details or accessories; Auxiliary operations
    • B29C48/36—Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die
    • B29C48/395—Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die using screws surrounded by a cooperating barrel, e.g. single screw extruders
    • B29C48/40—Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die using screws surrounded by a cooperating barrel, e.g. single screw extruders using two or more parallel screws or at least two parallel non-intermeshing screws, e.g. twin screw extruders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/25—Component parts, details or accessories; Auxiliary operations
    • B29C48/36—Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die
    • B29C48/395—Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die using screws surrounded by a cooperating barrel, e.g. single screw extruders
    • B29C48/40—Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die using screws surrounded by a cooperating barrel, e.g. single screw extruders using two or more parallel screws or at least two parallel non-intermeshing screws, e.g. twin screw extruders
    • B29C48/405—Intermeshing co-rotating screws
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/25—Component parts, details or accessories; Auxiliary operations
    • B29C48/92—Measuring, controlling or regulating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B9/00—Making granules
    • B29B9/02—Making granules by dividing preformed material
    • B29B9/06—Making granules by dividing preformed material in the form of filamentary material, e.g. combined with extrusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2948/00—Indexing scheme relating to extrusion moulding
    • B29C2948/92—Measuring, controlling or regulating
    • B29C2948/92504—Controlled parameter
    • B29C2948/9258—Velocity
    • B29C2948/926—Flow or feed rate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2948/00—Indexing scheme relating to extrusion moulding
    • B29C2948/92—Measuring, controlling or regulating
    • B29C2948/92504—Controlled parameter
    • B29C2948/92723—Content, e.g. percentage of humidity, volatiles, contaminants or degassing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
    • B29C48/04—Particle-shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/25—Component parts, details or accessories; Auxiliary operations
    • B29C48/36—Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die
    • B29C48/50—Details of extruders
    • B29C48/505—Screws
    • B29C48/57—Screws provided with kneading disc-like elements, e.g. with oval-shaped elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/25—Component parts, details or accessories; Auxiliary operations
    • B29C48/36—Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die
    • B29C48/50—Details of extruders
    • B29C48/505—Screws
    • B29C48/59—Screws characterised by details of the thread, i.e. the shape of a single thread of the material-feeding screw

Claims (15)

1. Postupak za pripremanje granula u ko-rotirajućem dvostruko vijčanom procesoru, koji obuhvaća: dovođenje ulaznog materijala za granulaciju u procesoru upotrebom jednog ili više dovoda praha; uvođenje pare kao sredstva za aktivaciju granulacije u procesoru; granuliranje ulaznog materijala u prisutnosti pare za formiranje suhih granula; i sakupljanje suhih granula iz zone pražnjenja procesora; pri čemu je brzina dovođenja pare u procesor kontrolirana na temelju brzine dovođenja ulaznog materijala u procesor tako da je para u količini od otprilike 2.5 do 5 posto masenog udjela u odnosu na ulazni materijal dostupna za granulaciju.
2. Postupak prema patentnom zahtjevu 1, pri čemu se ulazni materijal sastoji od barem jednog aktivnog sastojka ili barem jednog veziva.
3. Postupak prema patentnom zahtjevu 1, pri čemu sadržaj vlage granula prikupljen od procesora nije više od 5 posto masenog udjela, spomenuti sadržaj vlage kao određen postupkom “gubitka putem sušenja“ (engl. Loss-on-Drying method) opisanim u opisu patenta.
4. Postupak prema patentnom zahtjevu 1, dalje obuhvaćajući ravnomjerno miješanje, otpuštenih granula iz procesora s upijačem vlage.
5. Postupak prema patentnom zahtjevu 1, dalje obuhvaćajući dodavanje barem jednog upijača vlage u procesor nakon aktivacije granulacije ulaznog materijala s parom i prije sakupljanja granula iz zone pražnjenja procesora.
6. Postupak prema patentnom zahtjevu 4 ili 5, pri čemu je upijač vlage izabran iz skupine koja se sastoji od mikrokristalne celuloze, silicijevog dioksida ili njihove kombinacije.
7. Ko-rotirajući dvostruki vijčani procesor za pripremu granula prema procesu prema bilo kojem prethodnom patentnom zahtjevu, koji obuhvaća: ulaznu zonu koja ima jedan ili više dovoda praha za dovođenje ulaznog materijala u procesor; dovod pare konfiguriran za uvođenje pare kao sredstva za aktivaciju granulacije u procesor; granulacijsku zonu za granuliranje ulaznog materijala u prisutnosti pare za formiranje granula; upravljača konfiguriranog za nadziranje aktivnosti i brzine dovođenja barem jednog od dovoda praha ili dovoda pare tako da je 2.5 do 5 posto masenog udjela pare u odnosu na ulazni materijal dostupan za granulaciju; i zona pražnjenja imajući ne-istiskujući otvor iz kojeg se mogu skupiti granule.
8. Procesor prema patentnom zahtjevu 7, pri čemu je dovod pare smješten u granulacijsku zonu procesora.
9. Procesor prema patentnom zahtjevu 7, dalje obuhvaćajući dovod pomoćnog sredstva za uvođenje najmanje jednog upijača vlage u procesor nizvodno od dovoda pare.
10. Procesor prema patentnom zahtjevu 7, dalje obuhvaćajući zonu distribucije vlage za miješanje barem jednog upijača vlage s granulama iz granulacijske zone za dobivanje granula sa sadržajem vlage ne više od 5 posto masenog udjela, spomenuti sadržaj vlage kao određen postupkom “gubitka putem sušenja“ (engl. Loss-on-Drying method) kao opisano u opisu patenta.
11. Procesor prema patentnom zahtjevu 9, pri čemu je upravitelj konfiguriran za nadzor aktivnosti i brzine dodavanja jednog ili više dovoda praha, dovoda pare ili dovoda pomoćnog sredstva tako da je sadržaj vlage granula dobiven iz zone pražnjenja manji od 5 posto masenog udjela, spomenuti sadržaj vlage kao određen postupkom “gubitka putem sušenja“ (engl. Loss-on-Drying method) kao što je opisano u opisu patenta.
12. Procesor prema patentnom zahtjevu 7, pri čemu je upravitelj konfiguriran za podešavanje razine uvođenja pare u procesor na temelju brzine dovođenja ulaznog materijala u procesor tako da je 2.5 do 5 posto masenog udjela, pare u odnosu na ulazni materijal dostupno za granulaciju.
13. Procesor prema patentnom zahtjevu 7, pri čemu se granulacijska zona sastoji od barem jednog frakcijskog elementa za gnječenje za ravnomjernu raspodjelu pare tijekom granulacije.
14. Procesor prema patentnom zahtjevu 7, pri čemu granulacijska zona obuhvaća ne više od dva para frakcijskih elemenata za gnječenje za ravnomjernu raspodjelu pare tijekom granulacije.
15. Procesor prema patentnom zahtjevu 10, pri čemu zona distribucije vlage obuhvaća jedan par frakcijskih elemenata za gnječenje.
HRP20220839TT 2015-07-31 2016-08-01 Postupak i uređaj za kontinuiranu granulaciju materijala u prahu HRP20220839T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3986CH2015 2015-07-31
EP16832396.2A EP3328603B1 (en) 2015-07-31 2016-08-01 Process and apparatus for continuous granulation of powder material
PCT/IB2016/054616 WO2017021864A1 (en) 2015-07-31 2016-08-01 A process and apparatus for continuous granulation of powder material

Publications (1)

Publication Number Publication Date
HRP20220839T1 true HRP20220839T1 (hr) 2022-10-14

Family

ID=57942493

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20220839TT HRP20220839T1 (hr) 2015-07-31 2016-08-01 Postupak i uređaj za kontinuiranu granulaciju materijala u prahu

Country Status (6)

Country Link
US (2) US10792634B2 (hr)
EP (1) EP3328603B1 (hr)
ES (1) ES2915324T3 (hr)
HR (1) HRP20220839T1 (hr)
PL (1) PL3328603T3 (hr)
WO (1) WO2017021864A1 (hr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3328603T3 (pl) * 2015-07-31 2022-07-25 Steerlife India Private Limited Sposób oraz urządzenie do ciągłej granulacji materiału proszkowego
WO2023012162A1 (en) * 2021-08-03 2023-02-09 Dfe Pharma Gmbh & Co. Kg. Method for preparing co-processed excipient granules

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3636867A1 (de) * 1986-10-30 1988-05-19 Werner & Pfleiderer Verfahren und vorrichtung zum extrudieren eines lebensmittelprodukts
DE4419579A1 (de) * 1994-06-03 1995-12-07 Basf Ag Kunststoffmaterial und Verfahren zu dessen Herstellung
JPH0890556A (ja) * 1994-09-20 1996-04-09 Kanegafuchi Chem Ind Co Ltd オレフィン系樹脂粒子及び予備発泡粒子の製造方法
DE19537114C2 (de) * 1995-10-05 1998-11-12 Bayer Ag Verfahren zur Trocknung von Polymerpulvern und -agglomeraten
US5772721A (en) * 1995-11-21 1998-06-30 Kazemzadeh; Massoud Process for producing odorless organic and semi-organic fertilizer
JP3434418B2 (ja) * 1996-07-24 2003-08-11 東芝機械株式会社 同方向回転２軸押出機による高融点樹脂の脱水システム
US6287496B1 (en) 1997-05-07 2001-09-11 Bene-Tech, Inc. Method of granulating peat using gentle extrusion conditions and viscosified water
US6117451A (en) * 1998-08-25 2000-09-12 Pharmalogix, Inc. Direct compression metformin hydrochloride tablets
DE19962886A1 (de) * 1999-12-24 2001-07-05 Cognis Deutschland Gmbh Tensidgranulate mit verbesserter Auflösegeschwindigkeit
DE10003124A1 (de) * 2000-01-26 2001-08-09 Cognis Deutschland Gmbh Verfahren zur Herstellung von Tensidgranulaten
US6499984B1 (en) * 2000-05-22 2002-12-31 Warner-Lambert Company Continuous production of pharmaceutical granulation
WO2002009919A2 (en) * 2000-07-31 2002-02-07 Babu Padmanabhan Fractional and higher lobed co-rotating twin-screw elements
US6609819B2 (en) * 2001-07-24 2003-08-26 Wenger Mfg Twin screw extruder with conical non-parallel converging screws
US6833096B2 (en) * 2001-08-29 2004-12-21 General Electric Company Method for removing water and other volatile components from polymer powders
ATE464172T1 (de) * 2002-07-11 2010-04-15 Pirelli Verfahren und vorrichtung zur kontinuierlichen herstellung einer elastomermischung
US20060241213A1 (en) * 2002-10-31 2006-10-26 Maurizio Galimberti Crosslinkable Eleastomeric Composition and Method for Preparing the Composition
US7910030B2 (en) 2002-11-26 2011-03-22 Universiteit Gent Process and apparatus for continuous wet granulation of powder material
GB0329439D0 (en) * 2003-12-19 2004-01-28 Quest Int Production of particles
EP1861233A4 (en) * 2005-03-08 2010-10-06 Steer Engineering Private Ltd DOUBLE SCREEN ELEMENTS FOR AN EXTRUDER SYSTEM
US7591974B2 (en) * 2006-01-25 2009-09-22 Absorbent Technologies, Inc. Methods for producing superabsorbent polymers for use in agricultural applications
EP1832281A1 (en) * 2006-03-10 2007-09-12 Abbott GmbH & Co. KG Process for producing a solid dispersion of an active ingredient
US8067047B2 (en) * 2006-06-27 2011-11-29 James Fajt Method and devices for forming articles
CN102549049B (zh) * 2010-07-28 2014-12-10 陶氏环球技术有限责任公司 干磨多糖衍生物的方法
JP5562368B2 (ja) * 2012-03-01 2014-07-30 株式会社日本製鋼所 スクリュ対および該スクリュ対を備えた同方向噛合型二軸スクリュ押出機
JP6077713B2 (ja) * 2013-05-27 2017-02-08 スティールライフ インディア プライベート リミテッド ホットメルト断片化押出機およびプロセス
CN105984110B (zh) * 2015-03-23 2019-10-15 思蒂亚工程私人有限公司 一种用于同向旋转的双螺杆加工设备的元件
PL3328603T3 (pl) * 2015-07-31 2022-07-25 Steerlife India Private Limited Sposób oraz urządzenie do ciągłej granulacji materiału proszkowego
AR108302A1 (es) * 2016-04-22 2018-08-08 Univ Mississippi Granulación en seco con doble husillo para producir formulaciones sólidas
US11247378B2 (en) * 2016-04-22 2022-02-15 Steerlife India Private Limited Processor and a process for granulation of powders

Also Published As

Publication number Publication date
ES2915324T3 (es) 2022-06-21
US10792634B2 (en) 2020-10-06
US20180214835A1 (en) 2018-08-02
EP3328603B1 (en) 2022-04-06
WO2017021864A1 (en) 2017-02-09
PL3328603T3 (pl) 2022-07-25
EP3328603A1 (en) 2018-06-06
EP3328603A4 (en) 2019-01-09
US11850567B2 (en) 2023-12-26
US20210046439A1 (en) 2021-02-18

Similar Documents

Publication Publication Date Title
HRP20220839T1 (hr) Postupak i uređaj za kontinuiranu granulaciju materijala u prahu
CN202336223U (zh) 一种中药生产用喷雾式干燥装置
HK1135109A1 (en) Granulated maltitol for direct compression and method of preparation thereof
CN205082637U (zh) 一种饲料制粒装置
CN203494185U (zh) 离心喷雾干燥器
KR101485590B1 (ko) 저온건조법을 이용한 꿀 분말의 제조방법
CN103976964B (zh) 依托红霉素片及其制备方法
CN205547322U (zh) 一种滚筒式加料机抄料装置
PL423739A1 (pl) Sposób wytwarzania granulowanego nawozu organiczno-wapniowego
CN208481725U (zh) 一种制粒干燥一体化装置
PL424941A1 (pl) Sposób wytwarzania granulatu z odpadu perlitowego
PL423737A1 (pl) Sposób wytwarzania granulowanego nawozu wapniowego
Spandiyarov et al. The pellet mill for feed mix granulation
PL423736A1 (pl) Sposób wytwarzania granulowanego nawozu organiczno-wapniowego
WO2015008207A3 (en) Plant for the granulation of loose material
PL423750A1 (pl) Sposób wytwarzania granulowanego nawozu organiczno-wapniowo-magnezowego
PL423741A1 (pl) Sposób wytwarzania granulowanego nawozu wapniowo-magnezowego
PL423740A1 (pl) Sposób wytwarzania granulowanego nawozu wapniowego
PL424066A1 (pl) Sposób wytwarzania granulowanego nawozu wapniowego
PL423738A1 (pl) Sposób wytwarzania granulowanego nawozu organiczno-wapniowego
PL423743A1 (pl) Sposób wytwarzania granulowanego nawozu wapniowego
PL424078A1 (pl) Sposób wytwarzania granulowanego nawozu organiczno-wapniowego
PL423735A1 (pl) Sposób wytwarzania granulowanego nawozu organiczno-wapniowego
PL423742A1 (pl) Sposób wytwarzania granulowanego nawozu wapniowego
RU2516664C1 (ru) Устройство для гранулирования удобрений