HRP20201703T1 - Liječenje kokcidioze intramuskularnim triazinskim pripravcima - Google Patents
Liječenje kokcidioze intramuskularnim triazinskim pripravcima Download PDFInfo
- Publication number
- HRP20201703T1 HRP20201703T1 HRP20201703TT HRP20201703T HRP20201703T1 HR P20201703 T1 HRP20201703 T1 HR P20201703T1 HR P20201703T T HRP20201703T T HR P20201703TT HR P20201703 T HRP20201703 T HR P20201703T HR P20201703 T1 HRP20201703 T1 HR P20201703T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparation
- use according
- toltrazuril
- coccidiosis
- treatment
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 3
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 title 1
- 208000003495 Coccidiosis Diseases 0.000 title 1
- 206010023076 Isosporiasis Diseases 0.000 title 1
- 238000007918 intramuscular administration Methods 0.000 title 1
- OCINXEZVIIVXFU-UHFFFAOYSA-N 1-methyl-3-[3-methyl-4-[4-(trifluoromethylthio)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione Chemical compound CC1=CC(N2C(N(C)C(=O)NC2=O)=O)=CC=C1OC1=CC=C(SC(F)(F)F)C=C1 OCINXEZVIIVXFU-UHFFFAOYSA-N 0.000 claims 3
- 229960000898 toltrazuril Drugs 0.000 claims 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- 150000004698 iron complex Chemical class 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 241000224483 Coccidia Species 0.000 claims 1
- 241000567229 Isospora Species 0.000 claims 1
- 230000001476 alcoholic effect Effects 0.000 claims 1
- 230000037396 body weight Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 238000010255 intramuscular injection Methods 0.000 claims 1
- 239000007927 intramuscular injection Substances 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 210000004237 neck muscle Anatomy 0.000 claims 1
- 230000003449 preventive effect Effects 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Claims (7)
1. Pripravak koji sadrži između 10 i 30 mg po kg tjelesne težine toltrazurila za uporabu u preventivnom liječenju infekcije kokcidije iz roda Isospora u novorođenčeta do 3 dana stare svinje, naznačen time, da se navedeni sastav daje jednom intramuskularnom injekcijom i pri čemu je pripravak suspenzija.
2. Pripravak za uporabu u skladu s patentnim zahtjevom 1, naznačen time, da se pripravak daje 0-48 sati nakon rođenja.
3. Pripravak za uporabu u skladu s bilo kojim od patentnih zahtjeva 1 ili 2, naznačen time, da se pripravak daje u mišić vrata ili iza uha.
4. Pripravak za uporabu prema bilo kojem od prethodnih zahtjeva, naznačen time, da je to injektibilni pripravak koji sadrže toltrazuril i kompleks željeza, pri čemu navedeni sastav sadrži, u ukupnom volumenu od 0,5 do 2,0 ml, 100-400 mg složeni spoj željeza i 10-120 mg toltrazurila.
5. Pripravak za uporabu prema zahtjevu 4, naznačen time, da je kompleks željeza gleptoferon.
6. Pripravak za uporabu u skladu s bilo kojim od prethodnih zahtjeva, naznačen time, da je vodena i / ili alkoholna suspenzija.
7. Pripravak za uporabu u skladu s bilo kojim od prethodnih zahtjeva, naznačen time, da nadalje sadrži jedan ili više pomoćnih sastojaka.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306547.6A EP2740470A1 (en) | 2012-12-07 | 2012-12-07 | Treatment of Coccidiosis with intramuscular triazine composition |
| EP19180399.8A EP3566695B1 (en) | 2012-12-07 | 2013-12-06 | Treatment of coccidiosis with intramuscular triazine compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20201703T1 true HRP20201703T1 (hr) | 2020-12-25 |
Family
ID=47351541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20201703TT HRP20201703T1 (hr) | 2012-12-07 | 2020-10-22 | Liječenje kokcidioze intramuskularnim triazinskim pripravcima |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20150320756A1 (hr) |
| EP (4) | EP2740470A1 (hr) |
| JP (1) | JP2016501253A (hr) |
| KR (1) | KR102242354B1 (hr) |
| CN (3) | CN112426426A (hr) |
| AU (1) | AU2013353983A1 (hr) |
| BR (1) | BR112015013178A2 (hr) |
| CA (2) | CA3177623A1 (hr) |
| CL (1) | CL2015001564A1 (hr) |
| CY (1) | CY1123596T1 (hr) |
| DK (2) | DK3566695T3 (hr) |
| ES (2) | ES2816525T3 (hr) |
| HR (1) | HRP20201703T1 (hr) |
| HU (1) | HUE051190T2 (hr) |
| MX (2) | MX2015007129A (hr) |
| PH (1) | PH12015501283B1 (hr) |
| PL (2) | PL3566695T3 (hr) |
| PT (1) | PT3566695T (hr) |
| RU (1) | RU2717821C2 (hr) |
| SI (1) | SI3566695T1 (hr) |
| UA (1) | UA115344C2 (hr) |
| WO (1) | WO2014086959A1 (hr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007025908A1 (de) | 2007-06-01 | 2008-12-04 | Bayer Healthcare Ag | Formulierungen enthaltend Triazinone und Eisen |
| EP2740470A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | Treatment of Coccidiosis with intramuscular triazine composition |
| EP2740469A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | New treatments with triazines |
| EP2740492A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | Triazine formulations with a second active ingredient and surfactant(s) |
| EP3578181A1 (en) | 2018-06-05 | 2019-12-11 | Bayer Animal Health GmbH | Formulation for use in the simultaneous treatment of coccidial infections and iron deficiencies |
| EP3578182A1 (en) | 2018-06-05 | 2019-12-11 | Bayer Animal Health GmbH | Formulations containing triazinones and iron with a low amount of free iron ions |
| KR102259950B1 (ko) * | 2021-02-17 | 2021-06-02 | 경상국립대학교산학협력단 | 복합 이온미네랄 용액을 유효성분으로 함유하는 콕시듐증의 예방 또는 개선용 조성물 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1183940A (en) | 1966-10-22 | 1970-03-11 | Fisons Pharmaceuticals Ltd | Ferric Hydroxide Complexes |
| US3970752A (en) * | 1973-03-20 | 1976-07-20 | Bayer Aktiengesellschaft | Coccidiocidal compositions utilizing 1-phenyl-substituted 1,3,5-triazine |
| DE2718799A1 (de) | 1977-04-27 | 1978-11-09 | Bayer Ag | 1-(4-phenoxy-phenyl)-1,3,5-triazin- derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel und wachstumsfoerderer |
| US4493826A (en) | 1982-01-25 | 1985-01-15 | Schering Corporation | Gentamicin-gleptoferron compositions |
| DE3300793A1 (de) | 1983-01-12 | 1984-07-12 | Bayer Ag, 5090 Leverkusen | Coccidiosemittel |
| US5219853A (en) | 1983-01-12 | 1993-06-15 | Bayer Aktiengesellschaft | Agent for coccidiosis |
| DE3516632A1 (de) | 1985-05-09 | 1986-11-13 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 1,3,5-triazintrionen |
| JPH0776524A (ja) * | 1993-07-13 | 1995-03-20 | Takeda Chem Ind Ltd | 動物用抗貧血剤 |
| DE19603984A1 (de) | 1996-02-05 | 1997-08-07 | Bayer Ag | Granulate von Triazinen |
| DE19603954C2 (de) | 1996-02-05 | 2003-04-17 | Wagon Automotive Gmbh | Prallträger für ein Kraftfahrzeug |
| US6470017B1 (en) | 1998-04-21 | 2002-10-22 | Nippon Telegraph And Telephone Corporation | Packet multiplexing apparatus |
| DE19824483A1 (de) | 1998-06-02 | 1999-12-09 | Bayer Ag | Halbfeste wäßrige Zubereitungen für orale Applikation von Toltrazuril-Sulfon |
| EP1119255A4 (en) * | 1998-10-08 | 2009-04-15 | New Ace Res Company | NEW COMPOSITIONS AND METHOD FOR THE PREVENTION AND TREATMENT OF PROTOCOL DISEASES |
| AU4034800A (en) | 1999-10-08 | 2001-04-23 | New Ace Research Company | Novel compositions and methods for prevention and treatment of protozoal disease |
| DE10040174A1 (de) * | 2000-08-17 | 2002-02-28 | Bayer Ag | Verwendung von Triazintrion-Sulfonen zur Bekämpfung von Coccidiosen |
| DE102004042958A1 (de) * | 2004-09-02 | 2006-03-09 | Bayer Healthcare Ag | Neue antiparasitäre Kombination von Wirkstoffen |
| JP4904283B2 (ja) | 2004-12-01 | 2012-03-28 | アキュショット インク | 無針注射器 |
| DK2023981T3 (da) | 2006-06-07 | 2020-04-06 | Acushot Inc | Ladningsmekanisme til en nålefri injektor |
| DE102006038292A1 (de) | 2006-08-16 | 2008-02-21 | Bayer Healthcare Ag | Transdermale Anwendung von Triazinen zur Bekämpfung von Coccidien-Infektionen |
| DE102007025908A1 (de) * | 2007-06-01 | 2008-12-04 | Bayer Healthcare Ag | Formulierungen enthaltend Triazinone und Eisen |
| TW201006515A (en) | 2008-03-07 | 2010-02-16 | Pharmajet Inc | Intradermal injector and uses thereof |
| SI22751A (sl) | 2008-04-03 | 2009-10-31 | Krka, D.D., Novo Mesto | Toltrazuril z izboljĺ animi lastnostmi za raztapljanje |
| US20100257667A1 (en) | 2009-04-10 | 2010-10-14 | James Kennedy | Ventilated Toilet |
| FR2946882B1 (fr) * | 2009-06-18 | 2011-08-26 | Ceva Sante Animale | Suspension veterinaire gelifiee de fer |
| DE102009038949A1 (de) | 2009-08-26 | 2011-03-03 | Bayer Animal Health Gmbh | Neue Verwendung von heterocyclisch substituierten 1,2,4-Triazindionen |
| CN101947201B (zh) | 2010-09-08 | 2011-12-28 | 洛阳惠中兽药有限公司 | 兽药纳米混悬剂及其制备方法与应用 |
| CN102512366A (zh) | 2011-12-28 | 2012-06-27 | 广州市和生堂动物药业有限公司 | 妥曲珠利悬浮乳剂及其制备方法 |
| CN102743334A (zh) * | 2012-07-30 | 2012-10-24 | 郑州后羿制药有限公司 | 一种妥曲珠利注射剂及其制备方法 |
| EP2740469A1 (en) * | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | New treatments with triazines |
| EP2740470A1 (en) | 2012-12-07 | 2014-06-11 | Ceva Sante Animale | Treatment of Coccidiosis with intramuscular triazine composition |
| EP3578181A1 (en) | 2018-06-05 | 2019-12-11 | Bayer Animal Health GmbH | Formulation for use in the simultaneous treatment of coccidial infections and iron deficiencies |
-
2012
- 2012-12-07 EP EP12306547.6A patent/EP2740470A1/en not_active Withdrawn
-
2013
- 2013-12-06 CN CN202011426731.4A patent/CN112426426A/zh active Pending
- 2013-12-06 RU RU2015127023A patent/RU2717821C2/ru active
- 2013-12-06 DK DK19180399.8T patent/DK3566695T3/da active
- 2013-12-06 CN CN202010468261.1A patent/CN111714450A/zh active Pending
- 2013-12-06 KR KR1020157018138A patent/KR102242354B1/ko active IP Right Grant
- 2013-12-06 US US14/650,052 patent/US20150320756A1/en not_active Abandoned
- 2013-12-06 HU HUE19180399A patent/HUE051190T2/hu unknown
- 2013-12-06 PL PL19180399T patent/PL3566695T3/pl unknown
- 2013-12-06 PT PT191803998T patent/PT3566695T/pt unknown
- 2013-12-06 DK DK13815401T patent/DK2928455T3/da active
- 2013-12-06 CN CN201380064038.9A patent/CN104994840A/zh active Pending
- 2013-12-06 WO PCT/EP2013/075757 patent/WO2014086959A1/en active Application Filing
- 2013-12-06 EP EP13815401.8A patent/EP2928455B1/en active Active
- 2013-12-06 PL PL13815401T patent/PL2928455T3/pl unknown
- 2013-12-06 MX MX2015007129A patent/MX2015007129A/es unknown
- 2013-12-06 BR BR112015013178A patent/BR112015013178A2/pt not_active Application Discontinuation
- 2013-12-06 JP JP2015546023A patent/JP2016501253A/ja not_active Withdrawn
- 2013-12-06 ES ES19180399T patent/ES2816525T3/es active Active
- 2013-12-06 EP EP19180399.8A patent/EP3566695B1/en active Active
- 2013-12-06 CA CA3177623A patent/CA3177623A1/en active Pending
- 2013-12-06 AU AU2013353983A patent/AU2013353983A1/en not_active Abandoned
- 2013-12-06 SI SI201331807T patent/SI3566695T1/sl unknown
- 2013-12-06 CA CA2892887A patent/CA2892887C/en active Active
- 2013-12-06 ES ES13815401T patent/ES2761574T3/es active Active
- 2013-12-06 UA UAA201506702A patent/UA115344C2/uk unknown
- 2013-12-06 EP EP20187714.9A patent/EP3747429A1/en active Pending
-
2015
- 2015-06-05 MX MX2021006166A patent/MX2021006166A/es unknown
- 2015-06-05 PH PH12015501283A patent/PH12015501283B1/en unknown
- 2015-06-05 CL CL2015001564A patent/CL2015001564A1/es unknown
-
2020
- 2020-10-19 CY CY20201100985T patent/CY1123596T1/el unknown
- 2020-10-22 HR HRP20201703TT patent/HRP20201703T1/hr unknown
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