HRP20201514T1 - Medicinski proizvod za isporuku s aksijalno izvlačivim pogonskim elementom - Google Patents

Medicinski proizvod za isporuku s aksijalno izvlačivim pogonskim elementom Download PDF

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HRP20201514T1
HRP20201514T1 HRP20201514TT HRP20201514T HRP20201514T1 HR P20201514 T1 HRP20201514 T1 HR P20201514T1 HR P20201514T T HRP20201514T T HR P20201514TT HR P20201514 T HRP20201514 T HR P20201514T HR P20201514 T1 HRP20201514 T1 HR P20201514T1
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drive
drive belt
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defines
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HRP20201514TT
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Jared Alden Judson
Timothy Lee Moulton
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Eli Lilly And Company
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31515—Connection of piston with piston rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31518—Piston or piston-rod constructions, e.g. connection of piston with piston-rod designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M2005/31588—Constructional features or modes of drive mechanisms for piston rods electrically driven

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Surgical Instruments (AREA)

Claims (21)

1. Medicinski proizvod za isporuku (20, 20B, 20C) za primjenu sa spremnikom lijeka (22) koji se sastoji od tijela spremnika (24) u kojem se nalazi lijek (25) i koji određuje izlazni otvor (28), pri čemu spremnik lijeka dodatno sadrži klip (26) postavljen unutar tijela spremnika, a pomicanje klipa u tijelu spremnika istiskuje lijek kroz izlazni otvor; pri čemu proizvod za isporuku uključuje: potpornu konstrukciju (30, 30B) prilagođenu za podupiranje spremnika lijeka (22); i pogonski sklop (32, 32B) koji podupire potporna konstrukcija (30, 30B) i koji je prilagođen da pomiče klip (26) unutar tijela spremnika (24), naznačeno time, što se pogonski sklop sastoji od: pogonsku traku (40, 40B) koja ima distalni rubni dio (56, 56B) i proksimalni rubni dio (58, 58B), pri čemu pogonska traka ima uvučenu konfiguraciju i izvučenu konfiguraciju, naznačeno time, što uvučeni dio (54, 54B) pogonske trake u uvučenoj konfiguraciji određuje spiralu, a izvučeni dio (52, 52B) pogonske trake u izvučenoj konfiguraciji određuje zavojnicu, pri čemu se pogonska traka može pomicati u pomacima između uvučene i izvučene konfiguracije koje određuju pogonsku os (50, 50B); mehanički pogon (38) operativno povezan s pogonskom trakom (40, 40B) koji selektivno okreće pogonsku traku oko pogonske osi (50, 50B), pri čemu okretanje pogonske trake u prvom smjeru izvlači pogonsku traku, a okretanje pogonske trake u suprotnom smjeru uvlači pogonsku traku; potisni element (88, 88B, 88C) operativno postavljen između potporne konstrukcije (30, 30B) i pogonske trake (40, 40B), pri čemu je potisni element zahvaćen s najmanje jednim dijelom (166) proksimalnog rubnog dijela (58, 58B) kada je pogonska traka barem djelomično izvučena; noseći element (80, 80B) koji podupire pogonska traka (40, 40B) u blizini distalnog kraja pogonske trake, pri čemu je noseći element prilagođen da ispoljava aksijalnu silu na klip (26) kada je pogonska traka izvučena; i naznačeno time, što se aksijalna sila koju noseći element (80, 80B) ispoljava na klip (26) barem djelomično prenosi na potpornu konstrukciju (30, 30B) kroz spremnik lijeka (22) i, kada se aksijalno kompresivno opterećenje ispoljava na pogonsku traku (40, 40B), aksijalno kompresivno opterećenje se prenosi na potpornu konstrukciju kroz potisni element (88, 88B, 88C).
2. Proizvod za isporuku prema patentnom zahtjevu 1, naznačen time, što je potisni element (88) rotacijski fiksan u odnosu na potpornu konstrukciju (30) i određuje spiralnu kosinu (90) koja se može zahvatiti s proksimalnim rubnim dijelom (58) pogonske trake (40), naznačeno time, što kada se pogonska traka okreće u prvom smjeru, prijelazni dio (53) pogonske trake koji je zahvaćen sa spiralnom kosinom prelazi iz uvučene konfiguracije u izvučenu konfiguraciju, a kada se pogonska traka okreće u drugom smjeru, prijelazni dio pogonske trake koji je zahvaćen sa spiralnom kosinom prelazi iz izvučene konfiguracije u uvučenu konfiguraciju.
3. Proizvod za isporuku prema patentnom zahtjevu 2, koji dodatno sadrži noseći element trake (100) koji ograničava potisni element (88) koji ispoljava radijalno prema unutra pritisnu silu na pogonsku traku (40) u blizini spiralne kosine (90).
4. Proizvod za isporuku prema patentnom zahtjevu 3, naznačen time, što noseći element trake (100) dodatno sadrži više valjaka (94) koji se mogu zahvatiti s pogonskom trakom (40), pri čemu više valjaka ispoljava silu radijalno prema unutra i pomiče pogonsku traku na spiralnu kosinu (90) potisnog elementa (88) dok se pogonska traka okreće.
5. Proizvod za isporuku prema bilo kojem patentnom zahtjevu od 2 do 4, naznačen time, što noseći element (80) uključuje okretni ležaj (82) koji omogućava relativno okretanje između pogonske trake (40) i klipa (26) oko pogonske osi (50).
6. Proizvod za isporuku prema bilo kojem patentnom zahtjevu od 2 do 4 naznačen time, što, u izvučenom dijelu (52) pogonske trake (40), proksimalni rubni dio (58) pogonske trake je izravno putem ležaja zahvaćen sa susjednim dijelom distalnog rubnog dijela (56).
7. Proizvod za isporuku prema patentnom zahtjevu 6, naznačen time, što jedan proksimalni i distalni rubni dio (56, 58) određuje rub koji se proteže radijalno (60) radi izravnog zahvaćanja putem ležaja s drugim proksimalnim i distalnim rubnim dijelom.
8. Proizvod za isporuku prema patentnom zahtjevu 6, naznačen time, što jedan proksimalni i distalni rubni dio (56, 58) određuje više izbočina (64), a drugi proksimalni i distalni rubni dio određuje više kooperativnih udubljenja (66).
9. Proizvod za isporuku prema patentnom zahtjevu 1, naznačen time, što je pogonska traka (40, 40B) jedinstvena jednodijelna traka, a aksijalne sile koje se prenose između nosećeg elementa (80, 80B) i potisnog elementa (88, 88B, 88C) kada je pogonska traka barem djelomično izvučena, prenose se putem jedinstvene jednodijelne trake.
10. Proizvod za isporuku prema patentnom zahtjevu 1, koji dodatno uključuje cilindričnu bobinu (104, 104B), pri čemu se uvučeni dio (54, 54B) pogonske trake (40, 40B) pohranjuje u bobini, i pri čemu je uvučeni dio (54, 54B) pogonske rake (40, 40B) je postavljen unutar bobine (104, 104B), pri čemu distalna rubna površina (170) pogonske trake leži u prvoj ravnini (110) postavljenoj okomito na pogonsku os (50, 50B), a proksimalna rubna površina (164) pogonske trake leži u prvoj ravnini (112) postavljenoj okomito na pogonsku os.
11. Proizvod za isporuku (20B, 20C) prema patentnom zahtjevu 1, naznačen time, što proksimalni rubni dio (58B) određuje proksimalnu rubnu površinu (164), a distalni rubni dio (56B) određuje distalnu rubnu površinu (170), pri čemu proksimalna rubna površina (164) određuje prvi longitudinalni dio (166) aksijalno usmjeren i drugi longitudinalni dio (168) aksijalno usmjeren, a distalna rubna površina (170) određuje treći longitudinalni dio (172) aksijalno usmjeren i četvrti longitudinalni dio (174) aksijalno usmjeren, a u izvučenom dijelu pogonske osi koja određuje zavojnicu, proksimalni rubni dio (58B) trake je zahvaćen sa susjednim dijelom distalnog rubnog dijela (56B), pri čemu je drugi longitudinalni dio (168) proksimalne rubne površine (164) zahvaćen s trećim longitudinalnim dijelom (172) distalne rubne površine (170), a prvi longitudinalni dio (166) proksimalne rubne površine (164) i četvrti longitudinalni dio (174) distalne rubne površine (170) protežu se radijalno prema van u suprotnom smjerovima; i potisni element (88B, 88C) je zahvaćen s prvim longitudinalnim dijelom (166) proksimalne rubne površine (164).
12. Proizvod za isporuku prema patentnom zahtjevu 11, naznačen time, što se četvrti longitudinalni dio (174) distalne rubne površine (170) proteže radijalno prema van, a prvi longitudinalni dio (166) proksimalne rubne površine (164) proteže se radijalno prema unutra.
13. Proizvod za isporuku prema patentnom zahtjevu 11, naznačen time, što potisni element (88B, 88C) uključuje spiralni navoj (176) koji se može zahvatiti s prvim longitudinalnim dijelom (166) proksimalne rubne površine (164).
14. Proizvod za isporuku prema patentnom zahtjevu 13, naznačen time, što se četvrti longitudinalni dio (174) distalne rubne površine (170) proteže radijalno prema van, a prvi longitudinalni dio (166) proksimalne rubne površine (164) proteže se radijalno prema unutra, a proizvod za isporuku (20B, 20C) dodatno uključuje noseći element trake (100B) koji ograničava pogonsku traku (40B), naznačeno time, što noseći element trake određuje drugi spiralni navoj (178) koji se može zahvatiti s četvrtim longitudinalnim dijelom (174) distalne rubne površine (170).
15. Proizvod za isporuku prema patentnom zahtjevu 14, naznačen time, što se drugi spiralni navoj (178) pruža za više od 360 stupnjeva oko pogonske osi i ograničava pogonsku traku (40B) u blizini potisnog elementa (88B, 88C).
16. Proizvod za isporuku prema patentnom zahtjevu 11, naznačen time, što jedan proksimalni i distalni rubni dio (56B, 58B) određuje više klinova (154), a drugi proksimalni i distalni rub određuje više otvora (156), naznačeno time, što izvučeni dio (52B) pogonske trake (40B) određuje zavojnicu, pri čemu zahvaćanje proksimalnog rubnog dijela pogonske trake sa susjednim dijelom distalnog rubnog dijela uključuje zahvaćanje zatika u otvore.
17. Proizvod za isporuku prema bilo kojem patentnom zahtjevu od 2 do 7 i 16, naznačen time, što pogonska traka (40B) određuje više zubaca (78B) koji se mogu zahvatiti s mehaničkim pogonom (38) pri čemu se mehanički pogon može zahvatiti sa i okretati pogonsku traku prijenosom okretne sile kroz više zubaca.
18. Proizvod za isporuku prema patentnom zahtjevu 17, naznačen time, što mehanički pogon (38) uključuje pužni prijenos (122) koji se može zahvatiti s više zubaca (78, 78B).
19. Proizvod za isporuku prema patentnom zahtjevu 17 kada je ovisan samo o patentnom zahtjevu 16, naznačen time, što pogonska traka (40B) određuje prvu i drugu glavnu površinu (158, 160) na suprotnim stranama pogonske trake, i naznačen time, što se više zatika (154), više otvora (156) i zupci (78B) svi nalaze na prvoj glavnoj površini (158) pogonske trake pri čemu su zatici, otvori i zupci prilagođeni da budu strojno obrađeni sa strane prve glavne površine i naznačen time, što druga glavna površina određuje ravnu površinu.
20. Proizvod za isporuku prema patentnom zahtjevu 19, naznačen time, što je pogonska traka (40B) jedinstvena jednodijelna traka i aksijalne sile koje se prenose između nosećeg elementa (80B) i potisnog elementa (88B, 88C) kada je pogonska traka barem djelomično izvučena prenose se putem jedinstvene jednodijelne trake i, naznačen time, što krajnji dijelovi prve i druge glavne površine (158, 160) određuju ravnine (159, 161) koje su međusobno paralelne i, naznačeno time, što udaljenost (162) između ravni koju određuju prva i druga glavna površina određuje najveću debljinu pogonske trake.
21. Proizvod za isporuku prema patentnom zahtjevu 1 ili patentnom zahtjevu 11, koji dodatno uključuje bobinu (104B) koja se može okretati u odnosu na potisni element (88B), pri čemu se uvučeni dio (54B) pogonske trake (40B) pohranjuje u bobini.
HRP20201514TT 2016-03-21 2020-09-22 Medicinski proizvod za isporuku s aksijalno izvlačivim pogonskim elementom HRP20201514T1 (hr)

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Application Number Priority Date Filing Date Title
US201662310961P 2016-03-21 2016-03-21
EP17714086.0A EP3432948B1 (en) 2016-03-21 2017-03-14 Medical delivery device with axially expandable drive member
PCT/US2017/022259 WO2017165154A1 (en) 2016-03-21 2017-03-14 Medical delivery device with axially expandable drive member

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HRP20201514T1 true HRP20201514T1 (hr) 2020-12-11

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HRP20201514TT HRP20201514T1 (hr) 2016-03-21 2020-09-22 Medicinski proizvod za isporuku s aksijalno izvlačivim pogonskim elementom

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US (3) US10898652B2 (hr)
EP (3) EP3432948B1 (hr)
JP (4) JP6694527B2 (hr)
KR (1) KR102234682B1 (hr)
CN (2) CN113069642B (hr)
AU (2) AU2017237899B2 (hr)
CA (1) CA3018068C (hr)
CY (1) CY1123559T1 (hr)
DK (2) DK3730173T3 (hr)
EA (1) EA035398B1 (hr)
ES (2) ES2968239T3 (hr)
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