HRP20200821T1 - Novi procesi za pripremu vemurafeniba - Google Patents

Novi procesi za pripremu vemurafeniba Download PDF

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Publication number
HRP20200821T1
HRP20200821T1 HRP20200821TT HRP20200821T HRP20200821T1 HR P20200821 T1 HRP20200821 T1 HR P20200821T1 HR P20200821T T HRP20200821T T HR P20200821TT HR P20200821 T HRP20200821 T HR P20200821T HR P20200821 T1 HRP20200821 T1 HR P20200821T1
Authority
HR
Croatia
Prior art keywords
formula
compound
image
process according
reaction
Prior art date
Application number
HRP20200821TT
Other languages
English (en)
Croatian (hr)
Inventor
Antti KATAJA
Original Assignee
Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fermion Oy filed Critical Fermion Oy
Publication of HRP20200821T1 publication Critical patent/HRP20200821T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HRP20200821TT 2016-07-01 2017-06-30 Novi procesi za pripremu vemurafeniba HRP20200821T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FI20165557 2016-07-01
FI20165778 2016-10-12
EP17745368.5A EP3478684B1 (en) 2016-07-01 2017-06-30 New processes for the preparation of vemurafenib
PCT/FI2017/000012 WO2018002415A1 (en) 2016-07-01 2017-06-30 New processes for the preparation of vemurafenib

Publications (1)

Publication Number Publication Date
HRP20200821T1 true HRP20200821T1 (hr) 2020-08-07

Family

ID=59416718

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20200821TT HRP20200821T1 (hr) 2016-07-01 2017-06-30 Novi procesi za pripremu vemurafeniba

Country Status (10)

Country Link
US (1) US10407427B2 (https=)
EP (1) EP3478684B1 (https=)
JP (1) JP6911062B2 (https=)
CA (1) CA3029361A1 (https=)
ES (1) ES2802476T3 (https=)
HR (1) HRP20200821T1 (https=)
HU (1) HUE049682T2 (https=)
PL (1) PL3478684T3 (https=)
RS (1) RS60451B1 (https=)
WO (1) WO2018002415A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2928773T3 (es) 2017-01-17 2022-11-22 Heparegenix Gmbh Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos
US12599591B2 (en) 2018-10-03 2026-04-14 Jyväskylän Yliopisto Vemurafenib and salts thereof for use in the treatment of enteroviral infections

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303759B1 (it) * 1998-11-17 2001-02-23 Dompe Spa Procedimento migliorato per la preparazione di acido 7-azaindolil-3-carbossilico.
UA95244C2 (ru) 2005-06-22 2011-07-25 Плексикон, Инк. Соединения и способ модулирования активности киназ, и показания для их применения
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
US8779150B2 (en) 2010-07-21 2014-07-15 Hoffmann-La Roche Inc. Processes for the manufacture of propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1 H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide
JP2016512518A (ja) 2013-03-14 2016-04-28 ラシオファルム ゲーエムベーハー ベムラフェニブ塩酸塩の固体形態
WO2015075749A1 (en) 2013-11-22 2015-05-28 Laurus Labs Private Limited Novel processes for the preparation of vemurafenib
CZ2013943A3 (cs) 2013-11-27 2015-06-03 Zentiva, K.S. Krystalické formy vemurafenibu
US10414764B2 (en) 2014-11-29 2019-09-17 Shilpa Medicare Limited Substantially pure vemurafenib and its salts

Also Published As

Publication number Publication date
ES2802476T3 (es) 2021-01-19
RS60451B1 (sr) 2020-07-31
EP3478684B1 (en) 2020-04-15
JP2019522662A (ja) 2019-08-15
US20190194197A1 (en) 2019-06-27
HUE049682T2 (hu) 2020-10-28
CA3029361A1 (en) 2018-01-04
WO2018002415A1 (en) 2018-01-04
EP3478684A1 (en) 2019-05-08
JP6911062B2 (ja) 2021-07-28
PL3478684T3 (pl) 2020-08-10
US10407427B2 (en) 2019-09-10

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