HRP20200504T1 - Lokalni preparati farmaceutskih i medicinskih proizvoda koji sadrže kombinacije sukralfata, hijaluronske kiseline, arginina i prirodnog hidratantnog sredstva - Google Patents
Lokalni preparati farmaceutskih i medicinskih proizvoda koji sadrže kombinacije sukralfata, hijaluronske kiseline, arginina i prirodnog hidratantnog sredstva Download PDFInfo
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- HRP20200504T1 HRP20200504T1 HRP20200504TT HRP20200504T HRP20200504T1 HR P20200504 T1 HRP20200504 T1 HR P20200504T1 HR P20200504T T HRP20200504T T HR P20200504TT HR P20200504 T HRP20200504 T HR P20200504T HR P20200504 T1 HRP20200504 T1 HR P20200504T1
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- 238000002360 preparation method Methods 0.000 title claims 23
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title claims 4
- 229920002674 hyaluronan Polymers 0.000 title claims 4
- 229960003160 hyaluronic acid Drugs 0.000 title claims 4
- MNQYNQBOVCBZIQ-JQOFMKNESA-A sucralfate Chemical compound O[Al](O)OS(=O)(=O)O[C@@H]1[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](COS(=O)(=O)O[Al](O)O)O[C@H]1O[C@@]1(COS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)O1 MNQYNQBOVCBZIQ-JQOFMKNESA-A 0.000 title claims 3
- 229960004291 sucralfate Drugs 0.000 title claims 3
- 239000004475 Arginine Substances 0.000 title 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 title 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 title 1
- 229960003121 arginine Drugs 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 230000003020 moisturizing effect Effects 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 claims 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims 2
- 229930064664 L-arginine Natural products 0.000 claims 2
- 235000014852 L-arginine Nutrition 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 235000012907 honey Nutrition 0.000 claims 2
- 235000013618 yogurt Nutrition 0.000 claims 2
- WCDDVEOXEIYWFB-VXORFPGASA-N (2s,3s,4r,5r,6r)-3-[(2s,3r,5s,6r)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O)[C@H](O)[C@H]1O WCDDVEOXEIYWFB-VXORFPGASA-N 0.000 claims 1
- 229920002385 Sodium hyaluronate Polymers 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 239000006172 buffering agent Substances 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 239000003974 emollient agent Substances 0.000 claims 1
- 238000000855 fermentation Methods 0.000 claims 1
- 230000004151 fermentation Effects 0.000 claims 1
- 239000002085 irritant Substances 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 239000003961 penetration enhancing agent Substances 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229940010747 sodium hyaluronate Drugs 0.000 claims 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000002562 thickening agent Substances 0.000 claims 1
- 239000000080 wetting agent Substances 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/986—Milk; Derivatives thereof, e.g. butter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Claims (13)
1. Lokalni farmaceutski preparat sadrži, na temelju ukupne mase pripravka:
(A) 0.05-5.0 mas.% sukralfata,
(B) 0.05-5.0 mas.% hijaluronske kiseline ili njene hijaluronatne soli,
(C) 0.05-5.0 mas.% prirodnog jogurta ili derivata jogurta ili proizvoda fermentacije mlijeka ili od meda ili proizvoda od meda ili njihovih mješavina,
(D) 0.05-5.0 mas.% L-arginina,
(E) 80.0-98.0 mas.% vode, i
(F) 1.0-15.0 mas.% nosača ili vozila, osim vode.
2. Preparat prema zahtjevu 1,
naznačen time što je ukupna količina (a) sukralfata poželjno 0.1-2.0 mas.% u odnosu na ukupnu masu pripravka.
3. Preparat prema zahtjevu 1,
naznačen time što je ukupna količina (b) hijaluronske kiseline, njene soli ili njihove mješavine od 0.1-2.0 mas.%, u odnosu na ukupnu masu pripravka.
4. Preparat prema zahtjevu 1,
naznačen time što je ukupna količina (c) u rasponu od 1.0 do 4.0 mas.%, u odnosu na ukupnu masu pripravka.
5. Preparat prema zahtjevu 1,
naznačen time što je ukupna količina (d) L-arginina 0.1-2.0 mas.%, u odnosu na ukupnu masu pripravka.
6. Preparat prema zahtjevu 1,
naznačen time što je ukupna količina (e) vode u rasponu od 90.0 do 98.0 mas.%, u odnosu na ukupnu masu pripravka.
7. Preparat prema zahtjevu 1,
naznačen time što je ukupna količina (f) nosača ili vozila, osim vode, u rasponu od 3.0 do 15.0 mas.%, u odnosu na ukupnu masu pripravka.
8. Preparat prema bilo kojem od gore spomenutih zahtjeva,
naznačen time što je komponenta (b) hijaluronska kiselina ili natrijev hijaluronat ili njihove mješavine.
9. Preparat prema bilo kojem od gore spomenutih zahtjeva,
naznačen time što pripravak nadalje sadrži (g) konzervans.
10. Preparat prema bilo kojem od gore spomenutih zahtjeva,
naznačen time što pripravak nadalje sadrži sredstva protiv nadraživanja, antioksidante, puferirajuća sredstva, kelatna sredstva, emolijense, sredstva za pojačavanje penetracije, sredstva za otapanje, sredstva za zgušnjavanje, sredstva za vlaženje ili njihove mješavine.
11. Preparat prema bilo kojem od gore spomenutih zahtjeva,
naznačen time što pripravak ima pH vrijednost u rasponu od 3.0 do 9.0.
12. Preparat prema bilo kojem od gore spomenutih zahtjeva,
naznačen time što je pripravak formuliran u gel.
13. Preparat kako je definirano u bilo kojem od zahtjeva 1 do 12,
za uporabu u liječenju ili sprječavanju poremećaja ili bolesti kože ili usne šupljine.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20130100323A GR1008308B (el) | 2013-05-31 | 2013-05-31 | Τοπικες φαρμακευτικες και ιατροτεχνολογικες συνθεσεις που περιεχουν συνδυασμους σουκραλφατης, υαλουρονικου οξεος, αργινινης και ενος φυσικου ενυδατικου παραγοντα |
| EP14386014.6A EP2810641B1 (en) | 2013-05-31 | 2014-05-30 | Topical pharmaceutical and medical device preparations containing combinations of sucralfate, hyaluronic acid, arginine and a natural moisturizing agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20200504T1 true HRP20200504T1 (hr) | 2020-08-07 |
Family
ID=51942536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20200504TT HRP20200504T1 (hr) | 2013-05-31 | 2020-03-27 | Lokalni preparati farmaceutskih i medicinskih proizvoda koji sadrže kombinacije sukralfata, hijaluronske kiseline, arginina i prirodnog hidratantnog sredstva |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2810641B1 (hr) |
| CY (1) | CY1122961T1 (hr) |
| GR (1) | GR1008308B (hr) |
| HR (1) | HRP20200504T1 (hr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113038935A (zh) * | 2018-10-10 | 2021-06-25 | 霍利斯特公司 | 含有皮肤愈合成分的造口粉 |
| KR20240015803A (ko) * | 2022-07-27 | 2024-02-06 | 주식회사 현대바이오랜드 | 수크랄페이트를 포함하는 피부 재생용 화장료 조성물 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US591688A (en) | 1897-10-12 | Bottle | ||
| JPS5978116A (ja) | 1982-10-27 | 1984-05-04 | Chugai Pharmaceut Co Ltd | スクラルフェ−ト製剤 |
| CA1218601A (en) | 1983-09-02 | 1987-03-03 | Angel B. Casillan | Sucralfate suspension |
| DE3430809A1 (de) | 1984-08-22 | 1986-03-06 | Merck Patent Gmbh, 6100 Darmstadt | Sucralfat-suspension |
| IT1203901B (it) | 1987-04-15 | 1989-02-23 | Lisapharma Spa | Composizioni farmaceutiche sotto forma di sospensioni stabili di sucralfato esenti da agenti sospendenti |
| GB8713747D0 (en) | 1987-06-12 | 1987-07-15 | Unilever Plc | Skin treatment composition |
| US5908836A (en) | 1987-12-21 | 1999-06-01 | Bar-Shalom; Daniel | Protecting skin from radiation damage using sulphated sugars |
| US5709873A (en) | 1988-02-26 | 1998-01-20 | Niels Bukh A/S | Method of treating conditions of teeth and their supporting tissue |
| DK505588D0 (da) | 1988-02-26 | 1988-09-09 | Jesper Hamburger | Middel og anvendelse af samme |
| US4918175A (en) | 1988-06-21 | 1990-04-17 | Marion Laboratories, Inc. | Bismuth (phosph/sulf)ated saccharides |
| US4975281A (en) | 1989-01-30 | 1990-12-04 | E. R. Squibb & Sons, Inc. | Anti-ulcer composition |
| US5618798A (en) | 1989-04-20 | 1997-04-08 | Bar-Shalom; Daniel | Use of sucralfate to treat baldness |
| CA1340994C (en) | 1989-09-21 | 2000-05-16 | Rudolf Edgar Dr. Falk | Treatment of conditions and disease |
| CA2020200A1 (en) * | 1990-06-29 | 1991-12-30 | Daniel Bar-Shalom | Use of sucralfate |
| US5639738A (en) | 1992-02-20 | 1997-06-17 | Hyal Pharmaceutical Corporation | Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs |
| US5792753A (en) | 1991-07-03 | 1998-08-11 | Hyal Pharmaceutical Corporation | Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs |
| US5425954A (en) | 1993-09-30 | 1995-06-20 | Curafas Incorporated | Topical amino acid - vitamin complex compositions for pharmaceutical and cosmetic use |
| KR19980703526A (ko) | 1995-04-03 | 1998-11-05 | 나가야마오사무 | 수크랄페이트 함유 제제 조성물 |
| US6207713B1 (en) | 1997-09-17 | 2001-03-27 | Eric T. Fossel | Topical and oral delivery of arginine to cause beneficial effects |
| IT1301994B1 (it) * | 1998-08-05 | 2000-07-20 | Jasper Ltd Liability Co | Derivati dell'acido ialuronico. |
| ITMI20041550A1 (it) | 2004-07-29 | 2004-10-29 | Proge Farm Srl | Uso di batteri probiotici per la preparazione di composizioni topiche per la protezione dell'epidermide |
| ITMI20052035A1 (it) | 2005-10-26 | 2007-04-27 | Professional Dietetics Srl | Composizioni farmaceutiche cicatrizzanti sotto forma di crema a base di amminoacidi e sodio ialuronato |
| JP4800015B2 (ja) | 2005-11-22 | 2011-10-26 | 株式会社カロッツェリアジャパン | 皮膚炎発症抑制のための微生物培養物並びにそれらを用いた製品 |
| US7666859B2 (en) * | 2006-09-08 | 2010-02-23 | Norman Turkowitz | Skin compositions containing hydrocortisone |
| CA2639525A1 (en) * | 2008-09-16 | 2010-03-16 | Fayek Todary Michael | Topical composition for the protection and/or treatment of radiation related skin damages |
| ITMI20110033A1 (it) | 2011-01-17 | 2012-07-18 | Biofarmitalia Spa | Composizione terapeutica mucoadesiva a base di acido ialuronico per la prevenzione e terapia di lesioni epiteliali, delle mucose del corpo umano |
| ES2702490T3 (es) | 2011-05-03 | 2019-03-01 | Dupont Nutrition Biosci Aps | Bacterias probióticas para el tratamiento tópico de trastornos de la piel |
-
2013
- 2013-05-31 GR GR20130100323A patent/GR1008308B/el active IP Right Grant
-
2014
- 2014-05-30 EP EP14386014.6A patent/EP2810641B1/en active Active
-
2020
- 2020-03-27 HR HRP20200504TT patent/HRP20200504T1/hr unknown
- 2020-03-31 CY CY20201100308T patent/CY1122961T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR1008308B (el) | 2014-10-02 |
| CY1122961T1 (el) | 2021-10-29 |
| EP2810641B1 (en) | 2020-02-26 |
| EP2810641A1 (en) | 2014-12-10 |
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