CY1122961T1 - Τοπικα φαρμακευτικα και ιατροτεχνολογικα παρασκευασματα που περιεχουν συνδυασμους σουκραλφατης, υαλουρονικου οξεος, αργινινης και ενος φυσικου υγραντικου παραγοντα - Google Patents
Τοπικα φαρμακευτικα και ιατροτεχνολογικα παρασκευασματα που περιεχουν συνδυασμους σουκραλφατης, υαλουρονικου οξεος, αργινινης και ενος φυσικου υγραντικου παραγονταInfo
- Publication number
- CY1122961T1 CY1122961T1 CY20201100308T CY201100308T CY1122961T1 CY 1122961 T1 CY1122961 T1 CY 1122961T1 CY 20201100308 T CY20201100308 T CY 20201100308T CY 201100308 T CY201100308 T CY 201100308T CY 1122961 T1 CY1122961 T1 CY 1122961T1
- Authority
- CY
- Cyprus
- Prior art keywords
- weight
- arginine
- hyaluronic acid
- preparations containing
- sucralphate
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 2
- 229920002674 hyaluronan Polymers 0.000 title abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 239000004475 Arginine Substances 0.000 title 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 title 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 230000003020 moisturizing effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 235000012907 honey Nutrition 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 235000013618 yogurt Nutrition 0.000 abstract 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 1
- 229930064664 L-arginine Natural products 0.000 abstract 1
- 235000014852 L-arginine Nutrition 0.000 abstract 1
- 235000014048 cultured milk product Nutrition 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 239000003906 humectant Substances 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 231100000444 skin lesion Toxicity 0.000 abstract 1
- 206010040882 skin lesion Diseases 0.000 abstract 1
- MNQYNQBOVCBZIQ-JQOFMKNESA-A sucralfate Chemical compound O[Al](O)OS(=O)(=O)O[C@@H]1[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](COS(=O)(=O)O[Al](O)O)O[C@H]1O[C@@]1(COS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)O1 MNQYNQBOVCBZIQ-JQOFMKNESA-A 0.000 abstract 1
- 229960004291 sucralfate Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/986—Milk; Derivatives thereof, e.g. butter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Η παρούσα αίτηση αφορά τοπικά παρασκευάσματα που περιέχουν με βάση το συνολικό βάρος της σύνθεσης: (Α) 0.05-5.0 % κατά βάρος σουκραλφάτη, (Β) 0.05-5.0 % κατά βάρος υαλουρονικό οξύ ή υαλουρονικό άλας αυτού, (C) 0.05-5.0 % κατά βάρος έναν φυσικό υγραντικό παράγοντα, π.χ., φυσικό γιαούρτι ή παράγωγα γιαουρτιού ή προϊόντα ζύμωσης γάλακτος ή μέλι ή προϊόντα μελιού ή μείγματα αυτών, (D) 0.05-5.0 % κατά βάρος L-Αργινίνη, (Ε) 80.0-98.0 % κατά βάρος νερό, και (F) 1.0-15.0 % κατά βάρος έναν μεταφορέα ή φορέα, άλλο από νερό. Τα παρασκευάσματα αυτά είναι σταθερά και δείχνουν ρεοολογικές ιδιότητες συγκρίσιμες με αυτές των συνθέσεων οι οποίες βρίσκονται ήδη στην αγορά για παρόμοιες χρήσεις, ενώ ο χρόνος επούλωσης είναι συντομότερος ή/και η κάθαρση των αλλοιώσεων του δέρματος είναι ενός υψηλότερου βαθμού και ως εκ τούτου οι συνδυασμοί αυτοί είναι χρήσιμοι στη θεραπεία νόσων ή διαταραχών του δέρματος ή της στοματικής κοιλότητας.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20130100323A GR1008308B (el) | 2013-05-31 | 2013-05-31 | Τοπικες φαρμακευτικες και ιατροτεχνολογικες συνθεσεις που περιεχουν συνδυασμους σουκραλφατης, υαλουρονικου οξεος, αργινινης και ενος φυσικου ενυδατικου παραγοντα |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1122961T1 true CY1122961T1 (el) | 2021-10-29 |
Family
ID=51942536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20201100308T CY1122961T1 (el) | 2013-05-31 | 2020-03-31 | Τοπικα φαρμακευτικα και ιατροτεχνολογικα παρασκευασματα που περιεχουν συνδυασμους σουκραλφατης, υαλουρονικου οξεος, αργινινης και ενος φυσικου υγραντικου παραγοντα |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2810641B1 (el) |
| CY (1) | CY1122961T1 (el) |
| GR (1) | GR1008308B (el) |
| HR (1) | HRP20200504T1 (el) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3115754A1 (en) * | 2018-10-10 | 2020-04-16 | Hollister Incorporated | Stoma powder including skin health ingredients |
| KR20240015803A (ko) * | 2022-07-27 | 2024-02-06 | 주식회사 현대바이오랜드 | 수크랄페이트를 포함하는 피부 재생용 화장료 조성물 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US591688A (en) | 1897-10-12 | Bottle | ||
| JPS5978116A (ja) | 1982-10-27 | 1984-05-04 | Chugai Pharmaceut Co Ltd | スクラルフェ−ト製剤 |
| CA1218601A (en) | 1983-09-02 | 1987-03-03 | Angel B. Casillan | Sucralfate suspension |
| DE3430809A1 (de) | 1984-08-22 | 1986-03-06 | Merck Patent Gmbh, 6100 Darmstadt | Sucralfat-suspension |
| IT1203901B (it) | 1987-04-15 | 1989-02-23 | Lisapharma Spa | Composizioni farmaceutiche sotto forma di sospensioni stabili di sucralfato esenti da agenti sospendenti |
| GB8713747D0 (en) | 1987-06-12 | 1987-07-15 | Unilever Plc | Skin treatment composition |
| US5908836A (en) | 1987-12-21 | 1999-06-01 | Bar-Shalom; Daniel | Protecting skin from radiation damage using sulphated sugars |
| DK505588D0 (da) | 1988-02-26 | 1988-09-09 | Jesper Hamburger | Middel og anvendelse af samme |
| US5709873A (en) | 1988-02-26 | 1998-01-20 | Niels Bukh A/S | Method of treating conditions of teeth and their supporting tissue |
| US4918175A (en) | 1988-06-21 | 1990-04-17 | Marion Laboratories, Inc. | Bismuth (phosph/sulf)ated saccharides |
| US4975281A (en) | 1989-01-30 | 1990-12-04 | E. R. Squibb & Sons, Inc. | Anti-ulcer composition |
| US5618798A (en) | 1989-04-20 | 1997-04-08 | Bar-Shalom; Daniel | Use of sucralfate to treat baldness |
| CA1340994C (en) | 1989-09-21 | 2000-05-16 | Rudolf Edgar Dr. Falk | Treatment of conditions and disease |
| CA2020200A1 (en) * | 1990-06-29 | 1991-12-30 | Daniel Bar-Shalom | Use of sucralfate |
| US5639738A (en) | 1992-02-20 | 1997-06-17 | Hyal Pharmaceutical Corporation | Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs |
| US5792753A (en) | 1991-07-03 | 1998-08-11 | Hyal Pharmaceutical Corporation | Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs |
| US5425954A (en) | 1993-09-30 | 1995-06-20 | Curafas Incorporated | Topical amino acid - vitamin complex compositions for pharmaceutical and cosmetic use |
| TR199701092T1 (xx) | 1995-04-03 | 1998-01-21 | Chugai Seiyaku Kabushiki Kaisha Et Al | Sukralfat içeren farmakotik kompozisyonlar. |
| US6207713B1 (en) | 1997-09-17 | 2001-03-27 | Eric T. Fossel | Topical and oral delivery of arginine to cause beneficial effects |
| IT1301994B1 (it) * | 1998-08-05 | 2000-07-20 | Jasper Ltd Liability Co | Derivati dell'acido ialuronico. |
| ITMI20041550A1 (it) | 2004-07-29 | 2004-10-29 | Proge Farm Srl | Uso di batteri probiotici per la preparazione di composizioni topiche per la protezione dell'epidermide |
| ITMI20052035A1 (it) | 2005-10-26 | 2007-04-27 | Professional Dietetics Srl | Composizioni farmaceutiche cicatrizzanti sotto forma di crema a base di amminoacidi e sodio ialuronato |
| JP4800015B2 (ja) | 2005-11-22 | 2011-10-26 | 株式会社カロッツェリアジャパン | 皮膚炎発症抑制のための微生物培養物並びにそれらを用いた製品 |
| US7666859B2 (en) * | 2006-09-08 | 2010-02-23 | Norman Turkowitz | Skin compositions containing hydrocortisone |
| CA2639525A1 (en) * | 2008-09-16 | 2010-03-16 | Fayek Todary Michael | Topical composition for the protection and/or treatment of radiation related skin damages |
| ITMI20110033A1 (it) | 2011-01-17 | 2012-07-18 | Biofarmitalia Spa | Composizione terapeutica mucoadesiva a base di acido ialuronico per la prevenzione e terapia di lesioni epiteliali, delle mucose del corpo umano |
| DK2704704T3 (en) | 2011-05-03 | 2019-01-14 | Dupont Nutrition Biosci Aps | PROBIOTIC BACTERIES FOR TOPICAL TREATMENT OF SKIN DISORDERS |
-
2013
- 2013-05-31 GR GR20130100323A patent/GR1008308B/el active IP Right Grant
-
2014
- 2014-05-30 EP EP14386014.6A patent/EP2810641B1/en active Active
-
2020
- 2020-03-27 HR HRP20200504TT patent/HRP20200504T1/hr unknown
- 2020-03-31 CY CY20201100308T patent/CY1122961T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR1008308B (el) | 2014-10-02 |
| EP2810641B1 (en) | 2020-02-26 |
| EP2810641A1 (en) | 2014-12-10 |
| HRP20200504T1 (hr) | 2020-08-07 |
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