BR112015008964A2 - composições injetáveis estáveis contendo diclofenaco e tiocolquicosídeo - Google Patents

composições injetáveis estáveis contendo diclofenaco e tiocolquicosídeo

Info

Publication number
BR112015008964A2
BR112015008964A2 BR112015008964A BR112015008964A BR112015008964A2 BR 112015008964 A2 BR112015008964 A2 BR 112015008964A2 BR 112015008964 A BR112015008964 A BR 112015008964A BR 112015008964 A BR112015008964 A BR 112015008964A BR 112015008964 A2 BR112015008964 A2 BR 112015008964A2
Authority
BR
Brazil
Prior art keywords
thiocolchicoside
containing diclofenac
stable injectable
compositions containing
injectable compositions
Prior art date
Application number
BR112015008964A
Other languages
English (en)
Inventor
Macelloni Cristina
Irianni Giuseppe
Teseschi Luca
Original Assignee
Epifarma S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epifarma S R L filed Critical Epifarma S R L
Publication of BR112015008964A2 publication Critical patent/BR112015008964A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Abstract

resumo patente de invenção: "composição injetável estável contendo diclofenaco e tiocolquicosídeo". a presente invenção refere-se a uma solução aquosa injetável estável contendo diclofenaco e tiocolquicosídeo, ou seus sais farmaceuticamente aceitáveis, e o seu uso no tratamento de condições dolorosas e inflamatórias, reumáticas ou traumáticas das juntas, músculos, tendões e ligamentos.
BR112015008964A 2012-10-22 2013-10-21 composições injetáveis estáveis contendo diclofenaco e tiocolquicosídeo BR112015008964A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001782A ITMI20121782A1 (it) 2012-10-22 2012-10-22 Composizione iniettabile stabile contenente diclofenac e tiocolchicoside
PCT/EP2013/071925 WO2014064030A1 (en) 2012-10-22 2013-10-21 Stable injectable composition containing diclofenac and thiocolchicoside

Publications (1)

Publication Number Publication Date
BR112015008964A2 true BR112015008964A2 (pt) 2017-07-04

Family

ID=47425217

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015008964A BR112015008964A2 (pt) 2012-10-22 2013-10-21 composições injetáveis estáveis contendo diclofenaco e tiocolquicosídeo

Country Status (15)

Country Link
US (1) US9427446B2 (pt)
EP (1) EP2908801B1 (pt)
JP (1) JP2015534971A (pt)
KR (1) KR20150082224A (pt)
CN (1) CN104853743A (pt)
BR (1) BR112015008964A2 (pt)
CA (1) CA2888823A1 (pt)
HK (1) HK1213977A1 (pt)
IT (1) ITMI20121782A1 (pt)
MA (1) MA38016A1 (pt)
MX (1) MX2015004962A (pt)
RU (1) RU2666993C2 (pt)
TN (1) TN2015000150A1 (pt)
WO (1) WO2014064030A1 (pt)
ZA (1) ZA201502646B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11110073B2 (en) 2017-03-24 2021-09-07 Cadila Healthcare Limited Storage stable aqueous injectable solution comprising diclofenac
GR1009729B (el) 2018-08-02 2020-05-15 Win Medica Φαρμακευτικη Ανωνυμη Εταιρεια Σταθερος ενεσιμος συνδυασμος
US11707443B2 (en) 2019-09-26 2023-07-25 Rk Pharma Inc. Storage stable aqueous parenteral solutions comprising diclofenac

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3446873A1 (de) 1984-12-21 1986-07-10 Merckle Gmbh Fluessige diclofenac-zubereitungen
FR2735369B1 (fr) * 1995-06-13 1997-07-11 Synthelabo Compositions pharmaceutiques a base de sel de sodium du diclofenac et de thiocolchicoside
CN1210463A (zh) * 1996-02-07 1999-03-10 株式会社津村 透明双氯芬酸钠的水溶液以及它的药物组合物
WO2009092819A1 (en) * 2008-01-25 2009-07-30 Duo-Ge Combination of oral medicaments bonded by a wrapping
WO2012053012A2 (en) * 2010-10-21 2012-04-26 Cadila Healthcare Limited Topical pharmaceutical compositions comprising tfflocolchicoside

Also Published As

Publication number Publication date
RU2666993C2 (ru) 2018-09-13
KR20150082224A (ko) 2015-07-15
MX2015004962A (es) 2015-07-06
ITMI20121782A1 (it) 2014-04-23
MA38016A1 (fr) 2016-12-30
US20150238510A1 (en) 2015-08-27
EP2908801A1 (en) 2015-08-26
CA2888823A1 (en) 2014-05-01
US9427446B2 (en) 2016-08-30
CN104853743A (zh) 2015-08-19
RU2015114709A (ru) 2016-11-10
EP2908801B1 (en) 2020-09-16
JP2015534971A (ja) 2015-12-07
WO2014064030A1 (en) 2014-05-01
HK1213977A1 (zh) 2016-07-15
ZA201502646B (en) 2016-08-31
TN2015000150A1 (en) 2016-10-03

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2433 DE 22-08-2017 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.