HRP20200351T1 - Cikloalkinski derivati saharida - Google Patents
Cikloalkinski derivati saharida Download PDFInfo
- Publication number
- HRP20200351T1 HRP20200351T1 HRP20200351TT HRP20200351T HRP20200351T1 HR P20200351 T1 HRP20200351 T1 HR P20200351T1 HR P20200351T T HRP20200351T T HR P20200351TT HR P20200351 T HRP20200351 T HR P20200351T HR P20200351 T1 HRP20200351 T1 HR P20200351T1
- Authority
- HR
- Croatia
- Prior art keywords
- saccharide
- conjugate
- group
- azide
- spacer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1300707.5A GB201300707D0 (en) | 2013-01-15 | 2013-01-15 | Compounds and processes |
| PCT/EP2014/050483 WO2014111344A1 (en) | 2013-01-15 | 2014-01-13 | Cycloalkyne derivatized saccharides |
| EP14700602.7A EP2945641B1 (en) | 2013-01-15 | 2014-01-13 | Cycloalkyne derivatized saccharides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20200351T1 true HRP20200351T1 (hr) | 2020-06-12 |
Family
ID=47758014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20200351TT HRP20200351T1 (hr) | 2013-01-15 | 2014-01-13 | Cikloalkinski derivati saharida |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11135300B2 (enExample) |
| EP (1) | EP2945641B1 (enExample) |
| JP (3) | JP6719209B2 (enExample) |
| CN (1) | CN105377282B (enExample) |
| BR (1) | BR112015016817B1 (enExample) |
| CA (1) | CA2897348C (enExample) |
| CY (1) | CY1122822T1 (enExample) |
| DK (1) | DK2945641T3 (enExample) |
| ES (1) | ES2774729T3 (enExample) |
| GB (1) | GB201300707D0 (enExample) |
| HR (1) | HRP20200351T1 (enExample) |
| LT (1) | LT2945641T (enExample) |
| PL (1) | PL2945641T3 (enExample) |
| PT (1) | PT2945641T (enExample) |
| SI (1) | SI2945641T1 (enExample) |
| WO (1) | WO2014111344A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201300707D0 (en) * | 2013-01-15 | 2013-02-27 | Novartis Ag | Compounds and processes |
| CN108697741B (zh) * | 2016-03-04 | 2023-04-14 | 悠绿那股份有限公司 | 抗病毒剂及抗病毒用食品 |
| US11998599B2 (en) | 2016-12-30 | 2024-06-04 | Vaxcyte, Inc. | Polypeptide-antigen conjugates with non-natural amino acids |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| US12050220B2 (en) | 2018-02-05 | 2024-07-30 | University Of Miyazaki | Cell labeling agent and cell labeling kit |
| CN112236457B (zh) | 2018-06-14 | 2023-08-29 | 持田制药株式会社 | 新型交联海藻酸 |
| WO2020010016A1 (en) | 2018-07-04 | 2020-01-09 | Sutrovax, Inc. | Self-adjuvanted immunogenic conjugates |
| JP2023538365A (ja) | 2020-08-19 | 2023-09-07 | バックスサイト・インコーポレイテッド | 担体－タンパク質多糖結合方法 |
| PH12023553205A1 (en) * | 2021-05-28 | 2024-02-19 | Pfizer | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| JP2024075506A (ja) * | 2022-11-22 | 2024-06-03 | ファイザー・インク | コンジュゲートさせた莢膜糖抗原を含む免疫原性組成物およびその使用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0308768A (pt) * | 2002-03-26 | 2005-02-15 | Chiron Srl | Sacarìdeos modificados possuindo estabilidade melhorada em água |
| MX2007005202A (es) * | 2004-11-01 | 2007-07-09 | Brigham & Womens Hospital | Polisacaridos de estreptococo modificados y usos de los mismos. |
| GB0502095D0 (en) * | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
| US8133515B2 (en) * | 2007-11-21 | 2012-03-13 | University Of Georgia Research Foundation, Inc. | Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds |
| ITVI20090234A1 (it) * | 2009-09-25 | 2011-03-26 | Termotecniche Fraccaro S R L Off | Dispositivo per il riscaldamento di ambienti ad alta efficienza energetica, nonche' sistema riscaldante comprendente tale dispositivo |
| EP2515914A4 (en) * | 2009-12-23 | 2013-09-11 | Scripps Research Inst | BIOCONJUGATION OF TYROSINE BY EYE REACTIONS IN AQUEOUS MEDIA |
| PL2563753T6 (pl) | 2010-04-27 | 2016-05-31 | Synaffix Bv | Stopione związki cyklooktynu i ich zastosowanie w reakcjach typu "click" bez udziału metalu |
| WO2012017701A1 (ja) * | 2010-08-05 | 2012-02-09 | 株式会社ミュージックゲート | いびき防止マスク |
| GB201101665D0 (en) | 2011-01-31 | 2011-03-16 | Novartis Ag | Immunogenic compositions |
| CN103347862B (zh) | 2010-09-27 | 2018-07-20 | 乔治亚大学研究基金公司 | 包含潜在的1,3-偶极-官能化合物的方法和由此制备的材料 |
| US20120208722A1 (en) * | 2010-10-19 | 2012-08-16 | Richard Dluhy | Surface enhanced raman spectroscopy platforms and methods |
| DK2721045T3 (en) * | 2011-06-20 | 2017-07-24 | Radiomedix Inc | COMPOSITIONS, METHODS OF SYNTHESIS AND USE OF CARBOHYDRATE TARGETED AGENTS |
| BR112014013250A2 (pt) * | 2011-12-01 | 2019-09-24 | Angiochem Inc | compostos com enzima alvo e usos dos mesmos |
| GB201300707D0 (en) * | 2013-01-15 | 2013-02-27 | Novartis Ag | Compounds and processes |
-
2013
- 2013-01-15 GB GBGB1300707.5A patent/GB201300707D0/en not_active Ceased
-
2014
- 2014-01-13 EP EP14700602.7A patent/EP2945641B1/en active Active
- 2014-01-13 JP JP2015552077A patent/JP6719209B2/ja active Active
- 2014-01-13 HR HRP20200351TT patent/HRP20200351T1/hr unknown
- 2014-01-13 BR BR112015016817-5A patent/BR112015016817B1/pt active IP Right Grant
- 2014-01-13 ES ES14700602T patent/ES2774729T3/es active Active
- 2014-01-13 CA CA2897348A patent/CA2897348C/en active Active
- 2014-01-13 DK DK14700602.7T patent/DK2945641T3/da active
- 2014-01-13 LT LTEP14700602.7T patent/LT2945641T/lt unknown
- 2014-01-13 WO PCT/EP2014/050483 patent/WO2014111344A1/en not_active Ceased
- 2014-01-13 CN CN201480012960.8A patent/CN105377282B/zh active Active
- 2014-01-13 PT PT147006027T patent/PT2945641T/pt unknown
- 2014-01-13 PL PL14700602T patent/PL2945641T3/pl unknown
- 2014-01-13 SI SI201431496T patent/SI2945641T1/sl unknown
- 2014-01-13 US US14/760,916 patent/US11135300B2/en active Active
-
2018
- 2018-12-28 JP JP2018246761A patent/JP2019073528A/ja not_active Withdrawn
-
2020
- 2020-03-13 CY CY20201100223T patent/CY1122822T1/el unknown
- 2020-03-23 JP JP2020050828A patent/JP7036854B2/ja active Active
-
2021
- 2021-05-14 US US17/320,482 patent/US12409231B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK2945641T3 (da) | 2020-03-09 |
| CN105377282A (zh) | 2016-03-02 |
| JP2019073528A (ja) | 2019-05-16 |
| GB201300707D0 (en) | 2013-02-27 |
| JP2016506905A (ja) | 2016-03-07 |
| JP6719209B2 (ja) | 2020-07-08 |
| PL2945641T3 (pl) | 2020-06-15 |
| EP2945641B1 (en) | 2020-01-01 |
| BR112015016817B1 (pt) | 2020-11-10 |
| LT2945641T (lt) | 2020-02-25 |
| EP2945641A1 (en) | 2015-11-25 |
| CA2897348A1 (en) | 2014-07-24 |
| JP2020114839A (ja) | 2020-07-30 |
| BR112015016817A8 (pt) | 2019-10-29 |
| US20160166704A1 (en) | 2016-06-16 |
| JP7036854B2 (ja) | 2022-03-15 |
| SI2945641T1 (sl) | 2020-03-31 |
| CY1122822T1 (el) | 2021-05-05 |
| ES2774729T3 (es) | 2020-07-22 |
| US20210268116A1 (en) | 2021-09-02 |
| BR112015016817A2 (pt) | 2017-07-11 |
| US11135300B2 (en) | 2021-10-05 |
| PT2945641T (pt) | 2020-03-26 |
| US12409231B2 (en) | 2025-09-09 |
| CN105377282B (zh) | 2020-07-17 |
| WO2014111344A1 (en) | 2014-07-24 |
| CA2897348C (en) | 2022-09-27 |
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