HRP20190073T1 - Novi dekstran sulfat - Google Patents

Novi dekstran sulfat

Info

Publication number
HRP20190073T1
HRP20190073T1 HRP20190073TT HRP20190073T HRP20190073T1 HR P20190073 T1 HRP20190073 T1 HR P20190073T1 HR P20190073T T HRP20190073T T HR P20190073TT HR P20190073 T HRP20190073 T HR P20190073T HR P20190073 T1 HRP20190073 T1 HR P20190073T1
Authority
HR
Croatia
Prior art keywords
dextran sulfate
new dextran
new
sulfate
dextran
Prior art date
Application number
HRP20190073TT
Other languages
English (en)
Inventor
Lars Bruce
Ulf BRASEN
Original Assignee
Tx Medic Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tx Medic Ab filed Critical Tx Medic Ab
Publication of HRP20190073T1 publication Critical patent/HRP20190073T1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/721Dextrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/02Dextran; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00Applications
    • C08L2203/02Applications for biomedical use

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HRP20190073TT 2014-11-11 2019-01-11 Novi dekstran sulfat HRP20190073T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1451349A SE538503C2 (en) 2014-11-11 2014-11-11 New dextran sulfate
EP15858497.9A EP3217988B1 (en) 2014-11-11 2015-11-10 New dextran sulfate
PCT/SE2015/051188 WO2016076780A1 (en) 2014-11-11 2015-11-10 New dextran sulfate

Publications (1)

Publication Number Publication Date
HRP20190073T1 true HRP20190073T1 (hr) 2019-03-08

Family

ID=55954726

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20190073TT HRP20190073T1 (hr) 2014-11-11 2019-01-11 Novi dekstran sulfat

Country Status (29)

Country Link
US (2) US10407514B2 (hr)
EP (1) EP3217988B1 (hr)
JP (1) JP6251459B1 (hr)
KR (1) KR101834710B1 (hr)
CN (1) CN107106595B (hr)
AU (1) AU2015347361B2 (hr)
BR (1) BR112017009752B1 (hr)
CA (1) CA2967264C (hr)
CY (1) CY1121336T1 (hr)
DK (1) DK3217988T3 (hr)
EA (1) EA032383B1 (hr)
ES (1) ES2706287T3 (hr)
HR (1) HRP20190073T1 (hr)
HU (1) HUE042806T2 (hr)
IL (1) IL251871A (hr)
LT (1) LT3217988T (hr)
MX (1) MX364314B (hr)
MY (1) MY181598A (hr)
NZ (1) NZ731141A (hr)
PH (1) PH12017500799B1 (hr)
PL (1) PL3217988T3 (hr)
PT (1) PT3217988T (hr)
RS (1) RS58222B1 (hr)
SA (1) SA517381478B1 (hr)
SE (1) SE538503C2 (hr)
SG (1) SG11201703198PA (hr)
SI (1) SI3217988T1 (hr)
TR (1) TR201900334T4 (hr)
WO (1) WO2016076780A1 (hr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018212708A1 (en) 2017-05-17 2018-11-22 Tx Medic Ab Treatment of glaucoma
PT3532072T (pt) * 2017-05-17 2020-03-05 Tx Medic Ab Tratamento do glaucoma
EP3678675A4 (en) * 2017-09-08 2021-07-07 TX Medic AB NEW USE OF DEXTRAN SULFATE
CN113286827A (zh) * 2018-06-20 2021-08-20 营养与生物科学美国第四公司 多糖衍生物和包含其的组合物
SE543275C2 (en) * 2019-03-07 2020-11-10 Tx Medic Ab Treatment efficiency evaluation
SE544015C2 (en) * 2019-06-18 2021-11-02 Tx Medic Ab Allogenic car-t cell therapy
GB202008919D0 (en) 2020-06-11 2020-07-29 Univ Birmingham Polysaccharide conpositions and therapeutic gels
SE544447C2 (en) * 2020-09-29 2022-05-31 Tx Medic Ab Treatment of fatty liver diseases
CN116322709A (zh) * 2020-10-09 2023-06-23 Tx医生公司 使用硫酸葡聚糖的肌肉萎缩的治疗
WO2022220736A1 (en) * 2021-04-14 2022-10-20 Tx Medic Ab Treatment of virus infections

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3141014A (en) * 1960-03-31 1964-07-14 Meito Sangyo Kk Sodium and potassium salts of the dextran sulphuric acid ester having substantially no anticoagulant activity but having lipolytic activity and the method of preparation thereof
JPS4730167Y1 (hr) 1967-03-09 1972-09-09
JPS469570Y1 (hr) 1968-08-28 1971-04-05
US4232150A (en) 1979-07-09 1980-11-04 American Cyanamid Company Oligosaccharide precursors to substituted O-α-D and O-β-D-multigalactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6α-D-glucopyranoses
US4221907A (en) 1979-07-09 1980-09-09 American Cyanamid Company Substituted O-α-D and O-β-D-multi-galactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6 α-D-glucopyranoses
US4855416A (en) * 1983-07-25 1989-08-08 Polydex Pharmaceuticals, Ltd Method for the manufacture of dextran sulfate and salts thereof
EP0240098A3 (en) 1986-04-04 1989-05-10 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Oligo and polysaccharides for the treatment of diseases caused by retroviruses
IL79254A0 (en) 1986-06-26 1986-09-30 Hadassah Med Org Compositions for preventing graft rejection
IL88554A0 (en) 1988-12-01 1989-07-31 Hadassah Med Org Compositions containing a compound binding to a heparin receptor
TW318142B (hr) 1991-06-03 1997-10-21 Mitsubishi Chemicals Co Ltd
US5464815A (en) 1993-09-08 1995-11-07 Genentech, Inc. Inhibition of heparin-binding
JPH08301771A (ja) 1995-03-08 1996-11-19 Shiseido Co Ltd 腎疾患の予防または治療用製剤
AUPN261895A0 (en) * 1995-04-28 1995-05-18 Australian National University, The Preparation and use of sulfated oligosaccharides
FR2772382B1 (fr) 1997-12-11 2000-03-03 Solutions Derives de dextrane, leur procede de preparation et leurs applications comme medicaments a action biologique specifique
JP2000178196A (ja) 1998-12-11 2000-06-27 Seikagaku Kogyo Co Ltd 新規ヒアルロニダーゼ阻害剤及び外用剤
CN1347919A (zh) 2000-10-12 2002-05-08 中国科学院生态环境研究中心 带有支链的硫酸酯化寡糖的制备
FR2832708B1 (fr) 2001-11-29 2004-02-13 Organes Tissus Regeneration Re Procede de sulfonation de composes comprenant des groupements hydroxyle (oh) libres ou des amines primaires ou secondaires
US20040009953A1 (en) * 2002-01-10 2004-01-15 Comper Wayne D. Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof
SE525461C3 (sv) 2002-11-28 2005-03-23 Prophymed Ab Ny användning av dextransulfat
US20110008343A1 (en) 2007-06-08 2011-01-13 Lambris John D Method Of Reducing Tissue Loss In Pancreatic Islet Cell Transplantation
MX2011008119A (es) 2009-02-02 2011-08-24 Otsuka Chemical Co Ltd Derivado de acido hialuronico polisulfatado de bajo peso molecular, y medicamento que contiene el mismo.
SE537742C2 (sv) 2013-05-13 2015-10-13 Tx Medic Ab Dextransulfat för cellmobilisering
CN103554297B (zh) * 2013-10-21 2016-09-07 兰州大学 一种高硫代度红芪多糖硫酸酯的制备方法及其应用
MY178989A (en) * 2014-06-12 2020-10-26 Tx Medic Ab The use of dextran sulfate having an average molecular weight below 10000 da for inducing angiogenisis in a subject

Also Published As

Publication number Publication date
HUE042806T2 (hu) 2019-07-29
NZ731141A (en) 2019-07-26
LT3217988T (lt) 2019-02-11
RS58222B1 (sr) 2019-03-29
SA517381478B1 (ar) 2020-09-28
EP3217988A4 (en) 2018-05-30
PT3217988T (pt) 2019-01-29
EA032383B1 (ru) 2019-05-31
AU2015347361B2 (en) 2019-01-17
PH12017500799A1 (en) 2017-10-02
SE1451349A1 (en) 2016-05-12
CA2967264A1 (en) 2016-05-19
SE538503C2 (en) 2016-08-16
WO2016076780A1 (en) 2016-05-19
SI3217988T1 (sl) 2019-02-28
MY181598A (en) 2020-12-29
JP2018501332A (ja) 2018-01-18
US10730960B2 (en) 2020-08-04
ES2706287T3 (es) 2019-03-28
EA201790856A1 (ru) 2017-09-29
US20180298116A1 (en) 2018-10-18
CA2967264C (en) 2018-02-20
SG11201703198PA (en) 2017-05-30
BR112017009752A2 (pt) 2018-02-20
BR112017009752B1 (pt) 2022-12-06
US10407514B2 (en) 2019-09-10
KR20170059008A (ko) 2017-05-29
PL3217988T3 (pl) 2019-05-31
MX2017006122A (es) 2017-08-10
IL251871A (en) 2017-11-30
CY1121336T1 (el) 2020-05-29
CN107106595A (zh) 2017-08-29
JP6251459B1 (ja) 2017-12-20
EP3217988A1 (en) 2017-09-20
MX364314B (es) 2019-04-22
CN107106595B (zh) 2018-10-30
DK3217988T3 (en) 2019-02-04
PH12017500799B1 (en) 2017-10-02
KR101834710B1 (ko) 2018-03-05
TR201900334T4 (tr) 2019-02-21
US20190375859A1 (en) 2019-12-12
AU2015347361A1 (en) 2017-05-11
EP3217988B1 (en) 2018-10-24

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