HRP20182088T1 - Režim doziranja za inhibitore janus kinaze (jak) - Google Patents
Režim doziranja za inhibitore janus kinaze (jak)Info
- Publication number
- HRP20182088T1 HRP20182088T1 HRP20182088TT HRP20182088T HRP20182088T1 HR P20182088 T1 HRP20182088 T1 HR P20182088T1 HR P20182088T T HRP20182088T T HR P20182088TT HR P20182088 T HRP20182088 T HR P20182088T HR P20182088 T1 HRP20182088 T1 HR P20182088T1
- Authority
- HR
- Croatia
- Prior art keywords
- strong
- kinase inhibitors
- janus kinase
- dosage regime
- regime
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261674289P | 2012-07-20 | 2012-07-20 | |
| US201361815803P | 2013-04-25 | 2013-04-25 | |
| PCT/US2013/051015 WO2014015107A1 (en) | 2012-07-20 | 2013-07-18 | Dosing regimen for janus kinase (jak) inhibitors |
| EP13742573.2A EP2874630B1 (en) | 2012-07-20 | 2013-07-18 | Dosing regimen for janus kinase (jak) inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20182088T1 true HRP20182088T1 (hr) | 2019-02-08 |
Family
ID=48901189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20182088TT HRP20182088T1 (hr) | 2012-07-20 | 2013-07-18 | Režim doziranja za inhibitore janus kinaze (jak) |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9522151B2 (enExample) |
| EP (1) | EP2874630B1 (enExample) |
| JP (2) | JP6022063B2 (enExample) |
| KR (2) | KR20150028299A (enExample) |
| CN (2) | CN104470525A (enExample) |
| AU (1) | AU2013292547B2 (enExample) |
| BR (1) | BR112015000808A2 (enExample) |
| CA (1) | CA2878867C (enExample) |
| CY (1) | CY1121436T1 (enExample) |
| DK (1) | DK2874630T3 (enExample) |
| ES (1) | ES2707627T3 (enExample) |
| HK (2) | HK1209314A1 (enExample) |
| HR (1) | HRP20182088T1 (enExample) |
| HU (1) | HUE042771T2 (enExample) |
| IN (1) | IN2015DN00370A (enExample) |
| LT (1) | LT2874630T (enExample) |
| MX (1) | MX360857B (enExample) |
| NZ (1) | NZ703152A (enExample) |
| PL (1) | PL2874630T3 (enExample) |
| PT (1) | PT2874630T (enExample) |
| RS (1) | RS58242B1 (enExample) |
| SI (1) | SI2874630T1 (enExample) |
| SM (1) | SMT201900044T1 (enExample) |
| WO (1) | WO2014015107A1 (enExample) |
| ZA (1) | ZA201500134B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3290421B1 (en) | 2013-02-22 | 2019-01-02 | Pfizer Inc | Combination of pyrrolo [2, 3 -d]pyrimidine derivatives with one or more additional agents as inhibitors of janus- related kinases (jak) |
| JP6585158B2 (ja) | 2014-08-12 | 2019-10-02 | ファイザー・インク | ヤヌスキナーゼの阻害に有用なピロロ［２，３−ｄ］ピリミジン誘導体 |
| US11365198B2 (en) | 2015-10-16 | 2022-06-21 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
| US11780848B2 (en) | 2015-10-16 | 2023-10-10 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1- carboxamide and solid state forms thereof |
| US10550126B2 (en) | 2015-10-16 | 2020-02-04 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
| US12365689B2 (en) | 2015-10-16 | 2025-07-22 | Abbvie Inc. | Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof |
| CA3251507A1 (en) | 2015-10-16 | 2025-05-21 | Abbvie Inc | Use of a solid dosage form comprising (3s,4r)-3-ethyl-4-(3h-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide for treating rheumatoid arthritis |
| WO2017143014A1 (en) * | 2016-02-16 | 2017-08-24 | Brian Kim | Jak inhibitors and uses thereof |
| CN107098908B (zh) * | 2016-02-23 | 2021-01-08 | 欣凯医药科技(上海)有限公司 | 一种吡咯并嘧啶类化合物的制备方法和应用 |
| KR102195348B1 (ko) | 2018-11-15 | 2020-12-24 | 에이치케이이노엔 주식회사 | 단백질 키나제 억제제로서의 신규 화합물 및 이를 포함하는 약제학적 조성물 |
| CN111499641B (zh) * | 2019-01-30 | 2021-06-04 | 格格巫（珠海）生物科技有限公司 | 一种jak抑制剂及其制备方法 |
| US11992490B2 (en) | 2019-10-16 | 2024-05-28 | Incyte Corporation | Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP) |
| EP4263559A1 (en) | 2020-12-18 | 2023-10-25 | Boehringer Ingelheim Animal Health USA Inc. | Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof |
| MX2023010835A (es) * | 2021-03-16 | 2023-09-29 | Hk Inno N Corp | Nuevas sales de compuestos heterocíclicos como inhibidores de proteínas quinasas y sus usos. |
| CA3216017A1 (en) * | 2021-04-22 | 2022-10-27 | Shengjian Huang | Pharmaceutical composition containing jak3/jak1/tbk1 selective inhibitor and medical use thereof |
| WO2024259429A2 (en) * | 2023-06-16 | 2024-12-19 | The University Of Chicago | Methods and compositions for pharmaceutically relevant interactions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS50087B (sr) * | 1998-06-19 | 2009-01-22 | Pfizer Products Inc., | Pirolo (2,3-d) pirimidin jedinjenja |
| PT2384326E (pt) * | 2008-08-20 | 2014-06-09 | Zoetis Llc | Compostos de pirrolo[2,3-d]pirimidina |
-
2013
- 2013-07-18 KR KR1020157001085A patent/KR20150028299A/ko not_active Ceased
- 2013-07-18 LT LTEP13742573.2T patent/LT2874630T/lt unknown
- 2013-07-18 PT PT13742573T patent/PT2874630T/pt unknown
- 2013-07-18 SI SI201331328T patent/SI2874630T1/sl unknown
- 2013-07-18 HU HUE13742573A patent/HUE042771T2/hu unknown
- 2013-07-18 IN IN370DEN2015 patent/IN2015DN00370A/en unknown
- 2013-07-18 HK HK15109423.1A patent/HK1209314A1/xx unknown
- 2013-07-18 ES ES13742573T patent/ES2707627T3/es active Active
- 2013-07-18 EP EP13742573.2A patent/EP2874630B1/en not_active Revoked
- 2013-07-18 CA CA2878867A patent/CA2878867C/en active Active
- 2013-07-18 MX MX2015000871A patent/MX360857B/es active IP Right Grant
- 2013-07-18 WO PCT/US2013/051015 patent/WO2014015107A1/en not_active Ceased
- 2013-07-18 PL PL13742573T patent/PL2874630T3/pl unknown
- 2013-07-18 JP JP2015523243A patent/JP6022063B2/ja active Active
- 2013-07-18 HR HRP20182088TT patent/HRP20182088T1/hr unknown
- 2013-07-18 US US14/415,047 patent/US9522151B2/en active Active
- 2013-07-18 CN CN201380038563.3A patent/CN104470525A/zh active Pending
- 2013-07-18 AU AU2013292547A patent/AU2013292547B2/en active Active
- 2013-07-18 NZ NZ703152A patent/NZ703152A/en unknown
- 2013-07-18 CN CN201810369706.3A patent/CN108354938A/zh active Pending
- 2013-07-18 KR KR1020177007913A patent/KR20170034949A/ko not_active Ceased
- 2013-07-18 BR BR112015000808A patent/BR112015000808A2/pt not_active Application Discontinuation
- 2013-07-18 SM SM20190044T patent/SMT201900044T1/it unknown
- 2013-07-18 RS RS20190051A patent/RS58242B1/sr unknown
- 2013-07-18 DK DK13742573.2T patent/DK2874630T3/en active
-
2015
- 2015-01-08 ZA ZA2015/00134A patent/ZA201500134B/en unknown
-
2016
- 2016-08-05 JP JP2016154135A patent/JP2017019816A/ja active Pending
-
2018
- 2018-08-23 HK HK18110906.2A patent/HK1252083A1/zh unknown
-
2019
- 2019-02-14 CY CY20191100203T patent/CY1121436T1/el unknown
Also Published As
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