HRP20181918T1 - Postupak za sintezu derivata benzazepina - Google Patents

Postupak za sintezu derivata benzazepina

Info

Publication number
HRP20181918T1
HRP20181918T1 HRP20181918TT HRP20181918T HRP20181918T1 HR P20181918 T1 HRP20181918 T1 HR P20181918T1 HR P20181918T T HRP20181918T T HR P20181918TT HR P20181918 T HRP20181918 T HR P20181918T HR P20181918 T1 HRP20181918 T1 HR P20181918T1
Authority
HR
Croatia
Prior art keywords
synthesis
benzazepine derivatives
benzazepine
derivatives
Prior art date
Application number
HRP20181918TT
Other languages
English (en)
Inventor
Sándor GARADNAY
József NEU
Tamás SZABÓ
Original Assignee
Richter Gedeon Nyrt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt. filed Critical Richter Gedeon Nyrt.
Publication of HRP20181918T1 publication Critical patent/HRP20181918T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Epoxy Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HRP20181918TT 2014-11-19 2018-11-19 Postupak za sintezu derivata benzazepina HRP20181918T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU1400545A HU230826B1 (hu) 2014-11-19 2014-11-19 Eljárás benzazepin származékok előállítására
PCT/IB2015/058913 WO2016079684A1 (en) 2014-11-19 2015-11-18 Process for the synthesis of benzazepine derivatives
EP15804597.1A EP3221297B1 (en) 2014-11-19 2015-11-18 Process for the synthesis of benzazepine derivatives

Publications (1)

Publication Number Publication Date
HRP20181918T1 true HRP20181918T1 (hr) 2019-01-11

Family

ID=89991647

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20181918TT HRP20181918T1 (hr) 2014-11-19 2018-11-19 Postupak za sintezu derivata benzazepina

Country Status (10)

Country Link
EP (1) EP3221297B1 (hr)
EA (1) EA032259B1 (hr)
ES (1) ES2697341T3 (hr)
GE (1) GEP20207064B (hr)
HR (1) HRP20181918T1 (hr)
HU (2) HU230826B1 (hr)
PL (1) PL3221297T3 (hr)
SI (1) SI3221297T1 (hr)
UA (1) UA122133C2 (hr)
WO (1) WO2016079684A1 (hr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3101010A1 (en) 2015-06-03 2016-12-07 Urquima S.A. New method for the preparation of highly pure ivabradine base and salts thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265890A (en) 1978-07-07 1981-05-05 Smithkline Corporation 6-Phenyl thio- and 6-cyclohexyl thio-2,3,4,5-tetrahydro-1H-3-benzazepines
DE3119874A1 (de) * 1981-05-19 1982-12-09 Dr. Karl Thomae Gmbh, 7950 Biberach "benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel"
DE3418270A1 (de) 1984-05-17 1985-11-21 Dr. Karl Thomae Gmbh, 7950 Biberach Neue aminotetralinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
ZA882080B (en) 1987-03-27 1989-04-26 Schering Corp Substituted benzazepines,their preparation and pharmaceutical compositions containing them
FR2681862B1 (fr) 1991-09-27 1993-11-12 Adir Cie Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
FR2702477B1 (fr) 1993-03-08 1995-04-28 Synthelabo Dérivés de benzoxazine, leur préparation et leur application en thérapeutique.
FR2932800B1 (fr) * 2008-06-20 2015-02-20 Servier Lab Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
CN102264689B (zh) 2008-12-22 2014-12-31 新梅斯托克尔卡公司 制备伊伐布雷定的方法

Also Published As

Publication number Publication date
EP3221297B1 (en) 2018-08-22
EP3221297A1 (en) 2017-09-27
WO2016079684A1 (en) 2016-05-26
GEAP201914518A (hr) 2019-09-25
HU230826B1 (hu) 2018-07-30
GEP20207064B (en) 2020-02-10
ES2697341T3 (es) 2019-01-23
EA032259B1 (ru) 2019-04-30
PL3221297T3 (pl) 2019-02-28
SI3221297T1 (sl) 2018-12-31
UA122133C2 (uk) 2020-09-25
EA201791098A1 (ru) 2017-09-29
HUP1400545A2 (hu) 2016-05-30
HUE040001T2 (hu) 2019-02-28

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