HUP1400518A2 - Eljárás tofacitinib elõállítására - Google Patents

Eljárás tofacitinib elõállítására

Info

Publication number
HUP1400518A2
HUP1400518A2 HU1400518A HUP1400518A HUP1400518A2 HU P1400518 A2 HUP1400518 A2 HU P1400518A2 HU 1400518 A HU1400518 A HU 1400518A HU P1400518 A HUP1400518 A HU P1400518A HU P1400518 A2 HUP1400518 A2 HU P1400518A2
Authority
HU
Hungary
Prior art keywords
tofacitinib
preparation
Prior art date
Application number
HU1400518A
Other languages
English (en)
Inventor
Marta Porcs-Makkay
Enikoe Molnar
Gyula Simig
Angela Pandur
Gabor Nemeth
Balazs Volk
Mezei Erzsebet Terebesine
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU1400518A priority Critical patent/HU231015B1/hu
Publication of HUP1400518A2 publication Critical patent/HUP1400518A2/hu
Publication of HU231015B1 publication Critical patent/HU231015B1/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
HU1400518A 2014-11-03 2014-11-03 Eljárás tofacitinib előállítására HU231015B1 (hu)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU1400518A HU231015B1 (hu) 2014-11-03 2014-11-03 Eljárás tofacitinib előállítására

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU1400518A HU231015B1 (hu) 2014-11-03 2014-11-03 Eljárás tofacitinib előállítására

Publications (2)

Publication Number Publication Date
HUP1400518A2 true HUP1400518A2 (hu) 2016-05-30
HU231015B1 HU231015B1 (hu) 2019-11-28

Family

ID=89991633

Family Applications (1)

Application Number Title Priority Date Filing Date
HU1400518A HU231015B1 (hu) 2014-11-03 2014-11-03 Eljárás tofacitinib előállítására

Country Status (1)

Country Link
HU (1) HU231015B1 (hu)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108689915A (zh) * 2018-07-25 2018-10-23 甘肃皓天医药科技有限责任公司 一种用于制备托法替尼的中间体的合成方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108689915A (zh) * 2018-07-25 2018-10-23 甘肃皓天医药科技有限责任公司 一种用于制备托法替尼的中间体的合成方法

Also Published As

Publication number Publication date
HU231015B1 (hu) 2019-11-28

Similar Documents

Publication Publication Date Title
IL251560A0 (en) Methods for preparing ribosides
IL247515A0 (en) Snekribirock for the treatment of leprosy
ZA201706795B (en) Process for the preparation of dicycloplatin
EP3166931A4 (en) An improved process for the preparation of enzalutamide
ZA201700254B (en) Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids
IL248267A0 (en) A process for preparing converted cycloserines
EP3230280A4 (en) Process for preparation of luliconazole
PT3122349T (pt) Composições para o tratamento da autodigestão
SG11201702700UA (en) Methods for the treatment of peri-implantitis
IL251946A0 (en) Process for making micro particles
IL247443B (en) Process for the preparation of 5-fluorotryptophol
ZA201701973B (en) Process for the preparation of halo-substituted trifluoroacetophenones
HUE061732T2 (hu) Eljárás részecskék elõállítására
HUP1400378A2 (hu) Eljárás apixaban elõállítására
HUP1400518A2 (hu) Eljárás tofacitinib elõállítására
IL241974A0 (en) Process for making erlotinib
HUE039419T2 (hu) Eljárás ramipril elõállítására
HUE043114T2 (hu) Eljárás tetrakonazol elõállítására
GB201505667D0 (en) Process for the preparation of butadiene
HUP1500034A1 (en) Process for the preparation of vortioxetine salts