HRP20151384T1 - Postupak utvrđivanja specifičnog kemijskog otiska u proizvodnji mikotoksina - Google Patents
Postupak utvrđivanja specifičnog kemijskog otiska u proizvodnji mikotoksina Download PDFInfo
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- HRP20151384T1 HRP20151384T1 HRP20151384TT HRP20151384T HRP20151384T1 HR P20151384 T1 HRP20151384 T1 HR P20151384T1 HR P20151384T T HRP20151384T T HR P20151384TT HR P20151384 T HRP20151384 T HR P20151384T HR P20151384 T1 HRP20151384 T1 HR P20151384T1
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- 238000000034 method Methods 0.000 title claims 10
- 239000000126 substance Substances 0.000 title claims 7
- 231100000678 Mycotoxin Toxicity 0.000 title claims 5
- 239000002636 mycotoxin Substances 0.000 title claims 5
- 239000012855 volatile organic compound Substances 0.000 claims 13
- 241000233866 Fungi Species 0.000 claims 6
- KMXFZRSJMDYPPG-UHFFFAOYSA-N tetratetracontane Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC KMXFZRSJMDYPPG-UHFFFAOYSA-N 0.000 claims 6
- VLXDPFLIRFYIME-QRTUWBSPSA-N alpha-ylangene Natural products C1C=C(C)[C@@H]2[C@@]3(C)CC[C@@H](C(C)C)[C@@H]2[C@H]31 VLXDPFLIRFYIME-QRTUWBSPSA-N 0.000 claims 5
- 229930004725 sesquiterpene Natural products 0.000 claims 4
- 150000004354 sesquiterpene derivatives Chemical class 0.000 claims 4
- KOZDEDRKEDUXDC-UHFFFAOYSA-N 2,3-dimethylbutan-2-ylbenzene Chemical compound CC(C)C(C)(C)C1=CC=CC=C1 KOZDEDRKEDUXDC-UHFFFAOYSA-N 0.000 claims 3
- OOVOQEZEKOHUDM-UHFFFAOYSA-N 2-butoxy-6-methylphenol Chemical compound CCCCOC1=CC=CC(C)=C1O OOVOQEZEKOHUDM-UHFFFAOYSA-N 0.000 claims 3
- PIUUDKDOAUICQP-UHFFFAOYSA-N 2-methylpentan-2-ylbenzene Chemical compound CCCC(C)(C)C1=CC=CC=C1 PIUUDKDOAUICQP-UHFFFAOYSA-N 0.000 claims 3
- NPAWGLOPXKCTCV-UHFFFAOYSA-N 5-phenyldodecane Chemical compound CCCCCCCC(CCCC)C1=CC=CC=C1 NPAWGLOPXKCTCV-UHFFFAOYSA-N 0.000 claims 3
- PGVOXXHNGYYHHB-UHFFFAOYSA-N dodecan-3-ylbenzene Chemical compound CCCCCCCCCC(CC)C1=CC=CC=C1 PGVOXXHNGYYHHB-UHFFFAOYSA-N 0.000 claims 3
- RHDHXBLZBVAPTL-UHFFFAOYSA-N dodecan-4-ylbenzene Chemical compound CCCCCCCCC(CCC)C1=CC=CC=C1 RHDHXBLZBVAPTL-UHFFFAOYSA-N 0.000 claims 3
- 230000002538 fungal effect Effects 0.000 claims 3
- 229930001612 germacrene Natural products 0.000 claims 3
- YDLBHMSVYMFOMI-SDFJSLCBSA-N germacrene Chemical compound CC(C)[C@H]1CC\C(C)=C\CC\C(C)=C\C1 YDLBHMSVYMFOMI-SDFJSLCBSA-N 0.000 claims 3
- DGROBZZOOZUCTC-UHFFFAOYSA-N icosan-7-ylbenzene Chemical compound CCCCCCCCCCCCCC(CCCCCC)C1=CC=CC=C1 DGROBZZOOZUCTC-UHFFFAOYSA-N 0.000 claims 3
- LFYXNXGVLGKVCJ-FBIMIBRVSA-N 2-methylisoborneol Chemical compound C1C[C@@]2(C)[C@](C)(O)C[C@@H]1C2(C)C LFYXNXGVLGKVCJ-FBIMIBRVSA-N 0.000 claims 2
- LFYXNXGVLGKVCJ-UHFFFAOYSA-N 2-methylisoborneol Natural products C1CC2(C)C(C)(O)CC1C2(C)C LFYXNXGVLGKVCJ-UHFFFAOYSA-N 0.000 claims 2
- VLXDPFLIRFYIME-GZBLMMOJSA-N Copaene Natural products C1C=C(C)[C@H]2[C@]3(C)CC[C@H](C(C)C)[C@H]2[C@@H]31 VLXDPFLIRFYIME-GZBLMMOJSA-N 0.000 claims 2
- VLXDPFLIRFYIME-BTFPBAQTSA-N copaene Chemical compound C1C=C(C)[C@H]2[C@]3(C)CC[C@@H](C(C)C)[C@H]2[C@@H]31 VLXDPFLIRFYIME-BTFPBAQTSA-N 0.000 claims 2
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims 2
- 230000004060 metabolic process Effects 0.000 claims 2
- 241000894007 species Species 0.000 claims 2
- FZZNNPQZDRVKLU-IPOFZDNWSA-N (4r,4ar,8as)-1,6-dimethyl-4-propan-2-yl-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene Chemical compound C1CC(C)C[C@@H]2[C@@H](C(C)C)CCC(C)[C@@H]21 FZZNNPQZDRVKLU-IPOFZDNWSA-N 0.000 claims 1
- 238000011109 contamination Methods 0.000 claims 1
- -1 muurolan Chemical compound 0.000 claims 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0004—Gaseous mixtures, e.g. polluted air
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Diabetes (AREA)
- Combustion & Propulsion (AREA)
- Nanotechnology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Claims (8)
1. Postupak utvrđivanja proizvodnje mikotoksina u unutarnjem okolišu koji obuhvaća korake:
a) uzimanje uzorka zraka iz unutarnjeg okoliša, i zatim
b) utvrđivanje volatilnih organskih spojeva (engl. volatile organic compounds, VOC) u uzorku,
naznačen time što korak b) obuhvaća traženje kemijskog otiska koji se sastoji od barem jedne ciljne molekule koja je VOC povezan s proizvodnjom mikotoksina i koja se izabire iz grupe koju čine ylangen, D germakren, 1,1-dimetilbutilbenzen, 1,1,2-trimetil-propil-benzen, 1-heksiltetradecilbenzen, tetratetrakontan, 1-etildecilbenzen, hidroksitoluen butilat, 1-butiloktilbenzen i 1-propilnonilbenzen.
2. Postupak prema zahtjevu 1, naznačen time što ta ciljna molekula obuhvaća barem dvije ciljne molekule koje se izabiru iz grupe koju čine kububen, kadien, kopaen, ilangen, D germakren, muurolan, 1,1-dimetilbutilbenzen, 1,1,2-trimetil-propil-benzen, 1-heksiltetradecilbenzen, tetratetrakontan, 1-etildecilbenzen, hidroksitoluen butilat, 1-butiloktilbenzen, 1-propilnonilbenzen, 2-metilizoborneol, barem jedan seskviterpen i od kojih je barem jedna cijna molekula seskviterpen.
3. Postupak prema bilo kojem od zahtjeva 1 ili 2, naznačen time što kemijski otisak obuhvaća sve navedene ciljne molekule.
4. Postupak prema bilo kojem od zahtjeva 1 do 3, naznačen time što obuhvaća korak traženja zona kontaminiranih gljivicama koji se provodi prije koraka (a).
5. Postupak utvrđivanja proizvodnje mikotoksina u unutarnjem okolišu prema zahtjevu 1 koji obuhvaća korake:
a) uzimanje uzorka zraka iz unutarnjeg okoliša; zatim
b) utvrđivanje VOC-ova u uzorku, koje obuhvaća utvrđivanje prisutnosti ili odsutnosti određenih poznatih VOC-ova koji nastaju u metabolizmu gljivica, gdje ti poznati VOC-ovi obuhvaćaju barem jedan VOC iz svake od sljedeće tri kategorije VOC-ova:
1) VOC-ovi koji se oslobađaju nezavisno o vrsti gljivice i mediju u kojem se nalazi, i koje oslobađaju samo gljivične vrste;
2) VOC-ovi koji se oslobađaju nezavisno o vrsti gljivice i mediju, i koje oslobađaju i biološke vrste koje nisu gljivice;
3) VOC-ovi koji se oslobađaju kao funkcija vrste gljivice i/ili medija u kojem se nalazi;
c) izračun kemijskog indeksa fungalne kontaminacije kao funkcije u vezi s prisutnosti i odsutnosti poznatih VOC-ova koji dolaze iz metabolizma gljivica,
naznačen time što postupak obuhvaća korak (d) traženja kemijskog otiska koji se sastoji od barem jedne ciljne molekule koja je VOC povezan s proizvodnjom mikotoksina.
6. Postupak prema zahtjevu 5, naznačen time što se ta ciljna molekula izabire iz grupe koju čine kububen, kadien, kopaen, ilangen, D germakren, muurolan, 1,1-dimetilbutilbenzen, 1,1,2-trimetil-propil-benzen, 1-heksiltetradecilbenzen, tetratetrakontan, 1-etildecilbenzen, hidroksitoluen butilat, 1-butiloktilbenzen, 1-propilnonilbenzen, 2-metilizoborneol i barem jedan seskviterpen.
7. Postupak prema bilo kojem od zahtjeva 5 ili 6, naznačen time što se kemijski otisak sastoji od barem dvije ciljne molekule od kojih je barem jedna seskviterpen.
8. Postupak prema bilo kojem od zahtjeva 5 do 7, naznačen time što kemijski otisak obuhvaća sve navedene ciljne molekule.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1157992A FR2979992B1 (fr) | 2011-09-08 | 2011-09-08 | Procede de determination d'une empreinte chimique specifique de la production de mycotoxines |
| EP12181259.8A EP2568283B1 (fr) | 2011-09-08 | 2012-08-21 | Procédé de détermination d'une empreinte chimique spécifique de la production de mycotoxines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20151384T1 true HRP20151384T1 (hr) | 2016-01-29 |
Family
ID=46650459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20151384TT HRP20151384T1 (hr) | 2011-09-08 | 2015-12-16 | Postupak utvrđivanja specifičnog kemijskog otiska u proizvodnji mikotoksina |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9347916B2 (hr) |
| EP (1) | EP2568283B1 (hr) |
| CA (1) | CA2788495C (hr) |
| DK (1) | DK2568283T3 (hr) |
| ES (1) | ES2557117T3 (hr) |
| FR (1) | FR2979992B1 (hr) |
| HR (1) | HRP20151384T1 (hr) |
| HU (1) | HUE028225T2 (hr) |
| PL (1) | PL2568283T3 (hr) |
| PT (1) | PT2568283E (hr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2995693B1 (fr) | 2012-09-14 | 2016-10-28 | Centre Scient Et Technique Du Batiment | Elaboration d'une empreinte de contamination aspergillaire basee sur la detection de covm |
| LT6458B (lt) | 2016-01-06 | 2017-09-25 | Gamtos Tyrimå² Centras | Grūdų užteršimo pelėsiniais grybais aptikimo būdas |
| CN109313171A (zh) * | 2016-06-22 | 2019-02-05 | 株式会社岛津制作所 | 信息处理装置、信息处理方法以及信息处理程序 |
| CN106018513A (zh) * | 2016-06-23 | 2016-10-12 | 陕西科技大学 | 一种检测乳品掺假的指纹图谱方法 |
| US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
| US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
| US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
| US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
| US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
| US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
| US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
| CN115236239B (zh) * | 2022-08-09 | 2023-12-29 | 多特瑞(上海)商贸有限公司 | 一种五味子精油中α-可巴烯含量的检测方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2913501B1 (fr) * | 2007-03-05 | 2012-02-03 | Ct Scient Et Tech Du Batiment Cstb | Procede de detection d'une contamination fongique |
-
2011
- 2011-09-08 FR FR1157992A patent/FR2979992B1/fr active Active
-
2012
- 2012-08-21 PT PT121812598T patent/PT2568283E/pt unknown
- 2012-08-21 DK DK12181259.8T patent/DK2568283T3/en active
- 2012-08-21 ES ES12181259.8T patent/ES2557117T3/es active Active
- 2012-08-21 EP EP12181259.8A patent/EP2568283B1/fr active Active
- 2012-08-21 PL PL12181259T patent/PL2568283T3/pl unknown
- 2012-08-21 HU HUE12181259A patent/HUE028225T2/en unknown
- 2012-08-30 CA CA2788495A patent/CA2788495C/fr active Active
- 2012-09-07 US US13/607,307 patent/US9347916B2/en active Active
-
2015
- 2015-12-16 HR HRP20151384TT patent/HRP20151384T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2557117T3 (es) | 2016-01-22 |
| EP2568283B1 (fr) | 2015-11-04 |
| PT2568283E (pt) | 2016-01-13 |
| CA2788495C (fr) | 2019-09-24 |
| FR2979992A1 (fr) | 2013-03-15 |
| EP2568283A1 (fr) | 2013-03-13 |
| DK2568283T3 (en) | 2016-01-11 |
| US20130244272A1 (en) | 2013-09-19 |
| PL2568283T3 (pl) | 2016-03-31 |
| HUE028225T2 (en) | 2016-12-28 |
| CA2788495A1 (fr) | 2013-03-08 |
| FR2979992B1 (fr) | 2016-05-06 |
| US9347916B2 (en) | 2016-05-24 |
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