HRP20150613T1 - Sol benzojeve kiseline otamiksabana - Google Patents
Sol benzojeve kiseline otamiksabana Download PDFInfo
- Publication number
- HRP20150613T1 HRP20150613T1 HRP20150613TT HRP20150613T HRP20150613T1 HR P20150613 T1 HRP20150613 T1 HR P20150613T1 HR P20150613T T HRP20150613T T HR P20150613TT HR P20150613 T HRP20150613 T HR P20150613T HR P20150613 T1 HRP20150613 T1 HR P20150613T1
- Authority
- HR
- Croatia
- Prior art keywords
- benzoic acid
- amino
- methyl
- acid salt
- imino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11305348 | 2011-03-29 | ||
| US201161500342P | 2011-06-23 | 2011-06-23 | |
| PCT/EP2012/055364 WO2012130821A1 (en) | 2011-03-29 | 2012-03-27 | Benzoic acid salt of otamixaban |
| EP12711858.6A EP2691371B1 (en) | 2011-03-29 | 2012-03-27 | Benzoic acid salt of otamixaban |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20150613T1 true HRP20150613T1 (hr) | 2015-07-17 |
Family
ID=44065390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20150613TT HRP20150613T1 (hr) | 2011-03-29 | 2012-03-27 | Sol benzojeve kiseline otamiksabana |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8993602B2 (enExample) |
| EP (1) | EP2691371B1 (enExample) |
| JP (1) | JP5959617B2 (enExample) |
| KR (1) | KR101852226B1 (enExample) |
| CN (1) | CN103562183B (enExample) |
| AU (1) | AU2012234325B2 (enExample) |
| BR (1) | BR112013025105A2 (enExample) |
| CA (1) | CA2830965C (enExample) |
| CY (1) | CY1116659T1 (enExample) |
| DK (1) | DK2691371T3 (enExample) |
| ES (1) | ES2539236T3 (enExample) |
| HR (1) | HRP20150613T1 (enExample) |
| IL (1) | IL228574A (enExample) |
| MX (1) | MX2013011266A (enExample) |
| MY (1) | MY161396A (enExample) |
| PL (1) | PL2691371T3 (enExample) |
| PT (1) | PT2691371E (enExample) |
| RU (1) | RU2597423C2 (enExample) |
| SG (1) | SG193612A1 (enExample) |
| SI (1) | SI2691371T1 (enExample) |
| WO (1) | WO2012130821A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5993933B2 (ja) | 2011-03-29 | 2016-09-14 | サノフイ | 安定性を改善したオタミキサバン製剤 |
| CN106565698B (zh) * | 2016-08-15 | 2019-03-08 | 南京帕隆材料科技有限公司 | 取代噻唑类衍生物及其制备方法和用途 |
| CN106518859B (zh) * | 2016-08-15 | 2019-01-18 | 南京帕隆材料科技有限公司 | 噻唑类衍生物及其制备方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5424334A (en) | 1991-12-19 | 1995-06-13 | G. D. Searle & Co. | Peptide mimetic compounds useful as platelet aggregation inhibitors |
| AU723338B2 (en) * | 1996-01-02 | 2000-08-24 | Aventis Pharmaceuticals Inc. | Substituted n-{(aminoiminomethyl or aminomethyl)phenyl}propyl amides |
| US6080767A (en) * | 1996-01-02 | 2000-06-27 | Aventis Pharmaceuticals Products Inc. | Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides |
| GB0108903D0 (en) | 2000-10-05 | 2001-05-30 | Aventis Pharm Prod Inc | Novel crystalline forms of a factor Xa inhibitor |
| KR101509829B1 (ko) * | 2007-05-02 | 2015-04-06 | 포톨라 파마슈티컬스, 인코포레이티드 | 혈소판 ａｄｐ 수용체 억제제로 작용하는 화합물을 이용한 병용요법 |
| CA2766533A1 (en) * | 2009-07-29 | 2011-02-03 | Sanofi | Otamixaban for treatment of elderly and renal impaired non-st elevation myocardial infarction patients |
-
2012
- 2012-03-27 RU RU2013148005/04A patent/RU2597423C2/ru not_active IP Right Cessation
- 2012-03-27 JP JP2014501569A patent/JP5959617B2/ja active Active
- 2012-03-27 KR KR1020137028416A patent/KR101852226B1/ko not_active Expired - Fee Related
- 2012-03-27 AU AU2012234325A patent/AU2012234325B2/en not_active Ceased
- 2012-03-27 DK DK12711858.6T patent/DK2691371T3/da active
- 2012-03-27 US US14/008,332 patent/US8993602B2/en active Active
- 2012-03-27 ES ES12711858.6T patent/ES2539236T3/es active Active
- 2012-03-27 WO PCT/EP2012/055364 patent/WO2012130821A1/en not_active Ceased
- 2012-03-27 SI SI201230219T patent/SI2691371T1/sl unknown
- 2012-03-27 MX MX2013011266A patent/MX2013011266A/es active IP Right Grant
- 2012-03-27 HR HRP20150613TT patent/HRP20150613T1/hr unknown
- 2012-03-27 CA CA2830965A patent/CA2830965C/en not_active Expired - Fee Related
- 2012-03-27 MY MYPI2013003459A patent/MY161396A/en unknown
- 2012-03-27 BR BR112013025105A patent/BR112013025105A2/pt not_active Application Discontinuation
- 2012-03-27 EP EP12711858.6A patent/EP2691371B1/en active Active
- 2012-03-27 CN CN201280026534.0A patent/CN103562183B/zh active Active
- 2012-03-27 PT PT127118586T patent/PT2691371E/pt unknown
- 2012-03-27 SG SG2013071766A patent/SG193612A1/en unknown
- 2012-03-27 PL PL12711858T patent/PL2691371T3/pl unknown
-
2013
- 2013-09-29 IL IL228574A patent/IL228574A/en active IP Right Grant
-
2015
- 2015-06-17 CY CY20151100521T patent/CY1116659T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2013011266A (es) | 2014-03-27 |
| KR101852226B1 (ko) | 2018-04-25 |
| JP2014509622A (ja) | 2014-04-21 |
| AU2012234325A1 (en) | 2013-10-17 |
| HK1189584A1 (en) | 2014-06-13 |
| DK2691371T3 (da) | 2015-06-22 |
| WO2012130821A1 (en) | 2012-10-04 |
| EP2691371B1 (en) | 2015-03-18 |
| IL228574A0 (en) | 2013-12-31 |
| PT2691371E (pt) | 2015-07-20 |
| BR112013025105A2 (pt) | 2017-06-06 |
| CN103562183B (zh) | 2015-12-23 |
| CA2830965C (en) | 2019-04-09 |
| CN103562183A (zh) | 2014-02-05 |
| ES2539236T3 (es) | 2015-06-29 |
| SG193612A1 (en) | 2013-11-29 |
| US20140024684A1 (en) | 2014-01-23 |
| US8993602B2 (en) | 2015-03-31 |
| JP5959617B2 (ja) | 2016-08-02 |
| SI2691371T1 (sl) | 2015-07-31 |
| RU2013148005A (ru) | 2015-05-10 |
| EP2691371A1 (en) | 2014-02-05 |
| IL228574A (en) | 2015-07-30 |
| MY161396A (en) | 2017-04-14 |
| PL2691371T3 (pl) | 2015-08-31 |
| CA2830965A1 (en) | 2012-10-04 |
| CY1116659T1 (el) | 2017-03-15 |
| AU2012234325B2 (en) | 2016-08-11 |
| KR20140022851A (ko) | 2014-02-25 |
| RU2597423C2 (ru) | 2016-09-10 |
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