SI2691371T1 - Sol benzojske kisline otamiksabana - Google Patents
Sol benzojske kisline otamiksabanaInfo
- Publication number
- SI2691371T1 SI2691371T1 SI201230219T SI201230219T SI2691371T1 SI 2691371 T1 SI2691371 T1 SI 2691371T1 SI 201230219 T SI201230219 T SI 201230219T SI 201230219 T SI201230219 T SI 201230219T SI 2691371 T1 SI2691371 T1 SI 2691371T1
- Authority
- SI
- Slovenia
- Prior art keywords
- otamixaban
- benzoic acid
- acid salt
- salt
- benzoic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11305348 | 2011-03-29 | ||
US201161500342P | 2011-06-23 | 2011-06-23 | |
PCT/EP2012/055364 WO2012130821A1 (en) | 2011-03-29 | 2012-03-27 | Benzoic acid salt of otamixaban |
EP12711858.6A EP2691371B1 (en) | 2011-03-29 | 2012-03-27 | Benzoic acid salt of otamixaban |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2691371T1 true SI2691371T1 (sl) | 2015-07-31 |
Family
ID=44065390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201230219T SI2691371T1 (sl) | 2011-03-29 | 2012-03-27 | Sol benzojske kisline otamiksabana |
Country Status (22)
Country | Link |
---|---|
US (1) | US8993602B2 (sl) |
EP (1) | EP2691371B1 (sl) |
JP (1) | JP5959617B2 (sl) |
KR (1) | KR101852226B1 (sl) |
CN (1) | CN103562183B (sl) |
AU (1) | AU2012234325B2 (sl) |
BR (1) | BR112013025105A2 (sl) |
CA (1) | CA2830965C (sl) |
CY (1) | CY1116659T1 (sl) |
DK (1) | DK2691371T3 (sl) |
ES (1) | ES2539236T3 (sl) |
HK (1) | HK1189584A1 (sl) |
HR (1) | HRP20150613T1 (sl) |
IL (1) | IL228574A (sl) |
MX (1) | MX2013011266A (sl) |
MY (1) | MY161396A (sl) |
PL (1) | PL2691371T3 (sl) |
PT (1) | PT2691371E (sl) |
RU (1) | RU2597423C2 (sl) |
SG (1) | SG193612A1 (sl) |
SI (1) | SI2691371T1 (sl) |
WO (1) | WO2012130821A1 (sl) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2012234323A1 (en) | 2011-03-29 | 2013-10-17 | Sanofi | Otamixaban formulations with improved stability |
CN106565698B (zh) * | 2016-08-15 | 2019-03-08 | 南京帕隆材料科技有限公司 | 取代噻唑类衍生物及其制备方法和用途 |
CN106518859B (zh) * | 2016-08-15 | 2019-01-18 | 南京帕隆材料科技有限公司 | 噻唑类衍生物及其制备方法和用途 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5424334A (en) | 1991-12-19 | 1995-06-13 | G. D. Searle & Co. | Peptide mimetic compounds useful as platelet aggregation inhibitors |
US6080767A (en) * | 1996-01-02 | 2000-06-27 | Aventis Pharmaceuticals Products Inc. | Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides |
RO117913B1 (ro) * | 1996-01-02 | 2002-09-30 | Aventis Pharmaceuticals Inc. | Derivaţi de n-[(amino-(imino)metil)fenil]propil amide substituite, compoziţie farmaceutică care îi conţine şi metodă de tratament |
GB0108903D0 (en) * | 2000-10-05 | 2001-05-30 | Aventis Pharm Prod Inc | Novel crystalline forms of a factor Xa inhibitor |
CA2684722A1 (en) * | 2007-05-02 | 2008-11-13 | Portola Pharmaceuticals, Inc. | Combination therapy with a compound acting as a platelet adp receptor inhibitor |
RU2542455C2 (ru) | 2009-07-29 | 2015-02-20 | Санофи | Отамиксабан для лечения инфаркта миокарда без подъема сегмента st у пациентов пожилого возраста и пациентов с нарушенной функцией почек |
-
2012
- 2012-03-27 SI SI201230219T patent/SI2691371T1/sl unknown
- 2012-03-27 SG SG2013071766A patent/SG193612A1/en unknown
- 2012-03-27 DK DK12711858.6T patent/DK2691371T3/da active
- 2012-03-27 MY MYPI2013003459A patent/MY161396A/en unknown
- 2012-03-27 WO PCT/EP2012/055364 patent/WO2012130821A1/en active Application Filing
- 2012-03-27 CN CN201280026534.0A patent/CN103562183B/zh active Active
- 2012-03-27 RU RU2013148005/04A patent/RU2597423C2/ru not_active IP Right Cessation
- 2012-03-27 PT PT127118586T patent/PT2691371E/pt unknown
- 2012-03-27 JP JP2014501569A patent/JP5959617B2/ja active Active
- 2012-03-27 PL PL12711858T patent/PL2691371T3/pl unknown
- 2012-03-27 AU AU2012234325A patent/AU2012234325B2/en not_active Ceased
- 2012-03-27 US US14/008,332 patent/US8993602B2/en active Active
- 2012-03-27 EP EP12711858.6A patent/EP2691371B1/en active Active
- 2012-03-27 KR KR1020137028416A patent/KR101852226B1/ko active IP Right Grant
- 2012-03-27 MX MX2013011266A patent/MX2013011266A/es active IP Right Grant
- 2012-03-27 BR BR112013025105A patent/BR112013025105A2/pt not_active Application Discontinuation
- 2012-03-27 ES ES12711858.6T patent/ES2539236T3/es active Active
- 2012-03-27 CA CA2830965A patent/CA2830965C/en not_active Expired - Fee Related
-
2013
- 2013-09-29 IL IL228574A patent/IL228574A/en active IP Right Grant
-
2014
- 2014-03-17 HK HK14102611.9A patent/HK1189584A1/xx not_active IP Right Cessation
-
2015
- 2015-06-08 HR HRP20150613TT patent/HRP20150613T1/hr unknown
- 2015-06-17 CY CY20151100521T patent/CY1116659T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2830965A1 (en) | 2012-10-04 |
AU2012234325B2 (en) | 2016-08-11 |
CN103562183B (zh) | 2015-12-23 |
AU2012234325A1 (en) | 2013-10-17 |
MX2013011266A (es) | 2014-03-27 |
US8993602B2 (en) | 2015-03-31 |
US20140024684A1 (en) | 2014-01-23 |
JP5959617B2 (ja) | 2016-08-02 |
CN103562183A (zh) | 2014-02-05 |
JP2014509622A (ja) | 2014-04-21 |
HRP20150613T1 (hr) | 2015-07-17 |
RU2597423C2 (ru) | 2016-09-10 |
PL2691371T3 (pl) | 2015-08-31 |
KR20140022851A (ko) | 2014-02-25 |
DK2691371T3 (da) | 2015-06-22 |
IL228574A (en) | 2015-07-30 |
BR112013025105A2 (pt) | 2017-06-06 |
KR101852226B1 (ko) | 2018-04-25 |
WO2012130821A1 (en) | 2012-10-04 |
IL228574A0 (en) | 2013-12-31 |
RU2013148005A (ru) | 2015-05-10 |
PT2691371E (pt) | 2015-07-20 |
EP2691371A1 (en) | 2014-02-05 |
MY161396A (en) | 2017-04-14 |
EP2691371B1 (en) | 2015-03-18 |
CA2830965C (en) | 2019-04-09 |
HK1189584A1 (en) | 2014-06-13 |
ES2539236T3 (es) | 2015-06-29 |
SG193612A1 (en) | 2013-11-29 |
CY1116659T1 (el) | 2017-03-15 |
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