HRP20150596T1 - Sastav viralnih inhibitora za in vivo terapeutsku upotrebu - Google Patents
Sastav viralnih inhibitora za in vivo terapeutsku upotrebu Download PDFInfo
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- HRP20150596T1 HRP20150596T1 HRP20150596TT HRP20150596T HRP20150596T1 HR P20150596 T1 HRP20150596 T1 HR P20150596T1 HR P20150596T T HRP20150596T T HR P20150596TT HR P20150596 T HRP20150596 T HR P20150596T HR P20150596 T1 HRP20150596 T1 HR P20150596T1
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- 239000000203 mixture Substances 0.000 title claims 16
- 239000003443 antiviral agent Substances 0.000 title claims 3
- 238000001727 in vivo Methods 0.000 title claims 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 27
- 201000010099 disease Diseases 0.000 claims 16
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 16
- 208000010201 Exanthema Diseases 0.000 claims 7
- 201000005884 exanthem Diseases 0.000 claims 7
- 206010037844 rash Diseases 0.000 claims 7
- 208000006454 hepatitis Diseases 0.000 claims 5
- 206010037660 Pyrexia Diseases 0.000 claims 4
- 208000009714 Severe Dengue Diseases 0.000 claims 4
- 208000023504 respiratory system disease Diseases 0.000 claims 4
- 206010012310 Dengue fever Diseases 0.000 claims 3
- 201000004624 Dermatitis Diseases 0.000 claims 3
- 208000005577 Gastroenteritis Diseases 0.000 claims 3
- 241000700605 Viruses Species 0.000 claims 3
- 230000001154 acute effect Effects 0.000 claims 3
- 206010014599 encephalitis Diseases 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 201000006747 infectious mononucleosis Diseases 0.000 claims 3
- 208000006820 Arthralgia Diseases 0.000 claims 2
- 206010008909 Chronic Hepatitis Diseases 0.000 claims 2
- 206010010741 Conjunctivitis Diseases 0.000 claims 2
- 241000450599 DNA viruses Species 0.000 claims 2
- 206010012735 Diarrhoea Diseases 0.000 claims 2
- 208000007514 Herpes zoster Diseases 0.000 claims 2
- 206010022678 Intestinal infections Diseases 0.000 claims 2
- 206010035664 Pneumonia Diseases 0.000 claims 2
- 208000012873 acute gastroenteritis Diseases 0.000 claims 2
- 208000010668 atopic eczema Diseases 0.000 claims 2
- 201000002950 dengue hemorrhagic fever Diseases 0.000 claims 2
- 201000009892 dengue shock syndrome Diseases 0.000 claims 2
- 244000309457 enveloped RNA virus Species 0.000 claims 2
- 230000003176 fibrotic effect Effects 0.000 claims 2
- 230000002458 infectious effect Effects 0.000 claims 2
- 206010022000 influenza Diseases 0.000 claims 2
- 208000017169 kidney disease Diseases 0.000 claims 2
- 230000003902 lesion Effects 0.000 claims 2
- 230000002085 persistent effect Effects 0.000 claims 2
- 230000000241 respiratory effect Effects 0.000 claims 2
- 208000011580 syndromic disease Diseases 0.000 claims 2
- 208000030507 AIDS Diseases 0.000 claims 1
- 208000003829 American Hemorrhagic Fever Diseases 0.000 claims 1
- 201000009695 Argentine hemorrhagic fever Diseases 0.000 claims 1
- 208000034200 Bolivian hemorrhagic fever Diseases 0.000 claims 1
- 208000014644 Brain disease Diseases 0.000 claims 1
- 201000010424 Brazilian hemorrhagic fever Diseases 0.000 claims 1
- 201000006082 Chickenpox Diseases 0.000 claims 1
- 206010010071 Coma Diseases 0.000 claims 1
- 206010011878 Deafness Diseases 0.000 claims 1
- 241001533413 Deltavirus Species 0.000 claims 1
- 208000001490 Dengue Diseases 0.000 claims 1
- 208000032274 Encephalopathy Diseases 0.000 claims 1
- 208000004232 Enteritis Diseases 0.000 claims 1
- 241001529459 Enterovirus A71 Species 0.000 claims 1
- 241000693328 Enterovirus B69 Species 0.000 claims 1
- 241000991587 Enterovirus C Species 0.000 claims 1
- 208000035751 Epidemic nephropathy Diseases 0.000 claims 1
- 206010066919 Epidemic polyarthritis Diseases 0.000 claims 1
- 206010015108 Epstein-Barr virus infection Diseases 0.000 claims 1
- 201000005866 Exanthema Subitum Diseases 0.000 claims 1
- 208000007212 Foot-and-Mouth Disease Diseases 0.000 claims 1
- 241000710198 Foot-and-mouth disease virus Species 0.000 claims 1
- 206010061192 Haemorrhagic fever Diseases 0.000 claims 1
- 241001466963 Hawaii calicivirus Species 0.000 claims 1
- 206010019233 Headaches Diseases 0.000 claims 1
- 208000032982 Hemorrhagic Fever with Renal Syndrome Diseases 0.000 claims 1
- 201000006219 Herpangina Diseases 0.000 claims 1
- 208000000903 Herpes simplex encephalitis Diseases 0.000 claims 1
- 208000037018 Herpes simplex virus encephalitis Diseases 0.000 claims 1
- 241000699727 Human echovirus Species 0.000 claims 1
- 241000709694 Human parechovirus 1 Species 0.000 claims 1
- 241001214603 Human rhinovirus A1 Species 0.000 claims 1
- 241000178583 Human rhinovirus B3 Species 0.000 claims 1
- 208000019637 Infantile Diarrhea Diseases 0.000 claims 1
- 206010021882 Infections and infestations congenital Diseases 0.000 claims 1
- 208000012659 Joint disease Diseases 0.000 claims 1
- 208000007766 Kaposi sarcoma Diseases 0.000 claims 1
- 206010023424 Kidney infection Diseases 0.000 claims 1
- 208000008771 Lymphadenopathy Diseases 0.000 claims 1
- 235000019493 Macadamia oil Nutrition 0.000 claims 1
- 201000005505 Measles Diseases 0.000 claims 1
- 201000009906 Meningitis Diseases 0.000 claims 1
- 208000005647 Mumps Diseases 0.000 claims 1
- 208000000112 Myalgia Diseases 0.000 claims 1
- 208000009525 Myocarditis Diseases 0.000 claims 1
- 241000714209 Norwalk virus Species 0.000 claims 1
- 208000001388 Opportunistic Infections Diseases 0.000 claims 1
- 206010048685 Oral infection Diseases 0.000 claims 1
- 206010068319 Oropharyngeal pain Diseases 0.000 claims 1
- 206010033645 Pancreatitis Diseases 0.000 claims 1
- 206010033799 Paralysis Diseases 0.000 claims 1
- 208000037581 Persistent Infection Diseases 0.000 claims 1
- 201000007100 Pharyngitis Diseases 0.000 claims 1
- 206010036030 Polyarthritis Diseases 0.000 claims 1
- 102000029797 Prion Human genes 0.000 claims 1
- 108091000054 Prion Proteins 0.000 claims 1
- 206010037596 Pyelonephritis Diseases 0.000 claims 1
- 206010037742 Rabies Diseases 0.000 claims 1
- 206010037868 Rash maculo-papular Diseases 0.000 claims 1
- 208000007313 Reproductive Tract Infections Diseases 0.000 claims 1
- 206010057190 Respiratory tract infections Diseases 0.000 claims 1
- 241000369753 Sapporo virus Species 0.000 claims 1
- 201000003176 Severe Acute Respiratory Syndrome Diseases 0.000 claims 1
- 241000509413 Snow Mountain virus Species 0.000 claims 1
- 241000714208 Southampton virus Species 0.000 claims 1
- 208000037065 Subacute sclerosing leukoencephalitis Diseases 0.000 claims 1
- 206010042297 Subacute sclerosing panencephalitis Diseases 0.000 claims 1
- 206010042566 Superinfection Diseases 0.000 claims 1
- 208000025865 Ulcer Diseases 0.000 claims 1
- 206010046980 Varicella Diseases 0.000 claims 1
- 201000009693 Venezuelan hemorrhagic fever Diseases 0.000 claims 1
- 231100000354 acute hepatitis Toxicity 0.000 claims 1
- 206010003246 arthritis Diseases 0.000 claims 1
- 206010064097 avian influenza Diseases 0.000 claims 1
- 239000002199 base oil Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000019425 cirrhosis of liver Diseases 0.000 claims 1
- 231100000895 deafness Toxicity 0.000 claims 1
- 208000025729 dengue disease Diseases 0.000 claims 1
- 239000000645 desinfectant Substances 0.000 claims 1
- 230000006806 disease prevention Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 201000010582 ecthyma Diseases 0.000 claims 1
- 201000006061 fatal familial insomnia Diseases 0.000 claims 1
- 210000004907 gland Anatomy 0.000 claims 1
- 231100000869 headache Toxicity 0.000 claims 1
- 208000016354 hearing loss disease Diseases 0.000 claims 1
- 230000002949 hemolytic effect Effects 0.000 claims 1
- 231100000283 hepatitis Toxicity 0.000 claims 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 claims 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 claims 1
- 208000033065 inborn errors of immunity Diseases 0.000 claims 1
- 210000003000 inclusion body Anatomy 0.000 claims 1
- 206010023332 keratitis Diseases 0.000 claims 1
- 201000010666 keratoconjunctivitis Diseases 0.000 claims 1
- 201000002364 leukopenia Diseases 0.000 claims 1
- 231100001022 leukopenia Toxicity 0.000 claims 1
- 208000018555 lymphatic system disease Diseases 0.000 claims 1
- 239000010469 macadamia oil Substances 0.000 claims 1
- 208000012965 maculopapular rash Diseases 0.000 claims 1
- 210000004400 mucous membrane Anatomy 0.000 claims 1
- 208000010805 mumps infectious disease Diseases 0.000 claims 1
- 208000013465 muscle pain Diseases 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 235000019198 oils Nutrition 0.000 claims 1
- 239000004006 olive oil Substances 0.000 claims 1
- 235000008390 olive oil Nutrition 0.000 claims 1
- 201000005737 orchitis Diseases 0.000 claims 1
- 208000030428 polyarticular arthritis Diseases 0.000 claims 1
- 208000028529 primary immunodeficiency disease Diseases 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 claims 1
- 201000010153 skin papilloma Diseases 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
- 208000003265 stomatitis Diseases 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 230000036269 ulceration Effects 0.000 claims 1
- 208000005925 vesicular stomatitis Diseases 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
- 230000004580 weight loss Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aldehyde or keto groups, or thio analogues thereof, directly attached to an aromatic ring system, e.g. acetophenone; Derivatives thereof, e.g. acetals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/24—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
- C07C49/245—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings
- C07C49/248—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings having unsaturation outside the aromatic rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Claims (12)
1. Sastav, koji obuhvaća farmaceutski djelotvornu koncentraciju spoja formule A
[image]
i/ili spoj formule B
[image]
i/ili spoj formule C
[image]
za primjenu, kao lijek.
2. Sastav, koji obuhvaća farmaceutski djelotvornu koncentraciju spoja formule A
[image]
i/ili spoja formule B
[image]
i/ili spoja formule C
[image]
za primjenu in-vivo, kod liječenja i prevencije bolesti, koje budu prouzročene putem začahurenih DNA virusa, nezačahurenih DNA virusa, začahurenih RNA virusa i nezačahurenih RNA virusa, pri čemu su bolesti odabrane iz skupine, koja se sastoji od: (bronho)pneumonije, trodnevnog eksantema s vrućicom, akutnog ili kroničnog hepatitisa, akutne vrućice, akutnog gastroenetritisa, koji budu prouzročeni sojevima kao „Desert-Shield-, Lordsdale-, Mexiko-, Norwalk-, Hawaii-, Snow-Mountain odnosno Southampton-virusa, akutnog gastroenteritisa, koji budu prouzročeni preko sojeva kao Houston/86-, Houston/90-, London-29845-, Manchester-, Parkville- odnosno Sapporo-virusa, akutnog hepatitisa, akutnog sindroma nestanka zraka, SIDE, argentinske hemoragijske groznice, artralgije, ptičje gripe, bolivijske hemoragijske groznice, brazilske hemoragijske groznice, vodenih kozica, kroničnog hepatitisa, kome, jednostavnih prehlada, simptoma jadnostavnih prehlada, kongenitalnih infekcija, konjuktivitisa, zaraznog ekthyma, zaraznog pustuloznog dermatitisa, kriptičnih enteričnih infekcija, preko citomegalivirusa uzrokovane mononukleoze, hemoragijske Dengue groznice (DHF), Dengue-šok-sindroma (DSS), dijareje, ekcema, ekcem herpaticum, encefalitis, encefalopatija, enteritis, epidemička nefropatija, epidemični poliartritis, und epidemički eksantem, epidenodisplazija veruciformis, infekcija Epstein-Barr virusom, eksantem, eksantem kod djece, letalna obiteljska insomnija, fibrozni encefalitis, fibrozna oboljenja, vrućica, bolesti u vezi sa ranijim humanim Echo-virusom 22, 23, gastroenteritis, infekcije želuca i crijeva, intracitoplazmatska inkluzijska tijela, infekcije genitalnog trakta, hemolitička kriza kod osoba s oboljenjima uzrokovanim Sichel stanicama, glavobolje, hemoragijska groznica, hemoragijska groznica s renalnim sindromom, herpetički encefalitis, oboljenja u vezi sa humanim Coxsacki virusom, oboljenja u vezi sa humanim Coxsacki virusom B1-6, oboljenja u vezi sa humanim Echo virusom 1-7, 9, 11-21, 24-27, 29-33, oboljenja u vezi sa humanim entero virusom 69, oboljenja u vezi s humanim entero virusom 71 (slinavka i šap), oboljenja u vezi sa humanim hepatitis virusom A (HHAV), oboljenja u vezi sa humanim polio virusom, oboljenja u vezi sa humanim rino virusom 1, 2, 7, 9, 11, 15, 16, 21, 29, 36, 39, 49, 50, 58, 62, 65, 85, 89, hiperakutna oboljenja dišnih putova, oboljenja u vezi sa humanim rino virusom 3, 14, 72, hiperakutna oboljenja dišnih putova, sindrom imunodeficijencije, infantilna dijareja, infekcije s Dengue serotipom (1-4), infekcijska mononukleoza, bolesti zglobova, Kaposi sarkom, keratokonjuktivitis, lezije na koži, leukopenija, ciroza jetre, infekcije unutarnjih dišnih putova, limfadenopatija, makulopapulozni osip, ospice, meningitis, mononukleoza (Pfeifferova vrućica žlijezda), mumps, bolovi mišića, miokarditis, nefropatija, nefropatija kod transplantiranih pacijenata, gluhoća, oportunističke infekcije, oralne infekcije, orhitis, pankreatitis, pandemije, papilom, paraliza, perzistirajuće infekcije bubrega, perzistirajuće infekcije, perzistirajuća limfopatija, faringealni konjuktivitis, pneumonija, primarni hepatocelularni karcinom, pulmonalni sindrom, bjesnoća, osip, recidivirajuće epidemije dišnih putova, oboljenja dišnih putova, bolest dišnih putova, Roseola infantum, snažna zimica, artralgija, snažni akutni respiratorni sindrom, jaki encefalitis, zoster, Sechster oboljenje, membranske lezije kože i sluznice, oboljenja kod mršavljenja, bolovi grla, subakutni sklerozirajući panencefalitis, superinfekcije uzrokovane delta virusom, ulceracije, oboljenja gornjih dišnih putova, venezolanska hemoragijska groznica, vezikularni faringitis, vezikularni stomatitis sa eksantemom, viralni poliartritis i osip, viralne bradavice, vodena dijareja, slabost, Herpes Zoster, odnosno gripa (influenca).
3. Sastav za primjenu prema zahtjevima 1 ili 2, naznačen time da su izdvojeni spojevi iz skupine, koji se sastoje od:
Spoj formule A sam ili
Spoj formule B sam ili
Spoj formule C sam ili
Spoj formule A i spoj formule B ili
Spoj formule A i spoj formule C ili
Spoj formule B i spoj formule C ili
Spoj formule A i spoj formule B i spoj formule C.
4. Sastav za primjenu prema zahtjevima 1 ili 2, naznačen time da će svaki spoj, u dozi većoj ili jednakoj od 0,1 mg po aplikaciji, biti apliciran.
5. Sastav za primjenu prema zahtjevu 4, naznačen time da će svaki spoj, u dozi između 0,1 mg i 5000 mg po aplikaciji, biti apliciran.
6. Sastav za primjenu prema zahtjevu 4 ili 5, naznačen time da će doza biti aplicirana najmanje jednom na dan.
7. Sastav za primjenu prema zahtjevu 1 ili 2 ili 3, naznačen time da će kao bazično ulje biti dodano ulje kao maslinovo ulje ili makadamija ulje.
8. Sastav za primjenu prema zahtjevu 2, naznačen time da će sastav biti primijenjen kao profilaktičko sredstvo.
9. Sastav za primjenu prema zahtjevu 2, naznačen time da će sastav biti primijenjen kao viralni inhibitor, unutar tijela.
10. Sastav za primjenu prema zahtjevu 2, naznačen time da će sastav biti primijenjen oralno, topički, putem inhalacije, putem supozitorija, intravenozno, subkutano, intramuskulano ili preko flastera.
11. Primjena sastava, koji obuhvaća farmaceutski djelotvornu koncentraciju spoja
formule A
[image]
i/ili spoja formule B
[image]
i/ili spoja formule C
[image]
kao definfekcijskog sredstva.
12. Ne-terapeutska primjena sastava, koji obuhvaća farmaceutski djelotvornu koncentraciju spoja formule A
[image]
i/ili spoja formule B
[image]
i/ili spoja formule C
[image]
kao viralnog inhibitora izvan tijela.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2011/054758 WO2011117424A1 (en) | 2010-03-26 | 2011-03-28 | Viral inhibitor compositions for in vivo therapeutic use comprising a combination of (-) -carvone, geraniol and a further essential oil component |
| PCT/EP2011/066746 WO2012038553A1 (en) | 2011-03-28 | 2011-09-27 | Viral inhibitor composition for in vivo therapeutic use |
| EP11761085.7A EP2691088B1 (en) | 2011-03-28 | 2011-09-27 | Viral inhibitor composition for in vivo therapeutic use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20150596T1 true HRP20150596T1 (hr) | 2015-08-14 |
Family
ID=44677899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20150596TT HRP20150596T1 (hr) | 2011-03-28 | 2015-06-03 | Sastav viralnih inhibitora za in vivo terapeutsku upotrebu |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US9315448B2 (hr) |
| EP (1) | EP2691088B1 (hr) |
| JP (1) | JP5701445B2 (hr) |
| KR (1) | KR101818286B1 (hr) |
| CN (1) | CN103458883B (hr) |
| AU (1) | AU2011306879B2 (hr) |
| BR (1) | BR112013024457A2 (hr) |
| CA (1) | CA2830703C (hr) |
| CO (1) | CO6771455A2 (hr) |
| DK (1) | DK2691088T3 (hr) |
| EA (1) | EA025610B1 (hr) |
| ES (1) | ES2538011T3 (hr) |
| HK (1) | HK1188715A1 (hr) |
| HR (1) | HRP20150596T1 (hr) |
| IL (1) | IL228444A (hr) |
| MA (1) | MA34975B1 (hr) |
| MX (1) | MX2013011242A (hr) |
| NZ (1) | NZ615613A (hr) |
| PL (1) | PL2691088T3 (hr) |
| PT (1) | PT2691088E (hr) |
| RS (1) | RS54022B1 (hr) |
| SG (1) | SG193426A1 (hr) |
| SI (1) | SI2691088T1 (hr) |
| SM (1) | SMT201500131B (hr) |
| UA (1) | UA110512C2 (hr) |
| WO (1) | WO2012038553A1 (hr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112280750B (zh) * | 2020-10-22 | 2022-11-01 | 山东农业大学 | 具有跨种传播能力的新型鹅星状病毒及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU78955A1 (de) | 1978-01-27 | 1979-09-06 | Chimicasa Gmbh | Verfahren zur inaktivierung von viren |
| US4902678A (en) | 1982-02-12 | 1990-02-20 | Syntex (U.S.A.) Inc. | Anti-viral compositions |
| US5128353A (en) * | 1985-06-20 | 1992-07-07 | University Of Florida | Anti-neoplastic, anti-viral and ribonucleotide reductase activity affecting pharmaceutical compositions and methods of treatment |
| US5856364A (en) | 1991-03-01 | 1999-01-05 | Warner Lambert Company | Therapeutic antiviral-wound healing compositions and methods for preparing and using same |
| WO2002056879A1 (en) * | 2001-01-03 | 2002-07-25 | Medpharma Plc | Use of terpenes for the treatment of digestive tract infections |
| US20040071757A1 (en) | 2001-11-20 | 2004-04-15 | David Rolf | Inhalation antiviral patch |
-
2011
- 2011-09-27 SG SG2013068671A patent/SG193426A1/en unknown
- 2011-09-27 WO PCT/EP2011/066746 patent/WO2012038553A1/en active Application Filing
- 2011-09-27 EP EP11761085.7A patent/EP2691088B1/en active Active
- 2011-09-27 KR KR1020137027360A patent/KR101818286B1/ko active IP Right Grant
- 2011-09-27 MX MX2013011242A patent/MX2013011242A/es active IP Right Grant
- 2011-09-27 NZ NZ615613A patent/NZ615613A/en unknown
- 2011-09-27 ES ES11761085.7T patent/ES2538011T3/es active Active
- 2011-09-27 JP JP2014501454A patent/JP5701445B2/ja active Active
- 2011-09-27 CN CN201180069698.7A patent/CN103458883B/zh active Active
- 2011-09-27 PT PT117610857T patent/PT2691088E/pt unknown
- 2011-09-27 EA EA201370181A patent/EA025610B1/ru unknown
- 2011-09-27 CA CA2830703A patent/CA2830703C/en active Active
- 2011-09-27 US US14/008,092 patent/US9315448B2/en active Active
- 2011-09-27 BR BR112013024457-7A patent/BR112013024457A2/pt not_active Application Discontinuation
- 2011-09-27 DK DK11761085.7T patent/DK2691088T3/en active
- 2011-09-27 AU AU2011306879A patent/AU2011306879B2/en active Active
- 2011-09-27 MA MA36264A patent/MA34975B1/fr unknown
- 2011-09-27 UA UAA201311023A patent/UA110512C2/ru unknown
- 2011-09-27 SI SI201130509T patent/SI2691088T1/sl unknown
- 2011-09-27 PL PL11761085T patent/PL2691088T3/pl unknown
- 2011-09-27 RS RS20150382A patent/RS54022B1/en unknown
-
2013
- 2013-09-15 IL IL228444A patent/IL228444A/en active IP Right Grant
- 2013-09-25 CO CO13228235A patent/CO6771455A2/es unknown
-
2014
- 2014-02-24 HK HK14101759.3A patent/HK1188715A1/xx unknown
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2015
- 2015-06-03 HR HRP20150596TT patent/HRP20150596T1/hr unknown
- 2015-06-09 SM SM201500131T patent/SMT201500131B/xx unknown
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