HRP20150328T1 - Bakterijski dobivene, intaktne mini-stanice koje obuhvaä†aju funkcionalnu nukleinsku kiselinu, bez plazmida, za in vivo dopremu do stanica sisavaca - Google Patents

Bakterijski dobivene, intaktne mini-stanice koje obuhvaä†aju funkcionalnu nukleinsku kiselinu, bez plazmida, za in vivo dopremu do stanica sisavaca

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Publication number
HRP20150328T1
HRP20150328T1 HRP20150328TT HRP20150328T HRP20150328T1 HR P20150328 T1 HRP20150328 T1 HR P20150328T1 HR P20150328T T HRP20150328T T HR P20150328TT HR P20150328 T HRP20150328 T HR P20150328T HR P20150328 T1 HRP20150328 T1 HR P20150328T1
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HR
Croatia
Prior art keywords
stations
bacterialally
vival
plasmid
mammalian
Prior art date
Application number
HRP20150328TT
Other languages
English (en)
Croatian (hr)
Inventor
Himanshu Brahmbhatt
Jennifer Macdiarmid
Toby Hulf
Original Assignee
Engeneic Molecular Delivery Pty Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Engeneic Molecular Delivery Pty Ltd. filed Critical Engeneic Molecular Delivery Pty Ltd.
Publication of HRP20150328T1 publication Critical patent/HRP20150328T1/hr

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0091—Purification or manufacturing processes for gene therapy compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
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HRP20150328TT 2007-03-30 2008-03-26 Bakterijski dobivene, intaktne mini-stanice koje obuhvaä†aju funkcionalnu nukleinsku kiselinu, bez plazmida, za in vivo dopremu do stanica sisavaca HRP20150328T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90907407P 2007-03-30 2007-03-30
EP08828079.7A EP2145002B1 (en) 2007-03-30 2008-03-26 Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells
PCT/IB2008/002984 WO2009027830A2 (en) 2007-03-30 2008-03-26 Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells

Publications (1)

Publication Number Publication Date
HRP20150328T1 true HRP20150328T1 (hr) 2015-05-22

Family

ID=40386454

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20150328TT HRP20150328T1 (hr) 2007-03-30 2008-03-26 Bakterijski dobivene, intaktne mini-stanice koje obuhvaä†aju funkcionalnu nukleinsku kiselinu, bez plazmida, za in vivo dopremu do stanica sisavaca
HRP20170662TT HRP20170662T1 (hr) 2007-03-30 2017-05-02 Nedirnute ministanice, izvedene iz bakterija, koje sadrže regulatornu rnk

Family Applications After (1)

Application Number Title Priority Date Filing Date
HRP20170662TT HRP20170662T1 (hr) 2007-03-30 2017-05-02 Nedirnute ministanice, izvedene iz bakterija, koje sadrže regulatornu rnk

Country Status (17)

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EP (5) EP3564372A1 (enExample)
JP (1) JP5167338B2 (enExample)
CN (2) CN105854029B (enExample)
AU (1) AU2008291833B2 (enExample)
CA (3) CA2933978C (enExample)
CY (1) CY1119031T1 (enExample)
DK (2) DK2145002T3 (enExample)
ES (2) ES2534435T3 (enExample)
HR (2) HRP20150328T1 (enExample)
LT (1) LT2865755T (enExample)
MX (1) MX2009010411A (enExample)
NZ (1) NZ580487A (enExample)
PL (2) PL2865755T3 (enExample)
PT (2) PT2865755T (enExample)
SG (2) SG10201507969PA (enExample)
SI (2) SI2145002T1 (enExample)
WO (1) WO2009027830A2 (enExample)

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SG10201507969PA (en) * 2007-03-30 2015-10-29 Engeneic Molecular Delivery Pty Ltd Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells
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SI2790668T1 (sl) 2011-12-13 2021-01-29 Engeneic Molecular Delivery Pty Ltd. Iz bakterij izhajajoče intaktne minicelice za dostavo terapevtskih sredstev v možganske tumorje
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SG11201702627UA (en) * 2014-10-03 2017-04-27 Engeneic Molecular Delivery Pty Ltd Enhanced loading of intact, bacterially derived vesicles with small molecule compounds
EP3522935A4 (en) * 2016-10-06 2020-05-13 EnGeneIC Molecular Delivery Pty Ltd. BACTERIAL MINICELLS FOR THE DELIVERY OF NUCLEIC ACID ADJUVANTS AND METHODS OF USE THEREOF
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US11649265B2 (en) 2017-04-28 2023-05-16 Agrospheres, Inc. Compositions and methods for the encapsulation and scalable delivery of agrochemicals
CA3073449A1 (en) 2017-09-25 2019-03-28 Agrospheres, Inc. Compositions and methods for scalable production and delivery of biologicals
EP3826654A4 (en) 2018-07-23 2022-07-06 EnGeneIC Molecular Delivery Pty Ltd COMPOSITIONS COMPRISING MINICELLS OF BACTERIAL ORIGIN AND THEIR METHODS OF USE
SG11202107306WA (en) 2019-01-04 2021-08-30 Engeneic Molecular Delivery Pty Ltd Encapsulated glycolipid antigens for treatment of neoplastic diseases
EP4061802A4 (en) * 2019-12-23 2024-01-24 Agrospheres, Inc. COMPOSITIONS AND METHODS FOR IMPROVED ABSORPTION OF ACTIVE INGREDIENTS FOR ANIMAL HEALTH AND NUTRITION

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SG10201507969PA (en) * 2007-03-30 2015-10-29 Engeneic Molecular Delivery Pty Ltd Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells

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AU2008291833A1 (en) 2009-03-05
SI2865755T1 (sl) 2017-06-30
DK2865755T3 (en) 2017-05-15
CY1119031T1 (el) 2018-01-10
CA2933978C (en) 2018-08-21
SG10201507969PA (en) 2015-10-29
JP5167338B2 (ja) 2013-03-21
HK1209786A1 (en) 2016-04-08
WO2009027830A2 (en) 2009-03-05
PT2145002E (pt) 2015-04-29
CA2682704C (en) 2014-07-08
ES2534435T3 (es) 2015-04-22
EP2532746A2 (en) 2012-12-12
CN101715489A (zh) 2010-05-26
EP2145002A2 (en) 2010-01-20
PT2865755T (pt) 2017-05-26
JP2010523487A (ja) 2010-07-15
WO2009027830A3 (en) 2009-05-14
CN105854029A (zh) 2016-08-17
EP3564372A1 (en) 2019-11-06
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EP2865755B1 (en) 2017-02-01
EP2865755A2 (en) 2015-04-29
EP3205724B1 (en) 2019-05-08
SI2145002T1 (sl) 2015-05-29
SG10201804257RA (en) 2018-06-28
CN105854029B (zh) 2019-10-18
HK1138326A1 (en) 2010-08-20
DK2145002T3 (en) 2015-04-20
EP2865755A3 (en) 2015-05-06
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LT2865755T (lt) 2017-07-25
HRP20170662T1 (hr) 2017-07-14
EP2532746A3 (en) 2013-08-14
CN101715489B (zh) 2016-05-25
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NZ580487A (en) 2012-04-27
CA2682704A1 (en) 2009-03-05
PL2865755T3 (pl) 2017-08-31
CA2844647A1 (en) 2009-03-05
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CA2933978A1 (en) 2009-03-05

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