HRP20140280T1 - Uporaba 1-fenil-3-dimetilamino-propan spojeva u terapiji neuropatske boli - Google Patents

Uporaba 1-fenil-3-dimetilamino-propan spojeva u terapiji neuropatske boli Download PDF

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Publication number
HRP20140280T1
HRP20140280T1 HRP20140280AT HRP20140280T HRP20140280T1 HR P20140280 T1 HRP20140280 T1 HR P20140280T1 HR P20140280A T HRP20140280A T HR P20140280AT HR P20140280 T HRP20140280 T HR P20140280T HR P20140280 T1 HRP20140280 T1 HR P20140280T1
Authority
HR
Croatia
Prior art keywords
dimethylamino
therapy
phenyl
neuropathy pain
propane compounds
Prior art date
Application number
HRP20140280AT
Other languages
English (en)
Inventor
Thomas Christoph
Babette-Yvonne Kögel
Elmar Friderichs
Muriel Meen
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39345501&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20140280(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of HRP20140280T1 publication Critical patent/HRP20140280T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (2)

1. (1R,2R)-3-(3-Dimetilamino-1-etil-2-metilpropil)-fenol u prikazanom obliku ili u obliku fiziološki prihvatljive soli, za uporabu u liječenju dijabetske neuropatske boli ili dijabetske neuropatije administracijom od 0.01 do 5 mg/kg tjelesne mase.
2. (1R,2R)-3-(3-Dimetilamino-1-etil-2-metilpropil)-fenol za uporabu prema patentnom zahtjevu 1, pri čemu je dijabetska neuropatska bol ili dijabetska neuropatija periferalna.
HRP20140280AT 2007-03-12 2014-03-24 Uporaba 1-fenil-3-dimetilamino-propan spojeva u terapiji neuropatske boli HRP20140280T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007012165A DE102007012165A1 (de) 2007-03-12 2007-03-12 Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes
PCT/EP2008/001884 WO2008110323A1 (de) 2007-03-12 2008-03-10 Verwendung von 1-phenyl-3-dimethylamino-propanverbindungen zur therapie des neuropathieschmerzes

Publications (1)

Publication Number Publication Date
HRP20140280T1 true HRP20140280T1 (hr) 2014-04-25

Family

ID=39345501

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20140280AT HRP20140280T1 (hr) 2007-03-12 2014-03-24 Uporaba 1-fenil-3-dimetilamino-propan spojeva u terapiji neuropatske boli

Country Status (13)

Country Link
US (2) US20080269326A1 (hr)
EP (1) EP2117525B1 (hr)
JP (5) JP2010520907A (hr)
CA (1) CA2680771C (hr)
CY (1) CY1115455T1 (hr)
DE (1) DE102007012165A1 (hr)
DK (1) DK2117525T3 (hr)
ES (1) ES2452830T3 (hr)
HR (1) HRP20140280T1 (hr)
PL (1) PL2117525T3 (hr)
PT (1) PT2117525E (hr)
SI (1) SI2117525T1 (hr)
WO (1) WO2008110323A1 (hr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011157391A1 (en) 2010-06-15 2011-12-22 Grünenthal GmbH Pharmaceutical combination for the treatment of pain
KR102146233B1 (ko) * 2010-07-23 2020-08-21 그뤼넨탈 게엠베하 ３-(３-디메틸아미노-１-에틸-２-메틸-프로필)-페놀의 염 또는 공결정
WO2012051246A1 (en) 2010-10-12 2012-04-19 Ratiopharm Gmbh Tapentadol hydrobromide and crystalline forms thereof
RS56692B1 (sr) * 2011-03-04 2018-03-30 Gruenenthal Gmbh Polučvrsta vodena farmaceutska kompozicija koja sadrži tapentadol
HUE027514T2 (en) 2011-03-04 2016-10-28 Gruenenthal Gmbh Parenteral administration of tapentadol
PT2680832T (pt) 2011-03-04 2019-10-28 Gruenenthal Gmbh Formulação farmacêutica aquosa de tapentadol para administração oral
JP2019142972A (ja) * 2011-03-04 2019-08-29 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング タペンタドールの非経口的投与
US20120309840A1 (en) * 2011-04-05 2012-12-06 Gruenenthal Gmbh Treatment of Pain Associated with Trigeminal Neuralgia
PT2694049T (pt) 2011-04-05 2019-02-06 Gruenenthal Gmbh Tapentadol para prevenir a cronicidade da dor
RS60152B1 (sr) 2011-04-29 2020-05-29 Gruenenthal Gmbh Tapentadol za sprečavanje i lečenje depresije i anksioznosti
WO2013016840A1 (zh) 2011-07-29 2013-02-07 安徽省新星药物开发有限责任公司 用于合成他喷他多或其类似物的新中间体
LT2736501T (lt) 2011-07-29 2018-03-26 GrĆ¼nenthal GmbH 3-[(1s,2s)-3-(dimetilamino)-1-etil-2-metilpropil]fenolio intratekalinis arba epiduralinis skyrimas
CN103159633B (zh) * 2012-07-06 2015-08-12 江苏恩华药业股份有限公司 他喷他多的制备方法及用于制备他喷他多的化合物
EP2808319A1 (en) 2013-05-31 2014-12-03 Arevipharma GmbH 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex
PT3479823T (pt) 2015-03-27 2020-09-29 Gruenenthal Gmbh Formulação estável para administração parentérica de tapentadol
MX2019003257A (es) 2016-09-23 2019-06-10 Gruenenthal Gmbh Formulacion estable para la administracion parenteral de tapentadol.
EP3585370A1 (en) 2017-02-23 2020-01-01 Grünenthal GmbH Tapentadol as local anesthetic

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
SI1685829T1 (sl) * 2002-11-22 2008-08-31 Gruenenthal Gmbh Uporaba (1RS,3RS,6RS)-6-dimetilaminometil-1- (3-metoksi-fenil)-cikloheksan-1, 3-diola za zdravljenje vnetne bolečine
PT2012764E (pt) * 2006-04-28 2011-02-02 Gruenenthal Gmbh Combinação farmacêutica que compreende 3-(3-dimetilamino-1- etil-2-metilpropil)fenol e paracetamol

Also Published As

Publication number Publication date
PT2117525E (pt) 2014-02-14
CY1115455T1 (el) 2017-01-04
JP2018030886A (ja) 2018-03-01
JP6081337B2 (ja) 2017-02-15
EP2117525B1 (de) 2013-12-25
DE102007012165A1 (de) 2008-09-18
WO2008110323A1 (de) 2008-09-18
US20080269326A1 (en) 2008-10-30
US20100311842A1 (en) 2010-12-09
SI2117525T1 (sl) 2014-03-31
JP2016056188A (ja) 2016-04-21
CA2680771C (en) 2015-11-17
EP2117525A1 (de) 2009-11-18
PL2117525T3 (pl) 2014-05-30
US8536130B2 (en) 2013-09-17
CA2680771A1 (en) 2008-09-18
ES2452830T3 (es) 2014-04-02
JP6745959B2 (ja) 2020-08-26
DK2117525T3 (da) 2014-02-03
JP2013256540A (ja) 2013-12-26
JP2019196405A (ja) 2019-11-14
JP2010520907A (ja) 2010-06-17

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