HRP20120936T1 - Novo ojaäśano blister pakiranje - Google Patents

Novo ojaäśano blister pakiranje Download PDF

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Publication number
HRP20120936T1
HRP20120936T1 HRP20120936AT HRP20120936T HRP20120936T1 HR P20120936 T1 HRP20120936 T1 HR P20120936T1 HR P20120936A T HRP20120936A T HR P20120936AT HR P20120936 T HRP20120936 T HR P20120936T HR P20120936 T1 HRP20120936 T1 HR P20120936T1
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HR
Croatia
Prior art keywords
layer
blister packaging
thermoformed
packaging according
blister
Prior art date
Application number
HRP20120936AT
Other languages
English (en)
Inventor
Massimiliano Rossi
Original Assignee
E-Pharma Trento S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E-Pharma Trento S.P.A. filed Critical E-Pharma Trento S.P.A.
Publication of HRP20120936T1 publication Critical patent/HRP20120936T1/hr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C51/00—Shaping by thermoforming, i.e. shaping sheets or sheet like preforms after heating, e.g. shaping sheets in matched moulds or by deep-drawing; Apparatus therefor
    • B29C51/08—Deep drawing or matched-mould forming, i.e. using mechanical means only
    • B29C51/082—Deep drawing or matched-mould forming, i.e. using mechanical means only by shaping between complementary mould parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7162—Boxes, cartons, cases
    • B29L2031/7164—Blister packages
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/36—One sheet or blank being recessed and the other formed or relatively stiff flat sheet material, e.g. blister packages
    • B65D2575/361—Details
    • B65D2575/362—Details with special means for gaining access to the contents
    • B65D2575/366—Details with special means for gaining access to the contents through a preformed opening in the recessed sheet, e.g. the opening being defined by weakened lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Composite Materials (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)

Claims (30)

1. Blister pakiranje koje se sastoji od najmanje prvog termoformiranog sloja (7), gornjeg sloja (6) koji zatvara i pokriva gornju površinu navedenog prvog termoformiranog sloja (7) i oblikovanog sloja (8) koji zatvara i pokriva donju površinu navedenog blister pakiranja, naznačeno time što navedeni prvi termoformirani sloj sadrži sustav ojačavanja koji sadrži uklonjivu kapsulu (10).
2. Blister pakiranje prema 1. zahtjevu, naznačeno time da navedena uklonjiva kapsula (10) ima najmanje jednu neprekinutu površinu (3) s navedenim prvim termoformiranim slojem (7) i najmanje jednu prekinutu površinu (5) s navedenim prvim termoformiranim slojem (7).
3. Blister pakiranje prema 2. zahtjevu, naznačeno time da navedena uklonjiva kapsula (10) ima najmanje dvije neprekinute površine (3, 4) s navedenim prvim termoformiranim slojem (7) i najmanje dvije prekinute površine (5, 5a) iz navedenog prvog termoformiranog slojem (7).
4. Blister pakiranje prema 3. zahtjevu, naznačeno time da su te najmanje dvije neprekinute površine (3 4) različitih dimenzija.
5. Blister pakiranje prema 4. zahtjevu, naznačeno time da te najmanje dvije neprekinute površine (3, 4) imaju takve dimenzije da im je omjer između 5:1 i 25:1.
6. Blister pakiranje prema bilo kojem od prethodnih zahtjeva, naznačeno time da je navedeni prvi termoformirani sloj (7) debeo između 0,2 mm i 0.6 mm.
7. Blister pakiranje prema bilo kojem od prethodnih zahtjeva, naznačeno time da navedem prvi termoformirani sloj (7) sadrži najmanje jedan polimer odabran iz skupine koja se sastoji od: polivinil klorida, poliviniliden klorida, poliakrilonitrila, poliklorotrifluoretilena, polietilena, polietilen tereftalata, polietilen naftalata, polipropilena, polistirena, poliestera, poliamida ili njihovih kopolimera.
8. Blister pakiranje prema 1. zahtjevu, naznačeno time da navedeni gornji sloj (6) sadrži najmanje jedan aluminijski sloj (6A).
9. Blister pakiranje prema 8. zahtjevu, naznačeno time da navedeni aluminijski sloj (6A) debeo između 5 i 50 µm.
10. Blister pakiranje prema 8., naznačeno time da navedeni gornji sloj (6) sadrži najmanje još dva sloja (6B, 6C) koji se nalaze na suprotnim stranama navedenog aluminijskog sloja (6A).
11. Blister pakiranje prema 10. zahtjevu, naznačeno time da svaki od navedena dva sloja (6B, 6C), a koji su isti ili različiti, sadrži polimer odabran iz skupine koja se sastoji od: polivinil klorida, poliviniliden klorida, polipropilena, polietilen tereftalata, poliakrilata poliakrilonitrila, cikličkih olefina, polistirena, poliestera, poliamida, etilen vinil alkohola, polivinil alkohola ili njihovih kopolimera.
12. Blister pakiranje prema 10, zahtjevu naznačeno time da navedeni sloj (6B) debeo između 5 i 50 µm.
13. Blister pakiranje prema 10. zahtjevu naznačeno time da navedeni sloj (6C) debeo između 10 i 90 µm.
14. Blister pakiranje prema 1. zahtjevu, naznačeno time da navedeni oblikovani sloj (8) sadrži najmanje jedan sloj polimerskog materijala (8A).
15. Blister pakiranje prema 14. zahtjevu, naznačeno time da navedeni polimerski materijal (8a) debeo između 5 i 50 µm.
16. Blister pakiranje prema 14. zahtjevu, naznačeno time da navedeni polimerski materijal (8A) sadrži polimer odabran iz skupine koja se sastoji od: polivinil klorida, poliviniliden klorida, polipropilena, polietilen tereftalata, poliakrilata, poliakrilonitrila, cikličkih olefina, polistirena, poliestera, poliamida, etilen vinil alkohola, polivinil alkohola ili njihovih kopolimera.
17. Blister pakiranje prema 14. zahtjevu, naznačeno time da navedeni oblikovani sloj (8) sadrži najmanje jedan drugi sloj (8B) koji se nalazi ispod navedenog sloja (8A).
18. Blister pakiranje prema 17. zahtjevu, naznačeno time da navedeni drugi sloj (8B) sadrži aluminijski sloj.
19. Blister pakiranje prema 18. zahtjevu, naznačeno time da navedeni aluminijski sloj debeo između 5 i 80 µm.
20. Blister pakiranje prema 17. zahtjevu, naznačeno time da navedeni drugi sloj (8B) pokriven slojem boje (8C).
21. Proces proizvodnje ojačanog blister pakiranja, naznačeno time da se sastoji od sljedećih faza: (I) isporučivanje i odmotavanje namotaja (19) polimerskog lima (20) kako bi se formirao termoformirani sloj (7), (II) grijanje tog lima (20), (III) izrada tog termoformiranog sloja (7) pomoću termoformiranja najmanje jedne kapsule u navedenom limu (20), (IV) bušenje navedene najmanje jedne kapsule na gornjoj bazi kako bi se formirala najmanje jedna uklonjiva kapsula (10) u navedenom termoformiranom sloju (7), (VII) isporučivanje i odmotavanje namotaja (24) kako bi se formirao gornji sloj (6), (VIII) zavarivanje navedenog gornjeg sloja (6) kako bi se pokrila i zatvorila gornja površina navedenog termoformiranog sloja (7), (IX) isporučivanje i odmotavanje namotaja (26) lima (27) kako bi se formirao oblikovani sloj (8), (X) formiranje navedenog oblikovanog sloja (8) na način da se formira najmanje jedan blister (2) u navedeno limu (27) i (XI) zavarivanje navedenog oblikovanog sloja (8) kako bi se pokrila i zatvorila donja površina navedenog prvog termoformiranog sloja (7).
22. Proces prema 21. zahtjevu, naznačeno time da faza bušenja (IV) omogućuje održavanje najmanje jedne neprekinute površine (3) s navedenim termoformiranim slojem (7) i najmanje jedne prekinute površine (5) iz navedenog termoformiranog sloja (7).
23. Proces prema 22. zahtjevu, naznačeno time da faza bušenja (IV) omogućuje održavanje najmanje dviju neprekinutih površina (3, 4) s navedenim termoformiranim slojem (7) i najmanje dviju prekinutih površina (5, 5A) iz navedenog termoformiranog sloja (7).
24. Proces prema 23. zahtjevu, naznačeno time da su navedene dvije neprekinute površine (3, 4) različitih dimenzija.
25. Proces prema 24. zahtjevu, naznačeno time da te najmanje dvije neprekinute površine (3, 4) imaju takve dimenzije da im je omjer između 5:1 i 25:1.
26. Proces prema bilo kojem od prethodnih zahtjeva, naznačeno time da sadrži faze (V) isporučivanja farmaceutskih oblika (9) koji će biti uključeni u blister pakiranje (1) i (VI) postavljanja navedenih farmaceutskih oblika (9) u uklonjive kapsule (10).
27. Proces prema 26. zahtjevu, naznačeno time da sadrži faze provjeravanja da li se navedeni farmaceutski oblici (9) nalaze u uklonjivim kapsulama (10) te otprašivanja navedenih farmaceutskih oblika (9).
28. Proces prema 21. zahtjevu, naznačeno time da se navedena faza (VIII) zavarivanja gornjeg sloja (6) provodi mehanički na cca. 180°C te se nanosi tlak od cca. 15 kg/cm2.
29. Proces prema 21. zahtjevu, naznačeno time da se navedena faza (X) formiranja navedenog oblikovanog sloja (8) obavlja hladno pomoću bušaća presvučenih teflonom.
30. Proces prema 21. zahtjevu, naznačeno time da se navedena faza (XI) zavarivanja navedenog oblikovanog sloja (8) provodi na cca. 180°C te se nanosi tlak od cca. 20 kg/cm2.
HRP20120936AT 2010-02-10 2012-11-19 Novo ojaäśano blister pakiranje HRP20120936T1 (hr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10425027A EP2353573B1 (en) 2010-02-10 2010-02-10 New strengthened blister pack

Publications (1)

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HRP20120936T1 true HRP20120936T1 (hr) 2012-12-31

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HRP20120936AT HRP20120936T1 (hr) 2010-02-10 2012-11-19 Novo ojaäśano blister pakiranje

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US (1) US9850051B2 (hr)
EP (1) EP2353573B1 (hr)
CA (1) CA2730464C (hr)
CY (1) CY1117300T1 (hr)
ES (1) ES2391885T3 (hr)
HR (1) HRP20120936T1 (hr)
PL (1) PL2353573T3 (hr)
PT (1) PT2353573E (hr)
SI (1) SI2353573T1 (hr)
SM (1) SMT201200050B (hr)

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US9150119B2 (en) 2013-03-15 2015-10-06 Aesynt Incorporated Apparatuses, systems, and methods for anticipating and delivering medications from a central pharmacy to a patient using a track based transport system
US20140108027A1 (en) 2012-10-12 2014-04-17 Mckesson Automation Inc. Apparatuses, systems, and methods for delivering medications from a central pharmacy to a patient in a healthcare facility
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EP2996678A1 (en) * 2013-05-16 2016-03-23 Sandoz AG Tablet with increased drug load of odanacatib
EP2860120A1 (de) * 2013-10-10 2015-04-15 Uhlmann Pac-Systeme GmbH & Co. KG Verpackung für Tabletten und Vorrichtung zum Herstellen der Verpackung
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CN106275620B (zh) * 2016-10-11 2019-06-07 宋占涛 无菌包装机
CN106275576B (zh) * 2016-10-11 2019-06-07 宋占涛 无菌包装机用热封吹气装置
CN107600510B (zh) * 2017-10-18 2024-05-31 上海合全医药有限公司 一种避免氧化和吸湿的软质真空包装装置及方法

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Also Published As

Publication number Publication date
EP2353573A1 (en) 2011-08-10
CA2730464C (en) 2018-01-02
EP2353573B1 (en) 2012-08-22
SMT201200050B (it) 2013-01-14
PT2353573E (pt) 2012-10-11
US9850051B2 (en) 2017-12-26
PL2353573T3 (pl) 2013-01-31
CA2730464A1 (en) 2011-08-10
US20110192759A1 (en) 2011-08-11
CY1117300T1 (el) 2017-04-26
ES2391885T3 (es) 2012-11-30
SI2353573T1 (sl) 2012-12-31

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