HRP20110127T1 - Aksomadol za liječenje kod artritisa - Google Patents
Aksomadol za liječenje kod artritisa Download PDFInfo
- Publication number
- HRP20110127T1 HRP20110127T1 HR20110127T HRP20110127T HRP20110127T1 HR P20110127 T1 HRP20110127 T1 HR P20110127T1 HR 20110127 T HR20110127 T HR 20110127T HR P20110127 T HRP20110127 T HR P20110127T HR P20110127 T1 HRP20110127 T1 HR P20110127T1
- Authority
- HR
- Croatia
- Prior art keywords
- pain
- use according
- drug
- axomadol
- arthrosis
- Prior art date
Links
- 208000002193 Pain Diseases 0.000 title claims abstract 17
- LQJLLAOISDVBJM-FMKPAKJESA-N axomadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CC[C@@H](O)C2)CN(C)C)=C1 LQJLLAOISDVBJM-FMKPAKJESA-N 0.000 title claims abstract 4
- 229950005531 axomadol Drugs 0.000 title claims abstract 4
- 206010003246 arthritis Diseases 0.000 title 1
- 201000008482 osteoarthritis Diseases 0.000 claims abstract 5
- 239000003814 drug Substances 0.000 claims 6
- 229940079593 drug Drugs 0.000 claims 4
- 230000002269 spontaneous effect Effects 0.000 claims 2
- 206010006002 Bone pain Diseases 0.000 claims 1
- 208000007353 Hip Osteoarthritis Diseases 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- 208000000112 Myalgia Diseases 0.000 claims 1
- 206010033425 Pain in extremity Diseases 0.000 claims 1
- 208000013465 muscle pain Diseases 0.000 claims 1
- 230000000284 resting effect Effects 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 201000005671 spondyloarthropathy Diseases 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007022790A DE102007022790A1 (de) | 2007-05-11 | 2007-05-11 | Axomadol zur Schmerzbehandlung bei Arthrose |
| PCT/EP2008/003755 WO2008138558A1 (de) | 2007-05-11 | 2008-05-09 | Axomadol zur schmerzbehandlung bei arthrose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20110127T1 true HRP20110127T1 (hr) | 2011-03-31 |
Family
ID=39672675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20110127T HRP20110127T1 (hr) | 2007-05-11 | 2011-02-23 | Aksomadol za liječenje kod artritisa |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US20080306161A1 (ko) |
| EP (1) | EP2155179B1 (ko) |
| JP (1) | JP2010526786A (ko) |
| KR (1) | KR20100017781A (ko) |
| CN (1) | CN101742993A (ko) |
| AT (1) | ATE489947T1 (ko) |
| AU (1) | AU2008250621A1 (ko) |
| CA (1) | CA2685379A1 (ko) |
| CY (1) | CY1111328T1 (ko) |
| DE (2) | DE102007022790A1 (ko) |
| DK (1) | DK2155179T3 (ko) |
| ES (1) | ES2357355T3 (ko) |
| HK (1) | HK1141436A1 (ko) |
| HR (1) | HRP20110127T1 (ko) |
| IL (1) | IL202001A0 (ko) |
| MX (1) | MX2009012096A (ko) |
| PL (1) | PL2155179T3 (ko) |
| PT (1) | PT2155179E (ko) |
| RU (1) | RU2009145804A (ko) |
| SI (1) | SI2155179T1 (ko) |
| WO (1) | WO2008138558A1 (ko) |
| ZA (1) | ZA200907646B (ko) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011008298A2 (en) * | 2009-07-16 | 2011-01-20 | Nectid, Inc. | Novel axomadol dosage forms |
| WO2011023392A1 (en) | 2009-08-28 | 2011-03-03 | Grünenthal GmbH | Pharmaceutical combination comprising 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol or 6-dimethylaminomethyl-1-(3-hydroxy-phenyl)-cyclohexane-1,3-diol and an antiepileptic |
| WO2011029614A1 (en) | 2009-09-14 | 2011-03-17 | Grünenthal GmbH | Crystalline modifications of 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol |
| US20120022294A1 (en) * | 2010-06-30 | 2012-01-26 | Gruenenthal Gmbh | Axomadol or a Metabolite Thereof for Use in the Treatment of Irritable Bowel Syndrome |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19525137C2 (de) | 1995-07-11 | 2003-02-27 | Gruenenthal Gmbh | 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe |
| DE10004926A1 (de) * | 2000-02-04 | 2001-08-09 | Gruenenthal Gmbh | Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten |
| DE10059413A1 (de) * | 2000-11-30 | 2002-06-20 | Gruenenthal Gmbh | Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz |
| US20050176790A1 (en) * | 2001-02-28 | 2005-08-11 | Johannes Bartholomaus | Pharmaceutical salts |
| DE10109763A1 (de) | 2001-02-28 | 2002-09-05 | Gruenenthal Gmbh | Pharmazeutische Salze |
| DE10146275A1 (de) * | 2001-09-18 | 2003-04-24 | Gruenenthal Gmbh | Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz |
| SI1685829T1 (sl) * | 2002-11-22 | 2008-08-31 | Gruenenthal Gmbh | Uporaba (1RS,3RS,6RS)-6-dimetilaminometil-1- (3-metoksi-fenil)-cikloheksan-1, 3-diola za zdravljenje vnetne bolečine |
| DE10333835A1 (de) * | 2003-07-24 | 2005-03-10 | Gruenenthal Gmbh | 6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol enthaltendes Arzneimittel mit verzögerter Wirkstofffreisetzung |
| PL1765303T5 (pl) * | 2004-07-01 | 2023-05-22 | Grünenthal GmbH | Tabletka doustna zabezpieczona przed nadużywaniem |
| CA2598579A1 (en) * | 2005-02-25 | 2006-08-31 | Gruenenthal Gmbh | Crystalline forms of (1rs,3rs,6rs)-6-dimethvlaminomethvl-1-(3-methoxv- phenyl)cyclohexane-1 ,3-diol hydrochloride |
| DE102005009217A1 (de) * | 2005-02-25 | 2006-08-31 | Grünenthal GmbH | Phosphatsalze der 6-Dimethylaminomethyl-1-(3-methoxyphenyl)-1,3-dihydroxy-cyclohexanverbindungen |
-
2007
- 2007-05-11 DE DE102007022790A patent/DE102007022790A1/de not_active Withdrawn
-
2008
- 2008-05-09 RU RU2009145804/15A patent/RU2009145804A/ru not_active Application Discontinuation
- 2008-05-09 PT PT08758440T patent/PT2155179E/pt unknown
- 2008-05-09 DK DK08758440.5T patent/DK2155179T3/da active
- 2008-05-09 KR KR1020097025938A patent/KR20100017781A/ko not_active Application Discontinuation
- 2008-05-09 CN CN200880015678A patent/CN101742993A/zh active Pending
- 2008-05-09 DE DE502008001951T patent/DE502008001951D1/de active Active
- 2008-05-09 JP JP2010506858A patent/JP2010526786A/ja active Pending
- 2008-05-09 US US12/118,231 patent/US20080306161A1/en not_active Abandoned
- 2008-05-09 WO PCT/EP2008/003755 patent/WO2008138558A1/de active Application Filing
- 2008-05-09 AT AT08758440T patent/ATE489947T1/de active
- 2008-05-09 SI SI200830139T patent/SI2155179T1/sl unknown
- 2008-05-09 AU AU2008250621A patent/AU2008250621A1/en not_active Abandoned
- 2008-05-09 PL PL08758440T patent/PL2155179T3/pl unknown
- 2008-05-09 ES ES08758440T patent/ES2357355T3/es active Active
- 2008-05-09 EP EP08758440A patent/EP2155179B1/de not_active Not-in-force
- 2008-05-09 MX MX2009012096A patent/MX2009012096A/es active IP Right Grant
- 2008-05-09 CA CA002685379A patent/CA2685379A1/en not_active Abandoned
-
2009
- 2009-10-30 ZA ZA200907646A patent/ZA200907646B/xx unknown
- 2009-11-09 IL IL202001A patent/IL202001A0/en unknown
-
2010
- 2010-08-12 HK HK10107704.0A patent/HK1141436A1/xx not_active IP Right Cessation
- 2010-09-10 US US12/879,562 patent/US20100331424A1/en not_active Abandoned
-
2011
- 2011-02-16 CY CY20111100191T patent/CY1111328T1/el unknown
- 2011-02-23 HR HR20110127T patent/HRP20110127T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200907646B (en) | 2010-07-28 |
| EP2155179A1 (de) | 2010-02-24 |
| JP2010526786A (ja) | 2010-08-05 |
| ES2357355T3 (es) | 2011-04-25 |
| CY1111328T1 (el) | 2015-08-05 |
| DE102007022790A1 (de) | 2008-11-20 |
| US20080306161A1 (en) | 2008-12-11 |
| CN101742993A (zh) | 2010-06-16 |
| MX2009012096A (es) | 2009-11-23 |
| KR20100017781A (ko) | 2010-02-16 |
| DE502008001951D1 (de) | 2011-01-13 |
| RU2009145804A (ru) | 2011-06-20 |
| HK1141436A1 (en) | 2010-11-12 |
| ATE489947T1 (de) | 2010-12-15 |
| PT2155179E (pt) | 2011-03-07 |
| WO2008138558A1 (de) | 2008-11-20 |
| EP2155179B1 (de) | 2010-12-01 |
| US20100331424A1 (en) | 2010-12-30 |
| CA2685379A1 (en) | 2008-11-20 |
| SI2155179T1 (sl) | 2011-03-31 |
| IL202001A0 (en) | 2010-06-16 |
| DK2155179T3 (da) | 2011-03-07 |
| AU2008250621A1 (en) | 2008-11-20 |
| PL2155179T3 (pl) | 2011-05-31 |
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