HRP20070498T3 - Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents
Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- HRP20070498T3 HRP20070498T3 HR20070498T HRP20070498T HRP20070498T3 HR P20070498 T3 HRP20070498 T3 HR P20070498T3 HR 20070498 T HR20070498 T HR 20070498T HR P20070498 T HRP20070498 T HR P20070498T HR P20070498 T3 HRP20070498 T3 HR P20070498T3
- Authority
- HR
- Croatia
- Prior art keywords
- straight
- optionally substituted
- branched
- halogen
- group
- Prior art date
Links
- PWOUAMWQYHOLIB-UHFFFAOYSA-N 1-(2,3-dihydro-1h-inden-1-yl)piperazine Chemical class C1CC2=CC=CC=C2C1N1CCNCC1 PWOUAMWQYHOLIB-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000001072 heteroaryl group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 230000003287 optical effect Effects 0.000 abstract 2
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000004385 trihaloalkyl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 235000010290 biphenyl Nutrition 0.000 abstract 1
- 239000004305 biphenyl Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Quinoline Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0503071A FR2883876B1 (fr) | 2005-03-30 | 2005-03-30 | Derives d'indanyl-piperazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20070498T3 true HRP20070498T3 (en) | 2007-12-31 |
Family
ID=35079249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20070498T HRP20070498T3 (en) | 2005-03-30 | 2007-10-25 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them |
Country Status (37)
Country | Link |
---|---|
US (1) | US7442692B2 (xx) |
EP (1) | EP1707564B1 (xx) |
JP (1) | JP4503549B2 (xx) |
KR (1) | KR100766664B1 (xx) |
CN (1) | CN100467458C (xx) |
AP (1) | AP2007004169A0 (xx) |
AR (1) | AR054747A1 (xx) |
AT (1) | ATE372992T1 (xx) |
AU (1) | AU2006201326A1 (xx) |
BR (1) | BRPI0602132A (xx) |
CA (1) | CA2541066C (xx) |
CR (1) | CR9391A (xx) |
CY (1) | CY1107028T1 (xx) |
DE (1) | DE602006000102T2 (xx) |
DK (1) | DK1707564T3 (xx) |
EA (1) | EA010051B1 (xx) |
ES (1) | ES2293630T3 (xx) |
FR (1) | FR2883876B1 (xx) |
GE (1) | GEP20084544B (xx) |
GT (1) | GT200700084A (xx) |
HK (1) | HK1096386A1 (xx) |
HR (1) | HRP20070498T3 (xx) |
IL (1) | IL186062A (xx) |
MA (1) | MA28211A1 (xx) |
MX (1) | MXPA06003552A (xx) |
MY (1) | MY140325A (xx) |
NO (1) | NO20061334L (xx) |
NZ (1) | NZ546186A (xx) |
PL (1) | PL1707564T3 (xx) |
PT (1) | PT1707564E (xx) |
RS (1) | RS50527B (xx) |
SG (1) | SG126113A1 (xx) |
SI (1) | SI1707564T1 (xx) |
TN (1) | TNSN07357A1 (xx) |
UA (1) | UA87989C2 (xx) |
WO (1) | WO2006103342A2 (xx) |
ZA (1) | ZA200602631B (xx) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8071778B2 (en) * | 2006-07-27 | 2011-12-06 | Bristol-Myers Squibb Company | Substituted heterocyclic ethers and their use in CNS disorders |
US20090018163A1 (en) * | 2007-07-11 | 2009-01-15 | Bristol-Myers Squibb Company | Substituted Heterocyclic Ethers and Their Use in CNS Disorders |
US8026257B2 (en) * | 2007-07-11 | 2011-09-27 | Bristol-Myers Squibb Company | Substituted heterocyclic ethers and their use in CNS disorders |
US7632861B2 (en) * | 2007-11-13 | 2009-12-15 | Bristol-Myers Squibb Company | Substituted heterocyclic ethers and their use in CNS disorders |
EP3628666A1 (en) | 2018-09-25 | 2020-04-01 | Antabio SAS | Indane derivatives for use in the treatment of bacterial infection |
EP3628672A1 (en) | 2018-09-25 | 2020-04-01 | Antabio SAS | Indane derivatives for use in the treatment of bacterial infection |
EP3856730A1 (en) | 2018-09-25 | 2021-08-04 | Antabio SAS | Indane derivatives for use in the treatment of bacterial infection |
WO2020064175A1 (en) | 2018-09-25 | 2020-04-02 | Antabio Sas | Indane derivatives for use in the treatment of bacterial infection |
WO2021191240A1 (en) | 2020-03-24 | 2021-09-30 | Antabio Sas | Combination therapy |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1335591C (en) * | 1988-05-23 | 1995-05-16 | James Arthur Nixon | Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes |
DK286990D0 (da) * | 1990-12-04 | 1990-12-04 | Lundbeck & Co As H | Indanderivater |
CA2175395A1 (en) * | 1995-06-02 | 1996-12-03 | Ronald J. Mattson | Melatonergic indanyl piperazines or homopiperazines |
FR2769312B1 (fr) * | 1997-10-03 | 1999-12-03 | Adir | Nouveaux composes de l'indanol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2827284B1 (fr) * | 2001-07-16 | 2003-10-31 | Servier Lab | Nouveaux derives de n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AU2003284165B2 (en) * | 2002-10-30 | 2008-12-11 | Merck Sharp & Dohme Corp. | Piperidinyl-alpha-aminoamide modulators of chemokine receptor activity |
-
2005
- 2005-03-30 FR FR0503071A patent/FR2883876B1/fr not_active Expired - Fee Related
-
2006
- 2006-03-16 MA MA28880A patent/MA28211A1/fr unknown
- 2006-03-23 NO NO20061334A patent/NO20061334L/no not_active Application Discontinuation
- 2006-03-28 SG SG200602026A patent/SG126113A1/en unknown
- 2006-03-28 NZ NZ546186A patent/NZ546186A/en not_active IP Right Cessation
- 2006-03-28 GE GEAP20069324A patent/GEP20084544B/en unknown
- 2006-03-29 EP EP06290494A patent/EP1707564B1/fr active Active
- 2006-03-29 ES ES06290494T patent/ES2293630T3/es active Active
- 2006-03-29 US US11/391,916 patent/US7442692B2/en not_active Expired - Fee Related
- 2006-03-29 PT PT06290494T patent/PT1707564E/pt unknown
- 2006-03-29 UA UAA200603429A patent/UA87989C2/ru unknown
- 2006-03-29 AP AP2007004169A patent/AP2007004169A0/xx unknown
- 2006-03-29 WO PCT/FR2006/000673 patent/WO2006103342A2/fr not_active Application Discontinuation
- 2006-03-29 SI SI200630005T patent/SI1707564T1/sl unknown
- 2006-03-29 RS RSP-2007/0478A patent/RS50527B/sr unknown
- 2006-03-29 DE DE602006000102T patent/DE602006000102T2/de active Active
- 2006-03-29 EA EA200600487A patent/EA010051B1/ru not_active IP Right Cessation
- 2006-03-29 AT AT06290494T patent/ATE372992T1/de active
- 2006-03-29 MY MYPI20061369A patent/MY140325A/en unknown
- 2006-03-29 PL PL06290494T patent/PL1707564T3/pl unknown
- 2006-03-29 DK DK06290494T patent/DK1707564T3/da active
- 2006-03-30 JP JP2006093025A patent/JP4503549B2/ja not_active Expired - Fee Related
- 2006-03-30 ZA ZA200602631A patent/ZA200602631B/xx unknown
- 2006-03-30 MX MXPA06003552A patent/MXPA06003552A/es active IP Right Grant
- 2006-03-30 CN CNB2006100669637A patent/CN100467458C/zh not_active Expired - Fee Related
- 2006-03-30 CA CA2541066A patent/CA2541066C/fr not_active Expired - Fee Related
- 2006-03-30 BR BRPI0602132-8A patent/BRPI0602132A/pt not_active IP Right Cessation
- 2006-03-30 KR KR1020060029085A patent/KR100766664B1/ko not_active IP Right Cessation
- 2006-03-30 AU AU2006201326A patent/AU2006201326A1/en not_active Abandoned
- 2006-03-30 AR ARP060101238A patent/AR054747A1/es not_active Application Discontinuation
-
2007
- 2007-02-01 HK HK07101184.7A patent/HK1096386A1/xx not_active IP Right Cessation
- 2007-09-18 TN TNP2007000357A patent/TNSN07357A1/en unknown
- 2007-09-19 IL IL186062A patent/IL186062A/en not_active IP Right Cessation
- 2007-09-24 CR CR9391A patent/CR9391A/es not_active Application Discontinuation
- 2007-09-28 GT GT200700084A patent/GT200700084A/es unknown
- 2007-10-25 HR HR20070498T patent/HRP20070498T3/xx unknown
- 2007-11-28 CY CY20071101540T patent/CY1107028T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HRP20070498T3 (en) | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | |
MEP10709A (en) | 2-ARYL-6-PHENYLIMIDAZO[1,2-alpha]PYRIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | |
BRPI0415374B8 (pt) | uso de um composto, composto, processo para a preparação do mesmo, composição farmacêutica, processo para a preparação da mesma, e, produto | |
RS51888B (en) | N- (PHENYL (PIPERIDIN-2-IL) METHYL) BENZAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | |
RU2012123154A (ru) | Способы лечения синдрома фибромиалгии | |
EA200870321A1 (ru) | Способ получения 4-оксохинолинового соединения | |
DK1961734T3 (da) | Aminforbindelse og anvendelse deraf til medicinske formål | |
RS52001B (en) | NEW DIAZENIUM DIIOLATE DERIVATIVES, PROCEDURE OF THEIR PRODUCTION AND THE PHARMACEUTICAL MIXTURES CONTAINING THEM | |
HRP20080097T3 (en) | Piperazine derivatives and their use as serotonin reuptake inhibitors or as neurokinin antagonists | |
RS52046B (en) | COMBINATION OF BIS-THIAZOLIUM SALT OR ITS PRECURSOR AND ARTEMISININ OR ITS DERIVATIVE TO ACUTE ACUTE MALARIA | |
EA201000666A1 (ru) | Производные 5-замещенных индол-3-карбоновой кислоты, обладающие противовирусной активностью, способ их получения и применение | |
GB0617867D0 (en) | Chemical compounds | |
SE1069132T3 (sv) | Bicykliska derivate av amino-pyrazinoner, foerfarande foer framstaellning och farmaceutiska kompositioner innehallande dem | |
RS50547B (sr) | Derivati 4-okso-4,6,7,8-tetrahidropirolo-1,2-a pirazin-6-karboksamida, postupak njihove izrade i farmaceutske smeše koje ih sadrže | |
HRP20080536T5 (en) | Polysubstituted 1,1-pyridinyloxycyclopropanamine derivatives, process for their preparation and pharmaceutical compositions containing them | |
HRP20080129T3 (en) | Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders | |
RS52835B (en) | DERIVATIVES OF DIHIDROBENZOXATIAZEPINE, THE PROCEDURE OF THEIR PRODUCTION AND THE PHARMACEUTICAL MIXTURES CONTAINING THEM, AND THEIR USE AS AN AMPA RECEPTOR MODULATORS | |
HRP20090090T3 (en) | Novel polysubstituted 1,1-pyridinylaminocyclopropanamine derivatives, processes for their preparation and pharmaceutical composition containing them | |
FR2903698B1 (fr) | Nouveaux derives de 5-thioxylopyranose. | |
HRP20070379A2 (en) | Amfifile oxalamide gelators for organic solvents, water and commercial carbohydrate fuels gelation | |
RS52698B (en) | NEW AZABICYCL [3.2.0] HEPT-3-ILA DERIVATIVES, A PROCEDURE FOR THEIR PRODUCTION AND THE PHARMACEUTICAL MIXTURES CONTAINING THEM | |
AR036680A1 (es) | Procedimiento para preparar derivados de heterocicloalquilsulfonilpirazol y compuestos utiles en su preparacion | |
NO20022891L (no) | Nye cykliske <alfa>-amino-<gamma>-hydroksyamidforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetningerinneholdende dem | |
TH101058B (th) | อนุพันธ์เบนซิมิแดโซล |