HRP20020704B1 - Monoclonal antibodies to the human ldl receptor, their production and use - Google Patents

Monoclonal antibodies to the human ldl receptor, their production and use

Info

Publication number
HRP20020704B1
HRP20020704B1 HR20020704A HRP20020704A HRP20020704B1 HR P20020704 B1 HRP20020704 B1 HR P20020704B1 HR 20020704 A HR20020704 A HR 20020704A HR P20020704 A HRP20020704 A HR P20020704A HR P20020704 B1 HRP20020704 B1 HR P20020704B1
Authority
HR
Croatia
Prior art keywords
ldl receptor
antibody
human
production
monoclonal antibodies
Prior art date
Application number
HR20020704A
Other languages
English (en)
Croatian (hr)
Inventor
Yonah Nachum
Suissa Dany
Belzer Ilana
Antoneti Francesco
Smolarsky Moshe
Dreano Michel
Original Assignee
Laboratoires Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26323933&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20020704(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from IL13502500A external-priority patent/IL135025A0/xx
Application filed by Laboratoires Serono Sa filed Critical Laboratoires Serono Sa
Publication of HRP20020704A2 publication Critical patent/HRP20020704A2/hr
Publication of HRP20020704B1 publication Critical patent/HRP20020704B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/82Hepatitis associated antigens and antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HR20020704A 2000-03-13 2002-08-28 Monoclonal antibodies to the human ldl receptor, their production and use HRP20020704B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL13502500A IL135025A0 (en) 2000-03-13 2000-03-13 Monoclonal antibodies to the human ldl receptor, their production and use
IL13921700A IL139217A0 (en) 2000-03-13 2000-10-23 Monoclonal antibodies to the human ldl receptor, their production and use
PCT/IL2001/000216 WO2001068710A1 (en) 2000-03-13 2001-03-08 Monoclonal antibodies to the human ldl receptor, their production and use

Publications (2)

Publication Number Publication Date
HRP20020704A2 HRP20020704A2 (en) 2004-12-31
HRP20020704B1 true HRP20020704B1 (en) 2011-01-31

Family

ID=26323933

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020704A HRP20020704B1 (en) 2000-03-13 2002-08-28 Monoclonal antibodies to the human ldl receptor, their production and use

Country Status (33)

Country Link
US (1) US6849720B2 (ja)
EP (1) EP1263790B1 (ja)
JP (1) JP4768193B2 (ja)
KR (1) KR100882081B1 (ja)
CN (1) CN1418225B (ja)
AR (1) AR028518A1 (ja)
AT (1) ATE362490T1 (ja)
AU (2) AU2001241002B8 (ja)
BG (1) BG65762B1 (ja)
BR (1) BR0109164A (ja)
CA (1) CA2402593C (ja)
CY (1) CY1108020T1 (ja)
CZ (1) CZ20023098A3 (ja)
DE (1) DE60128452T2 (ja)
DK (1) DK1263790T3 (ja)
EA (1) EA007494B1 (ja)
EE (1) EE200200517A (ja)
ES (1) ES2282238T3 (ja)
HK (1) HK1055750A1 (ja)
HR (1) HRP20020704B1 (ja)
HU (1) HU226194B1 (ja)
IL (2) IL139217A0 (ja)
MX (1) MXPA02009091A (ja)
NO (1) NO330904B1 (ja)
NZ (1) NZ520944A (ja)
PL (1) PL206041B1 (ja)
PT (1) PT1263790E (ja)
RS (1) RS51406B (ja)
SI (1) SI1263790T1 (ja)
SK (1) SK287348B6 (ja)
UA (1) UA78489C2 (ja)
WO (1) WO2001068710A1 (ja)
ZA (1) ZA200206654B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0114629D0 (en) * 2001-06-15 2001-08-08 Pfizer Ltd Method
CA2525517C (en) 2003-06-19 2016-05-31 Applied Research Systems Ars Holding N.V. Use of prion conversion modulating agents
FR2889533B1 (fr) * 2005-08-03 2007-10-12 Lab Francais Du Fractionnement Anticorps diriges contre le recepteur du ldl
FR2889532B1 (fr) * 2005-08-03 2007-10-12 Lab Francais Du Fractionnement Anticorps diriges contre le recepteur du ldl
WO2007094027A2 (en) * 2006-02-17 2007-08-23 Paolo La Colla Methods for the diagnosis of proliferative and/or conformational diseases
FR2910896B1 (fr) * 2006-12-29 2012-11-16 Lab Francais Du Fractionnement Anticorps monoclonal dirige contre le recepteur humain des ldl
IL182956A0 (en) 2007-05-03 2008-01-20 Yeda Res & Dev Glycan modified soluble receptors and binding proteins and their use
IL188628A0 (en) * 2008-01-07 2008-12-29 Yeda Res & Dev Use of soluble ldl-r for viral hepatitis
GB0922377D0 (en) * 2009-12-22 2010-02-03 Arab Gulf University The Mutant LDL receptor
BR112012029881A2 (pt) 2010-05-25 2019-09-24 Inserm (Institut National De La Santé De La Recherche Médicale) combinação de anticorpos anti-envelope e anticorpos anti-receptor para o tratamento e a presenção de infecção por hcv
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2013024157A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of host targeting agents for the treatment and the prevention of hcv infection
WO2013024155A1 (en) 2011-08-17 2013-02-21 Inserm (Institut National De La Sante Et De La Recherche Medicale) Combinations of anti-hcv-entry factor antibodies and direct acting antivirals for the treatment and the prevention of hcv infection
CN103111270B (zh) * 2013-02-26 2015-06-10 王业富 一种乙型肝炎抗原蛋白的吸附材料及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945308A (en) * 1998-04-03 1999-08-31 Incyte Pharmaceuticals, Inc. Human oxidized LDL receptor
JP2000279174A (ja) * 1999-03-30 2000-10-10 Bml Inc ヒトldlレセプターに対するモノクローナル抗体及びこれを用いる家族性高脂血症の判定方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182364A (en) * 1990-02-26 1993-01-26 The Scripps Research Institute Polypeptide analogs of apolipoprotein E
US5496926A (en) * 1992-01-19 1996-03-05 Yeda Research And Development Co. Ltd. Process of preparing a soluble LDL receptor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945308A (en) * 1998-04-03 1999-08-31 Incyte Pharmaceuticals, Inc. Human oxidized LDL receptor
JP2000279174A (ja) * 1999-03-30 2000-10-10 Bml Inc ヒトldlレセプターに対するモノクローナル抗体及びこれを用いる家族性高脂血症の判定方法

Also Published As

Publication number Publication date
IL139217A0 (en) 2001-11-25
WO2001068710A1 (en) 2001-09-20
RS51406B (sr) 2011-02-28
EA200200974A1 (ru) 2003-02-27
BG65762B1 (bg) 2009-10-30
DK1263790T3 (da) 2007-07-02
BR0109164A (pt) 2002-11-26
EE200200517A (et) 2004-02-16
ES2282238T3 (es) 2007-10-16
CZ20023098A3 (cs) 2003-02-12
AU4100201A (en) 2001-09-24
UA78489C2 (en) 2007-04-10
AU2001241002B2 (en) 2006-04-06
AR028518A1 (es) 2003-05-14
KR20020089384A (ko) 2002-11-29
JP4768193B2 (ja) 2011-09-07
HU226194B1 (hu) 2008-06-30
SI1263790T1 (sl) 2007-10-31
PT1263790E (pt) 2007-06-01
ATE362490T1 (de) 2007-06-15
US6849720B2 (en) 2005-02-01
SK287348B6 (sk) 2010-08-09
HUP0300142A3 (en) 2005-07-28
YU68602A (sh) 2006-03-03
AU2001241002B8 (en) 2006-05-04
HRP20020704A2 (en) 2004-12-31
NO20024223L (no) 2002-10-24
IL151713A0 (en) 2003-04-10
PL206041B1 (pl) 2010-06-30
NO330904B1 (no) 2011-08-15
EP1263790B1 (en) 2007-05-16
CN1418225B (zh) 2012-04-18
NZ520944A (en) 2004-04-30
PL358381A1 (en) 2004-08-09
CN1418225A (zh) 2003-05-14
EA007494B1 (ru) 2006-10-27
CA2402593C (en) 2012-07-03
EP1263790A1 (en) 2002-12-11
ZA200206654B (en) 2003-10-20
DE60128452D1 (de) 2007-06-28
CA2402593A1 (en) 2001-09-20
DE60128452T2 (de) 2007-09-13
NO20024223D0 (no) 2002-09-04
JP2004506603A (ja) 2004-03-04
KR100882081B1 (ko) 2009-02-10
CY1108020T1 (el) 2013-09-04
BG107063A (bg) 2003-05-30
HUP0300142A2 (hu) 2003-06-28
HK1055750A1 (en) 2004-01-21
SK13122002A3 (sk) 2003-04-01
US20030186343A1 (en) 2003-10-02
MXPA02009091A (es) 2005-06-20

Similar Documents

Publication Publication Date Title
HRP20020704B1 (en) Monoclonal antibodies to the human ldl receptor, their production and use
ATE303161T1 (de) Humanisierung von anti-carcinoembryonalen antigen anti-idiotypischen antikörper und dessen verwendung als tumorvakzin und zur markierung
RS51829B (sr) Ljudska antitela specifična za interleukin 15 (il-15)
EA201070623A1 (ru) Конструкция из полипептидов однодоменных антител, применение композиции, ее содержащей, и способ лечения ревматоидного артрита
SG165161A1 (en) Human monoclonal antibody against a costimulatory signal transduction molecule ailim and pharmaceutical use thereof
PT1639011E (pt) Anticorpos (dab) de domínio único peguilados
CR8698A (es) Anticuerpos monoclonales al factor de crecimiento de hepatocito
HUP0302376A2 (hu) Anti-TNF ellenanyagok, készítmények, eljárások és alkalmazások
DK1572748T3 (da) Humaniseret antistof (H14.18) af muse-14.18-antistof der binder til GD2 og dets fusionsprotein med IL-2
NZ594466A (en) Human monoclonal antibodies to protein tyrosine kinase 7 (PTK7) and methods for using anti-PTK7 antibodies
DE60130538D1 (de) Humanisierte antikörper gegen ccr2 und verfahren zur deren verwendung
MY145042A (en) Humanized monoclonal antibodies to hepatocyte growth factor
RS20060234A (en) Fully human antibodies against human 4-1bb (cd137)
NZ604090A (en) Human anti-b7rp1 neutralizing antibodies
DE69609188D1 (de) Neutralisierende monoklonale antikörper gegen respiratorischen synzytialvirus
WO2001068708A3 (en) Human and humanized fap-alpha-specific antibodies
DK1411962T3 (da) Terapi for pancreacancer med monoklonalt stof
NO986088D0 (no) Polypeptider med evnen til Õ danne antigenbindende strukturer med spesifisi
ATE148168T1 (de) Monoklonale antikörper
DK1167389T3 (da) Antistoffer mod SEMP1-proteinet, fremgangsmåde til fremstilling heraf samt anvendelse deraf
ATE477274T1 (de) Gegen clostridium difficile gerichtete antikörper
AU2005292852A8 (en) Method of immunizing animal, composition for immunization, method of producing antibody, method of producing hybridoma and method of producing monoclonal antibody
TH123607A (th) โมโนโคลนัลแอนติบอดี il-4 ในมนุษย์
UA93478C2 (ru) Выделенное моноклональное антитело человека, kotopoe связывается c cd20, и его применение

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PPPP Transfer of rights

Owner name: LABORATOIRES SERONO SA, CH

B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20150202

Year of fee payment: 15

PBON Lapse due to non-payment of renewal fee

Effective date: 20160308