HRP20020302B1 - Calcium complex of phosphorus containing ethylenediamine derivatives - Google Patents
Calcium complex of phosphorus containing ethylenediamine derivativesInfo
- Publication number
- HRP20020302B1 HRP20020302B1 HR20020302A HRP20020302A HRP20020302B1 HR P20020302 B1 HRP20020302 B1 HR P20020302B1 HR 20020302 A HR20020302 A HR 20020302A HR P20020302 A HRP20020302 A HR P20020302A HR P20020302 B1 HRP20020302 B1 HR P20020302B1
- Authority
- HR
- Croatia
- Prior art keywords
- kappa
- calcium complex
- phosphorus containing
- containing ethylenediamine
- ethylenediamine derivatives
- Prior art date
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052791 calcium Inorganic materials 0.000 title abstract 2
- 239000011575 calcium Substances 0.000 title abstract 2
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical class NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 title 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 title 1
- 239000011574 phosphorus Substances 0.000 title 1
- 229910052698 phosphorus Inorganic materials 0.000 title 1
- -1 carboxy- Chemical class 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910001385 heavy metal Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Absorbent Articles And Supports Therefor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1999144893 DE19944893C2 (de) | 1999-09-09 | 1999-09-09 | Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-. kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6, .kappa.N9,.kappa.O11]1-oxidato(6-)]-, hexahydrogen, dessen Salze und diese Komplexe enthaltende pharmazeutische Mittel |
| PCT/EP2000/008694 WO2001018011A1 (en) | 1999-09-09 | 2000-09-06 | Calcium complex of phosphorus containing ethylenediamine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20020302A2 HRP20020302A2 (en) | 2004-02-29 |
| HRP20020302B1 true HRP20020302B1 (en) | 2005-08-31 |
Family
ID=7922563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20020302A HRP20020302B1 (en) | 1999-09-09 | 2002-04-09 | Calcium complex of phosphorus containing ethylenediamine derivatives |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1210353B1 (sh) |
| JP (1) | JP2003508537A (sh) |
| KR (1) | KR100650090B1 (sh) |
| CN (1) | CN100341883C (sh) |
| AT (1) | ATE245159T1 (sh) |
| AU (1) | AU783982B2 (sh) |
| BG (1) | BG65280B1 (sh) |
| BR (1) | BR0013871A (sh) |
| CA (1) | CA2380766C (sh) |
| CZ (1) | CZ2002834A3 (sh) |
| DE (2) | DE19964224B4 (sh) |
| DK (1) | DK1210353T3 (sh) |
| EE (1) | EE05106B1 (sh) |
| ES (1) | ES2202178T3 (sh) |
| HK (1) | HK1050202A1 (sh) |
| HR (1) | HRP20020302B1 (sh) |
| HU (1) | HUP0202873A3 (sh) |
| IL (1) | IL148563A (sh) |
| MX (1) | MXPA02001583A (sh) |
| NO (1) | NO20021167D0 (sh) |
| NZ (1) | NZ517708A (sh) |
| PL (1) | PL354749A1 (sh) |
| PT (1) | PT1210353E (sh) |
| RS (1) | RS50125B (sh) |
| RU (1) | RU2247727C2 (sh) |
| SK (1) | SK3242002A3 (sh) |
| TW (1) | TWI263641B (sh) |
| UA (1) | UA74165C2 (sh) |
| WO (1) | WO2001018011A1 (sh) |
| ZA (1) | ZA200202742B (sh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201514188A (zh) * | 2013-03-13 | 2015-04-16 | Lantheus Medical Imaging Inc | 製備釓磷維塞三鈉單水合物之方法 |
| CN114845990A (zh) | 2019-12-20 | 2022-08-02 | 伯拉考成像股份公司 | 钙bopta配合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
| TW319763B (sh) * | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
| US5919967A (en) * | 1997-04-11 | 1999-07-06 | Epix Medical, Inc. | Process for synthesizing phosphodiesters |
-
1999
- 1999-09-09 DE DE19964224A patent/DE19964224B4/de not_active Expired - Fee Related
-
2000
- 2000-06-09 UA UA2002042826A patent/UA74165C2/uk unknown
- 2000-09-06 IL IL14856300A patent/IL148563A/en not_active IP Right Cessation
- 2000-09-06 BR BR0013871-1A patent/BR0013871A/pt not_active Application Discontinuation
- 2000-09-06 AT AT00967650T patent/ATE245159T1/de not_active IP Right Cessation
- 2000-09-06 RS YUP-161/02A patent/RS50125B/sr unknown
- 2000-09-06 DK DK00967650T patent/DK1210353T3/da active
- 2000-09-06 MX MXPA02001583A patent/MXPA02001583A/es active IP Right Grant
- 2000-09-06 WO PCT/EP2000/008694 patent/WO2001018011A1/en active IP Right Grant
- 2000-09-06 DE DE60003931T patent/DE60003931T2/de not_active Revoked
- 2000-09-06 CA CA002380766A patent/CA2380766C/en not_active Expired - Fee Related
- 2000-09-06 PL PL00354749A patent/PL354749A1/xx unknown
- 2000-09-06 ES ES00967650T patent/ES2202178T3/es not_active Expired - Lifetime
- 2000-09-06 EE EEP200200090A patent/EE05106B1/xx not_active IP Right Cessation
- 2000-09-06 CZ CZ2002834A patent/CZ2002834A3/cs unknown
- 2000-09-06 HU HU0202873A patent/HUP0202873A3/hu unknown
- 2000-09-06 NZ NZ517708A patent/NZ517708A/en unknown
- 2000-09-06 KR KR1020027003005A patent/KR100650090B1/ko not_active IP Right Cessation
- 2000-09-06 PT PT00967650T patent/PT1210353E/pt unknown
- 2000-09-06 JP JP2001522234A patent/JP2003508537A/ja active Pending
- 2000-09-06 RU RU2002107456/04A patent/RU2247727C2/ru not_active IP Right Cessation
- 2000-09-06 SK SK324-2002A patent/SK3242002A3/sk not_active Application Discontinuation
- 2000-09-06 CN CNB008126879A patent/CN100341883C/zh not_active Expired - Fee Related
- 2000-09-06 EP EP00967650A patent/EP1210353B1/en not_active Revoked
- 2000-09-06 AU AU77749/00A patent/AU783982B2/en not_active Ceased
- 2000-09-28 TW TW089118643A patent/TWI263641B/zh active
-
2002
- 2002-03-07 BG BG106488A patent/BG65280B1/bg unknown
- 2002-03-08 NO NO20021167A patent/NO20021167D0/no not_active Application Discontinuation
- 2002-04-08 ZA ZA200202742A patent/ZA200202742B/en unknown
- 2002-04-09 HR HR20020302A patent/HRP20020302B1/xx not_active IP Right Cessation
-
2003
- 2003-04-08 HK HK03102469A patent/HK1050202A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TNSN98203A1 (fr) | Derives de thienopyrimidine et tienopyridine utiles comme agents anticancereux, et compositions les contenant | |
| AU4925199A (en) | Quinolin-2-one derivatives useful as anticancer agents | |
| MX9503529A (es) | Derivados de glicinamida, procedimiento para su preparacion y medicamentos que los contienen. | |
| TNSN97144A1 (fr) | Derives 6,6-heterobicycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| TNSN98084A1 (fr) | Derives de macrolides substitues en position c-4 | |
| TNSN99162A1 (fr) | Derives de quinoleine-2-one a substituant alcynyle nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| HUT65192A (en) | Process for producing pyrido-, pyrrolo-, thiazino-, oxazino- and pyrazino benzazepine derivatives and pharmaceutical preparations containing | |
| TNSN97023A1 (fr) | Derives de triazole utiles en therapeutique, procedes pour leur preparation et compositions les contenant. | |
| IL117091A (en) | Methylphenyloxazolidinone derivatives pharmaceutical compositions containing the same and processes for the preparation threreof | |
| HU9601846D0 (en) | Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents | |
| AU6797298A (en) | Halo-alkoxycarbonyl prodrugs | |
| IL148563A0 (en) | Calcium complex of phosphorus containing ethylenediamine derivatives | |
| IL154755A0 (en) | Antitumor theraphy comprising distamycin derivatives | |
| HK1042430A1 (en) | Phospholipid complexes of proanthocyanidin a2 as antiatherosclerotic agents | |
| IL147890A0 (en) | Pharmaceutical compositions containing pentafluorobenzenesulfonamide derivatives | |
| AP2001002369A0 (en) | Pharmaceutical complex. | |
| FR2450840A1 (fr) | Complexes orthophosphates de cis-diammineplatine(ii) utiles comme medicaments et compositions pharmaceutiques les contenant | |
| WO1992019573A3 (en) | Multifunctional ligand for use as a diagnostic or therapeutic pharmaceutical | |
| TR200000753T2 (tr) | Mukabil antifungal ajan için prodrog olarak tetrahidrofuran fosfat ve hidroksi esterleri. | |
| UA40656C2 (uk) | Засіб "феррофол" для лікування залізодефіцитної анемії | |
| MX9709001A (es) | Composicion farmaceutica preparada por la adicion de un vehiculo saborizante para un medicamento. | |
| TNSN91040A1 (fr) | Derives de benzofuranne | |
| UA30361A (uk) | Спосіб лікування глікозидної інтоксикації |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| B1PR | Patent granted | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20080904 Year of fee payment: 9 |
|
| PNAN | Change of the applicant name, address/residence |
Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE |
|
| PBON | Lapse due to non-payment of renewal fee |
Effective date: 20090907 |