HRP20000765A2 - Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release - Google Patents

Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release Download PDF

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Publication number
HRP20000765A2
HRP20000765A2 HR20000765A HRP20000765A HRP20000765A2 HR P20000765 A2 HRP20000765 A2 HR P20000765A2 HR 20000765 A HR20000765 A HR 20000765A HR P20000765 A HRP20000765 A HR P20000765A HR P20000765 A2 HRP20000765 A2 HR P20000765A2
Authority
HR
Croatia
Prior art keywords
cyclodextrin
torasemide
derivatives
inclusion complexes
cyclodextrins
Prior art date
Application number
HR20000765A
Other languages
English (en)
Croatian (hr)
Inventor
Dumić Miljenko
Filić Darko
Klepić Božena
Danilovski Aleksandar
Tu­A Marija
Original Assignee
Pliva D D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva D D filed Critical Pliva D D
Priority to HR20000765A priority Critical patent/HRP20000765A2/hr
Priority to ARP010100079A priority patent/AR026815A1/es
Priority to JP2002540768A priority patent/JP2004513155A/ja
Priority to ZA200303601A priority patent/ZA200303601B/xx
Priority to EP01993478A priority patent/EP1347780B1/en
Priority to BR0115281-5A priority patent/BR0115281A/pt
Priority to MXPA03004111A priority patent/MXPA03004111A/es
Priority to YU35303A priority patent/YU35303A/sh
Priority to EEP200300197A priority patent/EE200300197A/xx
Priority to AU2001228721A priority patent/AU2001228721A1/en
Priority to HU0400776A priority patent/HUP0400776A2/hu
Priority to PCT/HR2001/000004 priority patent/WO2002038186A1/en
Priority to SK672-2003A priority patent/SK6722003A3/sk
Priority to CNA018198309A priority patent/CN1477977A/zh
Priority to EA200300556A priority patent/EA005111B1/ru
Priority to IL15581801A priority patent/IL155818A0/xx
Priority to PL01361667A priority patent/PL361667A1/xx
Priority to KR10-2003-7006357A priority patent/KR20030060929A/ko
Priority to CZ20031490A priority patent/CZ20031490A3/cs
Priority to DE60125828T priority patent/DE60125828T2/de
Priority to GE5156A priority patent/GEP20043403B/en
Priority to US10/416,303 priority patent/US7037928B2/en
Priority to CA002428179A priority patent/CA2428179A1/en
Publication of HRP20000765A2 publication Critical patent/HRP20000765A2/hr
Priority to IS6810A priority patent/IS6810A/is
Priority to NO20032091A priority patent/NO20032091L/no
Priority to BG107896A priority patent/BG107896A/bg

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HR20000765A 2000-11-10 2000-11-10 Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release HRP20000765A2 (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
HR20000765A HRP20000765A2 (en) 2000-11-10 2000-11-10 Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release
ARP010100079A AR026815A1 (es) 2000-11-10 2001-01-09 Composiciones de n-(1-metiletilaminocaarbonil)-4-(3-metilfenilamino)-3-piridil-sulfonamida y oligosacaridos ciclicos con una mayor liberacion
CNA018198309A CN1477977A (zh) 2000-11-10 2001-01-31 N-(甲基乙基氨基羰基)-4-(3-甲基苯基氨基)-3-吡啶基磺酰胺及环状低聚糖的组合物
IL15581801A IL155818A0 (en) 2000-11-10 2001-01-31 Compositions of n-(methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridyl-sulfonamide and cyclic oligosaccharides
EP01993478A EP1347780B1 (en) 2000-11-10 2001-01-31 Compositions of n-(methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides
BR0115281-5A BR0115281A (pt) 2000-11-10 2001-01-31 Composições de n-(metiletilaminocarbonil)-4-(3-metilfenilamino)-3piri dilsulfonamida e oligossacarìdeos cìclicos
MXPA03004111A MXPA03004111A (es) 2000-11-10 2001-01-31 Composiciones de n-(1 -metiletilaminocarbonil)-4 -(3-metilfenilamino) -3-piridil-sulfonamida y oligosacaridos ciclicos con una mayor liberacion.
YU35303A YU35303A (sh) 2000-11-10 2001-01-31 Preparati n-(1-metiletilaminokarbonil)-4-(3-metilfenil-amino)-3-piridinsulfonamida i cikličnih oligosaharida
EEP200300197A EE200300197A (et) 2000-11-10 2001-01-31 Torasemiidi ja tsüklodekstriinide või tsüklodekstriini derivaatide füüsikalised segud ja klatraadid, nende valmistamine ja kasutamine ning neid sisaldav ravimvorm
AU2001228721A AU2001228721A1 (en) 2000-11-10 2001-01-31 Compositions of N-(methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridyl-sulfonamide and cyclic oligosaccharides
HU0400776A HUP0400776A2 (hu) 2000-11-10 2001-01-31 N-(Metiletilaminokarbonil)-4-(3-metilfenilamino)-3-piridilszulfonamid és gyűrűs oligoszacharidok kompozíciói, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
PCT/HR2001/000004 WO2002038186A1 (en) 2000-11-10 2001-01-31 Compositions of n-(methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides
SK672-2003A SK6722003A3 (en) 2000-11-10 2001-01-31 Physical mixtures and inclusion complexes comprising torasemide and cyclodextrins or cyclodextrin derivatives, method of producing thereof and pharmaceutical compositions comprising the same
JP2002540768A JP2004513155A (ja) 2000-11-10 2001-01-31 N−(メチルエチルアミノカルボニル)−4−(3−メチルフェニルアミノ)−3−ピリジルスルホンアミドと環状オリゴ糖の組成物
EA200300556A EA005111B1 (ru) 2000-11-10 2001-01-31 Композиции n-(метилэтиламинокарбонил)-4-(3-метилфениламино)-3-пиридилсульфонамида и циклических олигосахаридов
ZA200303601A ZA200303601B (en) 2000-11-10 2001-01-31 Compositions of N-(methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides.
PL01361667A PL361667A1 (en) 2000-11-10 2001-01-31 Compositions of n-(methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides
KR10-2003-7006357A KR20030060929A (ko) 2000-11-10 2001-01-31 N-(메틸에틸아미노카르보닐)-4-(3-메틸페닐아미노)-3-피리딜술폰아미드 및 시클릭 올리고사카라이드의 조성물
CZ20031490A CZ20031490A3 (cs) 2000-11-10 2001-01-31 Fyzikální směsi a inkluzní komplexy obsahující torasemid a cyklodextriny nebo cyklodextrinové deriváty, způsoby jejich výroby a farmaceutické formy je obsahující
DE60125828T DE60125828T2 (de) 2000-11-10 2001-01-31 Zusammensetzungen aus n-(methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamid und zyklischen oligonukleotiden
GE5156A GEP20043403B (en) 2000-11-10 2001-01-31 Compositions Of N-(Methyl-ethylaminocarbonyl)-4-(3-Methyl-phenylamino)-3-Pyridyl-Sulfonamide (Torasemide) and Cyclic Oligosaccharides
US10/416,303 US7037928B2 (en) 2000-11-10 2001-01-31 Compositions of N-(methylethylaminocarbonyl)-4-(-3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides
CA002428179A CA2428179A1 (en) 2000-11-10 2001-01-31 Compositions of n-(methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides
IS6810A IS6810A (is) 2000-11-10 2003-05-08 Samsetningar af N-(metýletýlamínókarbónýl)-4-(3-metýlfenýlamínó)-3-pýridýl-súlfonamíði og hringlagafásykrum
NO20032091A NO20032091L (no) 2000-11-10 2003-05-09 Blandinger av N-(metyletylaminokarbonyl)-4-(3- metylfenylamino)-3-pyridylsulfonamid og sykliske oligosakkarider
BG107896A BG107896A (bg) 2000-11-10 2003-06-10 Състави на n-(метилетиламинокарбонил)-4-(3-метилфениламино)-3-пиридил-сулфона мид и циклични олигозахариди

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR20000765A HRP20000765A2 (en) 2000-11-10 2000-11-10 Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release

Publications (1)

Publication Number Publication Date
HRP20000765A2 true HRP20000765A2 (en) 2002-06-30

Family

ID=10947206

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000765A HRP20000765A2 (en) 2000-11-10 2000-11-10 Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release

Country Status (26)

Country Link
US (1) US7037928B2 (hu)
EP (1) EP1347780B1 (hu)
JP (1) JP2004513155A (hu)
KR (1) KR20030060929A (hu)
CN (1) CN1477977A (hu)
AR (1) AR026815A1 (hu)
AU (1) AU2001228721A1 (hu)
BG (1) BG107896A (hu)
BR (1) BR0115281A (hu)
CA (1) CA2428179A1 (hu)
CZ (1) CZ20031490A3 (hu)
DE (1) DE60125828T2 (hu)
EA (1) EA005111B1 (hu)
EE (1) EE200300197A (hu)
GE (1) GEP20043403B (hu)
HR (1) HRP20000765A2 (hu)
HU (1) HUP0400776A2 (hu)
IL (1) IL155818A0 (hu)
IS (1) IS6810A (hu)
MX (1) MXPA03004111A (hu)
NO (1) NO20032091L (hu)
PL (1) PL361667A1 (hu)
SK (1) SK6722003A3 (hu)
WO (1) WO2002038186A1 (hu)
YU (1) YU35303A (hu)
ZA (1) ZA200303601B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI21703A (en) * 2004-01-14 2005-08-31 Lek Farmacevtska Druzba Dd Inclusion complexes of perindopril, procedure of their preparation, pharmaceutical compositions containing these complexes and their application in treatment of hypertensia
DE602005002930T2 (de) * 2004-01-22 2008-07-24 Pfizer Inc. Sulfonamidderivate zur behandlung von krankheiten
CN100372534C (zh) * 2006-04-20 2008-03-05 南京海辰药业有限公司 托拉塞米冻干制剂及制备方法
EP2591783A1 (en) 2007-04-13 2013-05-15 Millennium Pharmaceuticals, Inc. Combination anticoagulant therapy with a compound that acts as a factor Xa inhibitor
BR102012009317B1 (pt) * 2012-04-20 2022-05-31 Universidade Federal De Minas Gerais - Ufmg Processo de preparação de compostos de inclusão envolvendo ciclodextrinas e fármacos, usando um sistema de fluxo contínuo
WO2020141224A1 (en) 2019-01-04 2020-07-09 Sq Innovation Ag Pharmaceutical compositions of furosemide and uses thereof
EP3906020A1 (en) * 2019-01-04 2021-11-10 SQ Innovation AG Pharmaceutical compositions of torsemide and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US576511A (en) * 1897-02-02 Georg steinike and friedrich schmidt
DE3529529A1 (de) * 1985-08-17 1987-02-19 Boehringer Mannheim Gmbh Verfahren zur herstellung einer stabilen modifikation von torasemid
WO1997021312A2 (en) * 1995-12-01 1997-06-12 Philips Electronics N.V. A digital cordless telephony system, a radio base station, and a combination of a radio base station and a cordless handset
US6828334B2 (en) * 2002-05-23 2004-12-07 Usv Limited Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition

Also Published As

Publication number Publication date
NO20032091D0 (no) 2003-05-09
PL361667A1 (en) 2004-10-04
KR20030060929A (ko) 2003-07-16
GEP20043403B (en) 2004-06-10
EP1347780B1 (en) 2007-01-03
EA200300556A1 (ru) 2003-08-28
DE60125828D1 (de) 2007-02-15
MXPA03004111A (es) 2004-05-05
JP2004513155A (ja) 2004-04-30
BG107896A (bg) 2004-01-30
DE60125828T2 (de) 2007-08-16
HUP0400776A2 (hu) 2004-08-30
CA2428179A1 (en) 2002-05-16
YU35303A (sh) 2006-03-03
ZA200303601B (en) 2004-07-19
CZ20031490A3 (cs) 2003-08-13
EE200300197A (et) 2003-08-15
EA005111B1 (ru) 2004-10-28
WO2002038186A1 (en) 2002-05-16
IS6810A (is) 2003-05-08
BR0115281A (pt) 2003-07-29
AU2001228721A1 (en) 2002-05-21
US20040039204A1 (en) 2004-02-26
IL155818A0 (en) 2003-12-23
SK6722003A3 (en) 2003-10-07
US7037928B2 (en) 2006-05-02
CN1477977A (zh) 2004-02-25
EP1347780A1 (en) 2003-10-01
NO20032091L (no) 2003-07-02
AR026815A1 (es) 2003-02-26

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