HK86988A - A process for the preparation of alpha-6-deoxytetracyclines - Google Patents

A process for the preparation of alpha-6-deoxytetracyclines

Info

Publication number
HK86988A
HK86988A HK869/88A HK86988A HK86988A HK 86988 A HK86988 A HK 86988A HK 869/88 A HK869/88 A HK 869/88A HK 86988 A HK86988 A HK 86988A HK 86988 A HK86988 A HK 86988A
Authority
HK
Hong Kong
Prior art keywords
deoxytetracyclines
alpha
preparation
Prior art date
Application number
HK869/88A
Other languages
English (en)
Inventor
Philip Ronald Page
Ivan Vilax
Original Assignee
Plurichemie Anstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PT198274303A external-priority patent/PT74303B/pt
Priority claimed from PT198276061A external-priority patent/PT76061A/pt
Application filed by Plurichemie Anstalt filed Critical Plurichemie Anstalt
Publication of HK86988A publication Critical patent/HK86988A/xx

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/26—Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups B01J31/02 - B01J31/24
    • B01J31/28—Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups B01J31/02 - B01J31/24 of the platinum group metals, iron group metals or copper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/18—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
    • B01J31/1805—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms the ligands containing nitrogen
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/18—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60—Reduction reactions, e.g. hydrogenation
    • B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/645—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80—Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82—Metals of the platinum group
    • B01J2531/822—Rhodium
HK869/88A 1982-01-19 1988-10-27 A process for the preparation of alpha-6-deoxytetracyclines HK86988A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT198274303A PT74303B (fr) 1982-01-19 1982-01-19 Procede pour la preparation de nouveaux catalysateurs contenant rhodium et son utilisation
PT198276061A PT76061A (en) 1982-12-30 1982-12-30 Stable homogeneous hydrogenation rhodium catalyst - useful in high yield prodn. of doxycycline by stereospecific hydrogenation

Publications (1)

Publication Number Publication Date
HK86988A true HK86988A (en) 1988-11-04

Family

ID=26653435

Family Applications (1)

Application Number Title Priority Date Filing Date
HK869/88A HK86988A (en) 1982-01-19 1988-10-27 A process for the preparation of alpha-6-deoxytetracyclines

Country Status (7)

Country Link
US (2) US4500458A (de)
EP (1) EP0086046B1 (de)
KR (1) KR870000210B1 (de)
DE (1) DE3372183D1 (de)
FR (1) FR2530490B1 (de)
HK (1) HK86988A (de)
SG (1) SG68089G (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT79774A (en) * 1984-12-28 1985-01-01 Joao Emerico Villax Process to prepare rhodium catalysts and applications thereof
US4500458A (en) * 1982-01-19 1985-02-19 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
PT76061A (en) * 1982-12-30 1983-01-01 Stable homogeneous hydrogenation rhodium catalyst - useful in high yield prodn. of doxycycline by stereospecific hydrogenation
PT74303B (fr) * 1982-01-19 1983-08-08 Joao Emerico Villax Procede pour la preparation de nouveaux catalysateurs contenant rhodium et son utilisation
US4743699A (en) * 1982-01-19 1988-05-10 Plurichemie Anstalt Homogeneous catalytic system and a process for the preparation of same
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
US4863639A (en) * 1987-03-25 1989-09-05 Plurichemie Anstalt Application of catalysts containing rhodium
DE3771705D1 (de) * 1987-03-25 1991-08-29 Plurichemie Anstalt Rhodiumhydrierungskatalysatoren.
ATE63312T1 (de) * 1987-03-25 1991-05-15 Plurichemie Anstalt Rhodium enthaltende hydrierungskatalysatoren.
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
US4902447A (en) * 1988-10-28 1990-02-20 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines and hydrogenation catalyst useful therein
DE68900339D1 (de) * 1989-04-03 1991-11-21 Ranbaxy Lab Ltd Verfahren zur herstellung von alpha-6-deoxytetracyclinen.
DE19644050A1 (de) * 1996-10-31 1998-05-07 Bayer Ag Verfahren zur Herstellung von Ivermectin
EP1157740A3 (de) 2000-05-18 2002-02-27 Haldor Topsoe A/S Rhodium enthaltenden Lösungen
WO2005011707A1 (en) * 2003-07-25 2005-02-10 Warner Chilcott Company, Inc. A doxycycline metal complex in a solid dosage form
PL2342223T3 (pl) 2008-09-26 2017-09-29 Ambrx, Inc. Zmodyfikowane polipeptydy zwierzęcej erytropoetyny i ich zastosowania
US8729058B2 (en) 2009-10-27 2014-05-20 Michael Zasloff Methods and compositions for treating and preventing viral infections
CN106946728B (zh) * 2017-04-12 2019-02-01 扬州联博药业有限公司 一种生产多西环素一水合物的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA668581A (en) * 1963-08-13 R. D. Mccormick Jerry Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
GB1154937A (en) * 1966-08-10 1969-06-11 Ici Ltd Hydrogenation Process
US3755194A (en) * 1969-02-12 1973-08-28 O Eremenko Hydrogenation catalyst
CA942743A (en) * 1970-07-03 1974-02-26 Ivan Villax Process for producing 6-methylenetetracyclines and 6-deoxytetracyclines
NL7109740A (de) * 1971-02-24 1972-08-28
US3956177A (en) * 1971-08-20 1976-05-11 Phillips Petroleum Company Rhodium hydroformylation catalyst
US4207258A (en) * 1972-02-24 1980-06-10 Ankerfarm S.P.A. Process for the preparatin of α-6-deoxytetracyclines
GB1440372A (en) * 1973-02-01 1976-06-23 Pfizer Process for the preparation of tetracyclines
SE435619C (sv) * 1973-02-01 1985-10-31 Pfizer Forfarande for framstellning av en 6alfa-deoxitetracyklin
US3954862A (en) * 1973-04-20 1976-05-04 Pfizer Inc. Process for producing α-6-deoxytetracyclines
US3907890A (en) * 1974-05-28 1975-09-23 Pfizer Preparation of alpha-6-deoxy-5-hydroxytetracycline
CH619443A5 (en) * 1974-10-31 1980-09-30 Hoffmann La Roche Process for the preparation of optically active alkane- and alkene monocarboxylic acids.
US4001321A (en) * 1975-06-26 1977-01-04 Pfizer Inc. Preparation of α-6-deoxytetracyclines
US3962131A (en) * 1975-01-28 1976-06-08 Pfizer Inc. Rhodium containing catalyst and use thereof in preparation of 6-deoxy-5-oxytetracycline
US3978000A (en) * 1975-03-19 1976-08-31 American Cyanamid Company Catalysts based on carbon supports
US4500458A (en) * 1982-01-19 1985-02-19 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines

Also Published As

Publication number Publication date
EP0086046A1 (de) 1983-08-17
KR840003038A (ko) 1984-08-13
SG68089G (en) 1990-01-26
EP0086046B1 (de) 1987-06-24
DE3372183D1 (en) 1987-07-30
FR2530490A1 (fr) 1984-01-27
US4500458A (en) 1985-02-19
KR870000210B1 (ko) 1987-02-17
FR2530490B1 (fr) 1987-12-24
US4550096A (en) 1985-10-29

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Legal Events

Date Code Title Description
PE Patent expired