HK86090A - N-phenylmethylalkadienamide derivatives and compositions for use as analgesics - Google Patents

N-phenylmethylalkadienamide derivatives and compositions for use as analgesics Download PDF

Info

Publication number
HK86090A
HK86090A HK860/90A HK86090A HK86090A HK 86090 A HK86090 A HK 86090A HK 860/90 A HK860/90 A HK 860/90A HK 86090 A HK86090 A HK 86090A HK 86090 A HK86090 A HK 86090A
Authority
HK
Hong Kong
Prior art keywords
pharmaceutically
alkadienamides
compositions
acceptable salts
phenylmethylalkadienamide
Prior art date
Application number
HK860/90A
Other languages
English (en)
Inventor
Robert Lahann Thomas
Michael Janusz John
Lee Buckwalter Brian
Original Assignee
The Procter & Gamble Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Procter & Gamble Company filed Critical The Procter & Gamble Company
Publication of HK86090A publication Critical patent/HK86090A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK860/90A 1983-07-14 1990-10-18 N-phenylmethylalkadienamide derivatives and compositions for use as analgesics HK86090A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/514,207 US4544669A (en) 1983-07-14 1983-07-14 Compounds and compositions useful for producing analgesia

Publications (1)

Publication Number Publication Date
HK86090A true HK86090A (en) 1990-10-25

Family

ID=24046232

Family Applications (1)

Application Number Title Priority Date Filing Date
HK860/90A HK86090A (en) 1983-07-14 1990-10-18 N-phenylmethylalkadienamide derivatives and compositions for use as analgesics

Country Status (15)

Country Link
US (1) US4544669A (OSRAM)
EP (1) EP0132346B1 (OSRAM)
JP (1) JPS6075454A (OSRAM)
AU (1) AU561216B2 (OSRAM)
CA (1) CA1244047A (OSRAM)
DE (1) DE3460819D1 (OSRAM)
DK (1) DK164851C (OSRAM)
GB (1) GB2144414B (OSRAM)
HK (1) HK86090A (OSRAM)
IE (1) IE57566B1 (OSRAM)
MY (1) MY102023A (OSRAM)
NZ (1) NZ208898A (OSRAM)
PH (1) PH21840A (OSRAM)
SG (1) SG44390G (OSRAM)
ZA (1) ZA845266B (OSRAM)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493848A (en) * 1983-07-14 1985-01-15 The Procter & Gamble Company Compositions and methods useful for producing analgesia
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
DE3563617D1 (en) * 1984-12-20 1988-08-11 Procter & Gamble Compounds and compositions having anti-inflammatory and analgesic activity
US4885027A (en) * 1985-04-05 1989-12-05 Chevron Research Company Herbicidal arylmethylenesulfonamido-acetamide and thioacetamide derivatives
GB2178031B (en) 1985-06-10 1989-07-26 Procter & Gamble Phenylacetic acid amides having anti-inflammatory and analgesic activity
US4990533A (en) * 1985-12-20 1991-02-05 Warner-Lambert Co. Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US4980366A (en) * 1986-08-19 1990-12-25 Warner-Lambert Co. Amide, sulfonamide, urea, carbamate, thiocarbamate, and thiourea derivatives of 4'hydroxybenzylamine having anti-inflammatory and analgesic activity
US5045565A (en) * 1987-03-09 1991-09-03 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5099030A (en) * 1987-03-09 1992-03-24 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5461075A (en) * 1988-06-17 1995-10-24 The Procter & Gamble Company Use of vanilloids for the prevention of lesions due to herpes simplex infections
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US6248788B1 (en) 1996-11-06 2001-06-19 The Regents Of The University Of California Therapeutic method with capsaicin and capasicin analogs
US6239180B1 (en) 1995-11-08 2001-05-29 The Regents Of The University Of California Transdermal therapeutic device and method with capsaicin and capsaicin analogs
AU7389098A (en) 1997-05-16 1998-12-08 Brigham And Women's Hospital Local anesthetic formulations
US6689399B1 (en) 2000-03-16 2004-02-10 James R. Dickson Transdermal delivery of an anti-inflammatory composition
WO2002067966A1 (en) 2001-02-22 2002-09-06 Purdue Research Foundation Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer
US7192612B2 (en) * 2001-02-22 2007-03-20 Purdue Research Foundation Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer
CA2522028C (en) 2003-04-10 2011-11-01 Neurogesx, Inc. Methods and compositions for administration of trpv1 agonists
WO2006060505A2 (en) * 2004-12-01 2006-06-08 Dacanay Rhodel G Capsaicin nutritional supplement
EP1858495A2 (en) * 2005-02-14 2007-11-28 Neurogesx, Inc. Device for delivery of trpv1 agonists
EP1865933B1 (en) * 2005-03-30 2015-11-04 Vanderbilt Royalty Sub L.P. Low-concentration capsaicin patch and methods for treating neuropathic pain
AU2006241176A1 (en) * 2005-04-25 2006-11-02 Neurogesx, Inc. TRPV1 agonist compounds and methods for making and using the same
US8952152B2 (en) 2009-03-24 2015-02-10 Proteus S.A. Methods for purifying phycotoxins, pharmaceutical compositions containing purified phycotoxins, and methods of use thereof
HRP20171744T1 (hr) 2010-07-27 2018-01-12 Flex Pharma, Inc. Postupci i pripravci za spriječavanje i ublažavanje grčeva mišića i za oporavak od neuromišićne nadraženosti i umora nakon vježbanja
WO2012075337A2 (en) 2010-12-01 2012-06-07 Spinal Modulation, Inc. Directed delivery of agents to neural anatomy
AU2014232881B2 (en) 2013-03-15 2017-04-27 The Children's Medical Center Corporation Neosaxitoxin combination formulations for prolonged local anesthesia
CN103739511A (zh) * 2013-12-20 2014-04-23 白城艾高食品有限公司 一种萃取辣椒碱的方法
CN105439889B (zh) * 2015-11-20 2017-08-22 安徽省逸欣铭医药科技有限公司 一种香兰素胺类新化合物、其制备方法及医药用途
WO2018136943A1 (en) 2017-01-23 2018-07-26 Flex Pharma, Inc. Compositions and methods affecting exercise performance

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE938014C (de) * 1952-11-05 1956-01-19 Beiersdorf & Co A G P Verfahren zur Herstellung kristallisierter Vanillylamide
DE1166766B (de) * 1961-08-04 1964-04-02 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen Phenylalkylcarbonsaeureamiden
JPS4218610B1 (OSRAM) * 1964-08-28 1967-09-23
US3621043A (en) * 1963-02-06 1971-11-16 Sumitomo Chemical Co N-substituted octadecadienoic acid amides as cholesterol lowering agents
NL130295C (OSRAM) * 1964-04-28
SE353319B (OSRAM) * 1964-08-15 1973-01-29 Sumitomo Chemical Co
US3558500A (en) * 1968-02-07 1971-01-26 Buckman Labor Inc Method for the control of scale using n,n-dimethylamides of 18 carbon unsaturated carboxylic acids
US3920523A (en) * 1971-03-17 1975-11-18 Akzona Inc Thin film evaporation of a crude amide feed in mixture with an alkali metal hydroxide
US3888893A (en) * 1971-06-14 1975-06-10 John B Siddall Unsaturated amides
US3816484A (en) * 1971-10-08 1974-06-11 Zoecon Corp Aliphatic hydrocarbon 2,4-dienamides
US3803185A (en) * 1971-11-22 1974-04-09 Zoecon Corp Novel 2,4-dienamides
JPS5619344B2 (OSRAM) * 1972-11-11 1981-05-07
DE2752366A1 (de) * 1977-11-24 1979-05-31 Bayer Ag 3,3-dimethyl-4-penten-thiosaeureamide und verfahren zu ihrer herstellung
US4238508A (en) * 1979-08-17 1980-12-09 The Research Foundation Of State University Of New York Method for analgesia using 3-hydroxyacetanilide
US4313958A (en) * 1980-10-24 1982-02-02 The Procter & Gamble Company Method of producing analgesia
US4401663A (en) * 1981-06-30 1983-08-30 The Procter & Gamble Company Novel sulfonamide derivatives

Also Published As

Publication number Publication date
AU3058584A (en) 1985-01-17
PH21840A (en) 1988-03-17
SG44390G (en) 1990-12-21
JPS6075454A (ja) 1985-04-27
US4544669A (en) 1985-10-01
EP0132346A1 (en) 1985-01-30
EP0132346B1 (en) 1986-09-24
NZ208898A (en) 1988-03-30
MY102023A (en) 1992-02-29
GB2144414A (en) 1985-03-06
DE3460819D1 (en) 1986-10-30
GB8417624D0 (en) 1984-08-15
CA1244047A (en) 1988-11-01
DK345784A (da) 1985-01-15
DK164851C (da) 1993-01-18
GB2144414B (en) 1987-11-11
IE57566B1 (en) 1992-12-16
DK164851B (da) 1992-08-31
DK345784D0 (da) 1984-07-13
IE841813L (en) 1985-01-14
AU561216B2 (en) 1987-04-30
JPH0510334B2 (OSRAM) 1993-02-09
ZA845266B (en) 1985-03-27

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)