HK6190A - Pharmaceutical compositions containing n-substituted-3-hydroxypyrid-2-one or -4-one derivatives - Google Patents

Pharmaceutical compositions containing n-substituted-3-hydroxypyrid-2-one or -4-one derivatives Download PDF

Info

Publication number
HK6190A
HK6190A HK61/90A HK6190A HK6190A HK 6190 A HK6190 A HK 6190A HK 61/90 A HK61/90 A HK 61/90A HK 6190 A HK6190 A HK 6190A HK 6190 A HK6190 A HK 6190A
Authority
HK
Hong Kong
Prior art keywords
hydroxypyrid
carbon atoms
hydroxy
aliphatic hydrocarbon
hydrocarbon group
Prior art date
Application number
HK61/90A
Other languages
German (de)
English (en)
French (fr)
Inventor
Robert Charles Hider
George Kontoghiorghes
Jack Silver
Original Assignee
Btg International Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Btg International Limited filed Critical Btg International Limited
Publication of HK6190A publication Critical patent/HK6190A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
HK61/90A 1982-03-24 1990-01-25 Pharmaceutical compositions containing n-substituted-3-hydroxypyrid-2-one or -4-one derivatives HK6190A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8208608 1982-03-24

Publications (1)

Publication Number Publication Date
HK6190A true HK6190A (en) 1990-02-02

Family

ID=10529232

Family Applications (1)

Application Number Title Priority Date Filing Date
HK61/90A HK6190A (en) 1982-03-24 1990-01-25 Pharmaceutical compositions containing n-substituted-3-hydroxypyrid-2-one or -4-one derivatives

Country Status (8)

Country Link
US (1) US4840958A (instruction)
EP (1) EP0093498B1 (instruction)
JP (3) JPS58174319A (instruction)
CY (1) CY1502A (instruction)
DE (2) DE3367849D1 (instruction)
GR (1) GR78491B (instruction)
HK (1) HK6190A (instruction)
NL (1) NL990031I2 (instruction)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308054D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
GB8308055D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
EP0305646B1 (en) * 1983-03-24 1996-11-13 Btg International Limited 3-Hydroxypyrid-4-ones and pharmaceutical compositions
GB8325494D0 (en) * 1983-09-23 1983-10-26 Hider R C Pharmaceutical compositions
US4912118A (en) * 1983-09-23 1990-03-27 National Research Development Corporation Pharmaceutical compositions
USRE34313E (en) * 1983-09-23 1993-07-13 National Research Development Corporation Pharmaceutical compositions
WO1989009211A1 (en) * 1988-03-31 1989-10-05 The Royal Free Hospital School Of Medicine Process for producing pyrid-4-ones
GB8910521D0 (en) * 1989-05-08 1989-06-21 Nat Res Dev The stabilization of organic compounds
US5298525A (en) * 1992-11-23 1994-03-29 University Technologies International, Inc. Diabetes prevention and treatment
US6046219A (en) * 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5849587A (en) * 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
EP0833627B1 (en) 1995-06-10 2004-08-18 Vitra Pharmaceuticals Ltd. Iron compounds, compositions, methods of making the same and uses thereof
US6004986A (en) * 1997-05-08 1999-12-21 The University Of Virginia Patent Foundation Method for treating cerebral vasospasm and cerebral ischemia using iron chelators and pharmaceutical compositions therefor
US6767741B1 (en) * 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
IL135884A (en) * 2000-04-30 2005-08-31 Yissum Res Dev Co Method for measuring non-transferrin bound iron
CA2421410C (en) * 2000-09-19 2009-11-10 Vitra Pharmaceuticals Limited Iron compositions
US6426418B1 (en) 2001-11-02 2002-07-30 Apotex, Inc. Processes for the manufacturing of 3-hydroxy-N,1,6-trialkyl-4-oxo-1,4-dihydropyridine-2-carboxamide
GB0211500D0 (en) 2002-05-18 2002-06-26 Vitra Pharmaceuticals Ltd Method of forming iron hydroxypyrone compounds
CA2504512A1 (en) 2002-10-30 2004-05-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Molecules and methods using same for measuring non-transferrin bound iron
WO2004041151A2 (en) 2002-11-07 2004-05-21 Technion Research And Development Foundation Ltd. Neuroprotective iron chelators and pharmaceutical compositions comprising them
CA2488034C (en) * 2004-11-19 2009-10-06 Apotex Inc. Process for the manufacture of 3-hydroxy-n-alkyl-1-cycloalkyl-6-alkyl-4-oxo-1,4-dihydropyridine-2-carboxamide and its related analogues
KR20130044381A (ko) * 2010-03-04 2013-05-02 머크 샤프 앤드 돔 코포레이션 카테콜 o-메틸 트랜스퍼라제의 억제제 및 정신병적 장애의 치료에서의 그의 용도
GB201007209D0 (en) 2010-04-29 2010-06-16 King S College London Compound
WO2012137202A1 (en) 2011-04-05 2012-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Composition comprising an iron indicator attached to a microparticle and uses of same for quantifying non-transferrin bound iron (ntbi) and cellular labile iron (lci)
WO2018085619A1 (en) * 2016-11-07 2018-05-11 Arbutus Biopharma, Inc. Substituted pyridinone-containing tricyclic compounds, and methods using same
TWI801517B (zh) 2018-03-12 2023-05-11 加拿大商愛彼特生物製藥公司 經取代的2-吡啶酮三環化合物、其類似物及其使用方法
CN112839654A (zh) 2018-04-12 2021-05-25 爱彼特生物制药公司 制备取代的含吡啶酮的三环化合物的方法

Also Published As

Publication number Publication date
DE3367849D1 (en) 1987-01-15
NL990031I1 (nl) 1999-12-01
JPH0680636A (ja) 1994-03-22
NL990031I2 (nl) 2000-04-03
US4840958A (en) 1989-06-20
EP0093498A3 (en) 1984-07-11
JPH0460987B2 (instruction) 1992-09-29
JPS58174318A (ja) 1983-10-13
DE19975062I1 (de) 2003-09-04
JPS58174319A (ja) 1983-10-13
CY1502A (en) 1990-08-03
JPH0515693B2 (instruction) 1993-03-02
EP0093498A2 (en) 1983-11-09
EP0093498B1 (en) 1986-11-26
JPH0757749B2 (ja) 1995-06-21
GR78491B (instruction) 1984-09-27

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