HK35697A - Cyclosporin compositions - Google Patents
Cyclosporin compositions Download PDFInfo
- Publication number
- HK35697A HK35697A HK35697A HK35697A HK35697A HK 35697 A HK35697 A HK 35697A HK 35697 A HK35697 A HK 35697A HK 35697 A HK35697 A HK 35697A HK 35697 A HK35697 A HK 35697A
- Authority
- HK
- Hong Kong
- Prior art keywords
- cyclosporin
- acid
- composition according
- glyceride
- fatty acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1912588 | 1988-01-29 | ||
JP11163988 | 1988-05-10 | ||
JP63183127A JP2632010B2 (ja) | 1988-01-29 | 1988-07-22 | シクロスポリン製剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK35697A true HK35697A (en) | 1997-03-27 |
Family
ID=27282507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK35697A HK35697A (en) | 1988-01-29 | 1997-03-20 | Cyclosporin compositions |
Country Status (8)
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5639724A (en) | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
US6007840A (en) * | 1988-09-16 | 1999-12-28 | Novartis Ag | Pharmaceutical compositions comprising cyclosporins |
KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
US5342625A (en) * | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
US7081445B2 (en) * | 1989-02-20 | 2006-07-25 | Novartis Ag | Cyclosporin galenic forms |
US5294604A (en) * | 1989-12-20 | 1994-03-15 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating ocular diseases by periocular administration of cyclosporine A or G |
EP0448091B1 (en) * | 1990-03-23 | 1998-08-05 | The Green Cross Corporation | Pharmaceutical composition containing slightly water-soluble drug |
CA2102704A1 (en) * | 1991-05-17 | 1992-11-18 | John Stephen Haskill | Inhibitor of nf-kb transcriptional activator and uses thereof |
US6262022B1 (en) | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
DE69307505T2 (de) | 1992-05-13 | 1997-07-24 | Sandoz-Patent-Gmbh, 79539 Loerrach | Opthalmische zusammensetzungen enthaltend ein cyclosporin |
EP0589843B1 (en) | 1992-09-25 | 2001-11-28 | Novartis AG | Pharmaceutical compositions containing cyclosporins |
WO1994008538A1 (en) * | 1992-10-22 | 1994-04-28 | Aktsionernoe Obschestvo 'olvik' | Medicinal ocular membrane and method of producing the same |
ATE218878T1 (de) † | 1993-04-20 | 2002-06-15 | Novartis Erfind Verwalt Gmbh | Neue pharmazeutische zubereitungen zur oralen verabreichung enthaltend cyclosporin |
US20020099067A1 (en) * | 1993-07-08 | 2002-07-25 | Ulrich Posanski | Pharmaceutical compositions for sparingly soluble therapeutic agents |
DE4322826A1 (de) * | 1993-07-08 | 1995-01-12 | Galenik Labor Freiburg Gmbh | Pharmazeutisches Präparat |
ES2308955T5 (es) * | 1993-09-28 | 2012-04-03 | R.P. Scherer Gmbh | Fabricación de cápsulas de gelatina blanda |
PH31594A (en) * | 1993-09-30 | 1998-11-03 | Janssen Pharmaceutica Nv | Oral formulations on an antifungal. |
FR2711982B1 (fr) * | 1993-11-02 | 1996-01-19 | Saint Gobain Vitrage | Canal de transfert et de conditionnement de verre en fusion. |
WO1995025504A1 (en) * | 1994-03-18 | 1995-09-28 | Pharmavene, Inc. | Emulsified drug delivery systems |
US5474979A (en) * | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
EP0789580B1 (de) | 1994-11-03 | 2002-06-05 | Novartis AG | Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung |
US5824638A (en) * | 1995-05-22 | 1998-10-20 | Shire Laboratories, Inc. | Oral insulin delivery |
US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
US5827822A (en) * | 1996-03-25 | 1998-10-27 | Sangstat Medical Corporation | Cyclosporin a formulations as nanoparticles |
US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
US5766629A (en) | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
EP0760237A1 (en) * | 1995-08-30 | 1997-03-05 | Cipla Limited | Oil-in-water microemulsions |
DE19544507B4 (de) | 1995-11-29 | 2007-11-15 | Novartis Ag | Cyclosporin enthaltende Präparate |
CZ288631B6 (cs) * | 1996-01-18 | 2001-08-15 | Galena, A. S. | Léčivé přípravky s obsahem cyklosporinu |
US5858401A (en) * | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
US5660858A (en) * | 1996-04-03 | 1997-08-26 | Research Triangle Pharmaceuticals | Cyclosporin emulsions |
US7255877B2 (en) * | 1996-08-22 | 2007-08-14 | Jagotec Ag | Fenofibrate microparticles |
CA2263102C (en) | 1996-08-22 | 2006-08-15 | Research Triangle Pharmaceuticals Ltd. | Compositions comprising microparticles of water-insoluble substances and method for preparing same |
US6465016B2 (en) | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
CN1246058A (zh) | 1997-01-30 | 2000-03-01 | 诺瓦提斯公司 | 包含环孢菌素a的无油药物组合物 |
DE19724605A1 (de) * | 1997-06-11 | 1998-12-17 | Sueddeutsche Kalkstickstoff | Hydrophile, homogene Monogycerid-Formulierungen und Verfahren zu deren Herstellung |
US6187747B1 (en) | 1997-09-08 | 2001-02-13 | Panacea Biotech Limited | Pharmaceutical composition comprising cyclosporin |
US6346511B1 (en) | 1997-09-08 | 2002-02-12 | Panacea Biotec Limited | Pharmaceutical composition comprising cyclosporin |
US6008191A (en) * | 1997-09-08 | 1999-12-28 | Panacea Biotec Limited | Pharmaceutical compositions containing cyclosporin |
IN188719B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1997-09-08 | 2002-11-02 | Panacea Biotec Ltd | |
AU743098B2 (en) | 1997-12-10 | 2002-01-17 | Cyclosporine Therapeutics Limited | Pharmaceutical compositions containing an omega-3 fatty acid oil |
DE19810655A1 (de) * | 1998-03-12 | 1999-09-16 | Univ Eberhard Karls | Arzneimittel mit einem Gehalt an Ciclosporin |
US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
CN1245955C (zh) | 1998-05-29 | 2006-03-22 | 斯凯伊药品加拿大公司 | 热保护微粒组合物及其最终蒸汽灭菌的方法 |
EP0976394A1 (en) * | 1998-07-30 | 2000-02-02 | Biosearch Italia S.p.A. | New injectable formulations |
RU2233654C2 (ru) | 1998-11-20 | 2004-08-10 | Ртп Фарма Инк. | Диспергируемые стабилизированные фосфолипидом микрочастицы |
CA2354233A1 (en) | 1998-12-11 | 2000-06-15 | Pharmasolutions, Inc. | Self-emulsifying compositions for drugs poorly soluble in water |
US6447806B1 (en) | 1999-02-25 | 2002-09-10 | Novartis Ag | Pharmaceutical compositions comprised of stabilized peptide particles |
US6057289A (en) * | 1999-04-30 | 2000-05-02 | Pharmasolutions, Inc. | Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system |
EP1214059B1 (en) * | 1999-09-21 | 2005-05-25 | Skyepharma Canada Inc. | Surface modified particulate compositions of biologically active substances |
US6720001B2 (en) | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
AU2127400A (en) * | 1999-11-02 | 2001-05-14 | Cipla Limited | A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and process for preparation thereof |
US7732404B2 (en) * | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
GB0008785D0 (en) * | 2000-04-10 | 2000-05-31 | Novartis Ag | Organic compounds |
CA2423336C (en) * | 2000-09-20 | 2011-03-08 | Rtp Pharma Inc. | Stabilised fibrate microparticles |
US8586094B2 (en) * | 2000-09-20 | 2013-11-19 | Jagotec Ag | Coated tablets |
HRP20040354B1 (en) * | 2001-10-19 | 2012-10-31 | Isotechnika Inc. | Novel cyclosporin analog microemulsion preconcentrates |
US6979672B2 (en) | 2002-12-20 | 2005-12-27 | Polichem, S.A. | Cyclosporin-based pharmaceutical compositions |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
US7151085B2 (en) * | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
CN101141953A (zh) | 2005-03-21 | 2008-03-12 | 伊瓦克斯制药有限公司 | 结晶抑制剂及其在明胶胶囊中的用途 |
GB2451811A (en) | 2007-08-09 | 2009-02-18 | Ems Sa | Delivery composition for solubilising water-insoluble pharmaceutical active ingredients |
PT3556774T (pt) | 2011-03-11 | 2024-02-29 | Beth Israel Deaconess Medical Ct Inc | Anticorpos anti-cd40 e suas utilizações |
EP3197865A1 (en) | 2014-09-26 | 2017-08-02 | The Chemours Company FC, LLC | Sulfonated fluorinated, non-fluorinated or partially fluorinated urethanes |
KR102779818B1 (ko) | 2015-09-04 | 2025-03-11 | 프리마토프 테라퓨틱스 인크. | 인간화 항-cd40 항체 및 그의 용도 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE149197C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1902-10-24 | |||
US2865859A (en) * | 1956-11-09 | 1958-12-23 | Irwin I Lubowe | Solubilizing of mineral, vegetable, animal oils for cosmetic, pharmaceutical and industrial purposes |
US3678149A (en) * | 1970-01-26 | 1972-07-18 | Samuel J Prigal | Method of enhancing the action of a medicament |
FI65914C (fi) * | 1978-03-07 | 1984-08-10 | Sandoz Ag | Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a |
CH641356A5 (en) * | 1979-02-27 | 1984-02-29 | Sandoz Ag | Pharmaceutical compositions containing cyclosporin |
US4659696A (en) * | 1982-04-30 | 1987-04-21 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition and its nasal or vaginal use |
JPS5921613A (ja) * | 1982-07-28 | 1984-02-03 | Takeda Chem Ind Ltd | 直腸投与製剤 |
DE3372705D1 (en) * | 1982-04-30 | 1987-09-03 | Takeda Chemical Industries Ltd | Pharmaceutical composition and its use |
US4474751A (en) * | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Ophthalmic drug delivery system utilizing thermosetting gels |
BE897724A (fr) * | 1983-09-09 | 1984-01-02 | Mallien Denis | Systeme de communication selective, bidirectionnelle, par radio, entre un poste de commande et plusieurs postes de travail |
DE3339236A1 (de) * | 1983-10-28 | 1985-05-09 | Bayer Ag | Arzneimittelzubereitung |
US4612193A (en) * | 1983-12-23 | 1986-09-16 | Del Laboratories, Inc. | Sty ointment and method of using the same |
US4722914A (en) * | 1984-05-30 | 1988-02-02 | Motorola Inc. | Method of making a high density IC module assembly |
DE3580717D1 (de) * | 1984-08-02 | 1991-01-10 | Sandoz Ag | Pharmazeutische anwendung von (nva)2-cyclosporine. |
US4649047A (en) * | 1985-03-19 | 1987-03-10 | University Of Georgia Research Foundation, Inc. | Ophthalmic treatment by topical administration of cyclosporin |
US4839342A (en) * | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
-
1989
- 1989-01-27 ES ES198989300856T patent/ES2033086T3/es not_active Expired - Lifetime
- 1989-01-27 AU AU28853/89A patent/AU609242B2/en not_active Expired
- 1989-01-27 EP EP89300856A patent/EP0327280B1/en not_active Expired
- 1989-01-27 CA CA000589378A patent/CA1326995C/en not_active Expired - Lifetime
- 1989-01-27 DE DE8989300856T patent/DE68900991D1/de not_active Expired - Lifetime
-
1990
- 1990-04-12 US US07/511,992 patent/US4990337A/en not_active Expired - Lifetime
-
1992
- 1992-05-18 GR GR920400935T patent/GR3004611T3/el unknown
-
1997
- 1997-03-20 HK HK35697A patent/HK35697A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GR3004611T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-04-28 |
US4990337A (en) | 1991-02-05 |
AU609242B2 (en) | 1991-04-26 |
EP0327280A1 (en) | 1989-08-09 |
ES2033086T3 (es) | 1993-03-01 |
DE68900991D1 (de) | 1992-04-23 |
AU2885389A (en) | 1989-08-03 |
EP0327280B1 (en) | 1992-03-18 |
CA1326995C (en) | 1994-02-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0327280B1 (en) | Cyclosporin compositions | |
EP0874621B1 (en) | [3'-DESOXY-3-OXO-MeBmT]1-[Val]2-CICLOSPORIN-CONTAINING EMULSION PHARMACEUTICAL COMPOSITIONS | |
CN1229136C (zh) | 供局部施用于眼组织的泪腺特异性乳状液 | |
US5589455A (en) | Cyclosporin-containing soft capsule compositions | |
US5843891A (en) | Pharmaceutical acceptable compositions containing an alcohol and a hydrophobic drug | |
EP1039893B1 (en) | Pharmaceutical compositions containing an omega-3 fatty acid oil | |
CA2162993C (en) | Solid fat nanoemulsions as drug delivery vehicles | |
EP0711550B1 (en) | Cyclosporin-containing soft capsule compositions | |
EP0650721B1 (en) | Cyclosporin soft capsule | |
EP0215313A2 (en) | Emulsion compositions for the parenteral and/or oral administration of sparingly water soluble ionizable hydrophobic drugs | |
CA2313015A1 (en) | Cyclosporin-containing microemulsion preconcentrate composition | |
PT100400B (pt) | Formulacoes de microemulsoes convertiveis | |
CA2283780A1 (en) | Lipophilic binary systems for the administration of lipophilic compounds | |
WO1994014415A1 (en) | Fluorocarbon emulsions | |
JPH0157096B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
SK2482002A3 (en) | Pharmaceutical compositions for oral and topical administration | |
EP0331755A1 (en) | Medicine-containing fat emulsion of the type prepared immediately before use and process for preparing medicine-containing fat emulsion | |
SK37198A3 (en) | Cyclosporin-containing soft capsule preparations | |
KR20010023360A (ko) | 혈관신생 촉진제 | |
JP2632010B2 (ja) | シクロスポリン製剤 | |
JP3074732B2 (ja) | 脂肪乳剤 | |
JPH04253907A (ja) | 静脈注射用免疫抑制剤 | |
JPH01113315A (ja) | ビタミンk↓2含有脂肪乳剤 | |
SK123299A3 (en) | Pharmaceutical compositions containing cyclosporin | |
AU753018B2 (en) | Cyclosporin-containing soft capsule preparations |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20090126 |