HK161295A - Vector for integration site independent gene expression in mammalian host cells - Google Patents

Vector for integration site independent gene expression in mammalian host cells

Info

Publication number
HK161295A
HK161295A HK161295A HK161295A HK161295A HK 161295 A HK161295 A HK 161295A HK 161295 A HK161295 A HK 161295A HK 161295 A HK161295 A HK 161295A HK 161295 A HK161295 A HK 161295A
Authority
HK
Hong Kong
Prior art keywords
mammalian host
vector
integration site
gene expression
host cells
Prior art date
Application number
HK161295A
Other languages
English (en)
Inventor
Franklin Gerardus Grosveld
Dimitris Kioussis
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10621987&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK161295(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medical Res Council filed Critical Medical Res Council
Publication of HK161295A publication Critical patent/HK161295A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70507—CD2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Animal Husbandry (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK161295A 1987-08-07 1995-10-12 Vector for integration site independent gene expression in mammalian host cells HK161295A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878718779A GB8718779D0 (en) 1987-08-07 1987-08-07 Dna sequence & expression vector
PCT/GB1988/000655 WO1989001517A1 (fr) 1987-08-07 1988-08-08 Vecteur pour une expression de gene independante du site d'integration dans des cellules hotes de mammiferes

Publications (1)

Publication Number Publication Date
HK161295A true HK161295A (en) 1995-10-20

Family

ID=10621987

Family Applications (1)

Application Number Title Priority Date Filing Date
HK161295A HK161295A (en) 1987-08-07 1995-10-12 Vector for integration site independent gene expression in mammalian host cells

Country Status (8)

Country Link
EP (2) EP0332667B2 (fr)
JP (3) JP3181049B2 (fr)
AT (1) ATE120486T1 (fr)
CA (1) CA1336269C (fr)
DE (1) DE3853474T3 (fr)
GB (1) GB8718779D0 (fr)
HK (1) HK161295A (fr)
WO (1) WO1989001517A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048729A (en) 1987-05-01 2000-04-11 Transkaryotic Therapies, Inc. In vivo protein production and delivery system for gene therapy
AU6505690A (en) * 1989-09-26 1991-04-28 Richard R Behringer Erythroid-specific gene expression system
WO1991013151A1 (fr) * 1990-02-22 1991-09-05 Biogen, Inc. Expression amelioree de polypeptides
GB9027917D0 (en) * 1990-12-21 1991-02-13 Ici Plc Expression systems
US5922854A (en) * 1991-06-14 1999-07-13 Kumar; Ramesh Purifying Human Hemogloblin from transgenic pig red cells and plasmids containing pig globin nucleic acids
US6270989B1 (en) 1991-11-05 2001-08-07 Transkaryotic Therapies, Inc. Protein production and delivery
US5641670A (en) * 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US6063630A (en) 1991-11-05 2000-05-16 Transkaryotic Therapies, Inc. Targeted introduction of DNA into primary or secondary cells and their use for gene therapy
US5968502A (en) 1991-11-05 1999-10-19 Transkaryotic Therapies, Inc. Protein production and protein delivery
US6692737B1 (en) 1991-11-05 2004-02-17 Transkaryotic Therapies, Inc. In vivo protein production and delivery system for gene therapy
US6054288A (en) * 1991-11-05 2000-04-25 Transkaryotic Therapies, Inc. In vivo protein production and delivery system for gene therapy
PT101031B (pt) 1991-11-05 2002-07-31 Transkaryotic Therapies Inc Processo para o fornecimento de proteinas por terapia genetica
US6531124B1 (en) 1992-07-10 2003-03-11 Transkaryotic Therapies, Inc. In vivo production and delivery of insulinotropin for gene therapy
US6670178B1 (en) 1992-07-10 2003-12-30 Transkaryotic Therapies, Inc. In Vivo production and delivery of insulinotropin for gene therapy
US5631162A (en) * 1993-06-11 1997-05-20 Massachusetts Institute Of Technology Retroviral vectors for transducing β-globin gene and β-locus control region derivatives
GB9319772D0 (en) * 1993-09-24 1993-11-10 Therexsys Ltd Therapeutic agent
US5627268A (en) * 1994-06-07 1997-05-06 Dnx Biotherapeutics Hemoglobin comprising globin fusion proteins
US5821351A (en) * 1994-06-10 1998-10-13 Dnx Biotherapeutics Production of hemoglobin having a delta-like globin
WO1998045322A2 (fr) * 1997-04-10 1998-10-15 Royal Netherlands Academy Of Arts And Sciences Reactifs pour diagnostics et procede correspondant
WO2000005393A2 (fr) 1998-07-21 2000-02-03 Cobra Therapeutics Limited Polynucleotide comportant un element d'ouverture de la chromatine ubiquiste (ucoe)
CN108012545B (zh) * 2015-03-31 2022-08-30 葛莱高托普有限公司 包含珠蛋白基因簇的调控元件的真核表达载体
USD937539S1 (en) * 2020-02-18 2021-12-07 Traci Sawtelle Wearable towel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE123059T1 (de) * 1987-09-17 1995-06-15 Massachusetts Inst Technology Menschliche, erythroid-spezifische transkriptionsenhancer.

Also Published As

Publication number Publication date
DE3853474T2 (de) 1995-09-21
GB8718779D0 (en) 1987-09-16
DE3853474D1 (de) 1995-05-04
EP0332667B1 (fr) 1995-03-29
JPH10113177A (ja) 1998-05-06
ATE120486T1 (de) 1995-04-15
JP3181049B2 (ja) 2001-07-03
EP0332667A1 (fr) 1989-09-20
JP2000245462A (ja) 2000-09-12
CA1336269C (fr) 1995-07-11
DE3853474T3 (de) 1999-07-08
EP0668357A1 (fr) 1995-08-23
EP0332667B2 (fr) 1998-12-09
JPH02500802A (ja) 1990-03-22
WO1989001517A1 (fr) 1989-02-23

Similar Documents

Publication Publication Date Title
HK161295A (en) Vector for integration site independent gene expression in mammalian host cells
NO964445D0 (no) DNA-sekvens, vektor, vertscelle og fremgangsmåte for transfeksjon av hematopoeseceller med eksogen DNA
ES8305413A1 (es) Un metodo para estabilizar y seleccionar celulas huesped quecontienen un adn recombinante
FI883722A0 (fi) Alfa-amiderande enzymkompositioner och foerfaranden foer deras framstaellning och anvaendning.
AU8065782A (en) Expression of exogenous polypeptides in yeast
IL68366A (en) Process for expressing a gene encoding a protein comprising the enzymatic portion of human urokinase in a microorganism or cell culture
EP0325474A3 (en) Receptor protein for human b cell stimulating factor-2
GR3024271T3 (en) Interleukin-4 receptors
SG122763A1 (en) Production of proteins using homologous recombination
ES8604308A1 (es) Un vector para producir un producto genetico por celulas de insectos
EP0244234A3 (en) Transformation of trichoderma
AU3668389A (en) Exogenous gene expression vector containing chick beta-actin gene promoter
ATE244311T1 (de) Expressionssystem von antikörpern bei homologischer rekombinierung in murinezellen
ES2123569T3 (es) Regulacion de genes en celulas de mamifero dependiente de ecdiesteroides.
EP0363127A3 (fr) Expression dans des eucaryotes
IL86058A0 (en) Production of proteins
CA1312566C (en) Method for increasing the expression of polypeptides in recombinant cell culture
AU6698090A (en) Bacterial collagenase gene
AU589151B2 (en) New expression control sequence
EP0350052A3 (fr) Animaux transgéniques transformés avec un plasmide contenant une séquence à réplication autonome
AU6295390A (en) Cell culture methods for producing activated protein c
NZ332555A (en) Gene expression in monocytes and macrophages associated with the CD68 gene

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20060808