HK127993A - Mitomycin analogs, a process for preparing them and pharmaceutical compositions - Google Patents

Mitomycin analogs, a process for preparing them and pharmaceutical compositions Download PDF

Info

Publication number
HK127993A
HK127993A HK1279/93A HK127993A HK127993A HK 127993 A HK127993 A HK 127993A HK 1279/93 A HK1279/93 A HK 1279/93A HK 127993 A HK127993 A HK 127993A HK 127993 A HK127993 A HK 127993A
Authority
HK
Hong Kong
Prior art keywords
mitomycin
compound
methyl
compounds
amino
Prior art date
Application number
HK1279/93A
Other languages
German (de)
English (en)
French (fr)
Inventor
Takushi Kaneko
Henry S.L. Wong
Terrence W. Doyle
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of HK127993A publication Critical patent/HK127993A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
HK1279/93A 1987-06-12 1993-11-18 Mitomycin analogs, a process for preparing them and pharmaceutical compositions HK127993A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6183987A 1987-06-12 1987-06-12

Publications (1)

Publication Number Publication Date
HK127993A true HK127993A (en) 1993-11-26

Family

ID=22038465

Family Applications (1)

Application Number Title Priority Date Filing Date
HK1279/93A HK127993A (en) 1987-06-12 1993-11-18 Mitomycin analogs, a process for preparing them and pharmaceutical compositions

Country Status (10)

Country Link
US (1) US5374739A (cs)
EP (1) EP0294828B1 (cs)
JP (1) JPS63316781A (cs)
AT (1) ATE93524T1 (cs)
CA (1) CA1326487C (cs)
CY (1) CY1742A (cs)
DE (1) DE3883434T2 (cs)
ES (1) ES2058182T3 (cs)
HK (1) HK127993A (cs)
IL (1) IL86665A0 (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495348B1 (en) * 1993-10-07 2002-12-17 Regents Of The University Of Minnesota Mitomycin biosynthetic gene cluster
US6524812B1 (en) 1993-10-07 2003-02-25 Regents Of The University Of Minnesota Genes encoding resistance to DNA alkylating agents
WO2004028589A2 (en) 2002-09-26 2004-04-08 Endovascular Devices, Inc. Apparatus and method for delivery of mitomycin through an eluting biocompatible implantable medical device

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129868C (cs) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) * 1964-08-25 1969-01-07 Kyowa Hakko Kogyo Kk 7-substituted mitomycin a
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4460599A (en) * 1979-12-05 1984-07-17 University Patents, Inc. Mitomycin analogs
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4567256A (en) * 1983-05-09 1986-01-28 Bristol-Myers Company Amidine process
US4579737A (en) * 1983-05-09 1986-04-01 Bristol-Myers Company Bis-amidines
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
FR2571373A1 (fr) * 1984-10-09 1986-04-11 Bristol Myers Co Procede de preparation de derives n7-substitues de la mitomycine c

Also Published As

Publication number Publication date
ES2058182T3 (es) 1994-11-01
ATE93524T1 (de) 1993-09-15
DE3883434T2 (de) 1993-12-09
US5374739A (en) 1994-12-20
EP0294828B1 (en) 1993-08-25
CY1742A (en) 1995-10-20
DE3883434D1 (de) 1993-09-30
CA1326487C (en) 1994-01-25
EP0294828A3 (en) 1990-05-09
EP0294828A2 (en) 1988-12-14
IL86665A0 (en) 1988-11-30
JPH0563476B2 (cs) 1993-09-10
JPS63316781A (ja) 1988-12-26

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PE Patent expired

Effective date: 20080609