HK1254779A1 - 抗rsv融合前f蛋白的免疫球蛋白單可變結構域抗體 - Google Patents

抗rsv融合前f蛋白的免疫球蛋白單可變結構域抗體

Info

Publication number
HK1254779A1
HK1254779A1 HK18113825.4A HK18113825A HK1254779A1 HK 1254779 A1 HK1254779 A1 HK 1254779A1 HK 18113825 A HK18113825 A HK 18113825A HK 1254779 A1 HK1254779 A1 HK 1254779A1
Authority
HK
Hong Kong
Prior art keywords
protein
variable domain
antibody against
single variable
domain antibody
Prior art date
Application number
HK18113825.4A
Other languages
English (en)
Inventor
Xavier Saelens
Bert Schepens
Iebe Rossey
Barney Graham
Jason Mclellan
Morgan Gilman
Original Assignee
Vib Vzw
Univ Gent
Us Health
Dartmouth College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57545045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1254779(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP15178653.0A external-priority patent/EP3124042A1/en
Application filed by Vib Vzw, Univ Gent, Us Health, Dartmouth College filed Critical Vib Vzw
Publication of HK1254779A1 publication Critical patent/HK1254779A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18113825.4A 2015-06-18 2018-10-30 抗rsv融合前f蛋白的免疫球蛋白單可變結構域抗體 HK1254779A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562181522P 2015-06-18 2015-06-18
EP15178653.0A EP3124042A1 (en) 2015-07-28 2015-07-28 Immunoglobulin single variable domain antibody against rsv prefusion f protein
EP15191868 2015-10-28
PCT/EP2016/064218 WO2016203052A1 (en) 2015-06-18 2016-06-20 Immunoglobulin single variable domain antibody against rsv prefusion f protein

Publications (1)

Publication Number Publication Date
HK1254779A1 true HK1254779A1 (zh) 2019-07-26

Family

ID=57545045

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18113825.4A HK1254779A1 (zh) 2015-06-18 2018-10-30 抗rsv融合前f蛋白的免疫球蛋白單可變結構域抗體

Country Status (18)

Country Link
US (2) US10501528B2 (zh)
EP (1) EP3313432A1 (zh)
JP (1) JP6836760B2 (zh)
KR (1) KR20180056631A (zh)
CN (1) CN108472343B (zh)
AU (1) AU2016277887B2 (zh)
BR (1) BR112017027303A2 (zh)
CA (1) CA2989378A1 (zh)
CL (1) CL2017003260A1 (zh)
HK (1) HK1254779A1 (zh)
IL (1) IL256315B2 (zh)
MA (1) MA42246A (zh)
MX (1) MX2017016590A (zh)
MY (1) MY192870A (zh)
PH (1) PH12017502356B1 (zh)
RU (1) RU2730671C2 (zh)
UA (1) UA123584C2 (zh)
WO (1) WO2016203052A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180056631A (ko) * 2015-06-18 2018-05-29 브이아이비 브이지더블유 Rsv 프리퓨전 f 단백질에 대한 면역글로불린 단일 가변 도메인 항체
CN111808187B (zh) * 2019-08-02 2022-05-17 苏州高泓利康生物科技有限公司 针对呼吸道合胞病毒的蛋白结合分子
CN116063468A (zh) * 2022-08-30 2023-05-05 武汉班科生物技术有限公司 中和呼吸道合胞病毒的c-型单域抗体及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1997830A1 (en) 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV specific binding molecules and means for producing them
AU2008340949A1 (en) * 2007-12-24 2009-07-02 Glaxosmithkline Biologicals S.A. Recombinant RSV antigens
PT2285408T (pt) 2008-06-05 2019-02-01 Ablynx Nv Sequências de aminoácidos dirigidas contra proteínas de envelope de um vírus e polipéptidos que as compreendem para o tratamento de doenças virais
DK2438087T3 (en) * 2009-06-05 2017-08-28 Ablynx Nv TRIVALENT NANOBODY CONSTRUCTIONS AGAINST HUMAN RESPIRATORY SYNCYTIAL VIRUS (HRSV) FOR PREVENTION AND / OR TREATMENT OF AIR INFECTIONS
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
US9644022B2 (en) * 2009-11-30 2017-05-09 Ablynx N.V. Amino acid sequences directed against human respiratory syncytial virus (HRSV) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
KR20180056631A (ko) * 2015-06-18 2018-05-29 브이아이비 브이지더블유 Rsv 프리퓨전 f 단백질에 대한 면역글로불린 단일 가변 도메인 항체

Also Published As

Publication number Publication date
AU2016277887B2 (en) 2022-06-09
US11248039B2 (en) 2022-02-15
UA123584C2 (uk) 2021-04-28
CL2017003260A1 (es) 2018-05-11
RU2018101662A3 (zh) 2019-11-06
US10501528B2 (en) 2019-12-10
IL256315B2 (en) 2023-12-01
MX2017016590A (es) 2018-11-09
AU2016277887A1 (en) 2018-01-18
CN108472343A (zh) 2018-08-31
PH12017502356A1 (en) 2018-06-25
PH12017502356B1 (en) 2018-06-25
BR112017027303A2 (pt) 2018-09-04
US20180179266A1 (en) 2018-06-28
CA2989378A1 (en) 2016-12-22
MY192870A (en) 2022-09-13
IL256315B1 (en) 2023-08-01
CN108472343B (zh) 2021-12-10
EP3313432A1 (en) 2018-05-02
KR20180056631A (ko) 2018-05-29
RU2018101662A (ru) 2019-07-22
WO2016203052A1 (en) 2016-12-22
JP2018524979A (ja) 2018-09-06
IL256315A (en) 2018-02-28
MA42246A (fr) 2018-05-02
RU2730671C2 (ru) 2020-08-24
JP6836760B2 (ja) 2021-03-03
US20200102374A1 (en) 2020-04-02

Similar Documents

Publication Publication Date Title
ZA201900353B (en) Anti-pd-l1 antibodies
IL262295A (en) Antibodies against pd-l1
IL262092A (en) Human anti-pacap antibodies and their use
SI3512547T1 (sl) Anti-PD-1 protitelesa
EP3532100A4 (en) ANTI-PD-L1 ANTIBODIES AND VARIANTS
EP3387442A4 (en) HUMANIZED ANTI-CD73 ANTIBODIES
EP3433277A4 (en) NEW ANTIBODIES AGAINST PD-L1
EP3242894A4 (en) Anti-pd-l1 antibodies
EP3441086A4 (en) MONOCLONAL ANTI-PD-1 ANTIBODY
GB201721338D0 (en) Anti-icos Antibodies
KR20180085002A (ko) 인간화된 항-cll-1 항체
EP3532489A4 (en) ANTI-TL1A NEUTRALIZING MONOCLONAL ANTIBODIES
ZA201901865B (en) Anti-pd-1 antibodies
GB201506409D0 (en) Humanized anti-axl antibodies and their conjugates
DK3464331T3 (da) Stabiliserede præfusions-rsv f-proteiner
IL262776A (en) Human anti-il-1r3 antibodies
EP3567053A4 (en) MONOCLONAL ANTI-CLAUDIN-2 ANTIBODY
IL258924A (en) Humanized anti-Dicoff-related protein 2 antibody and uses thereof
IL267271A (en) Antibodies against il-5
HK1254779A1 (zh) 抗rsv融合前f蛋白的免疫球蛋白單可變結構域抗體
ITUB20155097A1 (it) Anticorpi umanizzati anti-BAG3
EP3149046A4 (en) Humanized anti-cd19 antibody and use thereof
EP3498838A4 (en) ANTI-PD-L1 ANTIBODIES
EP3498839A4 (en) ANTI-PD-1 ANTIBODIES
EP3330376A4 (en) ANTI-EVA 1 PROTEIN ANTIBODY