HK1251583A1 - 在親和層析中減少宿主細胞蛋白的方法 - Google Patents

在親和層析中減少宿主細胞蛋白的方法

Info

Publication number
HK1251583A1
HK1251583A1 HK18110895.5A HK18110895A HK1251583A1 HK 1251583 A1 HK1251583 A1 HK 1251583A1 HK 18110895 A HK18110895 A HK 18110895A HK 1251583 A1 HK1251583 A1 HK 1251583A1
Authority
HK
Hong Kong
Prior art keywords
reduction
host cell
affinity chromatography
cell proteins
proteins
Prior art date
Application number
HK18110895.5A
Other languages
English (en)
Inventor
Roberto Falkenstein
Wolfgang Koehnlein
Klaus Schwendner
Bernhard Spensberger
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54064133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1251583(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1251583A1 publication Critical patent/HK1251583A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK18110895.5A 2015-08-21 2018-08-23 在親和層析中減少宿主細胞蛋白的方法 HK1251583A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15181903 2015-08-21
PCT/EP2016/069163 WO2017032611A1 (en) 2015-08-21 2016-08-11 Method for the reduction of host cell proteins in affinity chromatography

Publications (1)

Publication Number Publication Date
HK1251583A1 true HK1251583A1 (zh) 2019-02-01

Family

ID=54064133

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18110895.5A HK1251583A1 (zh) 2015-08-21 2018-08-23 在親和層析中減少宿主細胞蛋白的方法

Country Status (10)

Country Link
US (2) US20180186865A1 (zh)
EP (1) EP3337817B1 (zh)
JP (1) JP7073253B2 (zh)
CN (1) CN107835819A (zh)
ES (1) ES2897965T3 (zh)
HK (1) HK1251583A1 (zh)
HR (1) HRP20211737T1 (zh)
PL (1) PL3337817T3 (zh)
SI (1) SI3337817T1 (zh)
WO (1) WO2017032611A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2992420A1 (en) 2015-08-21 2017-03-02 F. Hoffmann-La Roche Ag Method for the reduction of host cell proteins in affinity chromatography
CN112876567A (zh) * 2019-11-29 2021-06-01 广东菲鹏制药股份有限公司 Fc融合蛋白及其纯化方法
CN114901671B (zh) * 2020-01-20 2024-02-20 上海药明生物技术有限公司 用于亲和层析的新的清洗缓冲溶液

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9203459D0 (en) * 1992-02-19 1992-04-08 Scotgen Ltd Antibodies with germ-line variable regions
TWI338009B (en) 2001-10-29 2011-03-01 Genentech Inc Antibodies for inhibiting blood coagulation and methods of use thereof
EP2261230B1 (en) * 2002-09-11 2017-05-10 Chugai Seiyaku Kabushiki Kaisha Protein purification method
TW200902555A (en) 2005-01-03 2009-01-16 Hoffmann La Roche Antibodies against IL-13 receptor alpha 1 and uses thereof
PL1876236T3 (pl) 2005-04-08 2015-01-30 Chugai Pharmaceutical Co Ltd Przeciwciała zastępujące czynność czynnika krzepnięcia VIII
RU2415865C2 (ru) 2005-06-17 2011-04-10 Вайет СПОСОБЫ ОЧИСТКИ БЕЛКОВ, СОДЕРЖАЩИХ ОБЛАСТЬ Fc
KR20110079693A (ko) 2008-10-29 2011-07-07 와이어쓰 엘엘씨 단일 도메인 항원 결합 분자의 정제 방법
WO2011038894A1 (en) 2009-10-01 2011-04-07 F. Hoffmann-La Roche Ag Protein a chromatography
EP2583973B1 (en) * 2010-06-21 2018-03-21 Kyowa Hakko Kirin Co., Ltd. Method for purifying protein using amino acid
JP6366502B2 (ja) * 2011-06-01 2018-08-01 ノバルティス アーゲー アフィニティクロマトグラフィーのための、洗浄溶液および方法
AR096713A1 (es) 2013-06-25 2016-01-27 Cadila Healthcare Ltd Proceso de purificación para anticuerpos monoclonales
NZ756750A (en) 2013-09-13 2022-05-27 Genentech Inc Methods and compositions comprising purified recombinant polypeptides
JP2015083558A (ja) 2013-09-18 2015-04-30 東ソー株式会社 抗体吸着剤ならびにそれを用いた抗体の精製方法および識別方法
CA2992420A1 (en) 2015-08-21 2017-03-02 F. Hoffmann-La Roche Ag Method for the reduction of host cell proteins in affinity chromatography

Also Published As

Publication number Publication date
CN107835819A (zh) 2018-03-23
JP2018525408A (ja) 2018-09-06
US20180186865A1 (en) 2018-07-05
SI3337817T1 (sl) 2021-12-31
US20220119499A1 (en) 2022-04-21
HRP20211737T1 (hr) 2022-02-18
PL3337817T3 (pl) 2022-01-17
EP3337817A1 (en) 2018-06-27
JP7073253B2 (ja) 2022-05-23
WO2017032611A1 (en) 2017-03-02
EP3337817B1 (en) 2021-09-15
ES2897965T3 (es) 2022-03-03

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