PL3337817T3 - Sposób zmniejszania zawartości białek komórek gospodarza w chromatografii powinowactwa - Google Patents

Sposób zmniejszania zawartości białek komórek gospodarza w chromatografii powinowactwa

Info

Publication number
PL3337817T3
PL3337817T3 PL16753879T PL16753879T PL3337817T3 PL 3337817 T3 PL3337817 T3 PL 3337817T3 PL 16753879 T PL16753879 T PL 16753879T PL 16753879 T PL16753879 T PL 16753879T PL 3337817 T3 PL3337817 T3 PL 3337817T3
Authority
PL
Poland
Prior art keywords
reduction
host cell
affinity chromatography
cell proteins
proteins
Prior art date
Application number
PL16753879T
Other languages
English (en)
Inventor
Roberto Falkenstein
Wolfgang Koehnlein
Klaus Schwendner
Bernhard SPENSBERGER
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54064133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3337817(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL3337817T3 publication Critical patent/PL3337817T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL16753879T 2015-08-21 2016-08-11 Sposób zmniejszania zawartości białek komórek gospodarza w chromatografii powinowactwa PL3337817T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15181903 2015-08-21
PCT/EP2016/069163 WO2017032611A1 (en) 2015-08-21 2016-08-11 Method for the reduction of host cell proteins in affinity chromatography
EP16753879.2A EP3337817B1 (en) 2015-08-21 2016-08-11 Method for the reduction of host cell proteins in affinity chromatography

Publications (1)

Publication Number Publication Date
PL3337817T3 true PL3337817T3 (pl) 2022-01-17

Family

ID=54064133

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16753879T PL3337817T3 (pl) 2015-08-21 2016-08-11 Sposób zmniejszania zawartości białek komórek gospodarza w chromatografii powinowactwa

Country Status (10)

Country Link
US (2) US20180186865A1 (pl)
EP (1) EP3337817B1 (pl)
JP (1) JP7073253B2 (pl)
CN (1) CN107835819A (pl)
ES (1) ES2897965T3 (pl)
HK (1) HK1251583A1 (pl)
HR (1) HRP20211737T1 (pl)
PL (1) PL3337817T3 (pl)
SI (1) SI3337817T1 (pl)
WO (1) WO2017032611A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017032686A1 (en) 2015-08-21 2017-03-02 F. Hoffmann-La Roche Ag Method for the reduction of host cell proteins in affinity chromatography
CN112876567A (zh) * 2019-11-29 2021-06-01 广东菲鹏制药股份有限公司 Fc融合蛋白及其纯化方法
WO2021147857A1 (en) * 2020-01-20 2021-07-29 Wuxi Biologics (Shanghai) Co., Ltd A novel wash buffer solution for affinity chromatography

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9203459D0 (en) * 1992-02-19 1992-04-08 Scotgen Ltd Antibodies with germ-line variable regions
TWI338009B (en) 2001-10-29 2011-03-01 Genentech Inc Antibodies for inhibiting blood coagulation and methods of use thereof
ES2558303T3 (es) * 2002-09-11 2016-02-03 Chugai Seiyaku Kabushiki Kaisha Método de purificación de proteínas
TW200902555A (en) 2005-01-03 2009-01-16 Hoffmann La Roche Antibodies against IL-13 receptor alpha 1 and uses thereof
DK1876236T3 (da) 2005-04-08 2014-10-20 Chugai Pharmaceutical Co Ltd Antistof som funktionel erstatning for blodkoagulationsfaktor VIII
CN101213211A (zh) 2005-06-17 2008-07-02 惠氏公司 纯化含Fc区蛋白的方法
CN102272154A (zh) 2008-10-29 2011-12-07 惠氏有限责任公司 单域抗原结合性分子的纯化方法
WO2011038894A1 (en) 2009-10-01 2011-04-07 F. Hoffmann-La Roche Ag Protein a chromatography
WO2011162210A1 (ja) 2010-06-21 2011-12-29 協和発酵キリン株式会社 アミノ酸を利用したタンパク質の精製方法
EP2714714B1 (en) * 2011-06-01 2018-06-20 Novartis AG Wash solution and method for affinity chromatography
AR096713A1 (es) 2013-06-25 2016-01-27 Cadila Healthcare Ltd Proceso de purificación para anticuerpos monoclonales
NZ756750A (en) 2013-09-13 2022-05-27 Genentech Inc Methods and compositions comprising purified recombinant polypeptides
JP2015083558A (ja) 2013-09-18 2015-04-30 東ソー株式会社 抗体吸着剤ならびにそれを用いた抗体の精製方法および識別方法
WO2017032686A1 (en) 2015-08-21 2017-03-02 F. Hoffmann-La Roche Ag Method for the reduction of host cell proteins in affinity chromatography

Also Published As

Publication number Publication date
HRP20211737T1 (hr) 2022-02-18
ES2897965T3 (es) 2022-03-03
WO2017032611A1 (en) 2017-03-02
EP3337817A1 (en) 2018-06-27
EP3337817B1 (en) 2021-09-15
JP7073253B2 (ja) 2022-05-23
US20220119499A1 (en) 2022-04-21
SI3337817T1 (sl) 2021-12-31
HK1251583A1 (zh) 2019-02-01
JP2018525408A (ja) 2018-09-06
US20180186865A1 (en) 2018-07-05
CN107835819A (zh) 2018-03-23

Similar Documents

Publication Publication Date Title
IL254965A0 (en) fusion proteins
EP3140763A4 (en) Binding affinity prediction system and method
IL290358A (en) Preparations and methods for detecting host cell proteins
PL3337812T3 (pl) Sposób zmniejszenia zawartości białek komórki gospodarza w chromatografii powinowactwa
ZA201705712B (en) Host cell protein modification
EP3010527A4 (en) Method for assessing protein identity and stability
HUP1500363A2 (en) Method for increasing the galactose content of recombinant proteins
IL263342A (en) A method for stabilizing proteins
EP3297661A4 (en) Method of improving characteristics of proteins
IL250165A0 (en) Cation exchange chromatographic support and method for using it
IL257170B (en) Stable proteins and methods for their design
SG10201801320UA (en) Soluble intein fusion proteins and methods for purifying biomolecules
EP3312278A4 (en) Protein expression method
EP3265470A4 (en) Electrophoresis and electroblotting systems and methods
EP3260862A4 (en) Method for suppressing protein adsorption
IL259181A (en) Opposite ph-salt gradients for improved protein separations
IL259180A (en) Improved protein separation in ion exchange chromatography
GB201503218D0 (en) Particles comprising fusion proteins
EP3299450A4 (en) Induced syncytiotrophoblast and preparation method for progenitor cell thereof
EP3182997A4 (en) Affinity proteins and uses thereof
PL3337817T3 (pl) Sposób zmniejszania zawartości białek komórek gospodarza w chromatografii powinowactwa
GB201506113D0 (en) Method for chromatography
SG10202010606YA (en) Method for reducing the trisulfide level in proteins
EP3188826A4 (en) Systems and methods for assessing therapeutic proteins
GB201502590D0 (en) Method and apparatus for designing proteins