HK1250392A1 - 子癇前期檢測和治療的方法和組合物 - Google Patents

子癇前期檢測和治療的方法和組合物

Info

Publication number
HK1250392A1
HK1250392A1 HK18109766.3A HK18109766A HK1250392A1 HK 1250392 A1 HK1250392 A1 HK 1250392A1 HK 18109766 A HK18109766 A HK 18109766A HK 1250392 A1 HK1250392 A1 HK 1250392A1
Authority
HK
Hong Kong
Prior art keywords
preeclampsia
compositions
detection
treatment
methods
Prior art date
Application number
HK18109766.3A
Other languages
English (en)
Inventor
C‧S‧布希姆斯基
I‧布希姆斯基
C‧G‧格萊柏
Original Assignee
耶魯大學
加利福尼亞大學董事會
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 耶魯大學, 加利福尼亞大學董事會 filed Critical 耶魯大學
Publication of HK1250392A1 publication Critical patent/HK1250392A1/zh

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6866—Interferon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8125—Alpha-1-antitrypsin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90287—Oxidoreductases (1.) oxidising metal ions (1.16)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18109766.3A 2008-10-31 2018-07-27 子癇前期檢測和治療的方法和組合物 HK1250392A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19791408P 2008-10-31 2008-10-31
US20653409P 2009-01-29 2009-01-29

Publications (1)

Publication Number Publication Date
HK1250392A1 true HK1250392A1 (zh) 2018-12-14

Family

ID=42125890

Family Applications (3)

Application Number Title Priority Date Filing Date
HK18109541.5A HK1250061A1 (zh) 2008-10-31 2018-07-23 子癇前期檢測和治療的方法和組合物
HK18109769.0A HK1250393A1 (zh) 2008-10-31 2018-07-27 子癇前期檢測和治療的方法和組合物
HK18109766.3A HK1250392A1 (zh) 2008-10-31 2018-07-27 子癇前期檢測和治療的方法和組合物

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HK18109541.5A HK1250061A1 (zh) 2008-10-31 2018-07-23 子癇前期檢測和治療的方法和組合物
HK18109769.0A HK1250393A1 (zh) 2008-10-31 2018-07-27 子癇前期檢測和治療的方法和組合物

Country Status (4)

Country Link
US (4) US9229009B2 (zh)
CN (12) CN102483418B (zh)
HK (3) HK1250061A1 (zh)
WO (1) WO2010062377A2 (zh)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102483418B (zh) * 2008-10-31 2015-01-07 耶鲁大学 先兆子痫检测和治疗的方法和组合物
CA2779846A1 (en) * 2009-11-04 2011-05-12 Novartis Ag Positively charged species as binding reagents in the separation of protein aggregates from monomers
CA2886489A1 (en) 2011-10-14 2013-04-18 Aarhus Universitet Diagnostic and prognostic use of prombp-complexes
US9340784B2 (en) 2012-03-19 2016-05-17 Ionis Pharmaceuticals, Inc. Methods and compositions for modulating alpha-1-antitrypsin expression
SG11201407667UA (en) 2012-06-27 2015-02-27 Hoffmann La Roche MEANS AND METHODS APPLYING sFlt-1/PlGF OR ENDOGLIN/PlGF RATIO TO RULE-OUT ONSET OF PREECLAMPSIA WITHIN A CERTAIN TIME PERIOD
CA2882687A1 (en) * 2012-09-04 2014-03-13 Pluristem Ltd. Methods for prevention and treatment of preeclampsia
MX366272B (es) * 2013-03-14 2019-07-04 Immucor Gti Diagnostics Inc Metodos y composiciones para diagnosticar preeclampsia.
CN103513042A (zh) * 2013-09-23 2014-01-15 中国科学院动物研究所 用于预测或早期诊断妊娠高血压疾病的试剂盒
CN106662589B (zh) * 2014-03-21 2019-07-30 艾基诺米公司 先兆子痫的早期检测
ES2817417T3 (es) 2014-04-10 2021-04-07 Univ Yale Métodos y composiciones para la detección de proteínas mal plegadas
CN105092854A (zh) * 2014-05-07 2015-11-25 湖州数问生物技术有限公司 体外诊断装置和试剂盒
US20160025737A1 (en) 2014-07-25 2016-01-28 Diabetomics, Llc Biomarkers for assessment of preeclampsia
WO2016176859A1 (zh) * 2015-05-07 2016-11-10 浙江数问生物技术有限公司 体外诊断装置和试剂盒
CA2932204A1 (en) * 2015-06-25 2016-12-25 Alaya Care Inc. Method for predicting adverse events for home healthcare of remotely monitored patients
TWI800009B (zh) * 2015-07-15 2023-04-21 美商蓋斯特維炫股份有限公司 用於檢測折疊錯誤蛋白質之裝置及其使用方法
US20160324920A1 (en) * 2016-06-24 2016-11-10 Ian Gill Bemis Cellular Specific Therapeutic Prion
US11061019B2 (en) * 2017-06-14 2021-07-13 Jinghong Chen High sensitivity optical detection system
CN210123442U (zh) * 2017-12-28 2020-03-03 浙江数问生物技术有限公司 一种检测错误折叠蛋白质的装置
CN110305954B (zh) * 2019-07-19 2022-10-04 广州市达瑞生物技术股份有限公司 一种早期准确检测先兆子痫的预测模型
WO2021178448A1 (en) * 2020-03-02 2021-09-10 Motor Life Sciences, Llc Compositions and methods for diagnosing, preventing, and treating amyotrophic lateral sclerosis in patients with hypofunctional anti-trypsin activity
CN115867807A (zh) * 2020-06-24 2023-03-28 旭化成医疗株式会社 含蛋白质的溶液的评价方法
EP4249914A1 (en) * 2020-11-21 2023-09-27 Shuwen Biotech Co., Ltd. Apparatus and method for detecting misfolded protein in biological sample
CN112582068B (zh) * 2020-12-31 2022-09-20 山东省妇幼保健院 一种用于妊娠期子痫症状的安全装置
WO2024073597A1 (en) * 2022-09-30 2024-04-04 The Board Of Trustees Of The Leland Stanford Junior University Pathology modifying neuromodulation therapy design

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444879A (en) 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US5712103A (en) * 1995-02-13 1998-01-27 Regents Of The University Of California Diagnostic assay for the prediction of preeclampsia
US5998216A (en) 1996-10-01 1999-12-07 Beth Israel Deaconess Medical Center Stabilizing formulation for preserving the integrity of proteins present in a body fluid sampled ex-vivo for evaluation as a specimen
CA2275708A1 (en) 1996-12-23 1998-07-02 Cambridge University Technical Services Limited Diagnosis and treatment of pathological pregnancies
AU2636399A (en) * 1998-02-25 1999-09-15 National University Of Ireland, Cork Hla linked pre-eclampsia and miscarriage susceptibility gene
US6642055B1 (en) * 2000-03-31 2003-11-04 Arbogast Pharmaceuticals, Inc. Method for the prediction of preeclampsia and other diseases
KR100425525B1 (ko) * 2000-11-21 2004-03-30 재단법인서울대학교산학협력재단 조산과 태아감염 및 태아손상을 산전 진단하기 위한진단시약 및 진단키트
US6444435B1 (en) 2000-11-30 2002-09-03 Serim Research Corporation Test strip for determining dialysate composition
CA2448981C (en) * 2001-05-31 2014-03-18 Arete Associates Misfolded protein sensor method
US7355044B2 (en) 2001-10-25 2008-04-08 Agfa-Gevaert N.V. Self-assembling dyes
EP1380290A1 (en) * 2002-07-09 2004-01-14 Universitair Medisch Centrum Utrecht Cross-beta structure pathway and its therapeutic relevance
US20070003552A1 (en) * 2002-07-09 2007-01-04 Gebbink Martijn F B Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation
ES2534294T3 (es) * 2002-07-19 2015-04-21 Beth Israel Deaconess Medical Center Métodos para tratar la preeclampsia
US7435419B2 (en) * 2002-07-19 2008-10-14 Beth Israel Deaconess Medical Center Methods of diagnosing and treating pre-eclampsia or eclampsia
EP1539941A4 (en) * 2002-08-27 2006-11-29 ADZYMES AND THEIR USES
CA2498407A1 (en) 2002-09-12 2004-03-25 The Regents Of The University Of California Immunogens and corresponding antibodies specific for high molecular weight aggregation intermediates common to amyloids formed from proteins of differing sequence
WO2004065629A1 (en) * 2003-01-17 2004-08-05 The Chinese University Of Hong Kong Circulating mrna as diagnostic markers for pregnancy-related disorders
US20050255114A1 (en) * 2003-04-07 2005-11-17 Nuvelo, Inc. Methods and diagnosis for the treatment of preeclampsia
CN1838950A (zh) * 2003-06-23 2006-09-27 神经化学（国际）有限公司 治疗蛋白质聚集疾病的方法
EP1524523A1 (en) * 2003-10-17 2005-04-20 Deutsches Krebsforschungszentrum Stiftung Des Öffentlichen Rechts Use of ADAM 12 for diagnosis and therapy of preeclampsia
DE102004007462A1 (de) * 2004-02-13 2005-09-15 Heinrich-Heine-Universität Düsseldorf Antikörper sowie Verfahren zur Diagnose und Behandlung von Schizophrenie
WO2005093413A2 (en) * 2004-03-22 2005-10-06 Yale University Diagnosis and treatment of preeclampsia
EP1901074B1 (en) * 2004-05-19 2011-07-27 Københavns Universitet Adam12 as marker for fetal Turner Syndrome
CN101263154A (zh) * 2004-11-04 2008-09-10 华盛顿大学 用于治疗蛋白质错折叠及蛋白质聚集疾病的组合物和方法
ATE478602T1 (de) 2004-12-15 2010-09-15 Beth Israel Hospital Nukleinsäuren und polypeptide zur diagnose und behandlung von schwangerschaftskomplikationen
WO2006069373A2 (en) * 2004-12-21 2006-06-29 Yale University Diagnosis of preeclampsia
CA2597912C (en) * 2005-02-15 2013-06-04 Adlyfe, Inc. Method for detecting misfolded proteins and prions
EP1733762A1 (en) 2005-05-25 2006-12-20 3M Espe AG Dental composition for detection of carious tissue, detection method
GB0516527D0 (en) * 2005-08-11 2005-09-21 Arpi Matossian Rogers Peptides
US8263342B2 (en) 2005-10-27 2012-09-11 Yale University Urinary proteomic biomarker patterns in preeclampsia
WO2008015384A1 (en) * 2006-08-04 2008-02-07 Lonza Biologics Plc Method for predicting protein aggregation and designing aggregation inhibitors
US20080118938A1 (en) * 2006-09-06 2008-05-22 Lisbell Estrada Methods and Compositions for the Detection of Protein Folding Disorders
EP1944611A1 (en) * 2007-01-11 2008-07-16 Université de la Méditerranée Biomarker for the medicine and the biology of the reproduction
EP2236512A1 (en) * 2007-04-18 2010-10-06 Biochromix AB Binding of pathological forms of proteins using conjugated polyelectrolytes
CN101224207A (zh) * 2007-10-12 2008-07-23 中国科学院上海有机化学研究所 具有诱导自吞噬治疗错误折叠蛋白聚集所致疾病的药物及其筛选方法
US20110065139A1 (en) 2007-11-27 2011-03-17 Jacob Mullerad diagnostic device for identifying rupture of membrane during pregnancy
CN102483418B (zh) * 2008-10-31 2015-01-07 耶鲁大学 先兆子痫检测和治疗的方法和组合物
CN103012599B (zh) 2012-11-28 2015-04-29 龙岩九健生物芯片技术研究所 一种调节硝酸纤维素硝化取代度的方法
ES2817417T3 (es) 2014-04-10 2021-04-07 Univ Yale Métodos y composiciones para la detección de proteínas mal plegadas

Also Published As

Publication number Publication date
US10048276B2 (en) 2018-08-14
US9229009B2 (en) 2016-01-05
CN105044347B (zh) 2017-06-09
WO2010062377A3 (en) 2010-08-05
CN107677829A (zh) 2018-02-09
HK1250061A1 (zh) 2018-11-23
CN110187119B (zh) 2022-07-29
US20110280863A1 (en) 2011-11-17
US20160097775A1 (en) 2016-04-07
HK1250393A1 (zh) 2018-12-14
US20170356920A1 (en) 2017-12-14
CN104777308A (zh) 2015-07-15
CN104777307A (zh) 2015-07-15
CN110187119A (zh) 2019-08-30
CN107677828A (zh) 2018-02-09
CN102483418B (zh) 2015-01-07
CN102483418A (zh) 2012-05-30
CN110187121B (zh) 2022-07-01
CN107677830A (zh) 2018-02-09
CN105044347A (zh) 2015-11-11
CN104777308B (zh) 2017-04-12
CN105021821A (zh) 2015-11-04
CN110187120B (zh) 2022-07-01
WO2010062377A2 (en) 2010-06-03
CN110187120A (zh) 2019-08-30
CN105021821B (zh) 2018-05-11
CN110208540B (zh) 2024-02-09
CN110187121A (zh) 2019-08-30
US20210255192A1 (en) 2021-08-19
US11125758B2 (en) 2021-09-21
CN110208540A (zh) 2019-09-06
CN104777307B (zh) 2019-10-18

Similar Documents

Publication Publication Date Title
HK1250393A1 (zh) 子癇前期檢測和治療的方法和組合物
HK1247821A1 (zh) 用於預防或治療眼科病症的方法和組合物
EP2361089A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALTERED FUNCTION OF -SYNUCLEINE
EP2655334A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES
HK1144319A1 (zh) 檢測轉錄失真抗體的方法和組合物
HK1159498A1 (zh) 用於治療癌症的方法和組合物
HK1166305A1 (zh) 用於治療炎症的組合物及方法
EP2331123A4 (en) COMPOSITIONS AND METHODS FOR TREATING HEPATITIS C
IL210097A0 (en) Compositions and methods for treating unfluenza
EP2408465A4 (en) METHOD AND COMPOSITIONS FOR DETECTING CANCER
ZA200905101B (en) Diagosis and treatment of preeclampsia
EP2429584A4 (en) TREATMENT PROCEDURE AND COMPOSITIONS
EP2504428A4 (en) METHOD AND COMPOSITIONS FOR TREATING OXALATE-MEDIATED SUFFERING
EP2340027A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
HK1140019A1 (en) Compositions and methods of detection
EP2249789A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF XEROSOMY
IL214349A0 (en) Compositions and methods for the treatment of cancer
IL210840A0 (en) Methods and compositions for treating and preventing autoimmune diseases
EP2437738A4 (en) METHOD AND COMPOSITIONS FOR CANCER TREATMENT
EP2285398A4 (en) METHOD AND COMPOSITIONS FOR TREATING ADIPOSITAS
EP2411031A4 (en) Methods and compositions for the treatment of cancer
EP2512504A4 (en) COMPOSITION AND THERAPEUTIC METHOD
EP2424549A4 (en) COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING UROLITHIASIS AND ASSOCIATED SUFFERINGS
GB0808326D0 (en) Compositions and methods for the treatment of fybromyalgia
GB0808730D0 (en) Compositions and methods for the prevention and treatment of schistosomiasis