HK1248772A1 - 序列特異性檢測和表型確定 - Google Patents

序列特異性檢測和表型確定

Info

Publication number
HK1248772A1
HK1248772A1 HK18108242.9A HK18108242A HK1248772A1 HK 1248772 A1 HK1248772 A1 HK 1248772A1 HK 18108242 A HK18108242 A HK 18108242A HK 1248772 A1 HK1248772 A1 HK 1248772A1
Authority
HK
Hong Kong
Prior art keywords
sequence
specific detection
phenotype determination
phenotype
determination
Prior art date
Application number
HK18108242.9A
Other languages
English (en)
Inventor
Diego Ariel Rey
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1248772A1 publication Critical patent/HK1248772A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK18108242.9A 2015-04-30 2018-06-27 序列特異性檢測和表型確定 HK1248772A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562155011P 2015-04-30 2015-04-30
PCT/EP2016/059518 WO2016174151A1 (en) 2015-04-30 2016-04-28 Sequence-specific detection and phenotype determination

Publications (1)

Publication Number Publication Date
HK1248772A1 true HK1248772A1 (zh) 2018-10-19

Family

ID=55953128

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18108242.9A HK1248772A1 (zh) 2015-04-30 2018-06-27 序列特異性檢測和表型確定

Country Status (9)

Country Link
US (2) US10227661B2 (zh)
EP (1) EP3289100B1 (zh)
JP (1) JP6826048B2 (zh)
CN (1) CN107532215A (zh)
CA (1) CA2983217C (zh)
ES (1) ES2761631T3 (zh)
HK (1) HK1248772A1 (zh)
SG (1) SG11201708841SA (zh)
WO (1) WO2016174151A1 (zh)

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US9737604B2 (en) 2013-09-06 2017-08-22 President And Fellows Of Harvard College Use of cationic lipids to deliver CAS9
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US9228207B2 (en) 2013-09-06 2016-01-05 President And Fellows Of Harvard College Switchable gRNAs comprising aptamers
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AU2015298571B2 (en) 2014-07-30 2020-09-03 President And Fellows Of Harvard College Cas9 proteins including ligand-dependent inteins
US9879328B2 (en) * 2014-11-21 2018-01-30 GeneWeave Biosciences, Inc. Mechanisms of antimicrobial susceptibility
CN108513575A (zh) 2015-10-23 2018-09-07 哈佛大学的校长及成员们 核碱基编辑器及其用途
EP3436196A2 (en) 2016-03-28 2019-02-06 The Charles Stark Draper Laboratory, Inc. Bacteria identification and antibiotic susceptibility profiling device
WO2018027078A1 (en) 2016-08-03 2018-02-08 President And Fellows Of Harard College Adenosine nucleobase editors and uses thereof
CA3033327A1 (en) 2016-08-09 2018-02-15 President And Fellows Of Harvard College Programmable cas9-recombinase fusion proteins and uses thereof
WO2018039438A1 (en) 2016-08-24 2018-03-01 President And Fellows Of Harvard College Incorporation of unnatural amino acids into proteins using base editing
KR20240007715A (ko) 2016-10-14 2024-01-16 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 핵염기 에디터의 aav 전달
US10745677B2 (en) 2016-12-23 2020-08-18 President And Fellows Of Harvard College Editing of CCR5 receptor gene to protect against HIV infection
EP3592853A1 (en) 2017-03-09 2020-01-15 President and Fellows of Harvard College Suppression of pain by gene editing
JP2020510439A (ja) 2017-03-10 2020-04-09 プレジデント アンド フェローズ オブ ハーバード カレッジ シトシンからグアニンへの塩基編集因子
SG11201908658TA (en) 2017-03-23 2019-10-30 Harvard College Nucleobase editors comprising nucleic acid programmable dna binding proteins
US11560566B2 (en) 2017-05-12 2023-01-24 President And Fellows Of Harvard College Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
US11732274B2 (en) 2017-07-28 2023-08-22 President And Fellows Of Harvard College Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE)
US11319532B2 (en) 2017-08-30 2022-05-03 President And Fellows Of Harvard College High efficiency base editors comprising Gam
CN111757937A (zh) 2017-10-16 2020-10-09 布罗德研究所股份有限公司 腺苷碱基编辑器的用途
CN107904208B (zh) * 2017-12-25 2019-11-01 云舟生物科技（广州）有限公司 细胞表型研究用的细胞克隆及其筛选方法和应用
US10450616B1 (en) 2018-05-09 2019-10-22 Talis Biomedical Corporation Polynucleotides for the amplification and detection of Chlamydia trachomatis
CN109628616A (zh) * 2018-12-17 2019-04-16 博奥生物集团有限公司 用于检测碳青霉烯类耐药基因ndm1-24亚型的lamp引物组合及其应用
JP2022515451A (ja) * 2018-12-27 2022-02-18 エフ．ホフマン－ラ ロシュ アーゲー アシネトバクター・バウマンニの検出のための、非複製的形質導入粒子及び形質導入粒子に基づくレポーター系
CN113227403A (zh) * 2018-12-29 2021-08-06 豪夫迈·罗氏有限公司 含铁抗菌素类在抗生素敏感性测定中用于限制交叉反应性以及改善细菌鉴定之用途
DE112020001342T5 (de) 2019-03-19 2022-01-13 President and Fellows of Harvard College Verfahren und Zusammensetzungen zum Editing von Nukleotidsequenzen
WO2020245123A1 (en) * 2019-06-06 2020-12-10 F. Hoffmann-La Roche Ag Use of peptidomimetic antimicrobial peptides to limit cross-reactivity and improve bacterial identification in antibiotic susceptibility assays
US10954572B2 (en) 2019-07-25 2021-03-23 Talis Biomedical Corporation Polynucleotides for the amplification and detection of Neisseria gonorrhoeae
US11891662B2 (en) 2019-12-02 2024-02-06 Talis Biomedical Corporation Polynucleotides for amplification and detection of human beta actin
EP4146804A1 (en) 2020-05-08 2023-03-15 The Broad Institute Inc. Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence

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Also Published As

Publication number Publication date
US10822664B2 (en) 2020-11-03
CN107532215A (zh) 2018-01-02
EP3289100B1 (en) 2019-10-09
JP6826048B2 (ja) 2021-02-03
US10227661B2 (en) 2019-03-12
ES2761631T3 (es) 2020-05-20
US20190127810A1 (en) 2019-05-02
US20160319378A1 (en) 2016-11-03
CA2983217A1 (en) 2016-11-03
EP3289100A1 (en) 2018-03-07
JP2018520640A (ja) 2018-08-02
CA2983217C (en) 2022-01-11
SG11201708841SA (en) 2017-11-29
WO2016174151A1 (en) 2016-11-03

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